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Top Senior IT Jobs in Buffalo, NY

Reposted YesterdaySaved
Remote
Buffalo, NY
100K-152K Annually
Senior level
100K-152K Annually
Senior level
Healthtech
The role involves strategic sourcing for indirect goods and services, overseeing supplier relationships, driving cost savings, and developing procurement strategies while collaborating with cross-functional teams.
Top Skills: Sourcing Technology Solutions
Reposted 2 Days AgoSaved
Remote
Buffalo, NY
Senior level
Senior level
Industrial
As a Lead IT Systems Analyst at AssetWatch, you'll provide technical leadership, manage endpoint and systems architecture, ensure security compliance, implement automation, and mentor junior staff in a remote-first environment.
Top Skills: Azure AdBashIntuneJamf ProJira Service ManagementmacOSMicrosoft 365NinjaonePowershellPythonServicenowWindows
3 Days AgoSaved
Remote
Buffalo, NY
Senior level
Senior level
Information Technology • Consulting
Lead the transformation of identity management by modernizing architecture, automating processes, and integrating identity workflows within enterprise environments.
Top Skills: Aws IamAzure AdGcp IamGitOktaPaylocityPowershellPythonTerraformWorkday
Reposted 3 Days AgoSaved
Remote
Buffalo, NY
140K-170K Annually
Senior level
140K-170K Annually
Senior level
Co-Working Space or Incubator
The IT Systems Engineer manages and maintains the corporate unclassified network, Google Workspace, and provides end-user support, ensuring security compliance and efficient operations.
Top Skills: AWSCiscoGoogle WorkspaceMicrosoft EntraVMwareWindows
Reposted 3 Days AgoSaved
Remote
Buffalo, NY
Senior level
Senior level
Artificial Intelligence • Fintech • Software • Financial Services
The IT Manager will build the IT function at Oscilar, manage corporate IT processes, resolve technical issues, and ensure compliance with frameworks.
Top Skills: Endpoint ManagementIdentity And Access ManagementMdmSaas ManagementSso
Reposted 3 Days AgoSaved
Remote
Buffalo, NY
6-6 Annually
Senior level
6-6 Annually
Senior level
Information Technology
Manage and lead a team of IT analysts, ensuring service level agreements and customer satisfaction while fostering a culture of continuous improvement and collaboration.
Top Skills: HexServicenowTableauZendesk
Reposted 4 Days AgoSaved
Remote
Buffalo, NY
88K-135K Annually
Senior level
88K-135K Annually
Senior level
Consulting
The IT Project Manager will lead public sector ERP migration projects, ensuring high-quality deliverables and strategic alignment while collaborating with various stakeholders.
Top Skills: AgileBusiness IntelligenceCloud-Based ErpData AnalysisData MigrationIv&VPeoplesoftSap S/4Hana RiseSoftware DevelopmentWaterfall
14 Days AgoSaved
In-Office
Buffalo, NY
55K-80K Annually
Senior level
55K-80K Annually
Senior level
Cloud • Information Technology • Consulting
The IT Systems Administrator & Support provides technical support, manages IT infrastructure including servers and networks, and ensures compliance with patch management policies.
Top Skills: AcronisActive DirectoryDhcpDnsGroup PolicyKaseyamacOSMicrosoft 365PowershellSonicwallVeeamVMwareWindows 10Windows Server
Reposted 15 Days AgoSaved
In-Office
Buffalo, NY
90K-149K Annually
Senior level
90K-149K Annually
Senior level
Fintech
Lead audits over IT operations, oversee audit activities, establish relationships with stakeholders, communicate findings, and manage audit processes. Develop others and ensure compliance with internal control standards.
Top Skills: Api ManagementCloud ComputingData Backup SolutionsDatabase Management PlatformsDevops ToolsEmail Management SystemsFirewallsItil StandardsMainframe SystemsMiddleware TechnologiesNetwork InfrastructureServer Operating SystemsServer Virtualization SystemsStorage InfrastructureVpn
6 Days AgoSaved
Remote
Buffalo, NY
105K-179K Annually
Senior level
105K-179K Annually
Senior level
Healthtech • Pharmaceutical
The Senior IT Product Manager will oversee product strategy, roadmap, and execution for IT solutions, ensuring alignment with business value and stakeholder needs. Responsibilities include project management, vendor relations, financial planning, and cross-functional collaboration.
Top Skills: Agile Methodologies
Reposted 6 Days AgoSaved
Remote
Buffalo, NY
Senior level
Senior level
Healthtech
The Senior IT Program Manager leads and manages IT programs/projects, ensuring they meet business needs and are delivered on time and within budget while collaborating with stakeholders.
Top Skills: ConfluenceJIRAMicrosoft ProjectMS OfficeSnow Spm
Reposted 6 Days AgoSaved
Remote
Buffalo, NY
Senior level
Senior level
Healthtech
The Senior IT Project Manager oversees the delivery of technology and business transformation projects, supports PMO standards, manages project risks, and mentors junior managers.
Top Skills: JIRAMs ProjectServicenow PpmSmartsheet
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Reposted 6 Days AgoSaved
Remote
Buffalo, NY
Senior level
Senior level
Healthtech
The Vice President of IT Infrastructure & Operations leads IT strategy, manages infrastructure, ensures service delivery, and drives ITSM transformation in a healthcare setting.
