Top Senior Machine Learning Jobs in Washington, DC

Leads AI presales strategy, customer advisory, technical solution architecture, and team development. Translates business needs into AI use cases, prototypes, business cases, roadmaps, and repeatable offerings. Partners with sales, engineering, consultants, and technology vendors to support complex pursuits, executive briefings, demonstrations, proofs of concept, and AI business growth. Promotes responsible AI governance, tracks pipeline performance, develops thought leadership, and remains hands-on in high-impact customer engagements.

Drive new enterprise revenue and customer expansion by selling AI-powered SaaS solutions. Manage complex 6–12 month sales cycles, build executive relationships, develop value propositions, maintain pipeline accuracy, lead virtual account teams, and close high-value deals. Translate technical AI capabilities into measurable business outcomes, guide customer adoption, collaborate with marketing, product, and customer success teams, and exceed quarterly pipeline and revenue targets.

Supports defense IT portfolio modernization through requirements analysis, business process reengineering, enterprise and application architecture, systems mapping, technology evaluations, application consolidation, and technical gap analysis. Evaluates emerging AI and machine learning capabilities, commercial and government software, and program management tools. Provides technical support for IT governance, security reviews, audit compliance, BCAC processes, Oracle EBS, and phased modernization strategies.

Architect and prototype scalable solutions for Twilio’s emerging technologies experimentation team. Lead AI, machine learning, and LLM-driven initiatives; guide technical direction; mentor engineers across the US and India; align prototypes with business goals; and ensure enterprise architecture, scalability, extensibility, and production readiness. The role requires extensive architecture or principal engineering experience, cloud expertise across AWS and Azure, full-stack development knowledge, database expertise, and strong technical leadership.

Lead the development of machine learning systems for Cedar Pay's Personalization Engine, manage ML engineers, and ensure ML model effectiveness.

Build rigorous ROI analyses, value models, and business cases that translate AI ranking performance into revenue, margin, and cost-to-serve outcomes. Present analyses to CFOs, procurement teams, and other economic buyers; support sales pursuits; create reusable value-selling frameworks; tailor models to customer economics; and collaborate with product, data science, and customer teams to validate benchmarks and deployment results.

Own the full Global System Integrator partner lifecycle, including sourcing, agreements, joint go-to-market motions, enablement, delivery planning, and performance optimization. Build relationships across major GSIs such as Accenture, Deloitte, Bain, BCG, Slalom, and IBM. Collaborate with sales, product, and engineering teams to generate partner-sourced and influenced pipeline and revenue. Develop the GSI strategy, playbook, and operating processes for Sequen’s growing AI business.

Build and operate production machine learning systems for Airbnb Payments, including LLM agents, real-time fraud detection, anomaly detection, personalization, and checkout optimization. Design, train, deploy, monitor, and continuously improve batch and streaming AI applications at global scale. Partner with product, engineering, operations, and data science teams, establish model governance and testing standards, and mentor engineers.

Drive go-to-market reporting, business intelligence, forecasting, dashboard development, and ad hoc analysis. The role standardizes forecasting processes, maintains analytical documentation, automates reporting and data pipelines using AI-assisted tools, and delivers actionable insights to Sales, Marketing, Engineering, Finance, and executive stakeholders.

Build and lead the organization-wide adoption of generative AI, agentic systems, and AI-assisted development. Design production automation agents, evaluate coding tools, modernize rules-based workflows with ML, and establish responsible AI guardrails. Partner with engineering, product, data, and clinical teams to identify high-impact opportunities, own the enablement roadmap, measure outcomes, and drive adoption through working software, documentation, and hands-on collaboration.

Leads business analysis for AI and automation initiatives, identifying adoption opportunities, developing business cases, gathering requirements, and aligning business needs with technical solutions. The role facilitates stakeholder workshops, supports solution design, testing, deployment, change management, governance, and benefits realization. It also advises executives, monitors outcomes, promotes business analysis standards, and mentors junior analysts.

Leads operational oversight, performance analysis, governance, and continuous improvement for AI-powered products and services. Develops performance frameworks, executive dashboards, business insights, risk and compliance reporting, and scalable AI operating models. Partners with AI engineers, product teams, and business leaders to optimize workflows, support automation, manage operational risks, and drive cross-functional operational excellence.

