Top Senior Machine Learning Jobs in Washington, DC

Leads enterprise advanced analytics and modeling to identify drivers of business performance across brands, markets, customers, accounts, and geographies. Translates findings into prioritized actions, playbooks, launch strategies, and scenario-based recommendations. Oversees rigorous, scalable analytical approaches, partners with senior stakeholders, and develops analytics talent across the organization.

Lead analyst relations programs to improve Databricks’ positioning in industry evaluations, including Gartner, Forrester, and IDC. Develop differentiated narratives, submissions, demonstrations, customer evidence, and executive briefings. Scale analyst relations through AI-assisted workflows, convert analyst feedback into product and go-to-market recommendations, and influence product, marketing, sales, and executive teams. Manage multiple deadline-driven workstreams while improving analyst advocacy, market visibility, and evaluation outcomes.

Develop and support scalable Python services, APIs, and event-driven systems for digital freight pricing and booking. Build experimentation frameworks, AI-assisted pricing harnesses, validation guardrails, real-time platforms, and machine-learning integrations. Lead architecture decisions, ensure security and reliability, mentor engineers, and collaborate across product, operations, revenue management, data science, and engineering teams.

Own the commercial success of a portfolio of strategic enterprise accounts, including renewals, retention, expansion revenue, forecasting, and multi-year account strategies. Build executive relationships, lead business reviews and complex negotiations, coordinate cross-functional resolution efforts, and represent client needs internally. Mentor other Account Managers and use generative AI tools for account planning and communications while protecting confidential information.

Owns strategy, roadmaps, backlogs, and end-to-end delivery for business automation and AI products. Partners with engineering and executives to define requirements, launch reliable features, evaluate build-versus-buy decisions, manage budgets and cloud/API costs, measure ROI, and maintain product performance. Requires strong technical, agile delivery, analytics, and healthcare privacy expertise, with potential progression into product management leadership.

Lead the vision, strategy, and roadmap for ADAPT, a roadway and right-of-way asset management platform for public agencies. Partner with engineering, design, data science, and go-to-market teams to deliver reliable, customer-focused features, including AI capabilities. Define product quality standards, metrics, enterprise requirements, and launch strategies while validating solutions with clients and balancing feature development with scalability, security, and reliability.

Define and scale autonomous agricultural machinery products through customer research, experimentation, roadmap prioritization, system requirements, and cross-functional delivery. Partner with engineering and commercial teams on hardware, embedded software, computer vision, machine learning, navigation, controls, and mobile solutions. Use data, field feedback, and performance metrics to improve adoption, customer confidence, mission quality, and product impact.

Own enterprise sales across new and existing accounts, leading consultative, ROI-driven sales cycles from discovery through close. Develop account plans, build executive relationships, collaborate with Solutions and Forward Deployed Engineers, forecast pipeline, maintain CRM discipline, lead business reviews, represent the company at industry events, and relay customer insights to shape the product roadmap.

Develop graduate-level Applied AI course materials, including lessons, labs, case studies, assignments, rubrics, projects, readings, templates, and videos. Design practical activities using LLMs, RAG, AI agents, automation, APIs, and evaluation tools. Collaborate with learning designers and university faculty, explain complex concepts to nontechnical learners, maintain academic quality, and update content as AI tools and regulations evolve.

Build and deploy production software and AI services, including APIs, UIs, ML pipelines, and agentic evaluators. Design scalable cloud architectures, maintain full-stack deployments, and apply AI technologies to solve complex customer problems. Collaborate with engineers, product teams, customers, partners, and executives to gather requirements, deliver solutions, and drive consensus. The role also involves prototyping, shipping releases, field debugging, stakeholder management, mentoring, and continuous learning.

Leads AML transaction monitoring optimization, including rule testing, threshold tuning, scenario design, and alert reduction. Drives FIU automation and workflow improvements, evaluates AI-enabled compliance tools, and partners with Product, Engineering, Data, Operations, and vendors on monitoring infrastructure and integrations. Supports scalable compliance controls across new products, jurisdictions, and transaction volumes while maintaining regulatory alignment and detection effectiveness.

Manage enterprise metadata, business glossaries, data catalogs, and end-to-end data lineage for a federal case management modernization program. Configure governance and metadata platforms, integrate data sources and pipelines, establish standards and workflows, monitor metadata quality, support compliant data sharing, develop governance metrics, document procedures, and train data stewards and business users.

Develops data quality checks, metadata standards, and AI use-case inventories for HHS. Cleans and integrates complex datasets, applies machine learning and NLP for automated tagging and classification, evaluates AI governance risks, and produces reporting datasets, dashboards, and recommendations. The role requires translating ambiguous federal policy and reporting requirements into repeatable analytical workflows while collaborating with product, design, engineering, and government stakeholders.