Top Skills: AWSAzureBmcCmdbCybersecurity FrameworksGCPItilM365Sd-WanServicenowVpn
Reposted 6 Days AgoSaved
Remote
Buffalo, NY
Senior level
Senior level
Healthtech
The Senior IT Program Manager leads program execution from inception to launch, aligning business needs with IT strategies, managing budgets, and building stakeholder relationships.
Top Skills: ConfluenceJIRAMicrosoft ProjectMS OfficeSnow Spm
Reposted 6 Days AgoSaved
Remote
Buffalo, NY
170K-185K Annually
Senior level
170K-185K Annually
Senior level
Marketing Tech • Mobile • Software
Lead internal IT operations, manage infrastructure and systems, enhance security, mentor IT staff, and implement scalable tech solutions.
Top Skills: Cloud-Based SystemsDlpEdrIdpMdmVpn
Reposted 6 Days AgoSaved
Remote
Buffalo, NY
Senior level
Senior level
Healthtech
The Sr Application Support Analyst provides Level 2+ IT application support, troubleshooting issues, recommending solutions, and improving business processes while ensuring user satisfaction.
Top Skills: ServicenowSQL
Reposted 6 Days AgoSaved
In-Office or Remote
Buffalo, NY
Senior level
Senior level
Healthtech • Information Technology
The Senior IT Risk and Compliance Analyst manages vendor risk, ensures compliance with regulations, documents controls, and supports risk mitigation efforts across IT teams.
Top Skills: Audit MethodologiesCobitIso27001Iso27002NistServicenow Irm
Reposted 6 Days AgoSaved
Remote
Buffalo, NY
92K-138K Annually
Senior level
92K-138K Annually
Senior level
Healthtech • Pharmaceutical
Serve as the primary IT–business liaison, owning executive relationships, technology strategy, vendor management, and prioritization of IT/AI initiatives. Drive modernization, cost/benefit analyses, budgeting, continuous improvement, and successful deployment of technology solutions across business units.
Top Skills: AIAutomationLims
7 Days AgoSaved
Remote
Buffalo, NY
130K-156K Annually
Senior level
130K-156K Annually
Senior level
Fintech • Professional Services • Software • Financial Services
The IT Systems Engineer will manage IT operations, support M&A integrations, and optimize Microsoft cloud systems, ensuring reliability and security.
Top Skills: Active DirectoryAzureCloud-Based PlatformsEndpoint ManagerEntra IdIntuneLan/Wan InfrastructureMicrosoft 365Microsoft Defender Xdr
7 Days AgoSaved
Remote
Buffalo, NY
102K-150K Annually
Senior level
102K-150K Annually
Senior level
Artificial Intelligence • Big Data • Machine Learning • Security • Software • Cybersecurity • Big Data Analytics
As a Senior Business Systems Analyst, you'll manage SaaS portfolios, identify AI automation opportunities, gather requirements for engineering, and provide insights into cross-functional initiatives.
Top Skills: AIAPIsJIRAMonday.ComNo-Code PlatformsSaaSWorkflow Tools
7 Days AgoSaved
Remote
Buffalo, NY
132K-160K Annually
Senior level
132K-160K Annually
Senior level
Healthtech
Lead program management for an EHR migration, coordinating cross-functional teams, managing vendor relationships, and ensuring project execution and governance throughout the program lifecycle.
Top Skills: Monday.ComSmartsheet
7 Days AgoSaved
In-Office or Remote
Buffalo, NY
Senior level
Senior level
Retail • Sales
The IT Manager, Product Owner - Finance drives financial process transformations, prioritizes product backlogs, and manages stakeholder relationships to ensure high-quality delivery of financial systems solutions.
Top Skills: CertiniaCpqFinancialforcePower BISalesforceServicemaxSQLZuora
7 Days AgoSaved
Remote
Buffalo, NY
103K-120K Annually
Senior level
103K-120K Annually
Senior level
Information Technology • Software
The IT Portfolio & Demand Management Analyst manages portfolio-level visibility, demand intake, prioritization, capacity analysis, and financial reporting to support executive decision-making and project delivery execution.
Top Skills: Azure DevopsClarityPlanviewServicenow Spm
Reposted 7 Days AgoSaved
Remote
Buffalo, NY
90K-95K Annually
Senior level
90K-95K Annually
Senior level
Information Technology
Lead functional and ETL testing of Pharmacy Rebate and Claims platforms, ensuring data integrity and validating claims processing logic through hands-on testing and advanced SQL querying.
Top Skills: ETLMs DevopsSQL
Reposted 8 Days AgoSaved
In-Office or Remote
Buffalo, NY
141K-305K Annually
Senior level
141K-305K Annually
Senior level
Healthtech • Insurance
The Director of IT Applications Development oversees the strategy and implementation of enterprise applications in healthcare, focusing on integrating Epic with various systems to optimize clinical operations and patient experience.
Top Skills: APIsCloverleafEdi X12EpicFhirHl7AzureMirth ConnectMulesoftRhapsody
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