Top Senior IT Jobs in Buffalo, NY

Manage IT vendor and procurement operations including negotiating SaaS, hardware, and services contracts; drive renewals; onboard new vendors ensuring compliance; partner with Legal, Finance, and InfoSec; maintain procurement documentation; support technology asset procurement and improve procurement policies and processes.

The Senior IT Infrastructure Engineer will enhance automation and integration efforts while managing cloud services, CI/CD pipelines, and Kubernetes operations.

Lead and execute remote technical implementations for dental practices from signing through go-live. Configure PMS integrations, set up remote access and network configurations, manage AWS-hosted Windows VMs/ETL, handle support volume, liaise with MSPs, and improve onboarding processes and automation while partnering with cross-functional teams.

Lead end-to-end sales pursuits for IT infrastructure managed services. Build and execute strategic sales plans, penetrate target markets, shape messaging, drive RFP responses and negotiations, and ensure smooth sales-to-delivery transitions while mentoring teams and promoting collaboration.

Lead and coordinate IT and security audits across cloud infrastructure, application security, IAM, vendor risk, and blockchain products; shape audit roadmap; produce executive- and Board-level reports; drive remediation and validate corrective actions; partner with technology leaders and mentor audit staff.

Lead end-to-end IT and security audits across cloud infrastructure, application security, IAM, vendor risk, and blockchain products. Plan and execute fieldwork, produce evidence-based reports for senior leaders and the Audit Committee, mentor junior auditors, validate remediation, and partner with Engineering and Security to improve controls while maintaining audit independence.

Provide Tier 2 technical support and own escalations across devices, apps, and cloud platforms. Administer enterprise SaaS (Google Workspace, Atlassian, Okta, Jamf, Slack), perform root cause analysis, build SOPs/KB content, partner with cross-functional teams, and use automation and generative AI responsibly to reduce tickets and improve service.

The Senior Solutions Architect II leads the design and implementation of large-scale solutions, drives innovation, and mentors team members. They also collaborate on pre-sales with Sales teams and serve as technical escalation points for complex issues.

Lead architecture and delivery of IT automations and integrations across platforms (n8n, Airflow, Temporal, Jira). Act as technical DRI for complex automation projects, partner with Security and IAM, build reusable frameworks and documentation, establish engineering standards and code review practices, and mentor peers.

Own IT-specific Sarbanes-Oxley (SOX) compliance for ITGCs and ITACs. Assess SOX readiness for systems and process changes, maintain control documentation, coordinate walkthroughs and remediation, liaise with internal/external auditors, review SOC reports, oversee testing programs, and identify automation and AI opportunities to strengthen controls and reporting.

Support risk assessment, audit planning, and oversight of audit management and staff. Provide advisory services and ensure compliance with standards.

Lead and maintain school IT systems, networks, databases, and help desk operations. Develop and implement technology plans, ensure uptime/security, supervise IT staff, provide on-site support, and advise administration on technology strategy and procurement.

The Lead Technical Support Engineer resolves complex technical issues, provides mentorship, collaborates with teams, and improves support systems.

The role involves developing, testing, and maintaining computer programs, supporting complex analyses, managing development efforts, and ensuring alignment with organizational methodologies.

The Test Manager designs and executes comprehensive testing processes, manages testing events, oversees engineering activities, ensures effective schedule and resource allocation, and maintains quality assurance for large-scale systems integration.

Lead IT SOX and internal control testing for ICFR engagements: plan and test ITGCs and application controls, perform walkthroughs, assess control design and operating effectiveness, document findings, support SOX readiness, and advise clients on control remediation and improvement opportunities.

Lead and manage the endpoint management team delivering secure, standardized endpoint services. Oversee full endpoint lifecycle (procurement, Autopilot provisioning, patching, security, refresh/retirement), act as senior technical escalation point, drive automation with PowerShell and Microsoft Graph, manage projects and M&A integrations, maintain documentation and standards, collaborate cross-functionally, and develop team skills through coaching and certification roadmaps.

Lead SOX IT/internal controls engagements: plan and test ITGCs and application controls, perform walkthroughs, document controls and risks, support SOX readiness and integrated audits, provide recommendations, and use technology-based tools to assess control design and operating effectiveness.

The Internal Audit Manager will lead audit activities over the Commercial domain, manage risks, coach team members, ensure compliance, and maintain stakeholder relationships to enhance audit processes and outcomes.

Lead and execute IT infrastructure and operations audits from planning through reporting, ensuring compliance with auditing standards. Perform risk assessments, continuous monitoring, remediation validation, and communicate findings to management. Coach and supervise auditors, incorporate data analytics and automation, and maintain subject-matter expertise in IT controls and regulatory requirements.

Perform financial analyses for IT, develop Total Cost of Ownership and forecasting models, and recommend financial strategies. Support IT operations/governance, integrate financial checkpoints into governance, and apply Agile delivery principles to align services and outcomes.

Design, deploy, and optimize secure, scalable AWS environments. Lead migrations, build Infrastructure as Code (Terraform/CloudFormation/Ansible), apply FedRAMP/NIST security controls, manage cost/performance, operate containerized apps (ECS/EKS/Docker), integrate CI/CD pipelines, and lead stakeholder technical discussions to align cloud solutions with mission goals.

Lead and continuously improve the global IT Compliance function for a CRO, ensuring IT governance, ISMS and ISO 27001 certification support, GxP computerised system compliance, audit readiness and vendor/third-party compliance oversight. Provide regulatory guidance, manage audit responses, run risk assessments, maintain compliance documentation, and drive remediation and continual improvement across IT and business stakeholders.

Manage operations and maintenance of Consumer Health S/4HANA ecosystems, including request and incident lifecycle, event management, application security, capacity and production transition, vendor escalations, and continuous service improvement to ensure rapid recovery and reliable service delivery.

Serve as Product Owner for Oracle/Cerner clinical solutions, partnering with stakeholders to define workflows, write user stories, manage backlogs, configure systems, support enterprise deployment and adoption, and provide SME through the product lifecycle. Requires risk mitigation, cross-team collaboration, and occasional travel.