Top Senior Python Jobs in Washington, DC

As a Senior Site Reliability Engineer, you'll design and build complex systems, support Atlas platform operations, automate processes, and ensure high availability of services.

The role involves leading complex deployments of Deepgram's Voice AI platform for federal customers, managing the full technical lifecycle from discovery to production. Responsibilities include technical delivery, customer integration, and contributing to product development based on field feedback.

As a Forward Deployed Infrastructure Engineer, you will build, operate, and maintain scalable services, develop software solutions, automate workflows, and provide support for critical government software systems.

Design, deploy, operate, and scale GPU/CPU infrastructure for classified data centers and AI clusters. Build automation for on-premise Kubernetes clusters and operating systems, manage databases, monitoring, distributed storage, and GPU-as-a-service platforms, and improve service reliability. Collaborate with AI engineers, lead lifecycle operations, mentor junior engineers, and guide technical excellence across the team.

Own and ship major user-facing product features across search, dossiers, charts, maps, networks, dashboards, and mobile. Partner with design, product management, deployment teams, and users to build fast, intuitive, trustworthy experiences. Develop full-stack software using React and TypeScript alongside Python-based backend systems, while addressing distributed systems scalability, AI-assisted capabilities, latency, resilience, and reliable production deployment.

Designs, tests, and automates software delivery pipelines across development and production environments. Builds CI/CD processes, cloud-native solutions, infrastructure as code, monitoring, regression testing, and release automation. Troubleshoots pipeline failures and performance issues, collaborates with Agile development teams, and develops solutions across cloud platforms and technical stacks. The role requires eligibility for classified work and supports DevOps maturity in government cloud environments.

Designs and develops cloud architectures and applications across on-premises and public or private cloud environments. Implements infrastructure automation and DevSecOps practices, supports application migration, establishes secure and highly available cloud environments, and optimizes performance and cost. The role also develops PaaS, IaaS, SaaS, and DaaS delivery models, troubleshoots cloud stacks, manages monitoring and policies, and contributes to large-scale data and analytics initiatives.

Lead hands-on implementation of Celonis solutions for enterprise (federal) customers. Direct AI deployment agents to build data models, analyses, KPIs and operational solutions; validate AI outputs; run discovery and value workshops; ensure data connectivity; drive rollout, adoption, and handover; and develop domain-specific solution patterns to quantify business impact and sustainably scale process improvements.

Design, implement, and optimize cloud and edge software for mission-critical autonomous systems. Process heterogeneous sensor data for real-time state estimation and threat detection, integrate sensors and effectors, build LLM/AI-driven decision systems, and engineer scalable, reliable, fail-safe solutions for tactical and operational missions while collaborating with multidisciplinary teams.

Develop, integrate, and field autonomy capabilities for novel platforms (space, maritime, unmanned helicopters). Own end-to-end integration from software- and hardware-in-the-loop to live tests, partner with platform and cross-functional teams, support on-site testing, debug hardware/software issues, document designs, and improve integration and testing processes.

The role involves designing and building AI-native systems for revenue teams at Upside, including developing applications, partnering with teams, managing the entire stack, and improving system reliability and performance.

The Software Engineer will manage data collection for AI model training, optimize cloud infrastructure on GCP, and collaborate with scientists to enhance datasets.

Build and maintain scalable full-stack web applications using .NET, React, Next.js, and Azure. Responsibilities include feature delivery, API and microservices development, testing, code reviews, architecture, performance optimization, security, CI/CD support, cloud deployment, and production support. Senior engineers will mentor teammates and influence engineering standards, while early-career engineers receive mentorship and progressively greater ownership.

Design, build, and maintain secure, air-gapped cloud platform services and CI/CD pipelines for Okta Federal. Operate mission-critical infrastructure, monitor SLOs/SLIs, run incident response and POA&M remediation, and support Authority to Operate activities. Advocate SRE/DevOps practices across teams while working autonomously in secure facilities.

Defines system requirements and architectures, integrates software onto autonomous vehicles and defense systems, and deploys and validates robotics, sensor, perception, communication, and autonomy systems. The role includes field testing, simulation, troubleshooting, system modeling, cross-functional collaboration, and technical documentation in operationally challenging environments.

