Top Senior Machine Learning Jobs in Washington, DC

Own strategic partnerships with CPG customers, driving measurable outcomes, platform adoption, user expansion, and retention. Analyze usage data and business context to identify risks and opportunities, develop success plans, lead executive and operational relationships, and advocate for customers internally. Collaborate with product, sales, marketing, and support teams while contributing to repeatable playbooks, thought leadership, and customer best practices.

Conduct applied research on scalable optimization and resource-allocation algorithms for large communication networks. Apply machine learning, reinforcement learning, integer optimization, graph-based methods, and metaheuristics to improve solution quality and efficiency. Collaborate with software engineers to integrate algorithms into production aerospace networking systems, evaluate performance at realistic scale, publish research, support patent applications, and document novel methods.

Manage the operational integrity of an automated group health insurance underwriting workflow. Review and approve RFPs, validate broker and external data, correct errors, monitor funnel and risk metrics, analyze quote-to-bind performance, triage inquiries, coordinate with sales and health plan operations, and maintain underwriting dashboards and reporting.

Lead AI agent optimization efforts by designing systems that improve token efficiency, response time, reliability, and output quality. Build agentic coding systems, develop AI application patterns, own features end to end, collaborate with engineering and field teams, support the developer community, and create public technical documentation. Work across Python, TypeScript, Java, and Go while serving as a domain expert in agent design and optimization.

Design and productionize machine learning, deep learning, LLM, personalization, recommendation, search, and retrieval systems. Collaborate with product, engineering, and analytics teams to deploy AI solutions that improve customer experiences, business growth, and operational efficiency. The role requires driving projects from ideation through deployment and delivering measurable business impact in a fast-moving fintech environment.

Lead development of model-driven pricing intelligence, supplier performance signals, and automated financial reconciliation across flights, hotels, cars, and ancillaries. Define roadmaps, productionize predictive models, implement monitoring/drift detection, and deliver cross-functional, measurable systems that ensure revenue integrity and marketplace economics.

The Chief Enterprise Architect will oversee the design and integration of cloud and data architecture solutions for government projects, ensuring alignment with industry standards and best practices.

Leads AI/ML engineering teams across platform and delivery pods, managing employees and contractors while enforcing code, agent, review, and production-readiness standards. Partners on reusable templates, pipelines, and evaluation processes, ensures adoption across teams, manages contractor performance and conversion, and removes delivery blockers. The role requires hands-on credibility reviewing agent architectures, prompts, and evaluation suites, with experience operating as a player-coach in fast-moving organizations.

Develop and optimize machine learning and statistical models for fraud detection and anti-money laundering. Analyze large datasets to identify fraudulent patterns, build scalable data pipelines and features, evaluate model performance, and collaborate with engineering, product, and operations teams. Communicate insights to technical and non-technical stakeholders while maintaining data privacy and security compliance. The role offers significant ownership in building Oscilar’s early machine learning stack within a remote-first startup.

Own LanceDB’s product direction by shaping the roadmap with technical leadership, researching users and competitors, gathering continuous user insight, and driving cross-functional prioritization. The role partners closely with engineering as a technically respected peer, defines product changes for AI and data-platform users, uses metrics and experiments to guide decisions, and operates with high ownership in an ambiguous environment.

Advise enterprise clients on AI and data strategies, transformation roadmaps, operating models, governance, privacy, technology rationalization, and business cases. Lead discovery workshops, executive engagements, and art-of-the-possible sessions; prioritize use cases and connect technical recommendations to business outcomes. Build the advisory practice, develop offerings, manage multidisciplinary teams, mentor staff, strengthen client and partner relationships, and support successful distributed project delivery.

Designs and maintains high-volume HL7 and FHIR ingestion pipelines, secure Epic and hospital integrations, data validation systems, and compliant healthcare data exchanges. Builds enterprise SaaS microservices using ReactJS, Python, and AWS services; optimizes distributed and hybrid-cloud environments; leads testing, code reviews, production troubleshooting, architecture documentation, and customer communications. Preferred experience includes Epic App Orchard, healthcare integration engines, clinical workflows, GenAI/ML, DevOps, data pipelines, and NoSQL.

