Top Senior Python Jobs

Design, develop, test, debug, and deploy Python applications, REST APIs, microservices, and enterprise systems. Collaborate with architects, developers, and clients to deliver technical solutions, conduct code reviews, create reusable components, and integrate AI/ML technologies. Work in a client-facing consulting environment using modern software development practices, cloud platforms, databases, and version control.

Designs, develops, tests, deploys, and maintains Python-based applications, REST APIs, microservices, and enterprise systems. Collaborates with architects, developers, and clients to deliver technical solutions, participates in code reviews, builds reusable components, integrates AI and generative AI services, and follows modern software development practices in a consulting environment.

Design, develop, test, deploy, and maintain Python applications, REST APIs, microservices, and enterprise systems. Collaborate with architects, designers, developers, and clients to deliver technical solutions. Integrate AI models and services, contribute reusable components, participate in code reviews, troubleshoot software, and follow modern development practices. The role requires client-facing consulting, cloud, database, software lifecycle, and AI/ML experience, with preferred exposure to LLM platforms, RAG, vector databases, data engineering, containers, and DevOps.

Build and maintain complex backend APIs and system integrations using Python and TypeScript. The role requires 10+ years of backend engineering experience and collaboration with a U.S.-based team for at least 2–4 overlapping hours. Dental practice management system or healthcare integration experience is strongly preferred. Experience with GraphQL, Hasura, PostgreSQL, GCP, or AWS is valuable.

Build and maintain internal Python platform libraries and tooling to improve developer experience. Drive runtime, dependency, testing, delivery, monitoring, and performance optimization for Python services (including GPU-enabled workloads). Collaborate cross-functionally to define an opinionated SDLC, support on-call rotations, and balance modern practices with risk-aware change. Enable scalable, low-latency distributed systems and provide AI/ML-facing platform capabilities.

The Senior Software Engineer will design, develop, and maintain software applications using Python, C#, C++, and Linux, while collaborating with cross-functional teams to optimize performance and user experience.

Design and build full-stack applications that expose AI/ML insights. Develop backend services in Python, RESTful APIs, and containerized microservices. Build high-performance front-end interfaces with React/Vue/Angular. Implement cloud-native solutions on Google Cloud or Azure, manage relational and NoSQL databases, apply testing and CI/CD, and participate in Agile development and architecture sessions.

The Senior Python Engineer will design scalable software solutions, lead architectural discussions, collaborate with teams, and improve applications' performance.

Design, develop, deploy, and support scalable backend web applications and REST APIs using Python/Django. Build relational schemas and optimize PostgreSQL, create enterprise integrations (Dynamics AX, Salesforce, OneStream, Workday), troubleshoot production issues, perform code reviews and testing, and partner with stakeholders to modernize applications and automation (including React/TypeScript front-ends).

Design, build, and maintain large-scale, high-availability Python applications and data-intensive services. Troubleshoot production issues, perform system design, automated testing, and operational support. Collaborate with product, data, and infrastructure teams to deliver secure, performant solutions and improve engineering practices.

Alaffia Health seeks a Senior Python Engineer to develop AI-driven medical billing applications, focusing on backend API development and data processing. Responsibilities include collaborating across teams, improving observability practices, and ensuring successful project delivery.

Senior Python engineer responsible for designing, building, and operating high-performance, scalable distributed services for Quantitative Investment Strategies. Work includes architecture, coding, testing, CI/CD, performance optimization, incident analysis, and close collaboration with front office, quants, trading, and risk. Mentor junior engineers and lead platform modernization efforts.

Lead backend engineer responsible for designing, building, and operating cloud-native, event-driven services in AWS. Deliver high-quality, tested code, improve reliability and performance, contribute to observability, collaborate across product and infrastructure teams, and mentor peers while co-owning core services.

The Principal Python Backend Engineer will design and build high-performance backend systems for AI/ML services, focus on clean code, maintainability, and automation, while leading teams through a collaborative and innovative approach.

Design, develop, and maintain scalable Python applications; collaborate with cross-functional teams to deliver features; ensure performance and quality; identify and fix bugs; maintain code quality and automation; lead and mentor team members using agile practices.

Senior iOS developer responsible for implementing native iOS features, improving user experience, participating in agile squads, conducting code reviews, troubleshooting customer issues, and helping modernize backend services on AWS. Collaborates with product and UI teams and documents technical knowledge while following best practices.

Design, build, test, and maintain secure, scalable cloud-native full-stack applications for CBP. Develop backend services (Python, Java, Spring Boot), modern Angular frontends, RESTful APIs, and containerized microservices on AWS. Participate in Agile ceremonies, perform code reviews, mentor junior developers, optimize performance, and support SDLC activities to modernize enterprise systems and deliver high-quality software.

Design, build, test, and maintain backend applications using FastAPI and SQLAlchemy. Implement database schemas, integrate front-end components, optimize for performance and scalability, debug issues, participate in code reviews, and collaborate on feature design. Maintain clean, testable code and stay current with best practices.

Develop Python microservices and APIs using FastAPI; implement data validation with Pydantic; enforce linting (flake8); integrate with MongoDB via PyMongo; connect to GraphQL and graph databases; install and configure Neo4j.

Lead a small team to design, implement, and test Python-based simulation software modeling satellite and ground-station networks. Develop algorithms to characterize atmospheric impacts and optimize communications traffic, build deployment pipelines, transfer tools to classified environments, mentor junior developers, collaborate with network specialists, and deliver technical updates to government customers.

Design, build, and operate backend services for vehicle-transport workflows. Own architecture, REST APIs, async/background processing, partner integrations, performance tuning, observability, on-call incident response, mentoring, and cross-functional API/product collaboration to deliver reliable, scalable services.

Develop, enhance, and support Python-based enterprise applications and automation on the Quartz platform. Build APIs, data-processing solutions, scheduled workflows, and automated test suites. Collaborate with business, architects, and operations to deliver scalable, resilient, and maintainable solutions, mentor engineers, automate releases, and contribute to platform modernization and cloud-native adoption.

Senior management role leading one or more applications development teams to design, build, and maintain Java/React applications and micro-frontends. Provide technical oversight, review solutions, manage staff and budgets, ensure compliance with policies, and drive delivery using containerization and orchestration (Docker/Kubernetes).

Lead and implement enterprise-grade Python systems, design scalable architectures, ensure production reliability, tune relational databases, collaborate with product/data/infrastructure teams, drive SDLC best practices, debug complex issues, and mentor engineering practices across projects.

The Senior Developer is responsible for designing and developing solutions for transforming data files, generating documents, and ensuring optimal process efficiency. Key tasks include managing project requirements, providing technical designs, and maintaining documentation.