Top California Machine Learning Startups (419)

Deepgram is the leading voice AI platform for developers building speech-to-text (STT), text-to-speech (TTS) and full speech-to-speech (STS) offerings. 200,000+ developers build with Deepgram’s voice-native foundational models – accessed through APIs or as self-managed software – due to our unmatched accuracy, latency and pricing. Customers include software companies building voice products, co-sell partners working with large enterprises, and enterprises solving...

American medicine is the best in the world. But the American healthcare system is challenged by high administrative costs that burden patients, health systems, and insurance companies with unnecessary expenses. We are focused on addressing those challenges. We use GenAI to improve the most pressing financial pain points in the revenue cycle. We’re one of the first companies to deploy GenAI...

Founded in 2020 by George Sivulka and backed by Peter Thiel and Andreessen Horowitz, Hebbia powers investment decisions for BlackRock, KKR, Carlyle, Centerview, and 40% of the world’s largest asset managers. Our flagship product, Matrix, delivers industry-leading accuracy, speed, and transparency in AI-driven analysis. It is trusted to help manage over $15 trillion in assets globally. We deliver the intelligence that...

Bellagent is an enterprise-level AI agent platform built to automate everyday business operations with zero-touch integrations that connect instantly to more than 1,300 applications. Launched in 2025 by Proactifi Inc., and headquartered in Chicago, the platform is built for practicality with industry-leading compliance and security standards, enabling organizations to deploy AI agents without friction from day one. Bellagent’s mission to...

Domino Data Lab powers model-driven businesses with its leading Enterprise AI platform trusted by over 20% of the Fortune 100. Domino accelerates the development and deployment of data science work while increasing collaboration and governance. With Domino, enterprises worldwide can develop better medicines, grow more productive crops, build better cars, and much more. Founded in 2013, Domino is backed by...

Our mission is to remove inefficiency from the foundation of AI. By combining new research in information theory, probabilistic modeling, and distributed systems, we’re creating self-optimizing data infrastructure that continuously improves how information is represented and used by intelligent systems.

WorkWhile is an AI-powered next generation labor platform that helps businesses in light industrial, hospitality, and events achieve over 90% fill rates and reduce no-shows through AI and predictive machine learning. We ensure seamless shift execution with trained, on-demand workers supported by on-site leads, real-time performance monitoring, and a robust accountability system. Our worker-first model boosts retention through benefits like...

Alif Semiconductor is the industry-leading supplier of the next-generation Ensemble family of microcontrollers and fusion processors. The Ensemble family scales from single core MCUs to a new class of multi-core devices, fusion processors, that blend up to two Cortex-M55 MCU cores, up to two Cortex-A32 microprocessor cores capable of running high-level operating systems, and up to two Ethos-U55 microNPUs for...

People.ai delivers the industry’s leading ROI (Revenue Operations and Intelligence) platform. Using patented AI technology, it transforms business activity data into recommendations that increase the impact of Sales, Marketing, and Operations. Companies such as Zoom, New Relic and PTC rely on People.ai to increase marketing ROI and grow revenue. People.ai automatically captures and analyzes business activity data including email, contacts,...

Democratizing AI on the Modern Data Stack! The team behind PyG (PyG.org) is working on a turn-key solution for AI over large scale data warehouses. We believe the future of ML is a seamless integration between modern cloud data warehouses and AI algorithms. Our ML infrastructure massively simplifies the training and deployment of ML models on complex data. With over 40,000...

Arcee AI delivers purpose-built AI agents, powered by industry-leading small language models (SLMs) for enterprise applications. Their offering, Arcee Orchestra, is an end-to-end agentic AI solution that enables businesses to create AI agents for complex tasks. The solution makes it easy to build custom AI workflows that automatically route tasks to specialized SLMs to deliver detailed, trustworthy responses, fast.

Lark Health is a chronic disease prevention and management platform that uses a cognitive behavioral therapy framework, conversational AI, and connected devices to help people stay healthy and in control of their conditions. Lark's AI is continuously learning how to personalize the experience for the member and communicates via text-message-like interactions to monitor patients remotely, 24/7, while live nurses and...

AE is a software development, data science, and design agency. That part is common. The rest is extraordinary. Founded in 2016, AE has bootstrapped its way to 150+ individuals working to increase human agency through technology. No venture capital. No private equity. No outside shareholders. This allows a longtermist perspective for clients and employees that leads to unparalleled thought-partnership and...

CourtAvenue is an Operating Network of digital transformation companies that utilizes data, machine learning and emerging technologies to build powerful relationships between brands and consumers.

We are building a Limitless Learning Companion, starting with an AI-powered app for kids - Yeti Confetti Kids. Powered by an AI model that can ingest any curriculum, create real-time lesson plans, and then optimise for learning outcome change. Enriched with social-emotional learning goals, not addictive gratification. Don’t let anyone be the judge of your potential. Discover it yourself, while you explore and...

We are a leader in fraud prevention and AML compliance. Our platform uses device intelligence, behavior biometrics, machine learning, and AI to stop fraud before it happens. Today, over 300 banks, retailers, and fintechs worldwide use Sardine to stop identity fraud, payment fraud, account takeovers, and social engineering scams. We have raised $145M from world-class investors, including Andreessen Horowitz, Activant,...

Genesis Molecular AI – headquartered in Burlingame, CA, with a fully integrated laboratory in San Diego and offices in New York – is pioneering foundation models for molecular AI to unlock a new era of drug design and development. We are using a proprietary state-of-the-art generative and predictive AI platform called GEMS (Genesis Exploration of Molecular Space), to accelerate and...

XP Health is a modern vision care platform that is a virtual-first approach for eye care and eyewear that can work as a standalone benefit or alongside any vision insurance plans. Using artificial intelligence, augmented reality, customer-centric design, and care navigation, the XP Health platform provides employees and their families with access to high-quality, comprehensive vision care at significantly lower...

Kharon is a highly disruptive organization that navigates risk at the intersection of global security threats + international commerce. We take really complex data as it relates to global security and empower our clients to not only understand the risk associated with their potential business relationships but to operationalize that data so that they can make the best and most...

Encord is the data layer for physical AI. We're how the world's most ambitious AI teams turn messy, multimodal data into production systems - from humanoid robots to autonomous vehicles to smart infrastructure. 300+ teams including Toyota, Skydio, and Maxar rely on Encord to curate, manage, and align the data their models actually need. $110M raised. San Francisco, New York,...