Leads the strategy, roadmap, development, launch, and optimization of AI-powered products. Defines product vision, requirements, priorities, success metrics, and adoption goals while coordinating engineering, AI, business, executive, and customer stakeholders. Evaluates emerging AI capabilities, supports responsible AI governance, manages product performance, and drives continuous improvement aligned with business objectives.

Leads analytical and scientific strategy for Fetch’s Play and Rewarded Apps businesses. Develops predictive and machine learning models, experimentation frameworks, causal analyses, feature pipelines, and measurement systems using Python and SQL. Partners with Product, Marketing, Engineering, and business leaders to improve monetization, engagement, retention, personalization, and marketplace outcomes. Translates complex findings into strategic recommendations, mentors data scientists and analysts, and establishes analytical best practices.

Own the full machine learning lifecycle for search ranking and retrieval, including model training, deployment, serving, feature pipelines, evaluation frameworks, hybrid lexical-vector retrieval, large-scale embedding inference, query understanding, and permissions-aware multi-tenant search. Collaborate with infrastructure, AI, and backend teams to improve search relevance across ClickUp’s platform.

Senior backend engineer responsible for setting technical direction, designing scalable distributed systems, building customer-facing web applications, mentoring engineers, and applying machine learning to large-scale healthcare data. The role requires Java, Scala, or Rust expertise, cloud systems experience, technical design leadership, cross-functional collaboration, and adoption of agentic engineering practices.

Build and operate production retrieval-augmented generation systems, including embeddings, vector retrieval, grounded language-model generation, citation validation, prompt and schema design, model packaging, serving, rollback, and telemetry. Develop bounded model assistance for narrative extraction with provenance and rule-context tracking. Maintain resilient serving paths in secure government cloud environments, including restricted or air-gapped deployments.

Provide commercial legal support for enterprise cloud, SaaS, and infrastructure transactions. Draft, negotiate, and advise on contracts (SaaS, IaaS, software licensing, DPA), counsel sales and cross-functional teams on legal/privacy/commercial risk, manage concurrent deals, improve templates and processes, and coordinate outside counsel to enable scalable, business-focused legal support for growth.

Provides strategic and hands-on biostatistical leadership across pharmaceutical discovery, translational, biomarker, and early research programs. Designs studies, analyzes complex biological datasets, develops advanced statistical methods and reproducible R workflows, and translates evidence into portfolio decisions. The role collaborates with quantitative and scientific functions, supports publications and external partnerships, mentors statisticians, and advances data-driven analytical practices.

Conducts data analytics, engineering, mining, statistical analysis, predictive modeling, and intelligence-focused data visualization. Designs and optimizes data architectures, storage, access, integration, throughput, and query performance. Builds AI automation tools and prediction systems from disparate data sources, collaborates with intelligence community members, communicates complex findings, and develops concise defense intelligence products. Requires active TS/SCI clearance, U.S. citizenship, and ability to obtain a counterintelligence polygraph.

Own AgentSee’s sales and go-to-market strategy as the first dedicated sales leader. Personally close early enterprise opportunities, refine the ideal customer profile, positioning, pricing, packaging, and sales process, and translate AI capabilities into measurable business value. Build repeatable sales operations and playbooks, provide market feedback to Product and Engineering, and eventually hire and lead the AgentSee sales organization.

Leads the design, development, deployment, and operation of scalable machine learning solutions and high-performance microservices. Builds real-time inference systems using Triton and TensorRT, guides distributed cloud architectures, participates hands-on in coding and reviews, and mentors engineers. Drives technical strategy, operational excellence, system resilience, and business-wide innovation across generative AI, graph machine learning, and big data initiatives.

Develop and deploy NLP and machine learning models for classification, sentiment analysis, entity extraction, information retrieval, and user intent detection across large-scale legal, financial, news, and business datasets. Design scalable data science pipelines, evaluate modern AI algorithms and tools, translate business needs into technical solutions, and collaborate with product and engineering teams. Mentor junior scientists and contribute to model deployment, monitoring, maintenance, and development best practices.

Lead exploration and application of large language models and generative AI for enterprise contact-center automation. Translate research into high-performing, deployable ML systems; contribute across experimentation, implementation, and deployment; collaborate with engineering and product teams; optimize performance; and help shape team strategy, innovation, and professional growth.

Lead exploration and application of large language models and generative AI, translate research into deployable ML systems, and guide strategic direction. Develop solutions across experimentation, implementation, and deployment while collaborating with engineering and product teams to optimize performance and customer outcomes in contact center automation.