Develop Temporal workflows and Go services to automate cloud operations, build reliable SRE platforms, participate in on-call/incident response, debug distributed systems, and enable self-service through documentation and CI/CD automation.

Develop backend services and metadata pipelines for a data management and governance platform. Responsibilities include integrating relational databases, building REST services with Python, Java, and Node.js, implementing Terraform infrastructure, supporting containerized deployments and GitLab CI/CD, and writing comprehensive tests. The role also focuses on pipeline reliability, scalability, orchestration, observability, security, and AI/ML data workflows involving metadata, search, and LLM applications.

Administers hybrid Azure, AWS, and on-premises infrastructure, including servers, virtualization, networking, storage, identity, containers, and security. Develops automation with PowerShell, Python, and Terraform; manages Kubernetes and Docker environments; implements monitoring, AIOps, disaster recovery, and business continuity. Supports DevOps and DevSecOps practices, CI/CD pipelines, machine-learning-enabled infrastructure optimization, and security compliance while mentoring junior staff.

Develop and optimize enterprise database solutions, including complex SQL, stored procedures, data models, ETL processes, migrations, and automated deployments. Lead the transition from SQL Anywhere to SQL Server while supporting Oracle environments, troubleshooting production issues, and ensuring data integrity and security. Collaborate with application developers, DBAs, analysts, and QA engineers. Use AI-assisted development tools and support data pipelines for analytics and AI-enabled features.

Supports large-scale global network operations and modernization for the U.S. Department of State. Responsibilities include enterprise network architecture, roadmap development, steady-state operations, cybersecurity integration, automation, monitoring, governance, lifecycle controls, implementation guidance, and telemetry-driven reporting. The role requires expertise in network infrastructure, cloud networking, SDN, SD-WAN, Zero Trust, government compliance frameworks, enterprise WiFi, ITSM integration, and infrastructure automation.

Lead enterprise architecture and Java engineering teams developing scalable on-premises and AWS cloud applications. Design baseline and target architectures, optimize Oracle and PostgreSQL data systems, oversee CI/CD pipelines, and guide Agile and DevOps execution. Evaluate architecture gaps and recommend improvements for stability, interoperability, portability, scalability, and security accreditation. Provide technical strategy, client consultation, data analysis, project staff supervision, and leadership for national security missions.

Leads architecture and technical direction for national security enterprise applications. Designs and deploys scalable AWS cloud and AI solutions, develops software, manages CI/CD pipelines, and guides DevSecOps teams using Agile methodologies. Responsibilities include systems integration, technical analysis, infrastructure as code, vulnerability mitigation, troubleshooting, and support for ATO and security accreditation processes. The role collaborates with customers, senior stakeholders, program managers, and cross-functional engineering teams while mentoring technical personnel.

Leads physical implementation and layout of advanced-node D2D SerDes and analog/mixed-signal IP from floorplanning through tapeout and signoff. Owns matching-critical layout, parasitic control, integration, physical verification, reliability analysis, documentation, and production collateral. Collaborates with circuit, package, signal-integrity, ESD, CAD, foundry, and SoC teams while mentoring contributors and coordinating distributed partners. Develops analog layout automation and methodology improvements using scripting.

The Senior COTS Systems Administrator supports implementation, deployment, operations, maintenance, integration, and troubleshooting of a commercial physical access system. Responsibilities include coordinating networking, servers, virtualization, databases, identity services, APIs, and application integrations; supporting testing and production environments; maintaining technical documentation; assisting with accreditation and compliance; resolving issues; and communicating risks and status to stakeholders. The role is onsite at a government facility in Washington, D.C.

Designs, administers, and sustains virtual desktop and enterprise systems, with emphasis on user profiles, account administration, performance monitoring, security, troubleshooting, backups, operating systems, databases, storage, and virtualization. Provides Tier 1 and Tier 2 support, configures servers and applications, coordinates with network engineers, documents procedures, and remediates performance and cybersecurity risks. Occasional travel within the National Capital Region may be required.