Top Senior Data Science Jobs in Buffalo, NY

Lead design and delivery of scalable ML systems across the full lifecycle for recommendations, demand forecasting, targeting, and personalization. Collaborate with engineers, product, and stakeholders to set architecture, metrics, and production best practices; mentor data scientists; lead experimentation and deploy/monitor models using cloud and MLOps tooling.

As a Staff Data Scientist at SentiLink, you will develop fraud detection models, conduct analyses, collaborate across teams, and drive the development of financial risk products.

Lead product analytics to inform strategy and optimize user experience: translate business questions into analysis, build reliable analytics infrastructure, run A/B tests and ML/statistical analyses, track funnels and cohorts, support 0-to-1 product launches, and communicate actionable insights to cross-functional teams.

Lead development and deployment of bioprocess digital twin models for CHO cell culture and upstream workflows. Build hybrid mechanistic/ML models, enable virtual experiments and forecasting, define data and validation requirements, and support real-time monitoring to detect deviations and recommend corrective actions.

Lead and deliver end-to-end data science projects: design, build, deploy, and monitor ML/statistical models for credit risk, pricing, collections, and fraud. Partner with cross-functional teams to integrate models into production, set model development standards, mentor engineers, and maintain reliable ML pipelines and monitoring systems.

As a Senior Data Scientist, you will lead high-complexity projects, develop ML and NLP solutions, and collaborate across teams to drive business impact through statistical modeling and data analysis.

Support enterprise cardiovascular quality improvement and clinical research by analyzing clinical datasets, developing dashboards and reports, performing cohort development and statistical analyses, ensuring regulatory and data governance compliance, and communicating findings to clinical and operational stakeholders to inform quality and research initiatives.

Own end-to-end modeling for vendor matching, order routing, and supply-chain optimization. Build predictive, causal, RL and OR solutions; design autonomous decision logic; quantify counterfactual impact; ship production models with data engineering; mentor senior data scientists; write technical design docs; partner on quarterly priorities and expand into revenue cycle and finance domains.

Design and deploy predictive forecasting and analytics to support Revenue operations. Build models for forecasting, churn, expansion, and pipeline analytics; create scalable dashboards; partner with Revenue Operations, Finance, and Data Engineering to improve data quality, KPI governance, and executive reporting to drive data-driven decisions and AI readiness.

Lead company-level measurement and causal strategy, define MAU×ARPU metrics and semantic mart, set scientific standards for experimentation and analysis, own strategic models (MMM, elasticity, forecasting), partner with engineering to productionize analytics, and raise org-wide scientific maturity through governance, templates, and upskilling.

Lead end-to-end supply chain planning science: own forecasting tournaments, inventory placement optimization, vendor performance systems, and raw-material signals. Define methodology, production models, and iteration loops; drive AI-native workflows (LLM-aided EDA, agentic feature engineering), partner with planning operators and engineering, and mentor junior scientists to raise methodological standards and deliver measurable business impact.

Lead end-to-end supply chain planning and forecasting modeling: demand forecasting across geographies, forecasting tournaments, inventory placement optimization, vendor performance modeling, and raw-material signal generation. Collaborate with leadership and engineering to productionize models and apply AI-native techniques (LLM-aided EDA, agentic feature engineering, AI-augmented experimentation).

Lead design, build, and production deployment of generative AI products (LLM apps, agents, copilots, RAG/search). Rapidly prototype features, build APIs/services and retrieval pipelines, optimize performance, ensure responsible AI, and mentor team members while setting AI technical direction across the organization.

Lead quantitative analysis and modeling of large real-world health datasets to estimate population-level disease prevalence and incidence. Design and implement statistical and machine learning models, maintain data pipelines and dashboards, ensure data quality and reproducibility, collaborate with clinicians and public health experts, prepare scientific reports, and support team onboarding and training.

Build and scale production-ready generative AI applications: design multi-agent workflows, implement advanced RAG with vector DBs, integrate/swap LLMs, fine-tune models, and deploy scalable FastAPI/Docker services with monitoring and optimization for latency, cost, and reliability.

Design, build, and deploy production-ready generative AI applications: architect multi-agent workflows, implement advanced RAG with vector DBs, integrate/swap LLMs, fine-tune models, and deliver scalable FastAPI-based services with monitoring, CI/CD, and containerized deployment.

Build and scale production Generative AI applications: design multi-agent systems and LangGraph workflows, implement advanced RAG with vector DBs, integrate and fine-tune LLMs, deploy FastAPI async services in Docker, and optimize GenAI performance, cost, and monitoring.

Design, build, and deploy machine learning and generative AI models (including LLMs and text-to-image). Analyze large datasets, run A/B and statistical tests, collaborate with data engineering and engineering teams, and create dashboards/visualizations to communicate insights. Optimize data pipelines and model performance to support data-driven decisions.

Senior individual contributor who drives product analytics, experimentation, and applied modeling. Owns growth and performance analyses, designs experiments with robust statistical evaluation, builds repeatable reporting, and partners with Product, Engineering, Operations, Clinical, and Finance to translate data into actionable product and operational decisions.

Designs, analyzes, and interprets clinical trial, RWE, and observational data for a medical device. Develops statistical plans, predictive models, and ensures data quality, regulatory compliance, and traceability. Collaborates with clinical, regulatory, and data teams, supports submissions and publications, mentors interns, and represents the company externally.

Seeking a skilled Data Scientist/Machine Learning Engineer to develop machine learning models, design AI systems, and collaborate in data analytics. Responsibilities include productionizing models, data engineering, and cross-functional collaboration.

Design, implement, and maintain marketing inference models (e.g., MMM and attribution). Analyze large datasets and A/B/uplift experiments with rigorous statistics, build predictive and causal models, partner with marketing to generate testable ideas, and communicate insights to drive marketing decisions.

As a Senior Marketing Data Scientist, you will conduct quantitative analyses, manage marketing tests, and provide actionable insights to enhance marketing performance and investment effectiveness.

As a Staff Data Scientist, you will analyze large-scale broadband data, develop and validate ML models, and integrate solutions into Calix Cloud, collaborating with teams for enhanced network intelligence and subscriber experience.

Senior individual contributor owning complex end-to-end ML problems for supply chain and consumer applications. Build and deploy predictive models (demand forecasting, delivery ETA, recommendations), embed with engineering teams, define MLOps standards, and advise leadership on data science strategy and investments.