Top Senior Python Jobs in Washington, DC

Supports large-scale global network operations and modernization for the U.S. Department of State. Responsibilities include enterprise network architecture, roadmap development, steady-state operations, cybersecurity integration, automation, monitoring, governance, lifecycle controls, implementation guidance, and telemetry-driven reporting. The role requires expertise in network infrastructure, cloud networking, SDN, SD-WAN, Zero Trust, government compliance frameworks, enterprise WiFi, ITSM integration, and infrastructure automation.

Define and lead Omnissa’s GTM Engineering function, including its roadmap, architecture, tools, and team growth. Build production-grade signal, enrichment, routing, scoring, and agentic workflow systems across Sales, Marketing, Customer Success, and RevOps. Own Clay and its integrations with Salesforce and other GTM platforms, measure business impact, manage vendors, improve data quality, and drive adoption globally.

Supports Juniper MX and Routing Director platforms in large-scale ISP and data center environments. Plans network deployments, develops implementation plans, tests solutions, troubleshoots hardware and software issues, manages JTAC cases, and delivers documentation, root-cause analyses, briefings, and training. The role requires advanced routing and switching expertise, customer-facing service delivery, network automation knowledge, U.S. citizenship, an active TS/SCI clearance with CI polygraph, and approximately 25% travel.

Lead the architecture and redesign of Axon’s multi-cloud networking stack across AWS, Azure, and devices. Define connectivity, reliability, security, performance, compliance, and cost strategies; guide production rollout and cross-team initiatives; identify risks; advise engineering leadership; mentor senior engineers; and establish engineering standards. The role also includes setting group-level AI strategy and using AI tools to accelerate software development.

Develop and operate mission-critical, cloud-based full-stack software for satellite tracking, analytics, radar orchestration, and data delivery. Responsibilities include building distributed backend services, designing APIs and message-driven workflows, ensuring reliability and security, participating in requirements discussions, supporting production systems and on-call rotations, and contributing to DOD/IC customer initiatives. The role also involves using generative AI and owning services throughout their development lifecycle.

Provides senior network engineering support for Juniper MX and Routing Director platforms in large-scale ISP and data center environments. Responsibilities include network deployment planning, implementation, testing, troubleshooting, customer support, JTAC case management, root cause analysis, documentation, and technical briefings. The role requires expertise in routing, switching, WAN transport, MPLS, VPNs, automation, and network operations, with remote work and customer-site travel.

Designs, architects, and leads delivery of enterprise applications, APIs, platforms, and AI-enabled solutions. Builds agentic workflows, LLM and RAG applications, integrations, data pipelines, and full-stack services across Azure and AWS. Establishes secure engineering, testing, CI/CD, observability, and reliability practices while addressing AI safety and governance. Partners with attorneys, product owners, AI and data teams, and executives to translate complex workflows into scalable solutions, lead architecture, mentor engineers, and drive initiatives from prototype through production.

Develop low-level embedded software and firmware for wearable smart optics systems. Responsibilities include board bring-up, Linux drivers, BSPs, Device Tree, DDR initialization, embedded Linux with Yocto, hardware-software debugging, and Python user-space tooling. Collaborate with electrical and mechanical engineers to build reliable, field-ready defense technology from prototype hardware.

Lead full-stack engineering workstreams for secure, accessible AI-enabled applications in financial services. Build TypeScript and React interfaces, Python or Node.js backends, human-review workflows, integrations, authentication, authorization, testing, and deployment pipelines. Collaborate with clients, AI and data specialists, risk teams, and vendors; mentor engineers; establish monitoring and support processes; and create reusable digital assets. The role requires direct client collaboration, technical leadership, and delivery of production applications.

Designs, builds, and maintains full-stack applications supporting federal defense planning and budgeting systems. Leads software architecture, testing, code reviews, mentoring, API integrations, CI/CD, security remediation, and defect resolution. Integrates LLM, RAG, and agentic AI capabilities into production systems while working across classified and unclassified environments. Requires extensive federal-sector software development experience, active Secret or Top Secret clearance, Security+ certification, and expertise with modern cloud, containerization, and software engineering technologies.

Develop and deploy full-stack, geospatial software solutions for strategic defense and security customers. Own the full lifecycle from discovery through delivery, integrate cloud infrastructure and CI/CD pipelines, translate customer challenges into technical requirements, identify reusable platform patterns, and use AI tooling for rapid iteration. The role involves customer collaboration, mentoring, code reviews, and supporting critical commitments while working hybrid in Arlington, Virginia, and traveling 30–50% to regional customer sites.

Lead the design and operation of a secure, reliable enterprise AI platform. Responsibilities include cloud infrastructure, shared runtimes, model access, deployment pipelines, observability, security controls, incident response, disaster recovery, readiness validation, and operational documentation. The role partners with AI, data, and forward-deployed engineering teams while monitoring platform availability, performance, token usage, and costs.

