Top Senior Python Jobs

Reposted 5 Days AgoSaved
In-Office or Remote
McLean, VA, USA
Senior level
Senior level
Information Technology
A Senior Python Developer responsible for integrating applications, building APIs, microservices, and mentoring junior developers while working in an Agile team environment.
Top Skills: AWSDockerElasticsearchFastapiJavaScriptJqueryKubernetesPodmanPythonSolrSQLTerraform
Reposted 6 Days AgoSaved
Remote
United States
Senior level
Senior level
Travel
As a Staff Software Engineer, you’ll lead the design and reliability of Duetto's data lakehouse, evolving data systems using Python and AWS, ensuring data quality, and implementing AI-driven solutions.
Top Skills: AirflowAWSDatadogDockerGithub ActionsGlueIcebergPysparkPythonSagemakerSentrySumo LogicTerraform
Reposted 6 Days AgoSaved
In-Office
Conshohocken, PA, USA
Senior level
Senior level
Cloud • Mobile • Software • Design
The Senior Software Engineer will design, develop, and implement software solutions for law enforcement, leading projects and mentoring junior engineers in a collaborative Agile Scrum environment.
Top Skills: Python
Reposted 7 Days AgoSaved
In-Office
2 Locations
115K-195K Annually
Senior level
115K-195K Annually
Senior level
Information Technology • Software • Database
Maintain and improve the LangChain Python package, enhance documentation, assist users, and build example applications.
Top Skills: Python
Reposted 7 Days AgoSaved
In-Office
Boise, ID, USA
140K-175K Annually
Senior level
140K-175K Annually
Senior level
Software • Web3
As a Senior Full Stack Engineer, you will lead the design and implementation of scalable serverless backend services using Python and AWS technologies, focusing on AI integration and event-driven architecture, while also mentoring team members and enhancing development practices.
Top Skills: Ai/Ml ToolsAngularAws ServerlessCi/CdDynamoDBEventbridgeLambdaNode.jsPythonReactSqsTerraformVue
Reposted 7 Days AgoSaved
In-Office
Seattle, WA, USA
140K-175K Annually
Senior level
140K-175K Annually
Senior level
Software • Web3
Lead the design and implementation of scalable backend services using Python and AWS technologies. Collaborate with teams, implement best practices, and mentor junior engineers while integrating AI tools into the development process.
Top Skills: Api GatewayAWSAws LambdaCi/CdCloudFormationDynamoDBEventbridgeInfrastructure As CodePythonSqsTerraform
Reposted 7 Days AgoSaved
In-Office
Los Angeles, CA, USA
140K-175K Annually
Senior level
140K-175K Annually
Senior level
Software • Web3
The Senior Full Stack Engineer will lead the development of scalable backend services using Python and AWS Serverless, mentor team members, and integrate AI tools into the software development lifecycle.
Top Skills: Ai ToolsAngularAWSCi/CdCloudFormationDynamoDBEventbridgeKinesisLambdaNode.jsPythonReactSagemakerSqsStep FunctionsTerraformVue
Reposted 7 Days AgoSaved
In-Office
Phoenix, AZ, USA
140K-175K Annually
Senior level
140K-175K Annually
Senior level
Software • Web3
As a Senior Full Stack Engineer, you’ll lead software development, build scalable backend services using Python and AWS, and integrate AI in workflows while mentoring others.
Top Skills: Ai/Ml ToolsAws LambdaCloudFormationDynamoDBEventbridgeGithub CopilotNode.jsPythonSqsTerraform
Reposted 7 Days AgoSaved
In-Office
Bozeman, MT, USA
140K-175K Annually
Senior level
140K-175K Annually
Senior level
Software • Web3
As a Senior Full Stack Engineer, you will lead the development of scalable backend services, work with serverless architectures and AI tools, and mentor junior engineers. Responsibilities include architectural design, code implementation, and ensuring security and performance best practices are upheld.
Top Skills: Ai ToolsAws LambdaCi/CdCloudFormationDynamoDBEventbridgeNode.jsPythonSqsTerraform
Reposted 7 Days AgoSaved
In-Office
San Jose, CA, USA
140K-175K Annually
Senior level
140K-175K Annually
Senior level
Software • Web3
As a Senior Full Stack Engineer, you will lead software development from design to deployment, focusing on scalable services using Python and AWS technologies, while integrating AI tools and mentoring younger engineers.
Top Skills: Aws Api GatewayAws DynamodbAws LambdaCloudFormationEventbridgeNode.jsPythonSqsTerraform
Reposted 7 Days AgoSaved
In-Office
New York, NY, USA
Senior level
Senior level
Information Technology • Software
The role involves design and development of multi-tier applications using Java and C++, requiring knowledge of Python and derivatives domain.
Top Skills: C++JavaPython
Reposted 7 Days AgoSaved
In-Office
New York, NY, USA
Senior level
Senior level
Information Technology • Software
The role requires a senior developer with expertise in Java and C++, and knowledge of Python. Responsibilities include designing and developing multi-tier applications and handling regulatory projects.
Top Skills: C++JavaPython
New

