Top Senior Python Jobs in Washington, DC

Reposted 2 Months AgoSaved
Hybrid
Washington, DC
Senior level
Senior level
Digital Media • Information Technology • Software
Lead client engagements and design cloud-native enterprise architectures. Define data schemas, produce technical proposals, mentor teams, participate in development, support pre-sales, and ensure solutions are delivered to production using best practices.
Top Skills: AWSAzureCdkCloud Development KitsFastapiGCPJavaPHPPythonRReactScala
Reposted 2 Months AgoSaved
In-Office
Washington, DC
Senior level
Senior level
Information Technology • Database • Consulting
The Data Architect will design and implement scalable data solutions, modernize data environments, and ensure compliance with federal data standards while mentoring teams and collaborating with stakeholders.
Top Skills: AWSAzureDatabricksDelta LakeGCPPythonSparkSQL
2 Months AgoSaved
In-Office
Washington, DC
Senior level
Senior level
Information Technology • Other • Software • Consulting
Designs and manages secure Azure cloud infrastructure and CI/CD pipelines in commercial and classified DoD environments. Responsibilities include Infrastructure as Code automation, pipeline security, DoD compliance, RMF documentation, vulnerability remediation, system monitoring, incident response, and high availability. The role also leads secure infrastructure requirements across teams and supports mission-critical data analytics and machine learning applications.
Top Skills: Aqua SecurityAzure CloudAzure Commercial CloudAzure DevopsAzure Devops PipelinesAzure Government CloudDatabricksDockerElasticsearchHadoopHelmInfrastructure As CodeKubernetesLinuxNessusNoSQLOpensearchPower BIPythonSonarqubeSparkSQLTableau
2 Months AgoSaved
In-Office
Washington, DC
Senior level
Senior level
Artificial Intelligence • Security
Design and operate secure, multi-account AWS infrastructure and EKS environments using Terraform. Manage shared developer services, CI/CD pipelines, observability, container platforms, and self-service automation. Support MLOps workloads and agentic AI workflows while collaborating with product teams. Ensure infrastructure and software supply chains meet CMMC Level 2, ATO, NIST, and FIPS requirements.
Top Skills: ArgocdArtifactoryAtoAWSAws Control TowerAws GovcloudBashCi/CdCloudFormationCmmcContainer RegistriesDockerEksElasticFipsGitlabGitopsGoHelmIamKubernetesMlopsNistPythonSIEMTerraformTerraform CloudTerraform EnterpriseVpc
2 Months AgoSaved
In-Office
Washington, DC
Senior level
Senior level
Artificial Intelligence • Security
Design, build, and maintain systems-level Rust software for an AI-powered autonomous drone platform. Integrate AI/ML pipelines, develop networking and protocol components, support autonomy features, and create reliable software for resource-constrained, low-latency environments. Develop and test through simulation while collaborating with ML engineers and contributing across application and systems layers.
Top Skills: Ai/MlC++Datalink SystemsDistributed SystemsEmbedded SystemsHitlNetworkingNixNixosProtocol ImplementationPub/Sub MessagingPythonRf CommunicationsRoboticsRustSensor Data ProcessingSitlTelemetryVideo Streaming
3 Months AgoSaved
Hybrid
Washington, DC
155K-190K Annually
Senior level
155K-190K Annually
Senior level
Aerospace • Cloud • Software • Defense • Automation
Develop backend Command & Control (C2) systems connecting Quindar's platform to satellites. Implement machine-to-machine communication, binary protocols, serialization, transport, stateful comms, telemetry, and hardware integrations. Onboard diverse spacecraft, translate interfaces into maintainable integrations, build scalable abstractions and tooling, and improve reliability, observability, and performance while collaborating cross-functionally.
Top Skills: Aes-256 CfbAes-256 EcbAes-256 GcmCcsdsCfdpCspDevsecopsGitGitIpKubernetesMibNsa Type 1 CaribouNsa Type 1 PegasusPythonRelational DatabasesRustTime-Series DatabasesXtce
Reposted 3 Months AgoSaved
In-Office
Washington, DC
170K-200K Annually
Senior level
170K-200K Annually
Senior level
Aerospace • Artificial Intelligence • Software • Defense
As a Senior Software Engineer, you will enhance user experience for maritime tech, develop a real-time data platform, and oversee large engineering projects.
Top Skills: GraphQLPythonReactTypescript
Reposted 3 Months AgoSaved
In-Office or Remote
Washington, DC
160K-180K Annually
Senior level
160K-180K Annually
Senior level
Artificial Intelligence • Machine Learning • Natural Language Processing • Security
Lead technical discovery with federal customers to define requirements and design secure, compliant cloud-native architectures. Build POCs/MVPs, produce architecture and deployment documentation, integrate third-party tools, guide implementations, and align sales, engineering, and product teams to deliver AI-driven knowledge management solutions for government environments.
