Top St. Paul, MN Startups (10,000+)

Biotechnology is rewriting life as we know it, from the medicines we take, to the crops we grow, and the household goods that we rely on every day. But moving at the new speed of science requires better technology. Benchling’s mission is to unlock the power of biotechnology. The world’s most innovative biotech companies use Benchling’s R&D Cloud to power the...

PNC Bank is part of one of the largest diversified financial services institutions in the United States. With a coast-to-coast presence, PNC is organized around its customers and communities for strong relationships and local delivery of retail and business banking including a full range of lending products; specialized services for corporations and government entities, including corporate banking, real estate finance...

Alliant is unlike any other financial institution — a digital credit union that wows our members. We’re boldly disrupting banking norms to do good for our members, employees and communities. With 90 years of history and more than $19 billion in assets, Alliant Credit Union is the largest credit union in Illinois and one of the largest in the U.S. Our industry-leading...

It’s curious to think of innovation and stability co-existing. But we pair a 100-year track record of success with a hunger to do things differently. Everyone is in the work — tackling complex problems where your impact can build back or build up the communities we serve. We fill our halls with curious minds from all walks of life. Our...

Artera, a SaaS leader in digital health, transforms patient experience with AI-powered virtual agents (voice and text) for every step of the patient journey. Trusted by 1,000+ provider organizations — including specialty groups, FQHCs, large IDNs and federal agencies — engaging 100 million patients annually. Artera’s virtual agents support front desk staff to improve patient access including self-scheduling, intake, forms,...

Apex Fintech Solutions provides the tools and services that enable hundreds of clients to launch, scale, and support digital investing for tens of millions of end investors. The company provides essential infrastructure and a comprehensive ecosystem of cloud-based products to enable and streamline trading, wealth management, cost basis, tax reporting, and, through its subsidiary Apex Clearing™, custody and clearing. For...

PrizePicks is the fastest-growing sports company in North America according to the 2022 Inc. 5000 rankings and the largest independent skill-based fantasy sports operator in North America. PrizePicks was also awarded a Best Places to work certification in 2025. The company was recognized as the Fantasy Sports Business of the Year Award by the Fantasy Sports & Gaming Association and...

Grocery TV is the leading in-store retail media platform. Over 120 retailers partner with Grocery TV to modernize their stores and drive incremental revenue, while upholding a high-quality shopper experience. Grocery TV handles the complexities of operating an in-store media network so retailers can focus on what they do best—serving their customers. Reaching 1 in 4 Americans across nearly 6,000...

OppFi is a leading tech-enabled digital finance platform that works with banks to provide financial products and services for everyday Americans. Through a transparent and responsible platform, which includes financial inclusion and excellent customer experience, the Company supports consumers who are turned away by mainstream options to build better financial health. OppFi maintains an A+ rating from the Better Business Bureau...

Securing The Freedom of Operations Headquartered in Colorado, Sierra Space is a mission-proven Defense Tech company delivering satellite platforms, critical subsystems, reusable spaceplanes, hypersonic technologies, propulsion systems, and infrastructure for the nation’s most critical missions. With more than three decades of heritage and a record of flight-proven success in space, Sierra Space is trusted by U.S. National Security, Civil customers, and global...

Fora is the modern travel agency, redefining what it means to be a travel advisor in today’s world. We’re a next-generation platform that provides a comprehensive, business-in-a-box solution—combining cutting-edge technology, personalized training, a vibrant community, and exclusive industry partnerships—all designed to empower anyone with a passion for travel to turn that passion into a thriving business. Whether you're a travel...

Worksmith is a software-enabled marketplace connecting commercial tenants and property owners/managers with qualified local service providers for repairs, maintenance, cleaning and creative services. We currently serve over 5,000 locations for leading brands like Burberry, Nespresso, Faherty Brand, Tiffany & Co., Pandora, Lovisa and Louis Vuitton. As of June 30th, Worksmith acquired Progress Retail, a leading retail operations and learning platform delivering...

Gradient AI is revolutionizing Group Health and P&C insurance with AI-powered solutions that help insurers predict risk more accurately, improve profitability, and automate underwriting and claims. Our SaaS platform taps into one of the industry’s largest data lakes—tens of millions of policies and claims—to deliver deep, actionable insights. Trusted by leading carriers, MGAs, TPAs, and self-insured employers, Gradient AI has...

Dynatrace lets customers understand their business like never before, so they can see beyond the complexity, find and fix problems faster and automate manual tasks with Al — so they can focus on what truly matters: running their business.

Hometap is on a mission to make homeownership less stressful and more accessible. Our home equity investment product provides homeowners with a fast, simple, and straightforward way to access the equity in their home without taking out a loan or having to sell. By investing alongside homeowners, Hometap offers debt-free cash in exchange for a share of their home’s future...

Bectran is an industry-leading SaaS platform which has grown rapidly to become the companion toolkit for the Credit Department just as a CRM is for the Sales Department. Recognized as a top innovator in the credit software industry, Bectran has been described by credit professionals as "the future of the credit department."​

At Affirm, we help people say yes to the things that matter with flexible, transparent ways to pay over time. No hidden fees, no compound interest, and no fine print—just a smarter way to spend.

At Vail we develop innovative technology to enhance the way people communicate. Our mission is to create business value for our clients and growth opportunities for our employees by developing solutions that inspire people to interact freely and authentically.

Sage is an innovative, one-of-a-kind operations management system that transforms how senior living communities deliver care. Unlike traditional nurse call systems, Sage offers a comprehensive platform that provides real-time insights into care delivery and operational efficiency. Our technology empowers caregivers with the tools and data they need to provide personalized care while boosting productivity. By leveraging real-time staffing data and...

Attain is the most trusted and comprehensive source for permissioned, real-time purchase data in the United States. By connecting directly with over 10 million consumers, Attain delivers unmatched accuracy and scale across audience activation, insights, and in-flight optimization, and measurement, helping marketers tie every dollar of media to real-world sales outcomes. Attain’s portfolio of owned and operated apps, spanning financial...