Top Pittsburgh, PA Startups (10,000+)

At eClinical Solutions, our goal is to leverage technology to accelerate clinical research and bring life-changing therapies to patients faster. Our industry-leading elluminate® clinical data platform is used by top life sciences companies worldwide to regain control of their data and provide meaningful analytical insights.

Tune into the innovation, collaboration and culture that our team members bring to the office every day. We want you to be a part of our journey to build the next generation of technology that transforms the way the world communicates. Our team members are the key to our history of groundbreaking innovation and our continued progress. If you bring...

At Vibes, our premier mobile messaging platform helps world-class brands intelligently automate and optimize their mobile marketing outcomes through the power of SMS, MMS, RCS and Mobile Wallet. Industry leaders like Chipotle, Kohl’s, Polo Ralph Lauren, The Children's Place, KFC, Ulta Beauty, and others use Vibes to grow their customer relationships with relevant, high-volume mobile messaging and mobile wallet marketing on...

We are a mobility company that innovates like a start-up and thinks like a technology company. This helps us anticipate change in one of the most complex industries in the world and respond quickly. We depend on a team of 171,000 dynamic, entrepreneurial-minded employees in an environment where great ideas flourish. Our presence spans 343 manufacturing operations and 88 product...

Founded in 2014, Opendoor’s mission is to empower everyone with the freedom to move. We believe the traditional real estate process is broken and confusing. It often comes with unexpected costs, the added burden of coordinating multiple third parties and the uncertainty of a transaction falling through. Our goal is simple: build a digital, end-to-end customer experience that makes buying...

Lob provides the building blocks for developers to automate the offline world. We provide insight into deliverability with piece-by-piece tracing and utilize our proprietary Print Delivery Network to streamline production across fully redundant nodes all over the country. Our mission is to make mail intelligent, by providing a product that is fast, personalized, and sustainable!

With over 1,400 team members across multiple companies, dedicated to improving the lives of people and their pets, we create best-in-class products that bring health and happiness. Our creative content educates the world on making smarter health choices, while the brands we own generate over $1 billion of revenue annually. From brand ideation to ad creation to product fulfillment, the...

From film, television, news, theme parks, interactive media, and streaming, our people are at the center of it all. ​Here, we solve complex and business-critical problems. That’s why we’re looking for people to help us continue our evolution, imagining and delivering the most innovative and disruptive products and services through the latest tech advancements in the industry. ​ Here you...

Supernova is the technology leader in securities-based lending ("SBL") solutions that connect and empower the entire financial ecosystem. We offer the world’s first and only cloud-based, fully-customizable, end-to-end software solution to automate securities-based lending from origination through the life of the loan.

Upside is a technology company that increases the financial power of people and businesses in the real world. Our technology has helped millions of people get more purchasing power on the things they need, and tens of thousands of brick-and-mortar businesses earn measurable profit. Billions of dollars in commerce run through the Upside platform every year, and that value goes...

The database market is big. How big? Well, according to IDC, it’ll reach $153 billion by 2027. And MongoDB is at the forefront of that innovation with thousands of customers across the globe. We empower developers and businesses to build and deploy the applications they want, wherever they want.

Founded in 2001, Adage Tech is a web design and development firm combines strategic thinking with a passion for technology to advance our client's purpose. We bring together a diverse team of creative and technical professionals who partner with our clients to create their digital strategy and build applications to connect with their audiences.

Datadog (NASDAQ: DDOG) is a global SaaS business, delivering a rare combination of growth and profitability. We are on a mission to break down silos and solve complexity in the cloud age by enabling digital transformation, cloud migration, and infrastructure monitoring of our customers' entire technology stacks. Built by engineers, for engineers, Datadog is used by organizations of all sizes...

Named among the World’s Most Admired Companies™ by Fortune and recognized in the Fortune 100 Best Companies to Work For® list in 2025, MetLife is leading the global transformation of an industry we’ve defined for more than 155 years. At MetLife, every innovation and line of code is a lifeline for our customers and their families—from victims of natural disasters...

Fusion Risk Management is recognized as the most innovative and fastest growing provider of cloud-based enterprise software for business continuity risk management, IT disaster recovery and crisis management. Fusion is transforming the industry and has been named a leader in Gartner's Magic Quadrant for Business Continuity Management software.

Red 6 is an innovative Augmented Reality (AR) technology startup leading the way in synthetic air combat training. Our primary technology, supporting our ATARS product, enables pilots to simulate the cognitive challenges of flying while accessing realistic, scalable training in dynamic outdoor environments

Founded in 2013 in Hawaii and acquired by Booking Holdings in 2018, FareHarbor creates powerful tools that enable our clients (think boat rentals, museums, food tours, events and more!) to operate and grow. With over 20,000 clients across 90+ countries—we’re the largest in our industry and shaping the future of travel, together. Our team is an ‘Ohana of 900+...

Founded in 2010, Doximity is the leading digital platform for U.S. medical professionals. Our network members include over 80% of U.S. physicians across all states and every medical specialty. Our mission is to help every physician be more productive and provide better care for their patients. We are physicians-first, putting technology to work for doctors instead of the other way around....

Current is a U.S. based consumer fintech and payments platform with over four million members and a mission to improve financial outcomes. It provides mobile banking services that give its members access to opportunities to improve their financial lives, such as paychecks up to two days early, up to 4% APY, fee-free overdraft, money management tools and insights, fee-free ATMs,...

Founded in 2011, Zapier is the world’s most connected AI Orchestration platform. By connecting over 8,000 of the most popular work apps, Zapier empowers its users to make the most of the tools they already use—and to focus on what matters most and ultimately, make automation work for everyone. With teammates spanning 40+ countries around the world, we're fully remote, forever.