Top Python Jobs in San Diego, CA

Leads system-level verification and validation for complex sequencing platforms from development through launch. Develops test strategies, plans, fixtures, instrumentation, and automated test infrastructure; evaluates performance, reliability, thermal control, and operating margins. Applies DOE, statistical analysis, troubleshooting, and root cause analysis to resolve issues. Partners with multidisciplinary engineering, quality, manufacturing, and operations teams, communicates technical risks and recommendations, drives continuous improvement, and mentors engineers.

Develop and maintain microservices and full-stack web applications using Java, C++, Python, and cloud technologies. Apply Agile, DevSecOps, CI/CD, GitLab, and automated testing practices. Support cloud development environments, unit and integration testing, technical leadership, mentoring, task direction, work-product reviews, customer collaboration, and training-material development. This is an on-site role supporting space and intelligence systems in Boulder, Colorado.

Manage software configuration processes, release schedules, builds, deployments, repositories, and configuration control boards for a DoD program. Coordinate with development, QA, administrators, and customers to resolve issues, maintain tools and documentation, support VHDL repositories, administer collaboration platforms, and troubleshoot system problems. The role requires strong communication, scripting, database, software build, and configuration management expertise, along with an active Secret clearance.

Develop Java-based microservices and full-stack web applications using Java, C++, Python, and cloud technologies. Apply Agile, DevSecOps, CI/CD, GitLab, unit testing, and integration testing practices. Support cloud development environment configuration, mentor junior engineers, provide technical direction, review work products, collaborate with customers and multidisciplinary teams, and maintain training materials.

Conduct preliminary design, performance analysis, and sizing of advanced manned and unmanned aircraft. Develop and document technical solutions, brief customers, guide design teams, support proposals and business development, and analyze mission, aerodynamic, propulsion, maneuvering, takeoff, and landing performance. The role supports government programs and requires active Secret clearance, Special Program Access eligibility, and travel.

Join an agile team to design, develop, test, and deploy secure enterprise software. Participate in SAFe ceremonies, apply software engineering principles, build automation scripts, promote code reuse, and support the full lifecycle in secure environments.

Integrate, modify, test, and maintain mission systems software across the full software development lifecycle. Responsibilities include requirements development, architecture, implementation, hardware-software integration, verification, qualification, deployment, and maintenance. The role supports Agile Scrum teams developing safety-critical embedded real-time software and requires collaboration with systems, hardware, and test engineers. Candidates need experience with C, C++, or Python, RTOS environments, RHEL, software testing, and government clearance requirements.

Lead trajectory prediction and aircraft-response modeling for safety-critical runtime assurance systems. Develop and validate models using Python, simulation, hardware-in-the-loop, and flight-test data. Integrate trajectory behavior with autopilot interfaces, analyze vehicle-state and telemetry data, support flight-test campaigns, and contribute to C/C++ implementation, testing, and debugging. Coordinate with algorithms, software, systems, test, and platform teams while producing validation evidence and algorithm handoff artifacts.

Provides technical leadership for automated testing and verification across autonomy software, machine learning systems, distributed services, simulation environments, hardware-in-the-loop platforms, and GPU infrastructure. Owns test architecture, MLOps quality, CI/CD and continuous training workflows, ML validation, observability, failure triage, scenario-based testing, and scalable Python automation. Collaborates across software, autonomy, data, simulation, and systems engineering teams while governing AI-assisted testing workflows.

Develop and integrate safety-critical Run-Time Assurance software for autonomous aircraft. Responsibilities include modern C++ development, real-time embedded systems, hardware and simulation integration, HIL and flight testing, interface design, testing, CI, static and dynamic analysis, documentation, traceability, and collaboration across software, systems, test, and platform teams.

Integrate and verify autonomy software on aircraft hardware across SIL, HIL, ground, and flight-test environments. Develop test plans, test cards, schedules, and automation; identify and resolve interface, timing, protocol, and hardware/software integration gaps. Coordinate with aircraft vendors, configure test benches, troubleshoot anomalies, assess flight readiness, and analyze post-flight data. The role requires Linux and Python proficiency, cross-functional coordination, periodic travel, and eligibility for a U.S. DoD SECRET clearance.

Performs structural analysis and testing for advanced UAV airframes and components. Builds finite element models, conducts static, modal, fatigue, vibration, and shock analyses, validates results through hand calculations, and analyzes telemetry and test data. Collaborates with engineering teams to optimize lightweight composite and metallic structures for strength, weight, safety, and manufacturability. Documents technical findings and supports structural test planning, certification, and continuous improvement of analysis methods.

Develop and lead systems modeling and simulation analyses for weapon-system product support. Responsibilities include spares and readiness forecasting, obsolescence forecasting, level-of-repair analysis, cost and business-case analysis, and cost-per-flight-hour analysis. The role manages technical teams, develops models, performs data analytics, supports requirements development, presents findings to leadership, and uses simulation, optimization, regression, and trend analysis techniques.

