Top Senior Python Jobs in Washington, DC

Reposted 24 Days AgoSaved
In-Office
Washington, DC
Senior level
Senior level
Information Technology • Database • Consulting
The Data Architect will design and implement scalable data solutions, modernize data environments, and ensure compliance with federal data standards while mentoring teams and collaborating with stakeholders.
Top Skills: AWSAzureDatabricksDelta LakeGCPPythonSparkSQL
26 Days AgoSaved
In-Office
Washington, DC
91K-185K Annually
Senior level
91K-185K Annually
Senior level
Artificial Intelligence • Information Technology • Consulting • Cybersecurity
Supports implementation and operational sustainment of a COTS physical access system in government environments. Responsibilities include installation, configuration, validation, troubleshooting, infrastructure coordination, networking, server and virtualization administration, SQL Server support, identity and access management, API integration, compliance documentation, security assessments, and vendor coordination. The role also communicates technical risks and status to stakeholders and requires onsite work in Washington, DC with an active Top Secret clearance.
Top Skills: AgileConfluenceHyper-VJIRAKanbanLinuxMicrosoft Entra IdMicrosoft GraphMicrosoft Sql ServerPowershellPythonScrumVMwareWindows
26 Days AgoSaved
In-Office
Washington, DC
Senior level
Senior level
Information Technology • Other • Software • Consulting
Designs and manages secure Azure cloud infrastructure and CI/CD pipelines in commercial and classified DoD environments. Responsibilities include Infrastructure as Code automation, pipeline security, DoD compliance, RMF documentation, vulnerability remediation, system monitoring, incident response, and high availability. The role also leads secure infrastructure requirements across teams and supports mission-critical data analytics and machine learning applications.
Top Skills: Aqua SecurityAzure CloudAzure Commercial CloudAzure DevopsAzure Devops PipelinesAzure Government CloudDatabricksDockerElasticsearchHadoopHelmInfrastructure As CodeKubernetesLinuxNessusNoSQLOpensearchPower BIPythonSonarqubeSparkSQLTableau
26 Days AgoSaved
In-Office or Remote
Washington, DC
130K-160K Annually
Senior level
130K-160K Annually
Senior level
Security
Support enterprise managed file transfer operations, Linux and Windows systems, servers, storage, networks, cybersecurity tools, and cloud environments. Administer and troubleshoot infrastructure, configure Axway Secure Transport, support secure high-volume data exchanges, and assist with AWS, security, automation, documentation, training, vendor coordination, modernization, cost estimation, and migration planning.
Top Skills: Active DirectoryAmazon Aurora MysqlAmazon Aurora PostgresqlAmazon CloudwatchAmazon Ec2Amazon EfsAmazon RdsAmazon S3Application Load BalancerAvailability ZonesAWSAws AcmAws ArmAws AwfAws CdkAws CliAws CloudformationAws CloudtrailAws CodepipelineAws IamAws Management ConsoleAws Security GroupsAws Transit GatewayAws VpcAxway Secure TransportAxway SentinelBashCi/CdFtpsGitGithub ActionsGitlabHttpsLdapManaged File TransferNetskopeNetwork Load BalancerOktaOraclePowershellPythonRocky LinuxSftpSslSymantec DlpSymantec SpeTerraformTlsTwo-Factor AuthenticationWindows Server 2022
Reposted 26 Days AgoSaved
In-Office
Washington, DC
121K-165K Annually
Senior level
121K-165K Annually
Senior level
Energy
Lead design and implementation of automated test frameworks and V&V for web, API, data, and backend systems. Integrate testing into CI/CD, support audit readiness and compliance (ASME NQA-1), manage defects and root-cause analysis, and drive quality metrics, documentation, and continuous improvement across engineering teams in a regulated nuclear environment.
Top Skills: APIsAzure DevopsC#Ci/CdCypressDatabasesDistributed SystemsGitJavaJavaScriptJIRAPlaywrightPytestPythonQmsRecords Control PlatformsSeleniumTestngTypescript
Reposted 26 Days AgoSaved
In-Office
Washington, DC
121K-165K Annually
Senior level
121K-165K Annually
Senior level
Energy
Build and run backend, data, and integration layers for a nuclear-scale platform. Own CI/CD, integrations (APIs, event streams, data pipelines), platform performance, and a unified front-end layer. Support data ontology and MCP design to enable safe AI agent access, collaborate with data scientists and product engineers, and maintain platform reliability and configuration baselines.
