Top Python Jobs in San Diego, CA

Leads systems engineering across compute, camera, and radio portfolios, including requirements development, architecture, interface definition, integration, verification, qualification, testing, and lifecycle oversight. Coordinates technical teams, develops specifications and test plans, performs trade studies, and ensures customer requirements are satisfied. The role requires embedded software, flight and ground systems, processor, communications protocol, and technical leadership experience.

Develops and delivers systems engineering products for aerospace programs. Responsibilities include requirements development and allocation, verification and validation planning, interface definition, technical documentation, configuration management, stakeholder coordination, and support across integrated product teams. The role requires collaboration with technical and non-technical audiences, scripting experience, and an active Secret clearance, with potential access to Special Access Programs.

Designs, develops, tests, and debugs embedded software for satellite systems. Responsibilities include bootloaders, board support packages, device drivers, embedded operating systems, hardware integration, verification planning, and architectural leadership. The role requires solving complex low-level software problems, developing test programs, improving engineering processes, and collaborating cross-functionally. Key expertise includes C, Python, VxWorks, Embedded Linux, RTEMS, Buildroot, Yocto Linux, NAND flash file systems, and laboratory debugging equipment.

Design and implement control plane software spanning SDN, ground systems, satellites, and terminals. Build scalable services and APIs for provisioning, configuration, automation, telemetry, and network operations. Address dynamic network conditions and integrate with cloud and on-premises platforms. Collaborate across data plane, platform, embedded systems, product, and quality teams while contributing to architecture, implementation, testing, debugging, and system integration.

Develop and maintain software configuration management, release engineering, build, deployment, and version-control processes for DoD software programs. Support ClearCase, ClearQuest, Jira, GitHub, scripting, databases, build environments, release schedules, configuration control boards, and platform integration builds. Troubleshoot system and deployment issues, automate productivity tools, maintain documentation and standards, administer related repositories and SharePoint structures, and coordinate with developers, QA, administrators, vendors, and customers.

Build and operate a large-scale software factory for software teams. Integrate and automate continuous build, integration, testing, and deployment pipelines. Collaborate with software teams, chief engineers, and IPTs in an on-site, fast-paced environment. Apply full SDLC and Agile practices to embedded software integration and testing, using C, C++, Python, and DevSecOps tools. Travel up to 25% may be required.

Designs, deploys, supports, and optimizes network infrastructure for avionics integration systems. Responsibilities include configuring routers, switches, and firewalls; troubleshooting complex network issues; developing automated data center deployments; maintaining documentation and standards; supporting software integration labs; and collaborating with engineering and technical teams. The role is full-time onsite, requires a security clearance, and involves up to 25% travel.

Lead technical strategy and implementation of V-BAT fleet data analysis pipelines and tooling. Transform raw flight, simulation, and production data into metrics, dashboards, and reports; perform fleet-wide studies, anomaly investigations, and root-cause analysis; partner with cross-functional teams and mentor engineers on analysis best practices.

Leads a 10–20-person software engineering team through the full SDLC in an Agile environment. Manages work-package planning, product delivery, contractual cost and schedule requirements, Agile metrics, EVMS reporting, risks, and mission objectives. Provides technical direction, mentoring, functional management, staffing, interviewing, onboarding, and performance support. The role requires on-site work in San Diego or El Segundo, up to 25% travel, and Top Secret and SAP access.

Leads systems engineering for a scientific instrument platform, owning system architecture, technical budgets, requirements, verification and validation, risk management, reliability, controls, and design transfer to manufacturing. Builds and manages the systems engineering function, guides product roadmaps, oversees suppliers and contract manufacturers, drives cost reduction and quality improvements, and ensures platform performance across hardware, consumables, assays, software, and analysis.

Designs, builds, and evolves scalable, secure, reliable cloud platform capabilities. The role focuses on infrastructure automation, reusable self-service solutions, CI/CD, container orchestration, cloud security, governance, cost optimization, and developer experience. It also involves setting engineering standards, solving complex technical challenges, influencing technical direction, collaborating across teams, and mentoring engineers in an enterprise environment.

Own and maintain test hardware, equipment, and programs for analog/mixed-signal IC production. Perform bench validation, DAC characterization, PCB debugging, data analysis, and documentation. Collaborate with hardware/firmware and applications teams to improve EVMs, reduce test time, support GR&R and correlation, and assist customer deployments and silicon validation.

