Top California Machine Learning Startups (418)

Our mission is to remove inefficiency from the foundation of AI. By combining new research in information theory, probabilistic modeling, and distributed systems, we’re creating self-optimizing data infrastructure that continuously improves how information is represented and used by intelligent systems.

Deepgram is the leading voice AI platform for developers building speech-to-text (STT), text-to-speech (TTS) and full speech-to-speech (STS) offerings. 200,000+ developers build with Deepgram’s voice-native foundational models – accessed through APIs or as self-managed software – due to our unmatched accuracy, latency and pricing. Customers include software companies building voice products, co-sell partners working with large enterprises, and enterprises solving...

WorkWhile is an AI-powered next generation labor platform that helps businesses in light industrial, hospitality, and events achieve over 90% fill rates and reduce no-shows through AI and predictive machine learning. We ensure seamless shift execution with trained, on-demand workers supported by on-site leads, real-time performance monitoring, and a robust accountability system. Our worker-first model boosts retention through benefits like...

Domino Data Lab powers model-driven businesses with its leading Enterprise AI platform trusted by over 20% of the Fortune 100. Domino accelerates the development and deployment of data science work while increasing collaboration and governance. With Domino, enterprises worldwide can develop better medicines, grow more productive crops, build better cars, and much more. Founded in 2013, Domino is backed by...

American medicine is the best in the world. But the American healthcare system is challenged by high administrative costs that burden patients, health systems, and insurance companies with unnecessary expenses. We are focused on addressing those challenges. We use GenAI to improve the most pressing financial pain points in the revenue cycle. We’re one of the first companies to deploy GenAI...

Founded in 2020 by George Sivulka and backed by Peter Thiel and Andreessen Horowitz, Hebbia powers investment decisions for BlackRock, KKR, Carlyle, Centerview, and 40% of the world’s largest asset managers. Our flagship product, Matrix, delivers industry-leading accuracy, speed, and transparency in AI-driven analysis. It is trusted to help manage over $15 trillion in assets globally. We deliver the intelligence that...

Bellagent is an enterprise-level AI agent platform built to automate everyday business operations with zero-touch integrations that connect instantly to more than 1,300 applications. Launched in 2025 by Proactifi Inc., and headquartered in Chicago, the platform is built for practicality with industry-leading compliance and security standards, enabling organizations to deploy AI agents without friction from day one. Bellagent’s mission to...

Corgi is building the first full-stack AI financial infrastructure company. We are headquartered in San Francisco, with offices in Salt Lake City, Dallas, Chicago, and Atlanta.

The Future of Microsurgery is Robotics and AI. We are a visionary team striving to revolutionize the field of eye surgery by leveraging the most cutting-edge technologies available today. Our groundbreaking product, Polaris, leverages state-of-the-art robotics, advanced medical imaging, and AI to extend the capabilities of surgeons beyond their current limitations.

The proactive AI assistant built for high-velocity teams.

Hypersonix is the Enterprise AI Platform purpose-built for Ecommerce. It acts as an enterprise nervous system that senses and reacts to market conditions and customer demand for optimal results and profitable revenue. It looks at all available data to provide real-time, actionable intelligence. Hypersonix users take advantage of instantaneous changes in customer demand, supply chain fluctuations, inventory surpluses and shortfalls,...

Docyt is focused on helping small business owners significantly reduce operating costs and eliminate issues associated with manual and high-risk back office tasks. Tedious yet crucial back office processes like Accounts Payable, Bookkeeping and Accounting are fully automated using AI and machine learning. With Docyt’s AI based document-driven platform, small business owners can save thousands of dollars in penalties, late fees...

Zilliz is a leading vector database company for production-ready AI. Built by the engineers who created Milvus, the world's most popular open-source vector database, Zilliz is on a mission to unleash data insights with AI. The company builds next-generation database technologies to help organizations rapidly create AI/ML applications, and unlock the potential of unstructured data. By taking the burden of...

Founded in 2009, Knorex is a technology company that provides programmatic advertising solutions to marketers to simplify digital marketing to accelerate business growth. Knorex XPO, our flagship, helps marketers to connect in real-time with the desired audience worldwide through the industry's widest deep connectivity to leading marketing channels including social media, search, connected TVs/OTTs, video, audio, display/native, and email, all...

AiFi provides the most flexible AI platform that enables retailers to affordably deploy and scale autonomous shopping solutions across their businesses. Leveraging computer vision, AiFi adapts to existing store formats without the need for shelf sensors, and provides advanced tracking algorithms that can scale up to 10,000 square feet to support various shopper journeys such as an app, credit card,...

Let Deep Infra run your ML infrastructure. Just use our top AI models using a simple API or deploy your own model with us.

Freeform is deploying software-defined, autonomous metal 3D printing factories around the world, bringing the scalability of software to physical production. Our proprietary technology stack leverages advanced sensing, real-time controls, and data-driven learning to produce digitally-verified, flawless parts at unprecedented speed and cost. Our mission is to make the transformative power of 3D printing available to all industries at scale and...

Labelbox is the data factory for generative AI, providing the highest quality training data for frontier and task-specific models. Labelbox’s comprehensive platform combines on-demand labeling services with the industry-leading data labeling platform. The Boost labeling service is powered by the Alignerr community of highly-educated experts, who span all major languages and a diverse range of advanced subjects. They are available...

ArsenalBio is a privately held, programmable cell therapy company focused on the realization of solid tumor cell therapy to defeat cancer. Our discovery engine comprises precise CRISPR-enabled genome editing, integrated circuits incorporating logic gates for improved tumor targeting, and therapeutic enhancements enabling multiple pharmaceutical functions. With our programmable and computationally driven approach, we aim for enhanced and broader efficacy, increased...

Flagright sets the modern standard for AI-native transaction monitoring. The platform enables financial institutions to centralize detection, investigation, and reporting of suspicious activity, streamlining regulatory workflows and strengthening financial crime controls. A high-performance, no-code scenario builder with sub-second API response times powers real-time monitoring, supported by tailored rules, dynamic risk profiling, and simulation tools that reduce false positives and improve...