Top Skills: AWSCi/CdConfiguration ManagementData ModelingData PipelinesEvent StreamsGoInfrastructure As CodeJavaModel Context Protocol (Mcp)PythonRest ApisTypescript
Reposted 26 Days AgoSaved
In-Office
Washington, DC
195K-235K Annually
Senior level
195K-235K Annually
Senior level
Fintech • Payments • Financial Services
Lead end-to-end engineering projects building Node.js backends and React frontends, scale core APIs to millions of requests, debug using monitoring/logging, participate in code reviews and hiring, and collaborate on product roadmap driven by customer needs.
Top Skills: AchAWSCi/CdCloudflareData PipelinesJavaJavaScriptNode.jsPythonReactRtp
27 Days AgoSaved
In-Office or Remote
Washington, DC
182K-250K Annually
Senior level
182K-250K Annually
Senior level
Big Data • Machine Learning • Software • Analytics • Big Data Analytics
Build and productionize data and AI solutions for federal government customers using Databricks. Lead architecture, design, and implementation of end-to-end data engineering, machine learning, and application systems. Deliver secure, scalable production architectures, integrate customer systems, guide technical projects, train customers, and collaborate with engineering, product, support, and customer stakeholders. Contribute reusable frameworks and accelerators while managing technical delivery and customer relationships.
Top Skills: Ai ApisSparkAWSAzureCi/CdDatabricksGCPJavaScriptMl/Ai ModelsMlopsPythonScalaTypescript
27 Days AgoSaved
In-Office or Remote
Washington, DC
182K-250K Annually
Senior level
182K-250K Annually
Senior level
Big Data • Machine Learning • Software • Analytics • Big Data Analytics
Build and productionize data and AI solutions for federal customers using Databricks. Own architecture, design decisions, data pipelines, ML/AI integrations, and user-facing applications. Lead technical delivery, advise customers, integrate client systems, provide training, and collaborate with engineering, product, support, and project teams. Contribute reusable frameworks and best practices while managing complex stakeholder relationships and delivering secure, scalable production systems.
Top Skills: Ai ApisSparkAWSAzureCi/CdDatabricksGCPJavaScriptMl/Ai ModelsMlopsPythonScalaTypescript
27 Days AgoSaved
In-Office
Washington, DC
Senior level
Senior level
Artificial Intelligence • Security
Design and operate secure, multi-account AWS infrastructure and EKS environments using Terraform. Manage shared developer services, CI/CD pipelines, observability, container platforms, and self-service automation. Support MLOps workloads and agentic AI workflows while collaborating with product teams. Ensure infrastructure and software supply chains meet CMMC Level 2, ATO, NIST, and FIPS requirements.
Top Skills: ArgocdArtifactoryAtoAWSAws Control TowerAws GovcloudBashCi/CdCloudFormationCmmcContainer RegistriesDockerEksElasticFipsGitlabGitopsGoHelmIamKubernetesMlopsNistPythonSIEMTerraformTerraform CloudTerraform EnterpriseVpc
27 Days AgoSaved
In-Office
Washington, DC
Senior level
Senior level
Artificial Intelligence • Security
Design, build, and maintain systems-level Rust software for an AI-powered autonomous drone platform. Integrate AI/ML pipelines, develop networking and protocol components, support autonomy features, and create reliable software for resource-constrained, low-latency environments. Develop and test through simulation while collaborating with ML engineers and contributing across application and systems layers.
Top Skills: Ai/MlC++Datalink SystemsDistributed SystemsEmbedded SystemsHitlNetworkingNixNixosProtocol ImplementationPub/Sub MessagingPythonRf CommunicationsRoboticsRustSensor Data ProcessingSitlTelemetryVideo Streaming
Reposted 27 Days AgoSaved
In-Office
Washington, DC
123K-145K Annually
Senior level
123K-145K Annually
Senior level
Music
Lead design, development, and maintenance of scalable automated test frameworks for web and mobile apps. Integrate tests into CI/CD, expand regression coverage, validate APIs and services, reduce flaky tests, and collaborate with Engineering, Product, QA, and DevOps to improve release quality and testing efficiency.
