Top Senior Python Jobs in Washington, DC

Designs and develops cloud architecture across on-premises and cloud environments, implements infrastructure automation using DevSecOps and IaC, migrates applications, establishes secure and highly available cloud services, and optimizes performance and cost. The role also includes monitoring, troubleshooting, documentation, recovery planning, and supporting PaaS, IaaS, SaaS, and DaaS implementations across multiple enclaves.

Designs and develops cloud architecture and applications across on-premises and cloud environments. Implements infrastructure automation and DevSecOps practices, supports application migration, establishes secure and highly available cloud environments, and optimizes cost and performance. Responsibilities include cloud service delivery models, monitoring, troubleshooting, recovery planning, documentation, policy management, and development of new or enhanced cloud software across multiple enclaves.

Designs, secures, automates, and supports hybrid cloud infrastructure and enterprise platforms, with primary ownership of Azure infrastructure and Azure Databricks. Builds infrastructure-as-code modules, CI/CD pipelines, monitoring, security controls, and automation while supporting AWS, BigQuery, Wasabi, and on-premises environments. The role also handles incident response, vulnerability remediation, disaster recovery, cost optimization, documentation, and technical guidance for application deployments and platform architecture.

Provides senior-level engineering and operations support for enterprise applications, integration and middleware platforms, SaaS environments, APIs, release pipelines, and application security. Responsibilities include resolving complex incidents, engineering integrations, administering platforms, implementing monitoring and automation, supporting CI/CD and environment management, improving performance and reliability, and aligning security controls with Federal requirements. The role also contributes to Agile delivery, documentation, compliance, and technical coordination across application, infrastructure, security, and vendor teams.

Designs, develops, tests, and maintains ITSM automation workflows, scripts, integrations, event management, self-service tools, dashboards, and reporting. Analyzes ITSM processes to identify automation opportunities, integrates platforms with enterprise systems through APIs and webhooks, supports AIOps capabilities, documents solutions, monitors performance, and collaborates with service desk, operations, and business stakeholders in Agile delivery environments.

Design, develop, and deploy cloud applications in a secure Army cloud environment. Modernize a large-scale document management and search platform, optimize indexing and metadata for over 100 million documents, integrate generative AI and machine learning, and improve scalability. Responsibilities also include cloud security controls, system administration, DevSecOps, CI/CD, database optimization, user interface development, maintenance, and support within a hybrid government environment.

Leads and develops a software engineering team building customer-facing competitive intelligence products. Responsibilities include setting technical direction, translating priorities into execution plans, guiding architecture and quality, managing incidents, recruiting engineers, improving processes, and promoting responsible AI-assisted development. The role requires close collaboration with Product and Engineering leadership and is based in Rosslyn, Virginia, with at least three office days per week.

Lead the design, development, deployment, and operation of complex production software for Yext’s Competitive Intelligence products. Provide technical leadership, mentor engineers, guide architecture and technical planning, lead incident response, collaborate across teams, participate in recruiting, and promote high engineering standards. Build customer-facing experiences involving data, AI, visualizations, user interfaces, and agentic workflows while responsibly using and evaluating AI-assisted development tools.

Lead and mentor software engineers while driving architecture, code quality, delivery processes, deployment reliability, and technical excellence. Collaborate with product and design stakeholders on roadmaps and deliverables, provide hands-on technical guidance, mitigate project risks, and support hiring and team development. The role requires expertise in software engineering, scalable architectures, databases, APIs, distributed systems, DevOps, and high-performance applications within a remote, fast-paced environment.

Develop and maintain Terraform-based multi-cloud infrastructure across AWS, GovCloud, GCP, and Azure. Build CI/CD pipelines, integrate cloud provisioning with a unified portal and service catalog, implement authentication and RBAC, and embed security scanning and compliance controls. Manage containerized environments, Iron Bank images, artifact repositories, and SonarQube infrastructure while supporting secure automation across cloud enclaves.

Owns the IT aspects of mergers and acquisitions, including technical due diligence, risk assessment, integration planning, migrations, cutovers, and systems retirement. The role administers identity, applications, endpoints, infrastructure, and collaboration platforms while building automation and an M&A playbook. It partners with Security, Legal, Corporate Development, People, Finance, and IT teams, and contributes to broader Corporate Systems projects when acquisition work is limited.

Develop and maintain full-stack software with a primary focus on React Native mobile applications for Android. Design, test, deploy, and troubleshoot production systems using cloud infrastructure, containers, and CI/CD. Collaborate with Product and Design, participate in code reviews and Agile ceremonies, support on-call operations, evaluate technical solutions, and mentor engineers while maintaining quality, reliability, accessibility, and performance standards.

Lead architecture, development, and maintenance of WordPress delivery frameworks and website migrations using Gutenberg. Build custom themes, plugins, blocks, APIs, and reusable code while ensuring accessibility, performance, scalability, and testability. Support client websites, document implementations, and deliver user-facing features. Collaborate with designers, developers, project managers, and stakeholders using Agile methods. Provide technical leadership, knowledge sharing, and team training.

