Best Startups to Work in San Francisco in 2026

Binti builds modern software to help every child have a safe, loving, and stable family.

550+ child welfare agencies across 36 states use Binti's tools to care for over 47% of children in child welfare in the US. Our software supports end-to-end workflows in child welfare, from helping agencies efficiently recruit, license, and ...

Cortex is the enterprise Internal Developer Portal built to accelerate the path to engineering excellence. Abstract away complexity in your platform to ensure ownership, enforce standards, and unlock developer self-service, in weeks—not years.

Galileo is the AI observability and evaluation platform that helps engineers ship reliable agents.

With one line of code, Galileo provides instant insight into multi-agent behavior so teams can find & fix errors quickly. Galileo provides automated testing in the development lifecycle to prevent regressions. And Galileo is ...

Our mission is to enable every organization to innovate faster by harnessing the power of automation. From Healthcare to Education, Supply Chain to Internet of Things, developers use Ascend to build innovative products that change the world around us.

Our team at Ascend.io radiates passion and a deeply-rooted excitement to ...

Doppler is the uncomplicated way to sync, manage, orchestrate, and rotate secrets across any environment or app config with easy-to-use tools.

Course Hero is an online learning platform with over 60 million course-specific study resources contributed by our community of students and educators, and produced by our team of educational content specialists in collaboration with subject experts.

You’ll find practice problems, study guides, videos, class notes, and step-by-step ...

Truffle Security is a cybersecurity company that offers open-source and enterprise solutions for finding and remediating leaked software credentials. Our secret-scanning engine, Truffle Hog, identifies and addresses credentials and passwords before hackers are able to find and exploit them. Detecting these credentials early allows companies to ...

Globality was founded with a simple but lofty goal: to use AI to transform enterprise spending into a smarter, fairer process, and create more efficient, inclusive markets around the globe. Globality is the future of enterprise spending: an AI solution that is guaranteed to empower employees, bolster the bottom line, and improve business outcomes ...

Gynger is a cash flow management solution with embedded financing that gives B2B technology vendors the power to offer flexible payment terms to customers while securing up front payment.

With Gynger, finance leaders can leverage a combination of actionable insights and capital to optimize day-to-day cash flows, accelerate deal ...

Robust Intelligence's mission is to eliminate risks introduced by AI technologies. We consider the effect of AI risk not only on organizations but also on our society. Our product RIME has the ability to monitor and detect AI failures. We’ve built AI Stress Testing to detect a specific model’s weaknesses in the pre-deployment stage. In the ...

Matik automates the creation and sending of Google/PowerPoint decks with personalized text, images, charts, tables, and AI-powered insights. Just tell Matik who it's for and Matik will query the data to create data-driven content, like QBRs, EBRs, renewal decks, pitch decks, and ROI one-pagers.

Open Source has become the critical supplier for modern software companies, changing everything about how people think about their code. FOSSA builds the infrastructure for modern teams to be successful with open source.

FOSSA's flagship product helps teams track the open source used in their code and automate license scanning ...

At Render we are building a powerful, easy-to-use cloud platform to host anything online: from simple static sites to complex applications with dozens of microservices. Render offers the flexibility of traditional cloud providers without their complexity and maintenance headaches so developers and businesses can focus on building products instead ...

American medicine is the best in the world. But the American healthcare system is challenged by high administrative costs that burden patients, health systems, and insurance companies with unnecessary expenses. We are focused on addressing those challenges.

We use GenAI to improve the most pressing financial pain points in the ...

Squint is the Manufacturing Intelligence Platform that the world's leading manufacturers use to capture expert knowledge, unlock operator performance, and analyze production insights. Operators love Squint because it uniquely combines spatial computing, LLMs, and human expertise into a magical experience.

Our story starts with ...

Machinify is an AI start-up in the Healthcare space. Our software platform leverages the latest advances in machine learning, large language models, data analytics, and cloud processing to solve previously intractable problems in the healthcare industry impacting millions of lives.

Distributional’s active AI testing platform enables AI product teams to identify, understand and address AI risk before production so they can ship high quality AI products with confidence. We've raised $30M in the past year to accomplish our mission.

Noyo is building the digital infrastructure to bring health insurance enrollment into the modern era. Noyo replaces today’s manual data entry and cumbersome legacy systems with a powerful API platform that enables faster, more accurate data exchange between health insurance platforms and their carrier partners.

