Top Senior Python Jobs in Washington, DC

Build and operate a multi-account AWS developer platform using Terraform and Terraform Enterprise. Provision and manage EKS clusters, shared services (GitLab, Artifactory), CI/CD pipelines, and self-service automation. Support MLOps workloads, observability, and security compliance (CMMC, NIST, FIPS) while collaborating with product teams to enable scalable, secure infrastructure and developer tooling.

Develop and maintain Rust-based systems software for an autonomous drone platform. Design low-latency, high-reliability services across networking, protocols, embedded platforms, and AI/ML integration. Work with simulation environments and collaborate with ML engineers to enable autonomy features under constrained, real-world conditions.

Engineer software that connects AI-driven platforms to datacenter power infrastructure. Develop control strategies and optimize energy use and AI workloads.

The Software Engineer II will develop backend services and APIs while also contributing to frontend React components, focusing on digital services for federal clients.

Design, build, and operate secure, production infrastructure spanning cloud-native and air-gapped edge deployments. Own Kubernetes multi-cluster operations, hardened artifact pipelines, monitoring/incident response, and embed security and compliance (STIGs, CVE remediation, FedRAMP/JWICS) into platform delivery while collaborating across product, engineering, and GRC.

Lead technical customer engagements to design, deploy, and modernize data orchestration platforms on Astro/Airflow. Run architecture reviews, build prototypes, diagnose and resolve production issues, ensure scalability, observability, and security, and produce reusable tools and reference architectures to improve delivery quality.

The role involves designing, optimizing, and maintaining PostgreSQL and MySQL databases, ensuring high availability, reliability, and performance for mission-critical systems, while automating operational tasks and responding to incidents.

The Senior Forward Deployed Engineer will lead the development of innovative AI solutions for public sector clients, focusing on mission-critical projects while mentoring junior engineers and collaborating closely with users to ensure bespoke solutions meet operational needs.

Maintain and improve reliability, scalability, and performance of enterprise infrastructure across global sites. Implement automation and infrastructure-as-code, build monitoring and observability, perform RCA and incident response, support patching and RMF changes, integrate new capabilities, and maintain operational documentation and ITIL/ITSM processes to ensure mission-ready, high-availability environments.

Senior Linux Systems Engineer to administer, optimize, secure, and automate enterprise Linux systems across virtualization and cloud environments. Responsibilities include performance tuning, patch management, troubleshooting, automation scripting, documentation, and collaboration with application teams to ensure scalable, compliant, mission-critical infrastructure.

Provide Tier III database administration and O&M support for enterprise applications: monitor and tune SQL Server/MySQL, resolve critical incidents, maintain environments, manage backups/recovery, update documentation, support SDLC/Agile processes, and coordinate security and operational tasks.

Senior individual contributor owning design, implementation, and operation of infrastructure systems. Drive technical direction, write RFCs, lead on-call escalations and post-incident reviews, mentor engineers, eliminate systemic toil, and partner with security, compliance, product, and ops to deliver scalable, deployable ground-station infrastructure.

Lead development and validation of advanced passive RF geolocation algorithms (TDOA, FDOA, interferometry). Build high-fidelity simulations, implement real-time software on DSP/GPU/FPGA, integrate with RF/SDR hardware, define RF/timing requirements, and support system calibration and field validation. Collaborate across engineering, production, and business teams; travel up to 30% and work on-site multiple days weekly.

Lead development of passive RF geolocation algorithms (TDOA, FDOA, interferometry) from first principles through simulation, real-time implementation, integration, calibration, and field validation. Build high-fidelity simulation environments, quantify performance under real-world impairments, and partner with hardware and systems teams to define RF/timing requirements and support field demonstrations.

Lead technical discovery with federal customers to define requirements and design secure, compliant cloud-native architectures. Build POCs/MVPs, produce architecture and deployment documentation, integrate third-party tools, guide implementations, and align sales, engineering, and product teams to deliver AI-driven knowledge management solutions for government environments.

Lead end-to-end integration and deployment of vehicle intelligence products for defense customers, spanning software engineering, OS configuration, system deployment, and hardware integration. Design scalable architectures, collaborate with product and engineering teams, and own technical outcomes in fast-changing, operational environments to ensure mission success.

Lead design, development, enhancement, and maintenance of enterprise geospatial applications and APIs. Implement ArcGIS Enterprise solutions, web GIS apps, dashboards, integrations, and ensure compliance with federal IT, cybersecurity, and privacy requirements while guiding development teams and supporting testing, deployment, and O&M.

Architect, build, and deploy enterprise-grade full stack applications with React front ends and scalable back ends. Use AI-assisted tools and agentic workflows to rapidly prototype and iterate, ensure secure public-facing production readiness, implement authentication/authorization and cloud-based architectures, and partner with stakeholders to evolve prototypes into production systems.

Operate, monitor, and maintain Astronomer's managed Airflow platform and underlying cloud/Kubernetes infrastructure. Troubleshoot customer environments, participate in on-call rotation, build monitoring/automation, improve observability, and work directly with customers to meet SLAs and drive reliability.

Build and maintain cloud-based infrastructure and CI/CD pipelines, automate deployments and workflows, support application deployment, and collaborate with cross-functional teams to improve reliability and scalability.

As a Senior DevOps Specialist, you will enhance infrastructure, oversee CI/CD systems, ensure security compliance, and implement AI tools to streamline DevOps processes.

The Software Engineer will build scalable backend services, optimize performance, and mentor peers, focusing on distributed systems development.

Responsible for architecting solutions that align with CMS needs, managing complex programs, and mentoring future technologists while adhering to federal standards.

The Senior Software Engineer will direct technical architecture decisions while developing AI/ML-enabled data access technology. They will leverage experience in building mission-critical services and have strong knowledge in AWS and Python frameworks.

The Senior Embedded Software Engineer will design and develop software for embedded systems, focusing on security, integration, and collaboration with hardware teams.