Top Senior Python Jobs

20 Days AgoSaved
In-Office
Aurora, CO, USA
92K-171K Annually
Senior level
92K-171K Annually
Senior level
Aerospace • Logistics • Security • Software • Cybersecurity
Develop and maintain software in Python (and Rust) within an Agile team; use Git workflows and Linux; follow SDLC; integrate with databases; requires active Top Secret/SCI clearance and ~10% travel. Opportunity for career growth and relocation assistance.
Top Skills: BitbucketGitGitGitlabLinuxPythonRust
Reposted 20 Days AgoSaved
In-Office
Moonachie, NJ, USA
75K-100K
Senior level
75K-100K
Senior level
Information Technology • Professional Services • Software • 3PL: Third Party Logistics
The Senior Developer is responsible for designing and developing solutions for transforming data files, generating documents, and ensuring optimal process efficiency. Key tasks include managing project requirements, providing technical designs, and maintaining documentation.
Top Skills: Adobe PdfAfpJSONMicrosoft Windows ProductsMs Sql ServerPerlPostscriptPythonShell ScriptingXML
Reposted 20 Days AgoSaved
Remote
USA
Senior level
Senior level
Automotive
The Senior Software Engineer will build a large-scale data ingestion and classification system using web scraping, data processing, and search technologies, overseeing data extraction from various sources and developing search capabilities.
Top Skills: AirflowAWSElasticsearchKubernetesOcrOpensearchPythonScrapySpark
21 Days AgoSaved
Remote
United States
141K-208K Annually
Senior level
141K-208K Annually
Senior level
Database • Analytics
Own and evolve ClickHouse's Python connector and SDKs; build and maintain integrations with orchestration and transformation tools; design AI/LLM integration patterns (RAG, embeddings, feature stores); engage with open-source community; collaborate with Product and Cloud teams to prioritize and ship production-grade data integrations.
Top Skills: Apache AirflowApache FlinkSparkAsyncClickhouseDagsterDbtFivetranKafka ConnectLangchainLlamaindexMultiprocessingN8NNumpyPandasPrefectPydanticPythonSQLSqlmeshThreading
21 Days AgoSaved
In-Office
San Francisco, CA, USA
140K-320K Annually
Senior level
140K-320K Annually
Senior level
Artificial Intelligence • Software • Automation
Build and maintain React + TypeScript web applications and interfaces for AI agent control planes. Partner with designers to harden designer-written code, extend Python backend services and APIs, work in a Kubernetes-native distributed system, and explore agent-native interactive workflows across web and CLI.
Top Skills: KubernetesPythonReactTypescript
Reposted 21 Days AgoSaved
Remote
United States
Senior level
Senior level
Travel
As a Staff Software Engineer, you’ll lead the design and reliability of Duetto's data lakehouse, evolving data systems using Python and AWS, ensuring data quality, and implementing AI-driven solutions.
Top Skills: AirflowAWSDatadogDockerGithub ActionsGlueIcebergPysparkPythonSagemakerSentrySumo LogicTerraform
Reposted 22 Days AgoSaved
In-Office
Conshohocken, PA, USA
Senior level
Senior level
Cloud • Mobile • Software • Design
The Senior Software Engineer will design, develop, and implement software solutions for law enforcement, leading projects and mentoring junior engineers in a collaborative Agile Scrum environment.
Top Skills: Python
23 Days AgoSaved
In-Office
House, NM, USA
Senior level
Senior level
Kids + Family • Retail • Robotics
Provide technical leadership to build, maintain, and optimize core software components/platforms (engine-like) for tech-enabled play using motion, sound, and color detection. Collaborate with firmware and system architects, mentor the team, improve performance on constrained hardware, deliver new experiences, and enhance processes and workflows.
Top Skills: CC++Domain Specific Languages (Dsl)Python
Reposted 23 Days AgoSaved
In-Office
2 Locations
115K-195K Annually
Senior level
115K-195K Annually
Senior level
Information Technology • Software • Database
Maintain and improve the LangChain Python package, enhance documentation, assist users, and build example applications.