Provides technical leadership for RF and digital hardware sustainment supporting F-22 systems. Defines test strategies, leads root-cause investigations, analyzes performance and yield data, improves test methods and equipment, and coordinates hardware/software integration. Mentors engineers and technicians, supports maintenance and field locations, and aligns sustainment priorities with program objectives. The role is full-time onsite in San Diego, requires an active Secret clearance and ability to obtain Top Secret clearance, and involves travel up to 25%.

Evaluate AI coding-agent interactions for usefulness, correctness, engineering judgment, reasoning quality, and developer trust. Provide clear, opinionated feedback, distinguish response-quality levels, and help define standards for excellent interactions with tools such as OpenAI Codex, Claude Code, and Cursor. This contract role requires staff- or principal-level software engineering experience and familiarity with modern AI-assisted development workflows.

Designs, implements, and maintains CI/CD pipelines, GitOps workflows, Kubernetes infrastructure, and automated software deployment systems across on-premises and public cloud environments. Manages containerization, infrastructure as code, observability, security scanning, API deployment automation, and developer tooling. Collaborates with development and operations teams, recommends technology improvements, documents processes, and trains IT staff. The role is fully onsite in San Diego and requires up to 10% domestic travel.

Develop and maintain C++ and Python software for distributed, hard- and soft-real-time control systems. Responsibilities include designing modular solutions, integrating complex hardware and communication protocols, conducting unit and on-target testing, evaluating technical risks, gathering requirements, and supporting the full software development lifecycle. The role involves collaboration with architects and cross-functional engineers, continuous process improvement, and potential AI integration. Work is primarily onsite in San Diego and may require cleanroom access.

Develop MBSE artifacts, technical requirements, system models, interfaces, specifications, and verification plans for aerospace modernization and sustainment programs. Collaborate across integrated product teams, engineering disciplines, stakeholders, and customers; maintain configuration-controlled systems engineering artifacts; and communicate technical analyses and recommendations. The role requires Secret and SAP clearance eligibility, requirements management experience, Python or scripting, DOORS, and MBSE expertise.

Build and operate Kubernetes-native platform services and distributed orchestration capabilities supporting AI workloads across cloud, on-premises, edge, sovereign, and air-gapped environments. Design production software, data-processing infrastructure, observability, deployment patterns, and operational standards. Establish reference architectures, reliability practices, benchmarks, and recovery procedures while partnering with autonomy, ML, simulation, infrastructure, and product teams. Provide hands-on technical leadership in distributed systems architecture, implementation, troubleshooting, performance analysis, and platform reliability.

Lead validation and end-to-end integration testing for proprietary and third-party software. Deploy applications and containerized microservices in Linux, Docker/Podman, and Kubernetes environments; validate APIs, data flows, and backend changes; automate checks with Python and Bash; troubleshoot configuration and deployment issues; document defects and coordinate resolutions with vendors, engineers, and product managers.

Leads and mentors engineers developing, integrating, testing, deploying, and operating complex DoD software and hardware systems. Defines requirements, architects solutions, manages program execution, troubleshoots system and network issues, and coordinates field test events. The role works directly with Navy warfighters, test directors, and government sponsors while ensuring quality, cost, schedule, and operational objectives. Travel up to 25% is required, along with eligibility to obtain and maintain an active Secret clearance.

Designs, develops, tests, and maintains Python-based APIs, backend services, data platforms, and AI-ready data foundations. Builds scalable and secure FastAPI and SQL solutions, supports cloud-native integrations, CI/CD, observability, testing, deployment automation, and production operations. Collaborates with product, AI, application, architecture, reliability, and security teams in an agile environment to deliver maintainable platform capabilities.

Leads software teams developing, integrating, deploying, and maintaining full-stack mission applications for DoD and intelligence customers. Builds prototypes and high-performance user interfaces, translates operator needs into features, integrates systems, and conducts deployment and field testing in secure operational environments. The role combines customer collaboration, product discovery, engineering leadership, and software delivery in high-security settings.

Develop Palantir Foundry ontology, applications, workflows, and data pipelines for defense clients. Integrate data engineering, analytics, AI/ML models, and technology solutions; translate stakeholder requirements into technical implementations; collaborate with Agile teams; conduct code reviews; and apply DevSecOps, CI/CD, and infrastructure automation practices. The role supports mission-focused data exploration and analytics while requiring eligibility for Secret clearance.

Designs, integrates, configures, and sustains secure network and computing infrastructure across on-premises, cloud, edge, and distributed environments. Responsibilities include Layer 2/3 networking, troubleshooting, hardware and software integration, installations, upgrades, inventory management, technical documentation, cybersecurity implementation, and coordination of engineering teams. The role supports hybrid infrastructure, network security, cloud networking, containerized environments, automation, and mission-critical government systems.