Jobs at GRAIL

Field-based HEOR liaison responsible for communicating and refining health economic, outcomes, and real-world evidence to payers. Support AMCP dossiers, value frameworks, and payer-focused education; partner with Market Access, Medical Affairs, and Commercial teams; identify data gaps, inform research priorities, and represent evidence at regional and national meetings. Requires travel for external engagements and internal collaboration.

Develop and validate predictive models using population-scale genomic and NGS datasets to monitor and improve a multi-cancer classifier. Integrate genomics, DNA methylation, epidemiology, and statistics to identify performance trends, communicate findings cross-functionally, and build reproducible analysis pipelines to support clinical product deployment.

Perform advanced molecular diagnostic testing (including NGS) in a CLIA/CAP clinical laboratory, manage sample prep, run and troubleshoot instruments, verify and document results, support QC and validation activities, and contribute to workflow and regulatory compliance on 2nd shift.

Lead design, development, testing, and deployment of large-scale software systems. Define architecture and best practices, mentor engineers, collaborate with stakeholders, ensure regulatory and security compliance, and drive platform strategy and technical excellence.

Lead design and development of cloud-native full-stack and microservice systems for patient-facing and clinical data platforms. Provide technical leadership, drive cross-functional programs, improve engineering practices, and mentor engineers to deliver robust, scalable software.

Lead a team to develop, optimize, and troubleshoot NGS-based assays and platform workflows. Design and execute experiments, analyze results, identify root causes of performance issues, implement corrective actions, document findings, and collaborate cross-functionally while ensuring regulatory and quality compliance and mentoring direct reports.

The GRAIL Galleri Consultant will drive territory growth, engage healthcare providers, and execute sales strategies for the Galleri product, focusing on early cancer detection.

Support continuous improvement in sequencing-based lab operations by generating automated KPI reporting, performing statistical/process analyses (SPC/QC), executing Lean/Six Sigma/Kaizen projects, tracking operational issues, and collaborating across Operations, Engineering, Software, and Product teams to scale process improvements.

Lead continuous improvement for sequencing-based cancer screening operations: build dashboards and automated KPI reporting, perform statistical process control and data analysis, execute Lean/Six Sigma projects, conduct root-cause analyses and CAPAs, track and prioritize issues, and partner with cross-functional teams to pilot and scale process improvements in regulated lab settings.

Support continuous improvement across sequencing-based lab and operational workflows by automating KPI reporting, performing statistical and SPC analyses, executing Lean/Six Sigma/Kaizen initiatives, piloting process improvements, tracking issues, and collaborating with cross-functional teams to improve efficiency, quality, and scalability.

Lead operational excellence by developing dashboards, KPI reporting, SPC/QC monitoring, and Lean/Six Sigma programs. Drive continuous improvement, prioritize issues, and partner cross-functionally to scale lab and operational processes in a regulated NGS/diagnostics environment.

Lead on-site biorepository operations for ~1M specimens, managing receipt, storage, tracking, retrieval, vendor relationships, LIMS/inventory systems, regulatory compliance (CAP/CLIA/ISO), staff leadership, accreditation activities, and operational continuity.

Lead product security architecture and security-by-design across the product lifecycle. Embed security into SSDLC and DevSecOps, perform threat modeling and risk assessments, define controls for AI/ML products, manage post-market surveillance, oversee penetration and advanced testing, support incident response, partner with cross-functional stakeholders for regulatory compliance, track security metrics, and mentor other engineers.

Field-based sales role to drive adoption of GRAIL's Galleri multi-cancer early detection test. Develop and execute territory business plans, prospect primary care practices, onboard early adopters, deliver clinical education and value-based presentations, collaborate with cross-functional teams (MSLs, marketing, customer service), manage complex accounts, maintain CRM records, and ensure compliance with industry and company policies. Heavy in-person activity and travel to meet sales goals.

The Staff Quality Engineer ensures compliance in quality management systems, leads post-market surveillance, manages complaints, and collaborates cross-functionally to improve quality processes.

Lead and execute complex molecular biology and protein chemistry experiments, develop novel methods and workflows, analyze and present data, mentor junior scientists, ensure regulatory and lab compliance, and drive cross-functional research strategies to advance early cancer detection.

The Director of Government Affairs will lead advocacy strategies, build relationships with policymakers, and influence health policy to support early cancer detection.

Supervise a call-center customer service team, manage daily operations and workloads, coach and develop staff, handle escalations, monitor performance and SLAs, and collaborate cross-functionally to improve processes and customer satisfaction.

Lead and scale a global Data Platform engineering team to deliver a cloud-native, serverless microservices data platform. Define architecture and roadmaps for petabyte-scale data processing, AI/LLM-enabled features (RAG), high-throughput ETL, and secure REST APIs while ensuring CI/CD, DevOps, cost optimization, and regulatory compliance (HIPAA/GDPR).

Design, implement, and maintain hybrid enterprise network infrastructure across campus, lab, data center, and AWS. Configure Juniper/Aruba switching, Palo Alto firewalls, and AWS networking. Automate provisioning with Python/Ansible/Terraform, build monitoring and observability, troubleshoot complex connectivity and security issues, support lifecycle management, documentation, and participate in on-call rotations.