Top Skills: Aws GovcloudAzure GovernmentCi-CdDeployment PipelinesEvent-Driven ArchitecturesExperiment TrackingFedrampFismaGCPGraphQLKnowledge Retrieval SystemsLlmsMlopsModel MonitoringModel VersioningNlpOrchestration FrameworksPythonRagRestful ApisSQLWebhooks
Reposted 3 Months AgoSaved
In-Office or Remote
Washington, DC
Senior level
Senior level
Security
Lead design, development, enhancement, and maintenance of enterprise geospatial applications and APIs. Implement ArcGIS Enterprise solutions, web GIS apps, dashboards, integrations, and ensure compliance with federal IT, cybersecurity, and privacy requirements while guiding development teams and supporting testing, deployment, and O&M.
Top Skills: .NetArcgis ApisArcgis EnterpriseArcgis Geoevent ServerArcgis SdksArcgis ServerC#C++Ci/CdCloud-NativeDevsecopsEsriJavaScriptKubernetesPython
3 Months AgoSaved
In-Office
Washington, DC
200K-250K Annually
Senior level
200K-250K Annually
Senior level
Big Data • Information Technology • Software • Analytics
Design, build, and operate Peregrine's cloud platform to improve performance, reliability, security, and cost-efficiency. Own infrastructure projects end-to-end, automate region/environment provisioning, implement autoscaling and right-sizing, harden security and compliance controls, improve incident response, and create developer-facing tooling and documentation. Mentor junior engineers and influence cross-team technical decisions.
Top Skills: AWSAzureContainersDockerGCPGoKubernetesPythonTerraform
Reposted 3 Months AgoSaved
In-Office
Washington, DC
Senior level
Senior level
Artificial Intelligence • Machine Learning • Software • Analytics
Build and maintain cloud-based infrastructure and CI/CD pipelines, automate deployments and workflows, support application deployment, and collaborate with cross-functional teams to improve reliability and scalability.
Top Skills: AWSAws LambdaDockerGitlabJenkinsKubernetesPostmanPythonRestful ApisS3SQLTerraform
Reposted 3 Months AgoSaved
In-Office
Washington, DC
60K-80K Annually
Senior level
60K-80K Annually
Senior level
Artificial Intelligence • Information Technology • Software • Consulting
Develop and maintain Ruby and Rails applications, write Bash scripts, troubleshoot performance and multithreading issues, optimize SQL/MySQL queries, administer Unix/Linux/Solaris servers, and collaborate in Agile teams. Participate in API and SOA development and use source control (SVN/Git).
Top Skills: .NetApacheAspBashC#C++ColdfusionCSSDomEmbperlGitJavaJavaScriptJspLinuxMac Os XMod_PerlMySQLObjective-CPerlPHPPythonRubotoRubyRuby On RailsSolarisSvnSwiftTcp/IpWindowsXhtmlXML
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Reposted 3 Months AgoSaved
In-Office
Washington, DC
60K-60K Annually
Senior level
60K-60K Annually
Senior level
Artificial Intelligence • Information Technology • Software • Consulting
Design and implement AWS infrastructure (VPC, S3, EBS, CloudWatch/Trail, IAM, Redshift, HSM), architect hybrid cloud models, support virtualization and VMware (vRealize/vRO/vRA), manage networking (DNS, IP, VPC peering), follow ITIL processes, and automate tasks using shell scripting/Python.
Top Skills: AWSAzureCloudtrailCloudwatchDnsEbsGCPHsmIamPythonRedshiftS3Shell ScriptingVMwareVpcVpc PeeringVraVrealizeVro
Reposted 3 Months AgoSaved
In-Office
Washington, DC
Senior level
Senior level
Information Technology • Software
The Sailpoint Consultant will maintain and support SailPoint IIQ infrastructure, troubleshoot issues, develop scripts, and assist project teams with identity and access solutions.
Top Skills: BashC#C++JbossLinuxOracle DatabasesPythonSailpoint IiqSQLWindows
Reposted 3 Months AgoSaved
In-Office
Washington, DC
Senior level
Senior level
Artificial Intelligence • Information Technology • Internet of Things • Software • Automation
Seeking a Big Data Engineer with 5+ years in data technologies, expertise in RDBMS, cloud storage, data architecture, and experience with Hadoop.
Top Skills: AWSGoogle Cloud PlatformHadoopMySQLPostgresPythonRSparkTableau
Reposted 3 Months AgoSaved
Hybrid
Washington, DC
207K-385K Annually
Senior level
207K-385K Annually
Senior level
Artificial Intelligence • Machine Learning • Generative AI
As a Forward Deployed Software Engineer, partner with high-impact public sector customers by developing full-stack applications and providing technical guidance throughout the project lifecycle.
