Top California Machine Learning Startups (445)

Our mission is to remove inefficiency from the foundation of AI. By combining new research in information theory, probabilistic modeling, and distributed systems, we’re creating self-optimizing data infrastructure that continuously improves how information is represented and used by intelligent systems.

Founded in 2020 by George Sivulka and backed by Peter Thiel and Andreessen Horowitz, Hebbia powers investment decisions for BlackRock, KKR, Carlyle, Centerview, and 40% of the world’s largest asset managers. Our flagship product, Matrix, delivers industry-leading accuracy, speed, and transparency in AI-driven analysis. It is trusted to help manage over $15 trillion in assets globally. We deliver the intelligence that...

Deepgram is the leading voice AI platform for developers building speech-to-text (STT), text-to-speech (TTS) and full speech-to-speech (STS) offerings. 200,000+ developers build with Deepgram’s voice-native foundational models – accessed through APIs or as self-managed software – due to our unmatched accuracy, latency and pricing. Customers include software companies building voice products, co-sell partners working with large enterprises, and enterprises solving...

American medicine is the best in the world. But the American healthcare system is challenged by high administrative costs that burden patients, health systems, and insurance companies with unnecessary expenses. We are focused on addressing those challenges. We use GenAI to improve the most pressing financial pain points in the revenue cycle. We’re one of the first companies to deploy GenAI...

Treeswift builds physical AI for labor. We use robotics and machine learning to help the people who do real work get more done, starting with the crews who keep the electric grid running,.

Bellagent is an enterprise-level AI agent platform built to automate everyday business operations with zero-touch integrations that connect instantly to more than 1,300 applications. Launched in 2025 by Proactifi Inc., and headquartered in Chicago, the platform is built for practicality with industry-leading compliance and security standards, enabling organizations to deploy AI agents without friction from day one. Bellagent’s mission to...

Neurophos is an Austin-based semiconductor company developing high-performance, energy-efficient photonic AI inference chips. Instead of traditional electronic circuits, we use silicon photonics and an active, programmable metasurface to perform matrix multiplications at the speed of light. Our optical cells are 10,000x smaller than traditional photonic components, enabling unprecedented density for an optical system. As AI adoption accelerates, data centers face significant...

AiFi provides the most flexible AI platform that enables retailers to affordably deploy and scale autonomous shopping solutions across their businesses. Leveraging computer vision, AiFi adapts to existing store formats without the need for shelf sensors, and provides advanced tracking algorithms that can scale up to 10,000 square feet to support various shopper journeys such as an app, credit card,...

CourtAvenue is an Operating Network of digital transformation companies that utilizes data, machine learning and emerging technologies to build powerful relationships between brands and consumers.

Flai is an AI-powered platform for automotive dealerships that automates customer interactions, books appointments, and enhances engagement. Their AI assistants handle inbound calls, manage recalls, and integrate with dealership systems to streamline operations and improve lead management.

Lark Health is a chronic disease prevention and management platform that uses a cognitive behavioral therapy framework, conversational AI, and connected devices to help people stay healthy and in control of their conditions. Lark's AI is continuously learning how to personalize the experience for the member and communicates via text-message-like interactions to monitor patients remotely, 24/7, while live nurses and...

Mythic develops cutting-edge Analog Processing Units (APUs) utilizing unique analog compute-in-memory technology. This innovative approach aims to deliver highly energy-efficient and cost-effective AI inference solutions. By overcoming the memory bottlenecks inherent in traditional digital architectures, Mythic enables unparalleled performance-per-watt for AI workloads across diverse applications, including data centers, automotive, robotics, and defense industries.

Aquabyte is one of the few companies applying machine learning / computer vision to directly solve the world’s food sustainability issues. Fish farming is the #1 fastest growing sector of food production - a $180B worldwide industry. By improving fish farm efficiency, we help close the world’s impending protein deficit. We work on very challenging distributed image processing and machine learning...

HomeVision brings modern document understanding technology to enable more accurate and streamlined collateral review and underwriting for lenders, appraisal management companies, and others. HomeVision's MIRA platform can examine all aspects of an appraisal including all of the photos, maps, floor plans, and textual commentary. MIRA integrates with popular LOS and AMS platforms and external data sources like public records and...

AssemblyAI builds the best-in-class Voice AI models powering the next generation of voice applications. Our models serve 600M+ inference calls monthly, process 1M+ hours of audio daily, and power 2 billion+ end-user experiences. With thousands of customers including Granola, Fireflies, Figure AI, and CallRail, the company has real scale - processing over 2 million hours of audio daily and handling...

Eventual is building a Data Warehouse from the ground up that is designed to tackle the challenges of working with traditional data engineering and analytics alongside modern ML/AI workloads. Eventual has raised over $2.5M from investors including YCombinator, Array VC, Caffeinated Capital and top Silicon Valley executives and founders in companies such as Meta, Lyft and Databricks.

Nimble enables your AI agents and teams to stream the precise intelligence they need from the live web, powered by infrastructure built to reliably access even the most complex, difficult-to-reach data.

Alif Semiconductor is the industry-leading supplier of the next-generation Ensemble family of microcontrollers and fusion processors. The Ensemble family scales from single core MCUs to a new class of multi-core devices, fusion processors, that blend up to two Cortex-M55 MCU cores, up to two Cortex-A32 microprocessor cores capable of running high-level operating systems, and up to two Ethos-U55 microNPUs for...

Insitro is a data-driven drug discovery and development company.

Eluvio is transforming the management, distribution, and economics of premium video for content owners. The Eluvio Content Fabric is a global platform service that enables just-in-time, low-latency content distribution, monetization, and asset servicing directly to consumers. Content is delivered directly from source as on-demand streams, live streams, and dynamic sequences–without the use of separate transcoding services, content delivery networks (CDNs),...