Top Skills: Azure DevopsCi/CdCypressGithub ActionsGitlab CiJavaJavaScriptJenkinsMobile Test AutomationPlaywrightPythonRest ApisSeleniumTypescriptWeb Test Automation
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Reposted 27 Days AgoSaved
In-Office or Remote
Washington, DC
79K-241K Annually
Senior level
79K-241K Annually
Senior level
Legal Tech
Design, build, and maintain web application infrastructure and data systems for interactive information experiences. Lead application architecture, code quality, performance, and reliability; integrate generative AI and prototype XR interfaces; collaborate with designers and data scientists; ensure security, accessibility, scalability, and document technical standards.
Top Skills: AzureCi/CdData ApisData PipelineExtended Reality (Xr)Generative AiJavaScriptLlm ApisPythonReactSpatial ComputingTypescriptVue
29 Days AgoSaved
In-Office
Washington, DC
87K-198K Annually
Senior level
87K-198K Annually
Senior level
Information Technology
Design, develop, integrate, test, and maintain end-to-end software solutions. Build backend services, RESTful APIs, data integrations, and user-facing features using frontend frameworks. Participate in technical design, code reviews, troubleshooting, CI/CD, and Agile practices while collaborating with architects, product owners, and stakeholders. TS/SCI with polygraph required.
Top Skills: AngularCi/CdCloudFormationGithub ActionsGitlabJenkinsJIRAKubernetesPostgresPythonReactRestful ApisSQL
29 Days AgoSaved
Hybrid
Washington, DC
155K-190K Annually
Senior level
155K-190K Annually
Senior level
Aerospace • Cloud • Software • Defense • Automation
Develop backend Command & Control (C2) systems connecting Quindar's platform to satellites. Implement machine-to-machine communication, binary protocols, serialization, transport, stateful comms, telemetry, and hardware integrations. Onboard diverse spacecraft, translate interfaces into maintainable integrations, build scalable abstractions and tooling, and improve reliability, observability, and performance while collaborating cross-functionally.
Top Skills: Aes-256 CfbAes-256 EcbAes-256 GcmCcsdsCfdpCspDevsecopsGitGitIpKubernetesMibNsa Type 1 CaribouNsa Type 1 PegasusPythonRelational DatabasesRustTime-Series DatabasesXtce
29 Days AgoSaved
In-Office
Washington, DC
170K-216K Annually
Senior level
170K-216K Annually
Senior level
Information Technology • Consulting
Design, develop, test, and sustain secure cross-platform iOS and Android applications and supporting web/back-end systems. Build REST APIs, SQL-backed services, automation scripts, telemetry and operational tools; apply secure coding practices; troubleshoot integrations, networking, and Linux environments; document architecture and SOPs; and collaborate with security, backend, UC, and government stakeholders in a classified DoD/federal environment.
Top Skills: AndroidBashCisco UcCross-Platform MobileCSSHTMLiOSJavaJavaScriptLinuxMicrosoft Sql ServerPostgresPowershellPythonRest ApisRtpSipSQLTypescriptVpn
Reposted 29 Days AgoSaved
In-Office
Washington, DC
160K-180K Annually
Senior level
160K-180K Annually
Senior level
Security • Software
Own and evolve cloud-native and HPC infrastructure to maximize reliability, security, cost-efficiency, and developer experience. Build self-service platforms, integrate MLOps for GPU deployments, support SLURM-based scientific workloads, implement monitoring and CI/CD, adopt AI-powered developer and ops tooling, and participate in on-call to maintain production availability.
Top Skills: AWSAws ParallelclusterAzureAzure CyclecloudCi/CdClaude CodeCrossplaneDatadogElk StackGCPGithub CopilotGoGpuGrafanaHpcKubernetesLustreMlopsNfsNode.jsPrometheusPythonSlurmTerraform
Reposted One Month AgoSaved
In-Office
Washington, DC
80K-210K Annually
Senior level
80K-210K Annually
Senior level
Artificial Intelligence • Logistics • Software • Defense
Design, build, and operate secure, production infrastructure spanning cloud-native and air-gapped edge deployments. Own Kubernetes multi-cluster operations, hardened artifact pipelines, monitoring/incident response, and embed security and compliance (STIGs, CVE remediation, FedRAMP/JWICS) into platform delivery while collaborating across product, engineering, and GRC.
