Top Washington, DC Machine Learning Companies (60)

GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is using the power of high-intensity sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop and commercialize pioneering products.

At Shield AI, you won't wait years to see your work reach the field. You'll build hardware and software that operates in the real world right now, in the hands of the people who depend on it. Hivemind, our AI pilot, has been flying since 2018. It has flown more than 30 platforms, including an F-16, and it now sits under...

We bring together one of the world’s largest libraries of multimodal clinical and molecular data with a robust suite of AI tools to help physicians personalize care in real time, connect patients with therapies and clinical trials, and enable partners to accelerate discovery and development of new treatments. With ~8 million de-identified research records and 350+ petabytes of data, Tempus partners...

STR makes the world a safer place by developing technology and applying it to solve emerging national security challenges.

MORSE is a specially selected team of scientists, engineers, and software developers who use asymmetric and unconventional approaches to deploy practical solutions that solve difficult multi-disciplinary problems faced by the US National Security Ecosystem.

Space was once the quietest place in the universe. Now, it's crowded, contested, and confrontational.  We are True Anomaly: the only defense company focused exclusively on space defense. Founded in 2022 by ex-U.S. Space Force members, True Anomaly designs and builds advanced systems for space superiority: agile and powerful spacecraft platforms, mission software engineered for unmatched command and control, and payloads...

ASI is a dual-use software company that deploys predictive AI to the world's most complex operating environments. Backed by leading investors–including Andreessen Horowitz, Renegade Partners, and Spark Capital–we actively manage over 40% of all US air traffic across both public and private sector air operations. Partnering with major airlines like United and Alaska, we optimize thousands of flights daily, delivering...

Altana powers agentic trade workflows and public-private collaboration across product value chains — the source of truth for where products come from. With Altana, businesses can prove compliance before goods ship and build more efficient, resilient, and secure supply chains. Logistics providers can automate the full brokerage workflow, and governments can promote economic security, manage borders, and enable the flow...

Upside is a technology company that increases the financial power of people and businesses in the real world. Our technology has helped millions of people get more purchasing power on the things they need, and tens of thousands of brick-and-mortar businesses earn measurable profit. Billions of dollars in commerce run through the Upside platform every year, and that value goes...

Vannevar combines Silicon Valley innovation with former special operators to build AI for real-world national security outcomes. Since our founding in 2019, Vannevar has deployed its technology across 125 missions, safeguarding our service members and improving our country's deterrence. We believe our military service members and intelligence officers deserve access to the best technology American innovation can offer, and we are...

We contribute to human progress by empowering people to express themselves, live in the moment, learn about the world, and have fun together.

Optum, part of the UnitedHealth Group family of businesses, is a global organization that delivers care, aided by technology to help millions of people live healthier lives. The work you do with our team will directly improve health outcomes by connecting people with the care, pharmacy benefits, data and resources they need to feel their best. Here, you will find...

Bellagent is an enterprise-level AI agent platform built to automate everyday business operations with zero-touch integrations that connect instantly to more than 1,300 applications. Launched in 2025 by Proactifi Inc., and headquartered in Chicago, the platform is built for practicality with industry-leading compliance and security standards, enabling organizations to deploy AI agents without friction from day one. Bellagent’s mission to...

Pendulum gives you advanced social listening with intelligence that moves you forward. Protect and grow your brand reputation with insights from TikTok, YouTube, Instagram, BitChute, Snapchat and 20 other platforms.

Epirus is a high-growth technology company developing solid-state, software-defined directed energy systems that enable unprecedented counter-electronics effects and power management solutions to optimize power efficiency in defense and commercial applications. With a constant emphasis on innovation, we are redefining the future of power to bring tomorrow’s capabilities to life, today.   To deliver on our mission, we are always looking for...

Procurement Sciences is redefining how government contractors find, win, and deliver with AI. They provide an AI-driven platform to automate and optimize proposal, capture, and business development processes for government contractors.

Civis Analytics helps leading businesses, nonprofits, and government agencies use data to identify, attract, and engage customers, constituents, and citizens. We use proprietary data, technology and advisory services, and an interdisciplinary team of data scientists, developers, and survey science experts, Civis helps organizations stop guessing.

Safari AI, fka curbFlow, delivers cutting-edge Computer Vision AI solutions that empower enterprise clients to monitor and analyze their physical operations in real-time using their own camera systems. With the flexibility to seamlessly integrate with any modern IP camera, we can apply our wide range of algorithms to start gathering essential data for our clients within days. Our sophisticated data analytics...

Tria Federal (Tria) delivers digital services and technology solutions that support the health and safety of veterans, service members and civilians. For two decades, federal agencies have relied on Tria companies to help them complete their critical missions and modernize their systems, so that they can uphold their commitment to the American people. Today, our technology innovation group Tria Labs...

The space enterprise has been transformed by rapid change and growth. New vehicles for national security space, a more rapid launch cadence, proliferated satellite constellations, the pursuit of interplanetary exploration, and thriving commercial ventures are changing the nature of the space industry. The Aerospace Corporation (Aerospace) is a leading architect for U.S. space programs, shaping efforts to outpace threats to...