Top Senior IT Jobs in Buffalo, NY

Lead enterprise IT procurement strategy, governance, and operations across hardware, software, cloud, and services. Own vendor relationships, commercial negotiations, licensing and asset lifecycle, M&A procurement integration, and procurement process/tooling. Mentor and scale the procurement team, partner with Finance, Legal, and Security, and deliver executive reporting and cost-optimization initiatives.

Act as the technical lead for field sales, manage evaluations, deliver on-site and remote demos, prepare SOWs/RFIs/RFPs, respond to security questionnaires, train sales teams, and support sales across U.S. and Canada while maintaining client relationships and achieving technical sales targets.

Sell radiology IT solutions by building strategic account plans, managing long technical sales cycles, maintaining a 3-5× quota pipeline, forecasting in Salesforce, partnering with marketing/inside sales, and representing the company at industry conferences.

Lead IT SOX controls testing for ITGCs (access, change, operations) across blockchain-native and enterprise systems. Build testing programs, validate remediation, perform root-cause analysis, report to Audit Committee, and collaborate with Engineering, Security, and external auditors to ensure SOX compliance and scalable audit processes.

Lead strategy and execution for enterprise infrastructure, cloud platforms, and systems reliability. Build and scale a high-performing IT operations team, drive automation and observability, manage incident and change processes, partner cross-functionally on security and architecture, and lead large-scale infrastructure transformation to ensure resilient, scalable services.

First IT hire responsible for end-to-end IT: systems administration (Rippling, Google Workspace, SSO), device lifecycle, help desk, vendor and license management, security operations (endpoint protection, phishing simulations, awareness training), and establishing HIPAA compliance and documentation.

Lead information security governance, risk, and compliance programs. Manage cross-functional teams, SOC 2 Type II audits, regulatory engagements, enterprise data security and governance, incident communications, information security questionnaires, KPI/KRI reporting, and mentor junior staff to ensure regulatory and standards alignment.

Lead Manhattan Active WM solution design and multi-site rollout, migrate legacy WMS/TMS/WES/WCS, define processes and standards, validate warehouse hardware and automation, manage integrations, testing, cutover, go-live stabilization, documentation, and mentor internal teams.

Support and enforce NIST/CMMC-aligned security controls; monitor SIEM/EDR and perform incident triage and response; manage Windows/AD environments; conduct vulnerability scanning and remediation; protect and classify FCI/CUI; support audits and control validation; maintain compliance documentation; collaborate with IT and business teams and communicate security risks to technical and non-technical stakeholders.

The Director of IT Operations leads the IT infrastructure, ensuring reliability, security, scalability, and efficiency while supporting business growth and managing the IT Operations team.

The Manager of IT Engineering leads IT operations including identity management, SaaS, endpoint management, and internal tooling. This role ensures service quality and scalability for a remote workforce.

Lead IT procurement and contracting for Digital Services: run RFx/RFPs, draft and negotiate contracts, manage renewals, oversee software licensing and vendor relationships, maintain procurement records, resolve disputes, and mentor junior staff.

Lead global strategic sourcing for IT & automation categories ($450M+ spend). Develop category strategies, drive multi-million dollar savings, lead supplier relationship and risk management, conduct tenders and contract negotiations (> $500K), mentor sourcing managers, align senior stakeholders, implement supplier performance KPIs and innovation, and support cross-functional procurement initiatives. Expect ~20% travel.

The IT Communications Officer manages all IT networks and systems on board luxury cruise ships, providing technical support, user management, and ensuring communication infrastructure is operational.

The IT Project Manager will oversee project planning, implementation, and client interactions while ensuring compliance with federal and state regulations in the public sector.

The IT Project Manager will lead public sector ERP migration projects, ensuring high-quality deliverables and strategic alignment while collaborating with various stakeholders.

Build end-to-end automation and AI agents across identity, endpoint, SaaS, and ITSM systems. Automate onboarding/offboarding, ticket triage, self-service flows, and integrations. Operate and govern Vertex AI agents, establish KPIs, mentor sysadmins, and maintain reliable, auditable automations with security and compliance controls.

The Senior IT Project Manager oversees the delivery of technology and business transformation projects, supports PMO standards, manages project risks, and mentors junior managers.

The IT Systems Engineer will manage IT operations, support M&A integrations, and optimize Microsoft cloud systems, ensuring reliability and security.

The Senior IT Risk and Compliance Analyst manages vendor risk, ensures compliance with regulations, documents controls, and supports risk mitigation efforts across IT teams.

The IT Manager, Product Owner - Finance drives financial process transformations, prioritizes product backlogs, and manages stakeholder relationships to ensure high-quality delivery of financial systems solutions.

Serve as the primary IT–business liaison, owning executive relationships, technology strategy, vendor management, and prioritization of IT/AI initiatives. Drive modernization, cost/benefit analyses, budgeting, continuous improvement, and successful deployment of technology solutions across business units.

The IT Operations Manager will oversee the internal technology ecosystem, ensuring reliability, security, and optimization of IT operations, while leading a team and collaborating with business leaders.

The Senior Procurement Manager will oversee IT sourcing and software procurement, manage renewals, drive savings, and mentor team members in procurement practices.

The Sr. Manager of Indirect Procurement will oversee procurement strategies to enhance cost efficiencies, ensuring the best products and services for veterinary practices.