Deploys, configures, integrates, and operates Databricks and enterprise cloud data infrastructure for HUD. Automates infrastructure through IaC, scripting, APIs, and CI/CD; configures security, identity, access, compute, storage, and Unity Catalog. Supports data pipelines and Databricks applications, troubleshoots platform and integration issues, documents procedures, collaborates with cloud, cybersecurity, DevSecOps, and application teams, and provides technical leadership.

Design and implement scalable, noise-aware quantum circuit simulators (state-vector, tensor-network, stabilizer) and error‑correction pipelines. Integrate hardware-specific noise models, mid-circuit measurement and decoders, and optimize simulation pipelines for HPC, GPUs, or distributed systems. Collaborate with hardware and algorithm teams, prototype new simulation methods, and support performance estimation and business development.

Own enterprise Azure architecture for a federal agency, including landing zones, governance, networking, identity, security, migration, infrastructure as code, CI/CD, AKS operations, observability, and FinOps. Produce reference architectures and design documentation, lead architecture reviews, guide datacenter modernization, oversee engineers, present tradeoffs to senior leaders, and mentor technical staff. The hybrid role requires weekly onsite attendance in Washington, DC.

Lead technical onboarding and enablement for contact center partners, architecting scalable Zendesk, Amazon Connect, and AWS solutions. Provide co-selling support, technical strategy, solution design, demonstrations, proof-of-concepts, training, documentation, governance, and mentorship. Collaborate with partners, sales, engineering, and vendors to drive successful implementations, security compliance, innovation, and adoption of AI, automation, and omnichannel contact center technologies.

Develops and delivers resilient full-stack applications and services for Vantage’s reinsurance business. Responsibilities include application design, coding, debugging, testing, architecture discussions, risk management, roadmap estimation, stakeholder consultation, and coordination across project teams. The role promotes software engineering standards, DevSecOps, CI/CD, agile practices, innovation, and mentoring while building solutions with JavaScript, React, Node.js, Python, cloud, serverless, and modern infrastructure technologies.

Supports network deployment, integration, testing, commissioning, and troubleshooting for mission-critical FAA air traffic systems. Coordinates site readiness, telecommunications circuits, hardware installation, field teams, change control, documentation, and stakeholder communications. Provides remote and on-site technical guidance during cutovers and resolves infrastructure issues across federal operational environments.

Designs, assesses, and optimizes AWS C2S and GovCloud architectures for U.S. Coast Guard intelligence environments. Leads cloud migrations, modernization, right-sizing, security alignment, cost optimization, and target-state architecture documentation. Partners with ISSOs, engineers, project managers, and government stakeholders on controls, monitoring, roadmaps, briefings, and implementation. The role requires onsite work in Washington, DC on a hybrid schedule and an active Top Secret clearance with SCI eligibility.

Designs, builds, and maintains secure, scalable enterprise frontend applications and reusable UI components. Translates requirements into intuitive, accessible, high-performance interfaces; integrates frontend systems with backend APIs and data services; supports ETL and cloud-native application environments; and applies DevSecOps, automated testing, CI/CD, and secure coding practices. The role also mentors developers, establishes frontend standards, optimizes processes, and collaborates across teams.

Designs and operates secure, scalable cloud infrastructure for AI/ML workloads in classified, multi-enclave environments. Builds hybrid cloud and on-premises architectures, automates infrastructure with IaC and DevSecOps, manages Kubernetes and OpenShift platforms, integrates GPU and hyperconverged systems, and optimizes cloud networking, storage, databases, monitoring, security, and cost. Supports high-availability distributed training and inference applications while establishing technical standards and governance across teams.

Leads engineering teams supporting hybrid cloud architecture, automated data centers, multi-cloud environments, and Tier-3 infrastructure operations. Oversees DevSecOps adoption, Infrastructure as Code, automation, CI/CD, observability, security controls, and federal compliance with NIST, FISMA, and FedRAMP. Manages technical roadmaps, quality plans, service levels, stakeholder communications, hiring, mentoring, and operational reporting across mission-critical government environments.

Leads end-to-end software product engineering across complex programs, defining technical vision, architecture, roadmaps, and delivery practices. Develops full-stack Java/Python and Angular/React applications using SQL/NoSQL, AWS, microservices, APIs, streaming, CI/CD, and DevSecOps. Establishes engineering standards, performance and security practices, mentors engineers, oversees codebases, integrates AI capabilities, and communicates progress, risks, and tradeoffs to executives and cross-functional stakeholders.

Build and maintain full-stack web applications, interactive dashboards, backend integration services, resilient APIs, and AI-enabled features. Collaborate with engineering, data, product, and DevOps teams to integrate databases, automate deployments, troubleshoot cloud and hybrid environments, and scale enterprise application capabilities. Apply modern frontend, backend, DevOps, data visualization, and continuous delivery practices.

Build AI-powered tools, scalable services, APIs, automations, and community experiences for Brilliant Black Minds. Lead projects independently from design through release, integrate LLM capabilities, and manage community operations including Discord moderation, member engagement, and study groups. Serve as the program’s sole engineer while translating community needs into reliable technical solutions.