Nova Credit is a credit infrastructure and analytics company that enables businesses to grow responsibly through alternative credit data. As a Consumer Reporting Agency (CRA), Nova Credit leverages its unique data infrastructure, compliance framework, and credit expertise to help lenders fill critical gaps in traditional credit analytics. The ...

Check is a payroll-as-a-service API that lets you embed payroll directly in your vertical SaaS, HR, or time-tracking platform. Our API abstracts away the complexities of running payroll: tax calculation, remittance, and filing, plus the movement of money between companies and employees. This enables companies to easily build fully integrated ...

Moov is a payments infrastructure platform making it easy to accept, store, send, and spend money all from a single, elegantly-designed API. Instead of stitching together multiple vendors, software companies simply add Moov to their products to get the latest in payment technology, user onboarding, licensing, compliance, and more.

Sprig is the leading product experience insights platform for teams building innovative, user-driven digital products. Our mission is to empower teams to make experiences that matter.

Making awesome products requires working with awesome people. At Sprig, our values are at the core of everything we do, say, and create as a team. ...

Subscription companies are losing 10%+ of revenue to failed payments—billions of dollars a year—a problem known as “Involuntary churn.”

Butter is on a mission to end involuntary churn. Using machine learning we help the greatest subscription companies in the world—Fabletics, The Athletic, Savage x Fenty, Found, Tonal, Hairstory— ...

Since its launch in 2016, Jackpot.com has become a world leader in the online lottery sector, with the goal of fundamentally changing the lottery experience through innovation and variety. Besides offering players the opportunity to bet on the outcomes of the world’s biggest lotteries, Jackpot.com offers an enriched gaming experience through ...

Privacy is messy. And complicated.

Organizations today rely on dozens of inter-connected data platforms-- SaaS apps, data lakes, and hosted databases -- making it difficult to know where all of a single person's data could be. But with the right solution, it is possible to make sense of privacy, and turn it into an advantage to ...

Orb is the Revenue Design platform that helps SaaS and GenAI companies design, price, and execute monetization; from contracts and usage to billing, invoicing, and reporting. It is built for Revenue Architects, the product, finance, engineering, and sales leaders who shape how revenue is created. Legacy billing systems are rigid and slow, often ...

Cavnue is building smart roads for smart vehicles, and future-proofing the nation’s roadways.

The interstate highway system defined mobility in the second half of the 20th century. Now, transportation is changing again. Mobility in the 21st century will be defined by intelligent, connected, and autonomous vehicles and while billions ...

At Weave, we are building the backbone for modern drug development. Drug development teams deserve tools that match the pace and complexity of their science, and our AI-native platform is designed to support them at every step. We focus on regulatory workflows, helping biotech and pharma organizations bring clarity and speed to documentation so ...

Tonic.ai frees developers to build with safe, high-fidelity synthetic data to accelerate software and AI innovation while protecting data privacy. Through industry-leading solutions for data synthesis, de-identification, and subsetting, our products enable on-demand access to realistic structured, semi-structured, and unstructured data for ...

Unlearn is advancing AI to eliminate trial and error in medicine, starting with reinventing clinical trials for the 21st century. We create AI-generated digital twins of individual trial participants that are forecasts of their future health outcomes. Digital twins of participants are used to run smaller, more efficient clinical trials that help ...

Parade is the leading capacity management platform for freight brokerages. By integrating with our customers' technology stack, we're able to create a single pane of glass that enables freight brokers to automate and scale their business. Parade's platform is built using cutting edge AI, Machine Learning, and advance automation ...

We automate and streamline repetitive, manual work so finance organizations can focus on driving the business forward. We're proudly backed by industry-leading investors, executives, and finance teams.

Craft illuminates the path to global supply chain resilience. We empower businesses to strengthen their supplier networks and supply chains with the industry's most trusted and comprehensive data fabric and advanced risk mitigation engine. Our easy-to-use platform provides 360-degree visibility to quickly explore and evaluate supplier ...

Fractal provides aspiring entrepreneurs with a business idea, a highly capable and complementary co-founder, capital, and ongoing support. Together, we’ll create fast-growing vertical SaaS companies that help modernize overlooked American industries.