Tune AML and fraud detection models using customers’ live transaction data. Investigate missed cases, alert quality, pattern drift, and false positives; validate changes through backtesting and sample review; document regulatory rationale; and present model performance and business value to compliance, risk, and data science stakeholders. Partner with customer teams on account strategy and relay customer-specific or systemic findings to product and model functions.

Drive net-new enterprise customer acquisition from lead generation through contract closure. Build C-level relationships, develop account strategies, manage CRM pipelines and forecasts, negotiate complex contracts, and close large AI, machine learning, and data talent engagements. Partner with marketing, customer success, and talent teams to deliver customer outcomes and expand Factored AI’s enterprise footprint.

Lead data science for defense clients: perform data engineering, mining, exploratory/predictive/statistical analysis; build ML/AI tools (recommendation engines, automated scoring); manage large, disparate data sources using R/Python/SQL; create visualizations in Power BI/Tableau; support Multi-INT analytics and provide senior-level analytic products for the defense cover program.

Lead architecture and design of cybersecurity solutions for federal networks, focusing on hardening systems, reducing attack surface, Zero Trust, cloud and IoT security, A&O, identity and access management, product selection, and guiding senior leaders to mature cybersecurity capabilities.

Develop and deploy predictive and causal models for personalization, retention, monetization, and product strategy. Design experimentation and measurement frameworks, analyze user and marketing behavior, quantify business impact, and translate complex findings into strategic decisions. Collaborate with Product, Engineering, Marketing, and Data Product teams to build scalable data solutions. Mentor peers, promote rigorous model validation and governance, and apply Python, SQL, Snowflake, dbt, Airflow, Spark, and AWS to production-ready data science initiatives.

Lead the design and implementation of large-scale AI and machine learning systems for Yahoo Search across multiple teams. Define data strategies, evaluation frameworks, and scalable production-serving approaches. Drive technical alignment among engineering, product, design, and research teams; guide adoption of large language models, vision models, generative AI, and agentic AI; and oversee data analysis informing strategic product decisions.

Drive enterprise sales growth across North American banking, credit card, and financial services accounts. Develop strategic account and business development plans, build customer and partner relationships, close complex multi-million-dollar technology deals, and engage C-level stakeholders. Represent the company at industry events, collaborate with commercial and leadership teams, manage pipeline forecasting and reporting, and apply MEDDPICC methodology. The role focuses on cybersecurity, fraud prevention, authentication, and SaaS or cloud solutions, with 50% domestic and international travel.

Lead client-facing finance transformation engagements to optimize finance functions through operating model design, process improvement, automation and AI. Manage project teams and client relationships, deliver high-quality recommendations and tools, identify value-creation opportunities across G&A, support business development, and coach junior staff.

Lead complex analytics projects for DoD/intelligence customers by developing and evaluating analytic methodologies, designing domain ontologies and knowledge graphs, applying semantic web standards, enabling semantic data retrieval and reasoning, integrating diverse data sources for interoperability, and guiding teams to produce actionable intelligence.

Own the technical side of deal progression for airline deployments: qualify opportunities, run demos and POCs, author integration and deployment architectures (PSS, APIs, data feeds, DNS, identity, networking), respond to RFPs/security questionnaires, scope SOWs and NFRs, and build reusable demo/reference assets to drive adoption and expansion while liaising between sales, engineering, and customers.

Lead the design, development, deployment, and governance of advanced analytics, machine learning, and AI solutions using large healthcare datasets. Responsibilities include data preparation, statistical and predictive modeling, model monitoring, explainability, visualization, stakeholder communication, and translating findings into clinical and operational improvements. The role also mentors data professionals, advises leaders, manages initiative priorities and risks, and promotes responsible AI and Agile practices.

Leads enterprise IAM strategy for public cloud, SaaS, generative AI, machine learning, and agentic AI environments. Defines governance, standards, controls, roadmaps, and identity-security patterns; assesses cloud and vendor solutions; evaluates human and non-human identity risks; and advises on least privilege, authorization, secrets, and entitlement governance. Partners with technology, risk, compliance, audit, and executive stakeholders to identify gaps, guide modernization, and communicate strategic recommendations.

You will tackle AI challenges, develop scalable software and collaborate with teams to enhance healthcare navigation using AI solutions.