Track Smarter, Apply Better.

Ditch the spreadsheets. Organize your job search with our freeApplication Tracker.

Use For Free
Application Tracker Preview
Reposted 7 Days AgoSaved
In-Office
New York, NY, USA
Senior level
Senior level
Information Technology • Software
The role involves backend development using SQL, mentoring junior staff, participating in project delivery, and ensuring robust team processes.
Top Skills: NetezzaObject DatabasesPerlPowershellPythonRubySQLUnix
Reposted 7 Days AgoSaved
Remote
United States
139K-203K Annually
Senior level
139K-203K Annually
Senior level
Artificial Intelligence • Information Technology • Machine Learning • Marketing Tech • Software • Biotech • Design
Develop and maintain backend solutions, ensuring performance, security, and regulatory compliance, while collaborating in cross-functional teams.
Top Skills: AWSFastapiPython
8 Days AgoSaved
In-Office
Tampa, FL, USA
114K-171K Annually
Senior level
114K-171K Annually
Senior level
Fintech • Financial Services
Lead design and hands-on development of scalable, high-performance Python applications for market and regulatory risk. Architect distributed systems, enforce SDLC and secure coding, build CI/CD pipelines, integrate with cloud and DevOps, collaborate with Risk/Quants/FO, and deliver stress-testing and regulatory risk solutions under tight deadlines.
Top Skills: AngularSparkAWSAzureBitbucket PipelinesCassandraClaudeCopilotDevinDjangoDockerFastapiFlaskGCPGeminiGitGithub ActionsGitlab CiGptHadoopHugging FaceJenkinsKafkaKubernetesLangchainLanggraphLlamaindexMongoDBOraclePostgresPytestPython 3.XPyTorchReactRedisRest ApisScikit-LearnSQL ServerTensorFlowUnittestUnixVector DbsVue
8 Days AgoSaved
In-Office
New York, NY, USA
177K-265K Annually
Senior level
177K-265K Annually
Senior level
Fintech • Financial Services
Lead design and hands-on delivery of scalable, high-performance Python applications for market and regulatory risk. Architect distributed systems, implement CI/CD, secure REST APIs, collaborate with quants and DevOps, and drive Stress Testing and Regulatory Risk projects under tight deadlines.
Top Skills: Agentic Ai ToolsAngularSparkAWSAzureBitbucket PipelinesCassandraClaudeDevinDjangoDockerFastapiFlaskGCPGitGithub ActionsGithub CopilotGitlab CiGoogle GeminiHadoopJenkinsKafkaKubernetesMongoDBOpenai GptOracleOwasp Top 10PostgresPytestPython 3.XPyTorchReactRedisRestful ApisScikit-LearnSQLSQL ServerTensorFlowUnittestUnixVue
8 Days AgoSaved
Hybrid
Minneapolis, MN, USA
115K-145K Annually
Senior level
115K-145K Annually
Senior level
Consulting • Design
Design and build enterprise web applications using Python backends and React front ends. Develop and consume APIs and microservices, apply cloud and DevOps practices (CI/CD, containers), collaborate with customers and cross-functional teams, and continuously learn and improve using AI-assisted development tools.
Top Skills: AWSAzureChatgptCi/CdClaudeDevOpsGCPGithub CopilotMicroservicesPythonReactRestful Apis
Reposted 8 Days AgoSaved
In-Office
Bellevue, WA, USA
Senior level
Senior level
Artificial Intelligence • Machine Learning • Software
Develop large-scale data analytic applications using Python or R. Familiarity with C#, .NET, and SQL is advantageous. Requires strong problem-solving skills.
Top Skills: .NetC#PythonRSQL
Reposted 8 Days AgoSaved
In-Office
Bethesda, MD, USA
5-5 Annually
Senior level
5-5 Annually
Senior level
Information Technology • Machine Learning • Consulting
Develop and maintain bioinformatics software systems, collaborate with scientists, and implement efficient algorithms for data processing.
