Top Senior Python Jobs in Buffalo, NY

The Senior Python Engineer will develop and support MongoDB Python drivers, enhance library quality, and collaborate on product features.

Design, develop, and maintain scalable Python applications; collaborate with cross-functional teams to deliver features; ensure performance and quality; identify and fix bugs; maintain code quality and automation; lead and mentor team members using agile practices.

Evaluate AI coding-agent interactions for usefulness, correctness, engineering judgment, reasoning quality, and user trust. Provide rigorous, opinionated feedback distinguishing response quality levels and help define best practices for tools such as OpenAI Codex, Claude Code, and Cursor. This contract role requires strong software engineering expertise, familiarity with AI-assisted development workflows, and the ability to assess code and explanations without deeply reviewing or executing every line.

Design, build, and maintain scalable full-stack web applications using React, Python, Node.js, and C#. Develop cloud-native AWS solutions with event-driven and serverless architectures, manage relational and NoSQL data stores, write automated tests, maintain infrastructure as code, and contribute to CI/CD pipelines. Collaborate with cross-functional engineering teams on architecture, security, performance, and end-to-end feature delivery in an agile environment.

Develop and maintain end-to-end applications using Python, Node.js, C#, and React. Build scalable backend services, frontend features, APIs, cloud-native AWS solutions, automated tests, infrastructure as code, and CI/CD pipelines. Collaborate with cross-functional engineering teams in an agile, remote environment while contributing to architecture and reliable product delivery for US clients.

Design, develop, test, and maintain scalable Python applications, backend services, REST APIs, microservices, and integrations. Work with databases, asynchronous processing, cloud platforms, containers, CI/CD, security, observability, and distributed systems. Troubleshoot production issues, optimize performance, create automated tests, participate in code reviews and architecture decisions, and collaborate with product, DevOps, QA, and engineering teams.

Develop open source SDKs, enterprise APIs, UIs, and backend systems supporting large-scale computer vision datasets. Build scalable, maintainable, performant, and well-tested software for unstructured data and AI workflows. Contribute to enterprise deployments across customer clouds and on-premises environments, while improving tooling, automation, engineering practices, and open source community initiatives in a remote-first team.

Design, develop, and maintain scalable Python applications and cloud-native solutions. Architect microservices, containerized deployments (Docker/Kubernetes), optimize cloud infrastructure, build CI/CD pipelines, integrate messaging systems, ensure security and high code quality, and mentor junior developers. Generative AI/ML experience is a plus.

The Backend Software Engineer will develop and maintain backend systems for data processing related to coffee farming, utilizing Python and PostgreSQL. Responsibilities include feature development, problem-solving, and adapting systems to regulatory changes while ensuring system resilience.

The Senior Full Stack Developer will design, develop, test, and debug software solutions, collaborating with teams and optimizing applications. Responsibilities include user interaction design, back-end functionality, and ensuring software scalability and security.

Lead Software Engineer responsible for designing, developing, testing, and maintaining a distributed processing application using Python and Java. Collaborate with product owners, data coaches, analysts, DBAs, and Agile teams to meet backend/frontend requirements, implement cloud and big-data solutions (Spark/Hadoop), and ensure program standards and reliable delivery.

Develop, test, and maintain a complex distributed processing application using Python and Java. Collaborate with product owners, data coaches, analysts, DBAs, and Agile teams to meet backend/frontend requirements. Work with distributed workloads (Spark/Hadoop), SQL/Snowflake, AWS, shell scripting, and job scheduling/process automation. Support delivery under Agile/SAFe practices and ensure alignment with program standards.

Lead development of Python-based web applications using Django and FastAPI, architect scalable solutions, and establish technical standards while mentoring developers and optimizing infrastructure.

The Python Engineer will write maintainable Python software, lead technical initiatives, collaborate globally, and contribute to community engagement at Canonical.

Develop and enhance features for EnrollWise, contribute to a scalable software architecture, review code, collaborate on design and technical feasibility, and maintain software quality.

Lead the design and development of scalable Python backend services and APIs on AWS, mentor engineers, and manage PostgreSQL databases in a healthcare technology environment.

Build and maintain full-stack wealth management platform features using Python and Angular or React. Design service-oriented architectures and REST/SOAP APIs, work with relational databases and ORMs, contribute to AWS or Azure cloud architecture, and deploy using container technologies. Collaborate in Agile/Scrum ceremonies, participate in code reviews and demos, and work independently with distributed teams.

Build and maintain internal Python platform libraries and tooling to improve developer experience. Drive runtime, dependency, testing, delivery, monitoring, and performance optimization for Python services (including GPU-enabled workloads). Collaborate cross-functionally to define an opinionated SDLC, support on-call rotations, and balance modern practices with risk-aware change. Enable scalable, low-latency distributed systems and provide AI/ML-facing platform capabilities.

Design and build full-stack applications that expose AI/ML insights. Develop backend services in Python, RESTful APIs, and containerized microservices. Build high-performance front-end interfaces with React/Vue/Angular. Implement cloud-native solutions on Google Cloud or Azure, manage relational and NoSQL databases, apply testing and CI/CD, and participate in Agile development and architecture sessions.

Senior iOS developer responsible for implementing native iOS features, improving user experience, participating in agile squads, conducting code reviews, troubleshooting customer issues, and helping modernize backend services on AWS. Collaborates with product and UI teams and documents technical knowledge while following best practices.

Design and implement scalable backend and distributed systems for a marketing intelligence platform. Build near-real-time ingestion and processing, scale an incrementality/experimentation product, integrate AI-powered workflows, improve data ingestion/exports and connection-state systems, and contribute frontend components to deliver end-to-end product experiences.

Design and implement durable, fault-tolerant AI orchestration and backend systems using Temporal and agentic ReAct patterns. Deliver features end-to-end with testing, CI/CD, monitoring, and observability; mentor engineers and collaborate with cross-functional teams to translate legal workflows into reliable AI-powered features.

Design and build backend systems and APIs for AI-driven products, ensuring scalability, reliability, and integration of ML models while collaborating with engineering and product teams.

As a Founding Staff Software Engineer, you will lead the design and development of robust backend systems and APIs, optimize large-scale data workflows, and mentor a growing engineering team.

Build and ship full‑stack features for transportation management and other client products. Design and implement APIs and UIs, collaborate with product and design, own delivery, write modular testable code, troubleshoot and iterate quickly, and mentor peers.