Lead NPI from first silicon to high-volume manufacturing for precision analog and mixed-signal ICs. Develop and optimize wafer sort and final test solutions (Teradyne UltraFlex IGXL), correlate bench and ATE results, establish production limits, design/validate test hardware (load boards, probe cards, sockets), perform silicon debug/root-cause analysis, support qualification and transfer to OSAT, and create automation tools using Python and JMP to improve throughput and quality.

Develop distributed computing algorithms, performance metrics, and analysis tools for Zoox’s Collision Avoidance System. Analyze petabytes of urban driving data, evaluate system performance, and collaborate with CAS Perception, Planning, Systems Design, Mission Assurance, and QA engineers to define autonomous-driving validation metrics and plans.

Leads software engineering teams within an Agile Integrated Product Team, managing technical commitments and full SDLC delivery. Develops, integrates, tests, and documents embedded, object-oriented software using languages such as C, C++, Java, and Python. The role involves software architecture, real-time and mission-critical systems, Agile leadership, and collaboration across employee and management levels. This is a full-time onsite position in San Diego or El Segundo, with travel up to 25% and an active Top Secret clearance required.

Designs and simulates FPGA/modem systems using Ultrascale+ and Versal platforms. Develops VHDL and SystemVerilog designs, works with high-speed SerDes and communication interfaces, and uses scripting languages for development and automation. The role requires extensive FPGA experience and offers contract-to-permanent potential. Software-defined radio/modem, PetaLinux, RF design, encryption, and active government clearance experience are preferred.

Lead development of autonomy capabilities for space platforms including distributed optimization, tasking/scheduling, track fusion, RPO and motion planning. Build high-performance, well-tested software, integrate on real vehicles, support deployments and testing, and research/roadmap advanced autonomy techniques for defense applications.

Lead development of space autonomy capabilities including distributed optimization, tasking/scheduling, track fusion, rendezvous/RPO, and motion/behavior planning. Build high-performance, testable software, integrate and validate on real platforms, support deployments, and mentor engineers while contributing R&D and roadmaps.

Design, implement, and deploy autonomy capabilities for space platforms including distributed optimization, tasking/scheduling, track fusion, RPO, and motion/behavior planning. Build high-performance, well-tested software modules, collaborate across perception, planning, simulation, hardware, and flight test teams, support deployments and mission log analysis, and contribute R&D and roadmaps to advance autonomy for satellites and missile defense.

Build automated end-to-end tests, frameworks, harnesses, services, and infrastructure for autonomous aircraft software across SIL, HIL, and VIL environments. Automate release testing, orchestration, data collection, analysis, and reporting; debug failures across software, networking, hardware, and simulation; expand system coverage; and integrate testing into CI/CD and release workflows.

Build and own the Linux-based edge platform powering factory, deployable, and air-gapped Crucible environments. Responsibilities include system provisioning, networking, security, updates, recovery, device lifecycle management, hardware and peripheral integrations, disconnected operation, fleet management, and full-stack debugging across applications, operating systems, networks, and physical equipment. The role also partners on edge-to-cloud architecture, deployment topology, and system security.

Senior systems administrator responsible for installing, configuring, monitoring, and securing Windows and Linux servers, virtualization, backup/disaster recovery, cloud identity (Azure AD), automation with PowerShell/Bash/Python, endpoint management, and Tier 1/2 support. Mentor junior admins, maintain documentation, support audits and compliance, and participate in incident response and maintenance activities.

Leads a 10–15-person software engineering section while serving as a technical performer on connectivity and network systems programs. Responsibilities include staffing, recruiting, training, performance management, compensation and career development, conflict resolution, engineering process improvement, and coordination with program teams. The manager will spend approximately 80% of their time supporting software engineering programs and must maintain an inclusive workplace while ensuring workforce readiness and engineering execution.

Conducts end-to-end integration testing for a single-molecule protein sequencing platform. Troubleshoots hardware, software, firmware, optics, fluidics, reagents, consumables, and workflow issues through structured root-cause analysis. Develops test plans and protocols, analyzes instrument and sequencing data, supports verification, validation, characterization, and reliability testing, and documents findings. Collaborates with multidisciplinary engineering, R&D, applications, operations, and customer-facing teams to improve system performance, workflow robustness, commercialization readiness, and field support.

Leads the design, development, integration, testing, and qualification of advanced control solutions for high-precision mechatronic systems supporting semiconductor production. Translates product needs into requirements and verification plans, investigates performance issues, manages technical risks, coordinates cross-functional teams and suppliers, and mentors three to five engineers.