Top Senior IT Jobs in Buffalo, NY

Own vendor procurement, contracts, provisioning, and IT strategy for employee hardware/software. Manage SSO/onboarding/offboarding, device management, SOC2 audit evidence, vendor negotiations, cost audits, and automation of provisioning processes.

Lead IT SOX controls testing for ITGCs (access, change, operations) across blockchain-native and enterprise systems. Build testing programs, validate remediation, perform root-cause analysis, report to Audit Committee, and collaborate with Engineering, Security, and external auditors to ensure SOX compliance and scalable audit processes.

Act as the technical lead for field sales, manage evaluations, deliver on-site and remote demos, prepare SOWs/RFIs/RFPs, respond to security questionnaires, train sales teams, and support sales across U.S. and Canada while maintaining client relationships and achieving technical sales targets.

Sell radiology IT solutions by building strategic account plans, managing long technical sales cycles, maintaining a 3-5× quota pipeline, forecasting in Salesforce, partnering with marketing/inside sales, and representing the company at industry conferences.

Provide senior procurement support for cloud products and tools: manage purchase requisitions, vendor relationships, license administration, asset tracking, renewals, funding/ROMs, and contract deliverables using Jira/Confluence and other procurement systems. Ensure timely, compliant procurements, track funding against contracts, coordinate training, and drive process improvements to optimize spend and customer experience.

Lead multiple AI engineering and innovation squads to design, build, and scale AI-powered products on Google Cloud. Translate AI strategy into roadmaps, provide technical leadership across architecture, DevSecOps, CI/CD, telemetry, and APM, manage budgets/vendors, hire and develop teams, and ensure production reliability, security, and measurable business value.

Lead a team to design, build, and operate scalable, secure platform and MLOps capabilities on GCP and hybrid cloud. Drive DevSecOps, CI/CD, telemetry, and platform modernization to accelerate AI/ML and software delivery while managing delivery, budgets, vendors, and stakeholder alignment.

Lead cloud financial governance for a federal enterprise: manage chargeback/showback, cost optimization, forecasting, anomaly detection, procurement alignment, and executive dashboards to ensure VA fiscal policy compliance and large-scale cloud spend oversight.

Lead global IT sourcing strategy and a multi-year technology modernization agenda. Manage $450M spend, strategic supplier relationships, governance, risk, and value delivery. Oversee category management (cloud, software, infrastructure, cyber), negotiations with hyperscalers and SaaS vendors, stakeholder engagement, and build a high-performing sourcing organization.

The IT Manager, Product Owner - Finance drives financial process transformations, prioritizes product backlogs, and manages stakeholder relationships to ensure high-quality delivery of financial systems solutions.

The IT Project Manager will oversee project planning, implementation, and client interactions while ensuring compliance with federal and state regulations in the public sector.

The IT Project Manager will lead public sector ERP migration projects, ensuring high-quality deliverables and strategic alignment while collaborating with various stakeholders.

Lead enterprise analytics architecture and strategy across Epic Cogito, BI tools, and cloud platforms. Design scalable, secure solutions, enforce RBAC and DevOps/CI-CD practices, mentor federated teams, guide tool selection, and ensure alignment with business priorities. Provide architectural oversight, stakeholder consultation, and adoption planning for analytics initiatives in a large healthcare system.

The Project & IT Budget Analyst manages project coordination and IT budget oversight, supporting strategic initiatives and ensuring financial accuracy.

Build and maintain internal platforms, automations, and integrations to scale IT operations. Own identity, access, lifecycle automation, endpoint trust, SaaS provisioning, and operational reporting. Develop scripts and services (Python, Bash), partner with Security and Engineering for secure AI, Zero Trust, HIPAA and SOC 2 compliance, and apply DevOps/SRE/ITIL practices for monitoring and incident response.

Senior Full Stack Engineer to design, develop, and improve NIH NHLBI BioData Catalyst applications. Work across the software lifecycle, contribute frontend and backend code, improve existing codebases, support CI/CD, Azure databases, and collaborate in Agile teams to deliver maintainable, testable scientific data applications.

The Senior IT Project Manager oversees the delivery of technology and business transformation projects, supports PMO standards, manages project risks, and mentors junior managers.

The Senior IT Risk and Compliance Analyst manages vendor risk, ensures compliance with regulations, documents controls, and supports risk mitigation efforts across IT teams.

Lead IT Product Management and Software Asset Management for internal enterprise systems (ERP/CRM/HRIS). Set product strategy, prioritize demand, govern SaaS lifecycle, lead OCM and adoption, oversee delivery (QA/UAT/releases/hypercare), build metrics, and manage and develop a cross-functional BT product and asset team.

Lead global IT operations for a HIPAA-regulated healthtech company, managing a small support team and hands-on ticketing. Build and maintain systems for compliance and visibility, optimize vendor costs, implement security/onboarding processes, drive process improvements with KPIs and automation, and serve as primary IT liaison to leadership and partners.

Lead design, implementation, and operation of a scalable, secure cloud data platform (data lake/warehouse/lakehouse). Build data pipelines, migrations, archival, IaC provisioning, CDC-enabled ingestion, governance, multi-tenant security, DR/HA, and performance optimization to support reporting, analytics, and AI/ML for a federal judiciary modernization program.

Lead the Case Management Modernization data governance and modernization team to deliver integrated data governance, cloud-based data platform, reporting, analytics, and AI/ML capabilities. Oversee contract execution, define technical strategy and architecture, ensure security and compliance, manage Agile delivery (IMS, RAID, sprints), supervise personnel, engage stakeholders, report performance, and drive risk identification and mitigation to meet program objectives.

Lead end-to-end IT sourcing for hardware, software, SaaS, and security services. Develop sourcing strategies, run RFx and negotiations, draft and manage contracts, perform market and TCO analysis, mitigate risks, manage supplier performance, and align cross-functional stakeholders to optimize cost, performance, and vendor portfolios.

Provide frontline and advanced application support for radiology imaging workflows: incident triage, user provisioning, configuration changes, DICOM troubleshooting, monitoring interfaces, coordinating with networks/storage/vendors, maintaining SOPs and knowledge base, delivering end‑user training and on‑call doctor support to meet SLAs.

Manage and grow a remote helpdesk team while providing hands-on tier 2/3 support. Own ticket triage, SLAs/KPIs, onboarding/offboarding, M365/Google Workspace and Azure AD administration, endpoint management via Intune/MDM, vendor and asset lifecycle, security policy enforcement, documentation, and process improvement.