Top Senior Python Jobs in Washington, DC

Design, build, and operate Peregrine's cloud platform to improve performance, reliability, security, and cost-efficiency. Own infrastructure projects end-to-end, automate region/environment provisioning, implement autoscaling and right-sizing, harden security and compliance controls, improve incident response, and create developer-facing tooling and documentation. Mentor junior engineers and influence cross-team technical decisions.

Build and maintain cloud-based infrastructure and CI/CD pipelines, automate deployments and workflows, support application deployment, and collaborate with cross-functional teams to improve reliability and scalability.

As a Senior DevOps Specialist, you will enhance infrastructure, oversee CI/CD systems, ensure security compliance, and implement AI tools to streamline DevOps processes.

Build and lead full‑stack web applications: design and implement front-end and back-end services, RESTful APIs, and relational databases; maintain CI/CD pipelines, automated testing, and observability; work with clients, mentor teammates, and deliver Agile software solutions. Requires TS/SCI with polygraph.

Develop and maintain Ruby and Rails applications, write Bash scripts, troubleshoot performance and multithreading issues, optimize SQL/MySQL queries, administer Unix/Linux/Solaris servers, and collaborate in Agile teams. Participate in API and SOA development and use source control (SVN/Git).

Design and implement AWS infrastructure (VPC, S3, EBS, CloudWatch/Trail, IAM, Redshift, HSM), architect hybrid cloud models, support virtualization and VMware (vRealize/vRO/vRA), manage networking (DNS, IP, VPC peering), follow ITIL processes, and automate tasks using shell scripting/Python.

Customer-facing senior engineer who designs, builds, and productionizes end-to-end data and AI solutions on Databricks. Leads architecture, implements data pipelines, integrates ML/AI models, delivers production deployments, and produces reusable assets while collaborating with customers and cross-functional teams.

The Sailpoint Consultant will maintain and support SailPoint IIQ infrastructure, troubleshoot issues, develop scripts, and assist project teams with identity and access solutions.

Seeking a Big Data Engineer with 5+ years in data technologies, expertise in RDBMS, cloud storage, data architecture, and experience with Hadoop.

As a Forward Deployed Software Engineer, partner with high-impact public sector customers by developing full-stack applications and providing technical guidance throughout the project lifecycle.

Design, build, and maintain cloud platform services for sensitive federal missions. Operate and monitor air-gapped, secure environments; build CI/CD pipelines without internet; maintain SLOs/SLIs; own runbooks and incident response; support POA&M and Authority to Operate activities; and deliver internal platform enablement while ensuring strict compliance and security.

The Principal Architect & Technical Team Lead will guide a team in AI product development, oversee high-impact architectural decisions, and manage executive stakeholder engagement.

Design and build a novel, highly scalable data infrastructure to aggregate and stage simulation outputs and user inputs for LLM consumption. Architect massive batch pipelines, complex relational data models, and low-latency distributed processing. Lead technical direction, solve ambiguous first-principles problems, and optimize data for downstream AI decision systems supporting government customers.

Build and own user-facing product experiences (Search, Dossier, Maps, Dashboards, etc.), collaborate with design and product, ship fast, reliable full‑stack features, integrate AI/semantic discovery, optimize latency and resilience, and iterate with deployment and users.

Design, maintain, and govern databases that support project controls (cost, schedule, EVM). Ensure availability, performance, security, and data quality. Integrate systems (Primavera, EcoSys, Power BI), build ETL pipelines and automation (SQL, Python), enable reporting, and support project controls teams with governance, monitoring, and user training.

Embed with a single U.S. Intelligence Community customer to architect, build, deploy, secure, and operate OCI-based cloud solutions. Lead Infrastructure-as-Code, automation, networking, identity, container platforms, observability, and production hardening. Own delivery outcomes and drive adoption, troubleshooting, and knowledge transfer while influencing Oracle product direction.

Design and implement scalable, noise-aware quantum circuit simulators (state-vector, tensor-network, stabilizer) and error‑correction pipelines. Integrate hardware-specific noise models, mid-circuit measurement and decoders, and optimize simulation pipelines for HPC, GPUs, or distributed systems. Collaborate with hardware and algorithm teams, prototype new simulation methods, and support performance estimation and business development.

Build, operate, and modernize a cloud-native enterprise data platform powering SaaS AI products. Responsibilities include data ingestion, storage, querying, quality, governance, and operational excellence, collaborating with engineers to deliver scalable, maintainable solutions and refactor legacy systems.

Design and build automated API onboarding, lifecycle management, deployment automation, and developer self-service. Implement REST APIs, infrastructure-as-code, CI/CD pipelines, and Git-based workflows. Integrate developer portals, API publishing/governance, and enterprise integration for a federal contractor environment.

As a Lead Software Engineer, you will integrate Applied Intuition's vehicle intelligence products with defense and government customers, overseeing technical execution for complex systems.

The Senior Enterprise Architect leads the design and implementation of network and cloud architectures, ensuring alignment with organizational goals and industry practices. Responsibilities include defining architecture frameworks, advising on cloud adoption, ensuring security compliance, and managing cross-functional teams.

Design, deploy, and automate core infrastructure (on‑prem and cloud) and manage Kubernetes and Linux fleets. Collaborate with engineers to build scalable, operable services and improve lifecycle: testing, CI/CD, deployment, monitoring, and performance.

Ensure reliability, availability, and performance of on-premises, cloud, and hybrid systems. Implement monitoring, automated alerting, incident response, automation, chaos engineering, and rollback/recovery. Build dashboards, runbooks, and scripts; analyze capacity and performance; respond to outages and conduct post-incident reviews. Collaborate with development, cloud, and cybersecurity teams and implement security best practices across operations.

Provide hands-on administration, modernization, security, automation, and cloud migration for the Department of Education OIG's Oracle databases, middleware, analytics, identity, and storage. Perform patching, tuning, OCI migrations, automation scripting, monitoring, backup/recovery, documentation, and knowledge transfer while supporting hybrid on-premises and Oracle Cloud environments.

Design, develop, and review software as part of an Agile scrum team. Collaborate with architects, QA, analysts, and customers to build large-scale hosted applications, contribute to security and risk assessments, resolve operational issues, and participate in on-call support and deployments.