Top Skills: Python
Reposted 23 Days AgoSaved
Remote
United States
139K-203K Annually
Senior level
139K-203K Annually
Senior level
Artificial Intelligence • Information Technology • Machine Learning • Marketing Tech • Software • Biotech • Design
Develop and maintain backend solutions, ensuring performance, security, and regulatory compliance, while collaborating in cross-functional teams.
Top Skills: AWSFastapiPython
Reposted 23 Days AgoSaved
Hybrid
Minneapolis, MN, USA
115K-145K Annually
Senior level
115K-145K Annually
Senior level
Consulting • Design
Design and build enterprise web applications using Python backends and React front ends. Develop and consume APIs and microservices, apply cloud and DevOps practices (CI/CD, containers), collaborate with customers and cross-functional teams, and continuously learn and improve using AI-assisted development tools.
Top Skills: AWSAzureChatgptCi/CdClaudeDevOpsGCPGithub CopilotMicroservicesPythonReactRestful Apis
Reposted 23 Days AgoSaved
In-Office
Bethesda, MD, USA
5-5 Annually
Senior level
5-5 Annually
Senior level
Information Technology • Machine Learning • Consulting
Develop and maintain bioinformatics software systems, collaborate with scientists, and implement efficient algorithms for data processing.
Top Skills: BashC++Ci/CdCloud TechnologiesCshDockerGitJavaScriptLinuxMongoDBMs Sql ServerNoSQLPerlPython
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Reposted 23 Days AgoSaved
In-Office
New York, NY, USA
Senior level
Senior level
Information Technology • Software
The role requires a senior developer with expertise in Java and C++, and knowledge of Python. Responsibilities include designing and developing multi-tier applications and handling regulatory projects.
Top Skills: C++JavaPython
Reposted 23 Days AgoSaved
In-Office
New York, NY, USA
Senior level
Senior level
Information Technology • Software
The role involves design and development of multi-tier applications using Java and C++, requiring knowledge of Python and derivatives domain.
Top Skills: C++JavaPython
Reposted 23 Days AgoSaved
In-Office
New York, NY, USA
Senior level
Senior level
Information Technology • Software
The role involves backend development using SQL, mentoring junior staff, participating in project delivery, and ensuring robust team processes.
Top Skills: NetezzaObject DatabasesPerlPowershellPythonRubySQLUnix
Reposted 23 Days AgoSaved
In-Office
New York, NY, USA
177K-265K Annually
Senior level
177K-265K Annually
Senior level
Fintech • Financial Services
Lead design and hands-on delivery of scalable, high-performance Python applications for market and regulatory risk. Architect distributed systems, implement CI/CD, secure REST APIs, collaborate with quants and DevOps, and drive Stress Testing and Regulatory Risk projects under tight deadlines.
Top Skills: Agentic Ai ToolsAngularSparkAWSAzureBitbucket PipelinesCassandraClaudeDevinDjangoDockerFastapiFlaskGCPGitGithub ActionsGithub CopilotGitlab CiGoogle GeminiHadoopJenkinsKafkaKubernetesMongoDBOpenai GptOracleOwasp Top 10PostgresPytestPython 3.XPyTorchReactRedisRestful ApisScikit-LearnSQLSQL ServerTensorFlowUnittestUnixVue
Reposted 23 Days AgoSaved
In-Office
Tampa, FL, USA
114K-171K Annually
Senior level
114K-171K Annually
Senior level
Fintech • Financial Services
Lead design and hands-on development of scalable, high-performance Python applications for market and regulatory risk. Architect distributed systems, enforce SDLC and secure coding, build CI/CD pipelines, integrate with cloud and DevOps, collaborate with Risk/Quants/FO, and deliver stress-testing and regulatory risk solutions under tight deadlines.
Top Skills: AngularSparkAWSAzureBitbucket PipelinesCassandraClaudeCopilotDevinDjangoDockerFastapiFlaskGCPGeminiGitGithub ActionsGitlab CiGptHadoopHugging FaceJenkinsKafkaKubernetesLangchainLanggraphLlamaindexMongoDBOraclePostgresPytestPython 3.XPyTorchReactRedisRest ApisScikit-LearnSQL ServerTensorFlowUnittestUnixVector DbsVue
24 Days AgoSaved
In-Office
Annapolis Junction, MD, USA
Senior level
Senior level
Business Intelligence • Consulting
Designs, develops, tests, and maintains complex software systems for large-scale analytics and real-time processing. Analyzes requirements, debugs defects, documents test results, and recommends improvements and reuse of COTS/GOTS.
