Top Senior Python Jobs in Washington, DC

As a Forward Deployed Infrastructure Engineer, you will build, operate, and maintain scalable services, develop software solutions, automate workflows, and provide support for critical government software systems.

The role involves designing and building AI-native systems for revenue teams at Upside, including developing applications, partnering with teams, managing the entire stack, and improving system reliability and performance.

As a Solution Architect Senior Manager, you will lead software solution development, drive digital transformation, and oversee teams through complex projects while maintaining client relationships.

Lead full stack application migrations to AWS, architect solutions, mentor teams, and drive AI-native engineering strategy while ensuring cloud readiness and modernization.

The Manager, Solution Architect at PwC leads digital integration projects, focusing on cloud migration, AI-native development, and mentoring engineering teams while ensuring quality deliverables and strategic architecture design.

Lead software development and innovation efforts, mentor teams, manage projects and client relationships, and implement software solutions that drive digital transformation.

Maintain and improve multi-cloud Kubernetes infrastructure, CI/CD (Argo Workflows/ArgoCD), observability, and networking. Build reliable continuous deployment tooling and onboarding flows, provide internal support, collaborate across Platform Engineering, contribute upstream (open-source/operators), and participate in a 24/7 on-call rotation to resolve deployment infrastructure issues.

Serve as the technical lead modernizing mission-critical defense software: deploy and extend agentic modernization platforms, analyze large codebases, design scalable architectures, ensure RMF/NIST-compliant deployments, and deliver production-ready solutions in classified environments.

The role involves software development for a legacy web application, utilizing various programming languages and data engineering tasks for data migration, ensuring application integrity, and performance while collaborating with experts to refine requirements.

The Senior Full Stack Developer will design, develop, and maintain applications using Python and React, collaborating with teams to meet technical and business requirements.

The Solutions Architect will serve as a technical advisor, guiding customers through the integration and deployment of AI technology, with a focus on developing scalable architectures and ensuring successful adoption of Claude systems.

The Principal Software Engineer leads a team to develop full-stack real-time applications, integrates machine learning models, and influences software architecture in cloud environments while supporting healthcare analytics.

The Senior IT Systems Engineer will design, implement, and maintain IT systems, ensuring reliability and performance, while providing technical leadership and guidance.

As a Data Engineer, design and manage data pipelines, ensure data quality, optimize ETL processes, and support data integration for analytics workflows.

Design and develop web applications and ETL solutions, maintain existing packages, troubleshoot processes, collaborate with the team, and document requirements while ensuring quality and performance.

Develop and maintain cloud-based enterprise web applications using React, C#/.NET and/or Python. Build RESTful APIs, work with SQL Server/PostgreSQL, participate in CI/CD and Azure deployments, troubleshoot production issues, follow secure coding and accessibility standards, and collaborate on Agile teams.

Senior UI/UX Frontend Developer to design and implement responsive web applications, translate user needs into UI/UX solutions, create wireframes/prototypes, conduct user research, collaborate with product/design/engineering, support RESTful APIs, and enforce design standards. Hybrid role requiring TS/SCI with Polygraph and occasional SCIF visits in DC/VA/MD.

Design, deploy, and maintain cloud-hosted database solutions across AWS/Azure/GCP. Implement IaC for DB provisioning, optimize performance, ensure HA/DR and security compliance, troubleshoot incidents, support migrations, and collaborate with DevOps, application, and cybersecurity teams in a mission-focused federal environment.

Design, develop, and integrate real-time sensor fusion and perception algorithms across heterogeneous platforms and sensors. Deploy ML models and containerized solutions to embedded Linux devices, support DoD field tests, perform computer-/hardware-in-the-loop testing, and collaborate with tracking and autonomy teams to deliver and document robust autonomy solutions.

Design, build, test, and deploy full-stack web applications and REST APIs using FastAPI and React. Implement and maintain PostgreSQL schemas, containerized deployments with Docker on AWS, write tests, troubleshoot performance/security issues, and collaborate in a trunk-based workflow with code reviews and documentation.

Lead technical design, development, modernization, and deployment of enterprise web applications on Azure Government and Microsoft 365. Mentor teams, enforce standards, implement CI/CD and DevSecOps, migrate legacy systems, develop Python/ASP.NET backends and React frontends, manage databases (SQL Server/PostgreSQL), and ensure security/compliance (FISMA, NIST, ATO).

Design, implement, and secure scalable AWS cloud infrastructures; mentor junior engineers; automate deployments with IaC; enforce cloud governance and compliance; act as subject matter expert and participate in risk assessments.

Manage and automate infrastructure for on-prem and cloud deployments using infrastructure-as-code. Build, deploy, and operate services (containers, orchestration, fleet management), improve observability and availability, support security practices, and collaborate with cross-functional teams to scale and operationalize ML and web applications.

As a Forward Deployed Engineer, you will lead government AI model deployments, design full-stack systems, and ensure successful integrations and relationships with public sector stakeholders.

Lead solutions architecture for government clients, embedding with stakeholders to deploy GenAI solutions, and ensuring project success through prototype development and technical guidance.