Top Skills: BashC++Ci/CdCloud TechnologiesCshDockerGitJavaScriptLinuxMongoDBMs Sql ServerNoSQLPerlPython
Reposted 8 Days AgoSaved
Remote
United States
Senior level
Senior level
Information Technology • Consulting
Design and build applications using Python, manage component design, optimize performance, and collaborate with clients on innovative products.
Top Skills: Ai ToolsCi/CdGitGoKubernetesPythonReact
Reposted 8 Days AgoSaved
In-Office
Linthicum Heights, MD, USA
170K-260K Annually
Senior level
170K-260K Annually
Senior level
Big Data • Cloud • Security • Software • Analytics
The Senior Python Software Engineer at GliaCell is responsible for developing and supporting critical software solutions for U.S. Government clients, utilizing Python and various technologies in the cybersecurity domain.
Top Skills: AnsibleAWSDockerElasticsearchGitlab Ci/CdGrafanaKubernetesPythonSplunk
9 Days AgoSaved
In-Office
Rutherford, NJ, USA
121K-182K Annually
Senior level
121K-182K Annually
Senior level
Fintech • Financial Services
Design, build, and maintain scalable, enterprise-grade data pipelines, microservices, and AI agents using Python, PySpark, Databricks, Kafka, and cloud-native infrastructure. Develop and deploy agentic GEN AI solutions (Google ADK, LLMs), integrate models via MCP, implement data federation and Data Mesh patterns (Starburst), automate CI/CD for containerized services (OpenShift/Kubernetes), ensure data quality/security, and support risk/compliance in retail and wealth risk engineering.
Top Skills: AngularAWSAzureCi/CdClouderaDatabricksDevin.AiDockerFastapiGCPGithub CopilotGoogle AdkGoogle Flash 2.5JSONKafkaKubernetesMcpMicroservicesOpenshiftPysparkPythonReactScalaSpring BootSQLStarburstYaml
9 Days AgoSaved
In-Office
Rutherford, NJ, USA
121K-182K Annually
Senior level
121K-182K Annually
Senior level
Fintech • Financial Services
Design, build, and maintain scalable data pipelines and AI agent integrations using Python, PySpark, Databricks, Kafka, and microservices. Develop and deploy GenAI agents, data federation layers, and cloud-native CI/CD microservice integrations while ensuring data quality, security, and compliance.
Top Skills: AngularAWSAzureCi/CdClouderaDatabricksDevin.AiDockerFast ApiGCPGithub CopilotGoogle AdkGoogle Flash LlmsJSONKafkaKubernetesMcpMicroservicesOpenshiftPysparkPythonReact JsScalaSpring BootSQLStarburstYaml
9 Days AgoSaved
In-Office
2 Locations
131K-213K Annually
Senior level
131K-213K Annually
Senior level
Fintech • Payments
Designs, implements, tests, delivers, and operates backend solutions across the SDLC. Advises management, mentors junior engineers, makes technical decisions, and applies best practices. Works with Python frameworks (Django/Flask), web services/SOA, version control, databases, messaging systems, cloud/IaC, CI/CD, automated testing, and observability to build scalable payment platform features.
Top Skills: Automated TestingAWSAzureCi/CdDjangoEvent-Driven ArchitectureFlaskGCPGitKafkaNoSQLObservabilityPulsarPythonRabbitMQRedisService-Oriented ArchitectureSnsSQLSqsTerraform
Reposted 9 Days AgoSaved
In-Office
Palo Alto, CA, USA
Senior level
Senior level
Artificial Intelligence • Information Technology • Cybersecurity • Defense
Lead the design, development, and deployment of scalable applications for an AI platform, while mentoring junior developers and optimizing system performance.
Top Skills: Api DevelopmentAzureAzure Cosmos DbDatabase DesignGitLinuxMongoDBPython
All Filters
JobType
New Jobs
Job Category
Experience
Industry
Company Name
Company Size

Sign up now Access later

Create Free Account