Top Skills: Air-Gapped AppliancesApplication StreamingArtifact PipelineAWSAws GovcloudAzureAzure GovernmentCi/CdCloudFormationCve RemediationFedrampGoJwicsKubernetesKubernetes OperatorsMulti-Cluster KubernetesPalantir FoundryPythonRustSecrets ManagementSoc 2StigsTerraformTypescript
Reposted One Month AgoSaved
In-Office
Washington, DC
111K-150K Annually
Senior level
111K-150K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Provide Tier III database administration and O&M support for enterprise applications: monitor and tune SQL Server/MySQL, resolve critical incidents, maintain environments, manage backups/recovery, update documentation, support SDLC/Agile processes, and coordinate security and operational tasks.
Top Skills: Activity MonitorAnsibleBashDynamic Management ViewsExcelExtended EventsGitJIRALampLinuxMicrosoft Sql ServerMySQLMysql WorkbenchPerformance MonitorPHPPowerPointPythonServicenowSharepointSql ProfilerSql Server Integration Services (Ssis)SsmsT-SqlVeritas NetbackupVisioVisual Studio CodeWindowsWordYaml
Reposted One Month AgoSaved
In-Office
Washington, DC
128K-173K Annually
Senior level
128K-173K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Maintain and improve reliability, scalability, and performance of enterprise infrastructure across global sites. Implement automation and infrastructure-as-code, build monitoring and observability, perform RCA and incident response, support patching and RMF changes, integrate new capabilities, and maintain operational documentation and ITIL/ITSM processes to ensure mission-ready, high-availability environments.
Top Skills: AnsibleElkNagiosPowershellPythonScomSolarwindsSplunkTerraform
Reposted One Month AgoSaved
In-Office
Washington, DC
170K-200K Annually
Senior level
170K-200K Annually
Senior level
Aerospace • Artificial Intelligence • Software • Defense
As a Senior Software Engineer, you will enhance user experience for maritime tech, develop a real-time data platform, and oversee large engineering projects.
Top Skills: GraphQLPythonReactTypescript
Reposted One Month AgoSaved
In-Office or Remote
Washington, DC
160K-180K Annually
Senior level
160K-180K Annually
Senior level
Artificial Intelligence • Machine Learning • Natural Language Processing • Security
Lead technical discovery with federal customers to define requirements and design secure, compliant cloud-native architectures. Build POCs/MVPs, produce architecture and deployment documentation, integrate third-party tools, guide implementations, and align sales, engineering, and product teams to deliver AI-driven knowledge management solutions for government environments.
Top Skills: Aws GovcloudAzure GovernmentCi-CdDeployment PipelinesEvent-Driven ArchitecturesExperiment TrackingFedrampFismaGCPGraphQLKnowledge Retrieval SystemsLlmsMlopsModel MonitoringModel VersioningNlpOrchestration FrameworksPythonRagRestful ApisSQLWebhooks
Reposted One Month AgoSaved
In-Office or Remote
Washington, DC
Senior level
Senior level
Security
Lead design, development, enhancement, and maintenance of enterprise geospatial applications and APIs. Implement ArcGIS Enterprise solutions, web GIS apps, dashboards, integrations, and ensure compliance with federal IT, cybersecurity, and privacy requirements while guiding development teams and supporting testing, deployment, and O&M.
Top Skills: .NetArcgis ApisArcgis EnterpriseArcgis Geoevent ServerArcgis SdksArcgis ServerC#C++Ci/CdCloud-NativeDevsecopsEsriJavaScriptKubernetesPython
Reposted One Month AgoSaved
In-Office
Washington, DC
Senior level
Senior level
Aerospace • Hardware • Software • Database • Defense • Industrial
Senior individual contributor owning design, implementation, and operation of infrastructure systems. Drive technical direction, write RFCs, lead on-call escalations and post-incident reviews, mentor engineers, eliminate systemic toil, and partner with security, compliance, product, and ops to deliver scalable, deployable ground-station infrastructure.
Top Skills: ArgocdAWSBgpCi/CdCloudflareContainersEksFortigateGitopsGoGovcloudIpsecK3SKubernetesLinuxLog PipelinesObservabilityPrometheusPythonSecrets ManagementSIEMSwitchingTerraformTgwVaultVictoriametricsWireguard
One Month AgoSaved
In-Office
Washington, DC
122K-173K Annually
Senior level
122K-173K Annually
Senior level
Cloud
Provision and deploy network devices, servers, and infrastructure for global POPs using automation (Ansible, Chef, Git). Troubleshoot provisioning issues, collaborate with hardware and operations teams, improve standards and tooling, and support post-deployment validation and handoff to Network Operations.
Top Skills: AnsibleBashBgpCdnChefGitGitLinuxPythonTcp/IpTravis
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