Top Skills: AWSAzureJavaScriptKubernetesPythonTerraform
Reposted 3 Months AgoSaved
Hybrid
Washington, DC
174K-239K Annually
Senior level
174K-239K Annually
Senior level
Cloud
Design, build, and maintain cloud platform services for sensitive federal missions. Operate and monitor air-gapped, secure environments; build CI/CD pipelines without internet; maintain SLOs/SLIs; own runbooks and incident response; support POA&M and Authority to Operate activities; and deliver internal platform enablement while ensuring strict compliance and security.
Top Skills: Aws VpcsBgpCi/CdCloudwatchContainersEcs FargateEksGrafanaIpsecLinuxPythonSplunkTerraformTgwsVpc Endpoints
Reposted 3 Months AgoSaved
In-Office
Washington, DC
285K-356K Annually
Senior level
285K-356K Annually
Senior level
Artificial Intelligence • Big Data • Machine Learning
The Principal Architect & Technical Team Lead will guide a team in AI product development, oversee high-impact architectural decisions, and manage executive stakeholder engagement.
Top Skills: AWSAzureGCPJavaScriptKubernetesPythonTypescript
3 Months AgoSaved
In-Office
Washington, DC
Senior level
Senior level
Artificial Intelligence • Information Technology • Sales • Software
Build, operate, and modernize a cloud-native enterprise data platform powering SaaS AI products. Responsibilities include data ingestion, storage, querying, quality, governance, and operational excellence, collaborating with engineers to deliver scalable, maintainable solutions and refactor legacy systems.
Top Skills: Apache AirflowAzureAzure Blob StorageAzure Data FactoryBigQueryGCPGoogle Cloud StorageMicrosoft FabricMicrosoft Sql ServerPostgresPythonSQL
Reposted 3 Months AgoSaved
In-Office or Remote
Washington, DC
Senior level
Senior level
Information Technology
Design and build automated API onboarding, lifecycle management, deployment automation, and developer self-service. Implement REST APIs, infrastructure-as-code, CI/CD pipelines, and Git-based workflows. Integrate developer portals, API publishing/governance, and enterprise integration for a federal contractor environment.
Top Skills: AnsibleApi Lifecycle ManagementApi OnboardingAutomationCi/CdDeveloper PortalsGitGithub ActionsGitlabInfrastructure-As-CodeJavaJenkinsJSONKubernetesOpenshiftPythonRest ApiTerraformYaml
Reposted 3 Months AgoSaved
In-Office or Remote
Washington, DC
140K-180K Annually
Senior level
140K-180K Annually
Senior level
Big Data • Information Technology • Other
The Senior Enterprise Architect leads the design and implementation of network and cloud architectures, ensuring alignment with organizational goals and industry practices. Responsibilities include defining architecture frameworks, advising on cloud adoption, ensuring security compliance, and managing cross-functional teams.
Top Skills: AnsibleAWSAzureBgpGitGCPJenkinsMplsOspfPythonSd-WanTcp/IpTerraform
Reposted 3 Months AgoSaved
In-Office
Washington, DC
165K-230K Annually
Senior level
165K-230K Annually
Senior level
Aerospace • Other
Design, deploy, and automate core infrastructure (on‑prem and cloud) and manage Kubernetes and Linux fleets. Collaborate with engineers to build scalable, operable services and improve lifecycle: testing, CI/CD, deployment, monitoring, and performance.
Top Skills: AnsibleBashBazelCi/CdCloudDatabasesDistributed DatabasesKubernetesLinuxMakefilesMonitoringPythonStorageTcp/IpTerraform
Reposted 3 Months AgoSaved
In-Office
Washington, DC
195K-220K Annually
Senior level
195K-220K Annually
Senior level
Big Data • Software • Analytics
Manage and automate infrastructure for on-prem and cloud deployments using infrastructure-as-code. Build, deploy, and operate services (containers, orchestration, fleet management), improve observability and availability, support security practices, and collaborate with cross-functional teams to scale and operationalize ML and web applications.
Top Skills: AnsibleApache AirflowAWSDockerGanetiGitGoHadoopJenkinsKubernetesLinuxMavenNagiosNode.jsPostgresPythonReactScalaUbuntu
Reposted 3 Months AgoSaved
Hybrid
Washington, DC
146K-280K Annually
Senior level
146K-280K Annually
Senior level
Artificial Intelligence • Machine Learning • Generative AI
As a Forward Deployed Engineer, you will lead government AI model deployments, design full-stack systems, and ensure successful integrations and relationships with public sector stakeholders.
Top Skills: AWSAzureJavaScriptKubernetesPythonTerraform
Reposted 3 Months AgoSaved
Hybrid
Washington, DC
211K-335K Annually
Senior level
211K-335K Annually
Senior level
Artificial Intelligence • Machine Learning • Generative AI
Lead solutions architecture for government clients, embedding with stakeholders to deploy GenAI solutions, and ensuring project success through prototype development and technical guidance.
Top Skills: JavaScriptOpenai ApiPython
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