Top California Machine Learning Startups (429)

American medicine is the best in the world. But the American healthcare system is challenged by high administrative costs that burden patients, health systems, and insurance companies with unnecessary expenses. We are focused on addressing those challenges. We use GenAI to improve the most pressing financial pain points in the revenue cycle. We’re one of the first companies to deploy GenAI...

WorkWhile is an AI-powered next generation labor platform that helps businesses in light industrial, hospitality, and events achieve over 90% fill rates and reduce no-shows through AI and predictive machine learning. We ensure seamless shift execution with trained, on-demand workers supported by on-site leads, real-time performance monitoring, and a robust accountability system. Our worker-first model boosts retention through benefits like...

Domino Data Lab powers model-driven businesses with its leading Enterprise AI platform trusted by over 20% of the Fortune 100. Domino accelerates the development and deployment of data science work while increasing collaboration and governance. With Domino, enterprises worldwide can develop better medicines, grow more productive crops, build better cars, and much more. Founded in 2013, Domino is backed by...

Treeswift builds physical AI for labor. We use robotics and machine learning to help the people who do real work get more done, starting with the crews who keep the electric grid running,.

Our mission is to remove inefficiency from the foundation of AI. By combining new research in information theory, probabilistic modeling, and distributed systems, we’re creating self-optimizing data infrastructure that continuously improves how information is represented and used by intelligent systems.

Founded in 2020 by George Sivulka and backed by Peter Thiel and Andreessen Horowitz, Hebbia powers investment decisions for BlackRock, KKR, Carlyle, Centerview, and 40% of the world’s largest asset managers. Our flagship product, Matrix, delivers industry-leading accuracy, speed, and transparency in AI-driven analysis. It is trusted to help manage over $15 trillion in assets globally. We deliver the intelligence that...

Deepgram is the leading voice AI platform for developers building speech-to-text (STT), text-to-speech (TTS) and full speech-to-speech (STS) offerings. 200,000+ developers build with Deepgram’s voice-native foundational models – accessed through APIs or as self-managed software – due to our unmatched accuracy, latency and pricing. Customers include software companies building voice products, co-sell partners working with large enterprises, and enterprises solving...

Bellagent is an enterprise-level AI agent platform built to automate everyday business operations with zero-touch integrations that connect instantly to more than 1,300 applications. Launched in 2025 by Proactifi Inc., and headquartered in Chicago, the platform is built for practicality with industry-leading compliance and security standards, enabling organizations to deploy AI agents without friction from day one. Bellagent’s mission to...

building forklift automation systems using machine learning and shared autonomy

Vectara is an LLM-powered Answer as a Service. The platform provides a #chatgpt like service which enables you to have a conversation with your own data. Our 100% neural natural language understanding (NLU) technology provides radical increases in semantic relevance. Instead of a list of results ala legacy keyword-based systems, we provide a direct answer to the user's input prompt....

Proven at global web scale in production for modern data services, Alluxio is the developer of open source data orchestration software for the cloud. Alluxio moves data closer to big data and machine learning compute frameworks in any cloud across clusters, regions, clouds and countries, providing memory-speed data access to files and objects. Intelligent data tiering and data management deliver...

We help essential service industries grow on autopilot. Essential services power the real economy. Every one of us interacts with these industries repeatedly throughout our lives. But these large businesses face real-world constraints—human labor, external volatility, compliance, logistics, and physical infrastructure. Their operations are complex and often rely on outdated systems and manual workflows, and they can’t access the frontier technologies that...

Nimble enables your AI agents and teams to stream the precise intelligence they need from the live web, powered by infrastructure built to reliably access even the most complex, difficult-to-reach data.

Hugging Face is the leading open platform for AI builders. For researchers, Hugging Face is the place to publish models and collaborate with the community. For data scientists, it’s where you can explore over 300k off-the-shelf models for any machine learning task and create your own. For software developers, it’s where you can turn data and models into applications and features. Today,...

Crunchbase is a predictive intelligence solution that forecasts private market movements using the unique combination of live private company data, AI, and market activity data from 80M+ users. It helps people who are making bets in the private market — such as go-to-market (GTM) teams, investors, and wealth managers — move first and make more confident decisions. We are committed to...

The iSono Health has developed the world’s first AI-driven platform with an automated, portable, and wearable ultrasound to empower women and their physicians with early breast cancer detection and monitoring. Our patented compact ultrasound scanner captures 3D images by automatically scanning the whole breast volume in 2 minutes. The device connects to a smartphone/tablet/laptop. The data is transferred to a...

Craft illuminates the path to global supply chain resilience. We empower businesses to strengthen their supplier networks and supply chains with the industry's most trusted and comprehensive data fabric and advanced risk mitigation engine. Our easy-to-use platform provides 360-degree visibility to quickly explore and evaluate supplier networks, AI-driven insights to detect and mitigate disruptions, and collaborative tools to optimize supply...

Vidmob is the creative data company. Its AI-based software improves creative and media performance by helping brands and agencies derive their own custom creative best practices, and ensure that those learnings are applied across all flighted media. Vidmob’s approach to using creative data drives brand consistency, reduces creative and media waste, and increases overall business performance across the funnel. As...

Datawizz is revolutionizing data management with advanced synthetic data solutions. We help businesses unlock the power of their data while ensuring privacy and compliance. Our technology generates realistic synthetic data for machine learning, software testing, data enrichment, and augmentation—all within a click of a button. Enhance your data strategies with Datawizz and drive innovation securely and efficiently.

ArsenalBio is a privately held, programmable cell therapy company focused on the realization of solid tumor cell therapy to defeat cancer. Our discovery engine comprises precise CRISPR-enabled genome editing, integrated circuits incorporating logic gates for improved tumor targeting, and therapeutic enhancements enabling multiple pharmaceutical functions. With our programmable and computationally driven approach, we aim for enhanced and broader efficacy, increased...