Top Senior Machine Learning Jobs in Washington, DC

Lead production-grade ML systems: build data pipelines, training and evaluation workflows, and scalable GPU inference. Fine-tune and adapt large models (LoRA, QLoRA, SFT, DPO, distillation), optimize deployments for latency/cost/reliability, and collaborate with product and engineering to ship robust, observable model-driven features.

Lead the end-to-end ML execution: build and operate data pipelines, training and evaluation systems, and scalable inference. Fine-tune and optimize large models (LoRA/QLoRA/SFT/DPO/distillation), ensure GPU efficiency, monitor production quality, collaborate with product and application engineering, and rapidly ship reliable, safe ML solutions that translate research into production.

Manage post-sales relationships with a portfolio of customers, primarily financial institutions, to drive adoption and business outcomes from BioCatch’s behavioral biometric solution. Responsibilities include strategic consulting, project coordination, risk and escalation management, customer presentations, quarterly business reviews, roadmap feedback, stakeholder communication, team coaching, statements of work, and identifying expansion opportunities with account managers.

Lead design and implementation of Headway's insurance systems (eligibility, pricing, matching, claims). Build data-intensive, ML-powered platforms and automation, mentor engineers, write high-impact code, and improve accuracy and reliability across state and payer complexity to scale insurance-covered therapy.

Drive enterprise adoption of AI services-led solutions by developing sales strategies, building pipelines, advising C-level stakeholders, designing tailored engagements, presenting solutions, negotiating contracts, and closing complex professional or managed services deals. Collaborate with consulting, delivery, presales, engineering, marketing, and customer success teams while contributing market insights, sales enablement, and thought leadership.

Design, productionize, and scale machine learning and optimization models, pipelines, libraries, and deployment platforms. Partner with data scientists, engineers, product managers, and business stakeholders to deliver ML capabilities, personalization systems, and reusable end-to-end workflows. Establish ML engineering best practices, troubleshoot data pipelines, mentor junior professionals, and help define BetterHelp’s ML platform strategy.

Own customer outcomes from discovery through production deployment. Build decision systems using ontologies, reasoning, graph analytics, optimization, and machine learning over enterprise data. Write Python, SQL, and PyRel; debug unfamiliar systems; tune performance; harden deployments; document reusable solutions; and upstream platform improvements. Lead technical workshops and proofs of concept while partnering closely with customers, Product, and Engineering.

Drive new-logo sales and revenue growth for Wonderlic’s talent assessment and employee development solutions. Identify and prospect target clients, build relationships with HR and recruiting decision-makers, manage opportunities through the full sales cycle, close new business, and transition customers to Customer Success. Maintain expertise in products, market trends, and competitive conditions while providing strategic insights. The role requires B2B SaaS and HR technology sales experience, quota achievement, pipeline generation, and experience selling to SMB, mid-market, and enterprise buyers.

Own strategic partnerships with CPG customers, driving measurable outcomes, platform adoption, user expansion, and retention. Analyze usage data and business context to identify risks and opportunities, develop success plans, lead executive and operational relationships, and advocate for customers internally. Collaborate with product, sales, marketing, and support teams while contributing to repeatable playbooks, thought leadership, and customer best practices.

Conduct applied research on scalable optimization and resource-allocation algorithms for large communication networks. Apply machine learning, reinforcement learning, integer optimization, graph-based methods, and metaheuristics to improve solution quality and efficiency. Collaborate with software engineers to integrate algorithms into production aerospace networking systems, evaluate performance at realistic scale, publish research, support patent applications, and document novel methods.

Design and productionize machine learning, deep learning, LLM, personalization, recommendation, search, and retrieval systems. Collaborate with product, engineering, and analytics teams to deploy AI solutions that improve customer experiences, business growth, and operational efficiency. The role requires driving projects from ideation through deployment and delivering measurable business impact in a fast-moving fintech environment.

Lead data science for defense clients: perform data engineering, mining, exploratory/predictive/statistical analysis; build ML/AI tools (recommendation engines, automated scoring); manage large, disparate data sources using R/Python/SQL; create visualizations in Power BI/Tableau; support Multi-INT analytics and provide senior-level analytic products for the defense cover program.