You.com is an AI-powered search and productivity platform that helps users find information, create content, and accomplish tasks efficiently - all in one place. By combining advanced AI technology with a customizable search experience, You.com empowers people to search, write, code, and summarize content while maintaining control over their ...

Stellic is a leading student success and academic planning platform used by over 90 higher education institutions worldwide and more than 1 million students. We empower students, advisors, and administrators with modern tools to streamline degree progress, automate transfer evaluations, and make data-informed decisions that drive completion and ...

We work with global corporate partners to identify the most pressing challenges that they, and broader society, face. Inspired by these complex problems, we launch startups built by proven entrepreneurs, product leaders and technologists that use their agility and talent to develop transformative solutions. After these companies have matured and ...

Opto Investments (“Opto”) are engineering the future of private markets, offering the solution for wealth managers to efficiently build and manage differentiated private investment programs.

Opto’s end-to-end technology solution dramatically streamlines building, fundraising for, and managing a bespoke private markets fund or ...

On Aalto, buyers and sellers directly connect in a new, tech-enabled way that helps everyone save time, stress, and money.

Our mission is to build a place where buyers and sellers come together to accomplish their homeownership goals through a trusted, flexible, and transparent experience.

Aalto has raised over $17M ...

Xage is a global leader in zero trust access and protection on a mission to pioneer a secure tomorrow. Control access and prevent attacks in the cloud, in the data center, at the remote operational edge anywhere on Earth, and even in orbit with the Xage Fabric Platform. Xage is easy to manage and can be deployed in a day, giving users easy and ...

Stytch is the most powerful identity platform built for developers. By powerful, we mean:

**Comprehensive:** Stytch has everything you need to identify, authenticate, and manage your users, including fraud prevention tools like device fingerprinting.
**Adaptable:** Stytch is the only auth provider that enables you to build ...

The world is moving towards more standardized, open, and interconnected data systems. However, employment infrastructure remains complex, closed, and fragmented.

Our mission is to democratize access to the infrastructure that underpins the employment sector and unlock much-needed innovations and create tremendous economic ...

Beautiful.ai is presentation software that makes it easy to turn your ideas into beautiful visual stories. Our design-AI has been taught the rules of good design and applies them in real-time as you add or edit content; making it easier to build stunning visual presentations that look professionally designed 10x faster.

Parkade's core focus is multi-family buildings and offices, allowing management to easily lease spots digitally through our app to residents, guests and employees. And, when people lease assigned spots long-term, they can reshare their spot when it's vacant — hugely increasing parking capacity and reliability. We are replacing ...

Manufacturing Execution Systems (MES) have never been human-centric. They are known for poor data management, broken traceability, and not designed for the average factory worker. Not anymore - we’ve fixed it. Pico MES is a fresh approach to factory operating systems, enabling a connected environment with limitless factory tools and capturing data ...

About Airvet:
Founded in 2018, Airvet provides 24/7 access to video visits and chats with thousands of licensed veterinarians and pet care providers, delivered as a highly valued employee benefit to companies like Adobe, Ceridian and Rexford Industrial.

Airvet is the #1 rated pet telemedicine app in the App Store with over 7, ...

Tired of taking manual screenshots or recording (and re-recording…) videos for documentation? We hear you. Tango takes the pain out of documenting processes by automatically generating how-to guides while you work.

Easily share and scale your team's knowledge—all while conducting business as usual. No more disruptions, ...

WorkWhile is an AI-powered next generation labor platform that helps businesses in light industrial, hospitality, and events achieve over 90% fill rates and reduce no-shows through AI and predictive machine learning. We ensure seamless shift execution with trained, on-demand workers supported by on-site leads, real-time performance monitoring, and ...

Every day, thousands of brain images and signals are captured during clinical trials and in the course of routine patient care. Our software platform helps partners in med-tech and pharma ingest, organize, and analyze large amounts of brain data, all on state-of-the-art secure cloud infrastructure. Enabled by brain data, StrivePD, our patient and ...

Onfleet helps businesses around the globe power their deliveries.

Our mission is to make it easy for every retailer to offer fast, affordable, and delightful delivery to their customers.

Our software platform includes intuitive smartphone apps for drivers, a powerful modern web dashboard for dispatchers, and automatic ...