Develop and deploy machine learning and LLM-based solutions for cybersecurity challenges. Responsibilities include analyzing complex datasets, building classification and NLP models, optimizing prompting, embeddings, RAG, and fine-tuning techniques, designing evaluation methodologies, and integrating models into scalable production systems. The role requires collaboration with cybersecurity researchers, software engineers, data engineers, and product managers.

Own the authorization optimization product roadmap, improving legitimate transaction approval rates and recovered merchant revenue. Define technical requirements, APIs, data models, integrations, and issuer-specific decisioning strategies. Partner with engineering, data science, sales, solutions, and customer success to deliver fraud-aware authorization improvements involving retries, 3DS, decline recovery, and payment routing. Manage partnerships with payment ecosystem providers, quantify opportunities using issuer and BIN intelligence, and communicate product strategy and performance to stakeholders.

Leads the design, implementation, and support of complex, scalable software components and distributed systems. Provides technical leadership through architecture decisions, mentoring, code and design reviews, troubleshooting, and engineering standards. Partners with product, quality, architecture, and DevOps teams on secure cloud-native solutions, CI/CD, observability, performance, releases, and platform modernization. Participates in hiring and communicates technical risks and tradeoffs to stakeholders.

Leads biostatistical activities for Phase II–III clinical trials, from protocol design through reporting and regulatory submission support. Responsibilities include statistical analysis planning, sample size calculations, SAP development, TLF review, database lock support, safety reporting, regulatory responses, and oversight of programming or CRO work. Collaborates with cross-functional clinical teams and uses SAS or R for analyses, modeling, simulation, exploratory work, and quality control. Coordinates statistical activities across studies and applies advanced statistical and machine learning methods.

Leads statistical activities for Phase II–III clinical trials from protocol design through reporting and regulatory submissions. Develops statistical analysis plans, sample-size calculations, and reviews tables, listings, and figures. Oversees internal programmers and CRO contributions, applies SAS and R for analyses and quality control, and collaborates with clinical, data management, programming, and regulatory stakeholders. Coordinates statistical activities across studies and applies advanced statistical, machine learning, and modeling methods to support drug development.

Develop and standardize analytical methods for inferring residence, displacement, and poverty from mobile network operator data. Assess data quality, write technical specifications and tests, guide operator engineering teams, tune statistical methods, and balance accuracy with implementation constraints. Design privacy-preserving analyses, improve data security practices, train internal teams, and support international workshops and emergency-response programs.

Resolve complex customer technical issues across Linux, networking, security, Kubernetes, cloud, storage, and ML environments. Diagnose problems, automate workflows with Python and Bash, support model deployment and inference pipelines, communicate resolutions, escalate unresolved issues, and maintain troubleshooting documentation. The role requires rotational shifts or on-call availability and remote work in the USA.

Senior cheminformatics professional responsible for building and maintaining scalable chemical databases, search systems, indexing, similarity analysis, and analytics workflows. The role develops agentic AI solutions for drug and pipeline analysis, integrates scientific literature with computational tools, and applies machine learning to pharmaceutical research and market analytics. Candidates need advanced chemistry or related scientific education, cheminformatics expertise, pharmaceutical or biotech experience, and strong interdisciplinary communication skills.

Develop and own advanced machine learning and AI models using bank transaction and cashflow data to enable financial product capabilities, manage risk, and drive profitable growth. Design experiments, build proofs of concept, monitor production models, and collaborate with data and machine learning engineering teams on scalability. Communicate findings and tradeoffs to business stakeholders while applying statistical, research, and financial services expertise.

Own the strategy, roadmap, architecture, performance, and business outcomes of Versapay’s global payment gateway. Lead processor and acquirer integrations, transaction lifecycle capabilities, compliance, reliability, and payment optimization. Partner with engineering, finance, risk, compliance, operations, and go-to-market teams while guiding execution across engineering pods. Apply AI and machine learning to retry optimization, decline analysis, anomaly detection, incident response, and partner integrations.

Develop AI agents, chatbots, and machine learning models for a modernized federal data science platform. Research and standardize AI capabilities in Databricks and Palantir, prompt-engineer LLMs, integrate AI into DevOps pipelines, and train models on production datasets for prediction and anomaly detection. The role requires collaboration with developers and customers, database familiarity, Agile experience, documentation, and an active or obtainable DoD Secret clearance.

Lead computational platform development for biological design, optimization, and functional prediction. Collaborate with wet-lab scientists to validate predictions, oversee data infrastructure and computational workflows, and contribute to technology roadmaps, funding proposals, and partnerships. The role requires developing machine learning methods for biological sequence and structure analysis, translating biological problems into computational solutions, and leading technical teams across computational and experimental disciplines.