Top Skills: Apache AirflowSparkKubernetesPythonTrino
Reposted 24 Days AgoSaved
In-Office
Linthicum Heights, MD, USA
170K-260K Annually
Senior level
170K-260K Annually
Senior level
Big Data • Cloud • Security • Software • Analytics
The Senior Python Software Engineer at GliaCell is responsible for developing and supporting critical software solutions for U.S. Government clients, utilizing Python and various technologies in the cybersecurity domain.
Top Skills: AnsibleAWSDockerElasticsearchGitlab Ci/CdGrafanaKubernetesPythonSplunk
Reposted 24 Days AgoSaved
In-Office
Bellevue, WA, USA
Senior level
Senior level
Artificial Intelligence • Machine Learning • Software
Develop large-scale data analytic applications using Python or R. Familiarity with C#, .NET, and SQL is advantageous. Requires strong problem-solving skills.
Top Skills: .NetC#PythonRSQL
Reposted 24 Days AgoSaved
Remote
United States
Senior level
Senior level
Information Technology • Consulting
Design and build applications using Python, manage component design, optimize performance, and collaborate with clients on innovative products.
Top Skills: Ai ToolsCi/CdGitGoKubernetesPythonReact
Reposted 24 Days AgoSaved
In-Office
Rutherford, NJ, USA
121K-182K Annually
Senior level
121K-182K Annually
Senior level
Fintech • Financial Services
Design, build, and maintain scalable data pipelines and AI agent integrations using Python, PySpark, Databricks, Kafka, and microservices. Develop and deploy GenAI agents, data federation layers, and cloud-native CI/CD microservice integrations while ensuring data quality, security, and compliance.
Top Skills: AngularAWSAzureCi/CdClouderaDatabricksDevin.AiDockerFast ApiGCPGithub CopilotGoogle AdkGoogle Flash LlmsJSONKafkaKubernetesMcpMicroservicesOpenshiftPysparkPythonReact JsScalaSpring BootSQLStarburstYaml
Reposted 24 Days AgoSaved
In-Office
Rutherford, NJ, USA
121K-182K Annually
Senior level
121K-182K Annually
Senior level
Fintech • Financial Services
Design, build, and maintain scalable, enterprise-grade data pipelines, microservices, and AI agents using Python, PySpark, Databricks, Kafka, and cloud-native infrastructure. Develop and deploy agentic GEN AI solutions (Google ADK, LLMs), integrate models via MCP, implement data federation and Data Mesh patterns (Starburst), automate CI/CD for containerized services (OpenShift/Kubernetes), ensure data quality/security, and support risk/compliance in retail and wealth risk engineering.
Top Skills: AngularAWSAzureCi/CdClouderaDatabricksDevin.AiDockerFastapiGCPGithub CopilotGoogle AdkGoogle Flash 2.5JSONKafkaKubernetesMcpMicroservicesOpenshiftPysparkPythonReactScalaSpring BootSQLStarburstYaml
Reposted 25 Days AgoSaved
In-Office
Palo Alto, CA, USA
Senior level
Senior level
Artificial Intelligence • Information Technology • Cybersecurity • Defense
Lead the design, development, and deployment of scalable applications for an AI platform, while mentoring junior developers and optimizing system performance.
Top Skills: Api DevelopmentAzureAzure Cosmos DbDatabase DesignGitLinuxMongoDBPython
Reposted 25 Days AgoSaved
In-Office
23 Locations
120K-228K Annually
Senior level
120K-228K Annually
Senior level
Artificial Intelligence • Consumer Web • Digital Media • Software
Design, implement, and scale event-driven, distributed backend systems in Python on AWS to process and enrich large-scale document and media datasets. Lead technical projects, mentor engineers, integrate ML/LLM components, optimize performance, maintain observability, and collaborate with Data Science, ML Engineering, and Product to deliver reliable high-throughput content processing services.
Top Skills: AirflowAWSCloudwatchDatabricksDatadogEcsElasticacheLambdaLlmMachine LearningPythonScalaSnsSparkSqsTerraform
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