Top Washington, DC Machine Learning Companies (60)

GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is using the power of high-intensity sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop and commercialize pioneering products.

MORSE is a specially selected team of scientists, engineers, and software developers who use asymmetric and unconventional approaches to deploy practical solutions that solve difficult multi-disciplinary problems faced by the US National Security Ecosystem.

Upside is a technology company that increases the financial power of people and businesses in the real world. Our technology has helped millions of people get more purchasing power on the things they need, and tens of thousands of brick-and-mortar businesses earn measurable profit. Billions of dollars in commerce run through the Upside platform every year, and that value goes...

Altana powers agentic trade workflows and public-private collaboration across product value chains — the source of truth for where products come from. With Altana, businesses can prove compliance before goods ship and build more efficient, resilient, and secure supply chains. Logistics providers can automate the full brokerage workflow, and governments can promote economic security, manage borders, and enable the flow...

We bring together one of the world’s largest libraries of multimodal clinical and molecular data with a robust suite of AI tools to help physicians personalize care in real time, connect patients with therapies and clinical trials, and enable partners to accelerate discovery and development of new treatments. With ~8 million de-identified research records and 350+ petabytes of data, Tempus partners...

Optum, part of the UnitedHealth Group family of businesses, is a global organization that delivers care, aided by technology to help millions of people live healthier lives. The work you do with our team will directly improve health outcomes by connecting people with the care, pharmacy benefits, data and resources they need to feel their best. Here, you will find...

We contribute to human progress by empowering people to express themselves, live in the moment, learn about the world, and have fun together.

ASI is a dual-use software company that deploys predictive AI to the world's most complex operating environments. Backed by leading investors–including Andreessen Horowitz, Renegade Partners, and Spark Capital–we actively manage over 40% of all US air traffic across both public and private sector air operations. Partnering with major airlines like United and Alaska, we optimize thousands of flights daily, delivering...

Vannevar combines Silicon Valley innovation with former special operators to build AI for real-world national security outcomes. Since our founding in 2019, Vannevar has deployed its technology across 125 missions, safeguarding our service members and improving our country's deterrence. We believe our military service members and intelligence officers deserve access to the best technology American innovation can offer, and we are...

STR makes the world a safer place by developing technology and applying it to solve emerging national security challenges.

At Shield AI, you won't wait years to see your work reach the field. You'll build hardware and software that operates in the real world right now, in the hands of the people who depend on it. Hivemind, our AI pilot, has been flying since 2018. It has flown more than 30 platforms, including an F-16, and it now sits under...

Space was once the quietest place in the universe. Now, it's crowded, contested, and confrontational.  We are True Anomaly: the only defense company focused exclusively on space defense. Founded in 2022 by ex-U.S. Space Force members, True Anomaly designs and builds advanced systems for space superiority: agile and powerful spacecraft platforms, mission software engineered for unmatched command and control, and payloads...

Bellagent is an enterprise-level AI agent platform built to automate everyday business operations with zero-touch integrations that connect instantly to more than 1,300 applications. Launched in 2025 by Proactifi Inc., and headquartered in Chicago, the platform is built for practicality with industry-leading compliance and security standards, enabling organizations to deploy AI agents without friction from day one. Bellagent’s mission to...

Civis Analytics helps leading businesses, nonprofits, and government agencies use data to identify, attract, and engage customers, constituents, and citizens. We use proprietary data, technology and advisory services, and an interdisciplinary team of data scientists, developers, and survey science experts, Civis helps organizations stop guessing.

DNSFilter is redefining how organizations secure their largest threat vector: the Internet itself. DNSFilter is making the Internet safer and workplaces more productive by blocking threats at the DNS layer. DNSFilter resolves upwards of 130 billion daily queries. With 79% of attacks using Domain Name System (DNS), DNSFilter provides the world’s fastest protective DNS powered by AI, blocking threats an...

The space enterprise has been transformed by rapid change and growth. New vehicles for national security space, a more rapid launch cadence, proliferated satellite constellations, the pursuit of interplanetary exploration, and thriving commercial ventures are changing the nature of the space industry. The Aerospace Corporation (Aerospace) is a leading architect for U.S. space programs, shaping efforts to outpace threats to...

Headquartered in Boston with offices and 1000 employees around the world, Recorded Future works with over 1,800 businesses and government organizations across more than 75 countries to provide real-time, unbiased and actionable intelligence. Recorded Future is the world’s largest threat intelligence company. Recorded Future’s Intelligence Cloud provides end-to-end intelligence across adversaries, infrastructure, and targets. Indexing the internet across the open...

ENSCO, Inc., and its wholly owned subsidiaries, represent a more than $190+ million international technology enterprise with 750+ employees headquartered in the Washington, D.C., area. For more than 50 years, ENSCO has been providing leading-edge engineering, science and advanced technology solutions to governments and private industries worldwide. ENSCO operates in the aerospace, national security, and surface transportation sectors. ENSCO serves...

Pendulum gives you advanced social listening with intelligence that moves you forward. Protect and grow your brand reputation with insights from TikTok, YouTube, Instagram, BitChute, Snapchat and 20 other platforms.

Dataminr -- long recognized as one of the world’s leading artificial intelligence (AI) startups -- puts real-time AI and public data to work for our customers, generating relevant and actionable alerts for thousands of users working in more than 100 countries for hundreds of client organizations--spanning global corporations, public sector agencies, NGOs, and newsrooms. As 2020 taught us, the unexpected can...