Develop and maintain production numerical software in Python for electromagnetic sensing systems. Architect APIs and integrations, optimize signal-processing code through vectorization, JIT, GPU acceleration, or compiled bindings, and establish testing and CI practices. Partner with signal-processing engineers to productionize algorithms from research and MATLAB prototypes. The role requires on-site work in Washington, D.C., periodic travel up to 30%, U.S. citizenship, and eligibility for a security clearance.

Develop and maintain Java, Python, JavaScript, and Oracle-based applications for Department of the Navy missions in classified and unclassified environments. Implement software enhancements, troubleshoot defects, optimize databases, support release pipelines, apply secure coding practices, and mitigate vulnerabilities. Research and develop AI capabilities using AWS services and modern frameworks. Collaborate with Agile teams, Government stakeholders, and auditors while supporting compliance and modernization initiatives.

Develop and maintain Java, Python, JavaScript, and Oracle applications supporting Department of the Navy missions. Responsibilities include full software development lifecycle delivery, secure coding, database performance optimization, vulnerability mitigation, release pipeline support, AI research and implementation, architecture modernization, troubleshooting, and audit compliance within an Agile Scrum environment.

Own Anthropic’s endpoint platform, including MDM infrastructure, macOS and mobile configuration as code, patching, zero-touch provisioning, telemetry, compliance controls, and automation. Operate the platform as a production service with observability, incident response, progressive rollouts, and rollback. Partner with Security, developer, and infrastructure teams on endpoint hardening and trusted-device access. Support Linux systems, document platform operations, and provide advanced escalation support.

Develops advanced digital signal processing algorithms for electromagnetic warfare and distributed spectrum sensing systems. Responsibilities include detecting, identifying, and tracking RF signals; processing recorded and synthetic I/Q data; integrating software with RF, SDR, and host-processing hardware; testing algorithms; and supporting field demonstrations. The role requires collaboration across engineering, production, and business development teams, on-site work in California or Washington, D.C., periodic travel, U.S. citizenship, and eligibility for a security clearance.

Develop advanced digital signal processing algorithms for RF signal detection, identification, tracking, classification, and geolocation. Integrate and test signal-processing software with RF, software-defined radio, and host-processing hardware. Work with recorded and synthetic I/Q data, support electromagnetic spectrum sensing, contribute to software integration and field demonstrations, and collaborate with business development, production, and engineering teams.

Serve as the technical anchor for a cross-functional engineering squad building healthcare data platforms. Design and maintain Java Spring Boot, React, and Python data-processing applications; guide architecture, code quality, estimation, releases, integrations, and issue resolution. Build reliable data delivery pipelines, mentor peers, support Agile execution, and promote responsible AI-assisted development using tools such as GitHub Copilot.

Design, build, and deploy web and database solutions using HTML, JavaScript, and Python within a healthcare context. Implement CI/CD and containerized deployments (OpenShift/Docker), integrate Red Hat Fuse ESB and Apache Camel, and architect AWS-based solutions (EC2, S3, Lambda, DynamoDB). Work in Agile teams, create/consume REST APIs, apply web security practices, and use tools like Jenkins/GitLab, GitHub, SonarQube, and Ansible.

Build and maintain backend services and metadata pipelines supporting data discovery, governance, and AI/ML workflows. Responsibilities include integrating relational databases, developing Java, Node.js, and Python services, optimizing distributed pipelines, implementing Terraform infrastructure, supporting GitLab CI/CD, and writing comprehensive tests. The role also involves troubleshooting scalability and reliability issues, designing asynchronous workflows, and collaborating on modern data lake, search, metadata, and LLM-enabled technologies.

Leads development of Python-based mission-planning and scheduling systems for spacecraft operations. Designs optimization algorithms, high-performance APIs, distributed services, and reliable production workflows. Improves scalability, observability, and operational resilience while collaborating across software, flight dynamics, satellite operations, product, and program teams. Provides technical leadership, mentors engineers, and applies automation and AI-assisted development practices.

Design, deploy, operate, and scale GPU/CPU infrastructure for Starshield’s national security missions. Manage Kubernetes and AI clusters, bare-metal and virtualized GPU platforms, operating systems, databases, monitoring, and distributed storage. Develop infrastructure automation, improve service reliability and performance, collaborate with AI engineers and customers, and lead technical excellence while mentoring junior engineers.

Own and improve cloud infrastructure, CI/CD pipelines, deployment tooling, monitoring, alerting, and incident response. Embed security and compliance controls for CJIS, CMMC, and SOC 2 requirements. Partner with engineering, security, product, and delivery teams to prioritize infrastructure work. Implement AI-driven DevOps automation, including remediation, anomaly detection, infrastructure-as-code generation, and compliance evidence collection.