Top Python Jobs in San Diego, CA

The Manager, Solution Architect at PwC leads digital integration projects, focusing on cloud migration, AI-native development, and mentoring engineering teams while ensuring quality deliverables and strategic architecture design.

Lead software development and innovation efforts, mentor teams, manage projects and client relationships, and implement software solutions that drive digital transformation.

Design and implement modern frontend features and UI for an AI-native ERP using Next.js, React, and TailwindCSS. Build structured chat interfaces, real-time dashboards and tables, integrate GraphQL and client-side state, support streaming updates and collaborative UX, and partner with design and product to optimize performance, accessibility, and developer velocity.

Design and implement backend services in Python with PostgreSQL, expose GraphQL APIs for AI agents and real-time frontends, optimize DB performance, contribute to CI/CD and Docker deployments, and enable real-time orchestration across human and AI agents.

Build and operate GovCloud production infrastructure and Kubernetes clusters, own GitOps CI/CD, observability, security/compliance (SOC2/CMMC/FedRAMP), contribute backend code (Python/TypeScript), and improve developer experience and resilience.

Join an agile team to design, develop, test, and deploy secure enterprise software. Participate in SAFe ceremonies, apply software engineering principles, build automation scripts, promote code reuse, and support the full lifecycle in secure environments.

Develop high-fidelity simulations and software interfaces to integrate the Ability Hand with robotic arm platforms using NVIDIA Isaac Sim/Lab and the GR00T AI stack. Build digital twins (URDF/MJCF/SDF), optimize contact and grasp physics, support ROS2-based kinematics, and help develop React interfaces. Collaborate on V&V and DHF deliverables aligned with ISO 13485/14971, and document APIs and architectures for reproducible research and production.

Provide technical support and troubleshooting for customers using the company's bionic products and public API. Develop and maintain ROS and non-ROS example programs and tutorials, collaborate with engineering and sales, conduct demos and training, document support processes, and stay current with industry trends to improve product integration and performance.

The Cloud Systems Engineer will oversee SOLV Energy's Azure and AWS infrastructures, ensuring reliable operations, implementing best practices, and leading project execution while maintaining cloud security and compliance.

Design and develop software for automated laboratory workflows, build data pipelines, implement machine learning models, and integrate various systems to enhance biotherapeutics discovery.

Develop ATE test programs for digital devices, support customers with SmarTest issues, write scripts, and train customers on new solutions.

Own and set technical direction for the Everand backend, building scalable, reliable systems for discoverability, personalization, and core consumption journeys. Drive architecture, platform health (CI/CD, staging, DBs, queues, cost, observability), mentor engineers, lead cross-team planning, modernize legacy systems, and partner with product, design, analytics, web/mobile, and ML to support experimentation and telemetry-driven decisions.

Design, build, and operate backend services and APIs that deliver real-time GNSS/RTK corrections at low latency and high availability. Own ingestion, processing, distribution, observability, and testing of distributed systems while collaborating with cross-functional teams and responding to customer needs. Focus on scalability, reliability, performance, and production readiness for a large device fleet.

Design, develop, and deliver enterprise automation and AI agent solutions using Microsoft Power Platform. Translate business requirements into scalable Power Automate and Power Apps workflows, implement exception handling, monitoring, and resiliency, and maintain production automations. Use Azure DevOps/Git for CI/CD, collaborate with stakeholders, and drive automation governance and process improvements.

Lead design, development, testing, and maintenance of complex software applications in a cross-functional team. Act as technical lead, troubleshoot high-complexity issues, mentor junior engineers, ensure application quality, collaborate with stakeholders, and follow design control and Agile practices. Onsite in San Diego.

The Optical Systems Engineer designs and executes testing for photonic systems, mentors junior engineers, and collaborates on risk assessment and system design.

The Optical Engineer will execute complex engineering tasks, mentor junior engineers, and ensure the accuracy of execution schedule and data quality while engaging with team members and leadership.

The Optical Engineer Level 2 will execute complex engineering tasks, mentor junior engineers, and support optical design and modeling efforts in a startup environment.

As a Principal Optical Engineer, you'll lead optical design projects, ensure data integrity, and drive innovation, while working independently and collaboratively in a startup environment.

The Senior API Engineer is responsible for designing, building, and operating cloud-native REST APIs using Python on AWS, focusing on security, performance, and infrastructure management with Terraform and CI/CD practices.

Lead and execute developmental flight testing of sub-scale and full-scale UAVs. Design and run flight and environmental tests, ensure safety and regulatory compliance, build instrumentation and data-acquisition setups, analyze data (MATLAB/Simulink/Python), coordinate cross-functional teams and test ranges, and document results and corrective actions.

Design, build, integrate, upgrade, and support enterprise-scale Oracle CPQ and Java-based solutions. Partner with stakeholders, implement integrations and APIs, perform production support, execute upgrades/patches, ensure technical governance, and contribute across the software development lifecycle.

Lead a systems infrastructure engineering team using Agile processes. Administer and troubleshoot RHEL/CentOS and Windows servers/workstations, VMware vSphere, automate tasks with PowerShell/Python/Ansible, enforce cybersecurity compliance (SCAP/STIG/Nessus), and maintain configuration management with Teamcenter Enterprise.

Design, simulate, and integrate antennas and RF systems (HF through X-band) for sUAS platforms. Develop link budgets, perform EMI/EMC and cosite analyses, lead antenna integration, execute chamber and flight testing to MIL-STD/DO-160 standards, and produce RF documentation. Support vendor selection, field tests, and RF payload design (SIGINT, EW, comms relay).

Develop, test, and verify RF subsystems for MANET/MIMO radios. Execute RF tests, analyze results, define verification matrices, design test fixtures, troubleshoot EMI/spurious issues, and document findings. Work onsite in San Diego and collaborate with multidisciplinary teams.