Top Startup Companies in the USA (10,000+)

We're Mochi Health, a pioneering force in obesity medicine dedicated to building personalized, clinically-backed weight care solutions. We're on a mission to empower patients with one-on-one virtual care and proven pharmaceutical treatments. We recognize that every body is unique, and believe weight loss plans should be, too. With over 100 million individuals struggling with obesity and 15 million already using GLP-1 prescriptions,...

Founded in 2015, Immuta is The Data Provisioning Company. We help organizations safely deliver governed data access to every consumer, whether human or AI. As enterprises move data to the cloud and adopt AI, they face a growing challenge: making data instantly available while maintaining compliance and control. Immuta solves this by automating data provisioning — the process of granting, governing,...

Click Therapeutics, Inc., develops, validates, and commercializes software as prescription medical treatments for people with unmet medical needs. As a leading innovator of Digital Therapeutics™, Click delivers accessible, clinically proven, FDA-regulated prescription treatments to the smartphone in your hand. Click’s treatments are defined by a commitment to applying technical and scientific rigor and patient-centric design to the development process. This...

Teachable was founded in 2014 to provide a solution that was missing for Creators in what was the early online courses space. Teachable is where seasoned creators around the world build their legacy through education. On Teachable, it’s easy to create high-quality courses, coaching, memberships, and digital downloads that help creators scale their businesses—and truly impact people's lives. With tools designed...

At Kensho, we leverage S&P Global’s world class data to research, develop and implement leading AI and machine learning capabilities that drive fact-based, objective decision making. Data is at the heart of Kensho, and it’s our technology. We build and deploy solutions that make that data accessible, insightful, relevant and transformative.

At AdAction, we’re revolutionizing how brands connect with audiences through the power of mobile technology. As leaders in performance-driven marketing, we create innovative solutions that merge supply, loyalty, and rewards into seamless, mobile-first strategies. Our platform empowers brands and app developers to drive engagement, boost retention, and achieve sustainable growth by delivering personalized, reward-based experiences that foster genuine connections. With cutting-edge...

Topline Pro believes that home service pros and small businesses are the backbone of the economy and have gone too long without the right technologies. Topline Pro is a Generative AI platform enabling home service businesses to be easily discovered, trusted and booked, directly. The AI-driven interface rapidly and affordably creates a custom, SEO-optimized website along with a application to...

Cie is a venture studio that serves as an innovation lab and accelerator for bold entrepreneurs who want to transform disruptive ideas into thriving ventures. Cie blends Silicon Valley DNA with the business maturity of serial entrepreneurs, seasoned venture capitalists, and Fortune 500 executives. Combined with the team’s strategic and operational expertise in technology, product development, brand building, and customer acquisition,...

Recognized by Crain’s as one of 2025’s Most Innovative Companies, UncommonX helps customers move from reactive defense to proactive resilience, with the context, prioritization, and insights needed to reduce risk and respond with precision. We believe cybersecurity should deliver more than alerts — it should deliver clarity, confidence, and control. That’s why we built an AI-powered Exposure Management platform that gives...

Kalderos is a data infrastructure and analytics company that’s solving challenges around drug discounts in the U.S. healthcare system. Through platform technology and big data, our team is delivering smart solutions that enable healthcare stakeholders to collaborate with greater transparency and trust. We’re passionate about our mission to take on the most stubborn challenges in healthcare. We also know that...

Mixbook is an award-winning design platform that gives people unrivaled creative freedom to tell their stories through beautiful, personalized photo goods. Since our start, we’ve helped more than 6 million people create one-of-a-kind books, cards, prints, and calendars, earning over 35,000+ 5-star reviews and becoming the #1 rated photo book service in the US. Our platform blends trend-forward design with a...

Who We Are Founded in 2001, Adage Technologies is a digital engineering firm building modern, AI‑enabled solutions that help organizations engage their audiences and operate more efficiently. With offices in Chicago and Medellín, our 120‑person team blends strategy, design, engineering, and data to create impactful digital experiences for performing arts organizations, associations and accreditation bodies, and manufacturing and distribution companies. What We...

American medicine is the best in the world. But the American healthcare system is challenged by high administrative costs that burden patients, health systems, and insurance companies with unnecessary expenses. We are focused on addressing those challenges. We use GenAI to improve the most pressing financial pain points in the revenue cycle. We’re one of the first companies to deploy GenAI...

We help customers of all sizes transform into true DevOps organizations. We've taken several customers from deploying applications once a month to hundreds of times a day. We're a team of experienced ServiceNow Wizards and passionate SRE's contributing to the open-source community, who have built multiple enterprise-scale CI/CD pipelines and integrations to help your organization build velocity in your release...

Turion Space is building the infrastructure to secure and sustain the future of space. Founded to address the growing need for space domain awareness, in-space servicing, and debris mitigation, Turion designs, builds, and operates spacecraft with real-world operational capability. Our vehicles are built for national security and commercial missions that require speed, autonomy, and resilience. We believe the next chapter of...

Technology has revolutionized the operations of public markets. The improvement in capabilities has raised investor expectations and regulatory demands, but the private markets can’t keep up. Global private markets manage $15 trillion dollars. Despite its importance in the global economy, investment managers still run their operations on a patchwork of legacy software providers and manual spreadsheets, creating massive inefficiencies and...

ASI is a dual-use software company that deploys predictive AI to the world's most complex operating environments. Backed by leading investors–including Andreessen Horowitz, Renegade Partners, and Spark Capital–we actively manage over 40% of all US air traffic across both public and private sector air operations. Partnering with major airlines like United and Alaska, we optimize thousands of flights daily, delivering...

Outset invented a better way to do research: AI-powered user interviews. We created this new category of research technology and now it's growing wildly. Global brands like Hubspot, Microsoft, Uber and Nestle use Outset to achieve deeper, qualitative insights about their users at unprecedented speed and scale. The research industry is massive (>$140B and growing) and ripe for disruption. Incumbents are outdated,...

LeafLink is the unified B2B cannabis platform, empowering thousands of licensed cannabis brands and retailers across North America with the tools and technology they need to streamline ordering, payments, and logistics. Our leadership is continually building a community of employees who embrace change, support one another, and deliver excellence. The trust and respect we have for our customers is matched only...

inKind's mission is to support the success of independent restaurants and hospitality groups by providing funding and enriching customers' dining experiences with the inKind platform. At inKind, we believe restaurants are integral parts of our communities, and recognize the economic realities of being a successful operator. To better support hospitality ventures, we created a unique funding model that focuses on...