Serve as the primary technical pre-sales lead for gaming and sportsbook clients: run discovery, design identity and fraud workflows, lead POCs/backtests, build demos, and translate model and integration details for executive stakeholders. Collaborate with Sales, Data Science, Product, Engineering, and Customer Success to accelerate deals and ensure smooth handoffs to post-sales teams.

Develop and optimize machine learning and statistical models for fraud detection and anti-money laundering. Analyze large datasets to identify fraudulent patterns, build scalable data pipelines and features, evaluate model performance, and collaborate with engineering, product, and operations teams. Communicate insights to technical and non-technical stakeholders while maintaining data privacy and security compliance. The role offers significant ownership in building Oscilar’s early machine learning stack within a remote-first startup.

Own LanceDB’s product direction by shaping the roadmap with technical leadership, researching users and competitors, gathering continuous user insight, and driving cross-functional prioritization. The role partners closely with engineering as a technically respected peer, defines product changes for AI and data-platform users, uses metrics and experiments to guide decisions, and operates with high ownership in an ambiguous environment.

Advise enterprise clients on AI and data strategies, transformation roadmaps, operating models, governance, privacy, technology rationalization, and business cases. Lead discovery workshops, executive engagements, and art-of-the-possible sessions; prioritize use cases and connect technical recommendations to business outcomes. Build the advisory practice, develop offerings, manage multidisciplinary teams, mentor staff, strengthen client and partner relationships, and support successful distributed project delivery.

Tune AML and fraud detection models using customers’ live transaction data. Investigate missed cases, alert quality, pattern drift, and false positives; validate changes through backtesting and sample review; document regulatory rationale; and present model performance and business value to compliance, risk, and data science stakeholders. Partner with customer teams on account strategy and relay customer-specific or systemic findings to product and model functions.

Drive net-new enterprise customer acquisition from lead generation through contract closure. Build C-level relationships, develop account strategies, manage CRM pipelines and forecasts, negotiate complex contracts, and close large AI, machine learning, and data talent engagements. Partner with marketing, customer success, and talent teams to deliver customer outcomes and expand Factored AI’s enterprise footprint.

Own the production lifecycle for machine learning and LLM-backed systems, including training and post-training pipelines, inference serving, model releases, monitoring, retrieval infrastructure, and cost and latency optimization. Partner with AI researchers and engineering teams to move prototypes into reliable production capabilities across customer tenants. Develop ETL and GraphQL features, enforce tenant isolation, and support deployments in regulated or customer-controlled environments.

Designs, deploys, and scales production AI agents and agentic workflows within enterprise Java and Spring applications. Establishes evaluation, monitoring, guardrail, safety, testing, observability, deployment, and operational standards for LLM systems. Leads architectural decisions across AI services and microservices, productionizes models, evaluates emerging technologies, mentors engineers, and influences technical strategy across teams.

Build and operate scalable ML infrastructure and platform capabilities across cloud and on-premises environments. Develop Python-based developer tooling, services, and production systems supporting experimentation, distributed training, model deployment, and operations. Lead complex initiatives from architecture through rollout, improve reliability and developer productivity, and partner with ML and infrastructure teams. The role emphasizes Kubernetes, AWS, distributed compute, GPU-intensive workloads, observability, and production excellence.

Leads enterprise IAM strategy for public cloud, SaaS, generative AI, machine learning, and agentic AI environments. Defines governance, standards, controls, roadmaps, and identity-security patterns; assesses cloud and vendor solutions; evaluates human and non-human identity risks; and advises on least privilege, authorization, secrets, and entitlement governance. Partners with technology, risk, compliance, audit, and executive stakeholders to identify gaps, guide modernization, and communicate strategic recommendations.

You will tackle AI challenges, develop scalable software and collaborate with teams to enhance healthcare navigation using AI solutions.

Partner with functional leaders to translate business strategy into people strategy. Own org design, performance management, compensation, talent development, engagement, and retention. Provide coaching on career pathing, change management, and sensitive employee issues. Use people data to generate insights and recommendations, build compliant HR policies, manage global employee relations, and collaborate with People Team COEs to deliver cohesive people programs at scale.

Serve as second-in-command for Coinbase Derivatives' Market Regulation Department, leading day-to-day regulatory compliance, managing exams and audits, advising on CFTC Core Principles, reviewing surveillance escalations and enforcement actions, and coordinating cross-functional regulatory workstreams to ensure the DCM meets obligations and resolves findings timely.