Top California Biotech Startups (568)
We remove atmospheric carbon for a fraction of the cost while increasing crop yields. Our process is highly efficient, increases soil health, and repurposes post-industrial waste. Then we sell the carbon credits to companies and split revenue with our regenerative growers. With a world-class team leveraging expertise in soil chemistry, agronomy, geochemistry, machine learning, and logistics, we are engineering the...
Kardigan is a patient-driven heart health company that is modernizing cardiovascular drug development to deliver medicines that move patients beyond symptom management to functional cures. By matching critical disease drivers with treatment responders identified in clinical trials, Kardigan is developing a portfolio of medicines that modify the underlying cardiovascular disease pathophysiology to get patients closer to the cures they deserve....
Citrine Informatics is the award-winning materials informatics platform for data-driven materials and chemicals development. It won the 2017 World Materials Forum Start-up Challenge, the 2018 AI Breakthrough award as the "Best AI-based Solution for Manufacturing," and 2020-2021 Cleantech 100 honors. The Citrine Platform combines smart materials data infrastructure and AI, which accelerates development of cutting-edge materials, facilitates product portfolio optimization,...
Helping the brain work better with focused ultrasound. Treating neurological disorders today and enhancing human experience tomorrow.
Crinetics is a pharmaceutical company that develops much-needed therapies for people with rare endocrine diseases. We’re here for patients who are eager to find therapies that provide effective disease control and more simplicity in their lives. We partner with healthcare practitioners to ensure we’re solving real problems for them. And we build value in the company for investors by filling...
Septerna is on a mission to make the promise of future GPCR medicines a reality for patients. Combining the latest advances in biochemical, structural and computational drug discovery approaches, we have built an industrialized platform to precisely control and modulate GPCR biology and pharmacology to discover and develop new high-impact medicines. With our Native Complex™ platform, we are opening a...
Our mission is to make actionable information accessible to everyone at the time it matters. By making actionable information accessible to everyone in the world at the time it matters most, we are working to facilitate the early detection and prevention of disease, and empower people everywhere to live their best possible lives.
Empirico is a biotechnology company focused on the discovery and development of novel medicines which are designed to mimic naturally-occurring genetic variants that confer beneficial effects on health and disease. Empirico’s two foundational and proprietary technology platforms - the Precision Insights Platform™ for genetically-validated target discovery and siRCH™ for the discovery and development of siRNA medicines - are used separately...
We have always walked our own path, at Alector. That’s what led us to the bold thinking and fresh, new approach of empowering the body’s immune system to fight disease. Join us in our mission to eliminate neurodegeneration and cancer through immuno-neurology and immuno-oncology. We are developing a broad portfolio of programs, currently in various stages of clinical trials. Alector is based...
Headquartered in Fremont, CA, Paragon Genomics is a dynamic and growing company developing and commercializing breakthrough target enrichment solutions for Next-Generation Sequencing (NGS). We are building a team of passionate scientists, engineers and business professionals who thrive in a collaborative entrepreneurial environment. Our patented CleanPlex amplicon sequencing technology solves the urgent throughput and efficiency bottlenecks of targeted sequencing workflow and...
Tahoe Therapeutics (formerly Vevo Therapeutics) is a biotechnology company using its in vivo drug discovery platform and next generation AI models to uncover better drugs for more patients. The company’s Mosaic platform is the first to make in vivo data generation scalable, with single-cell precision, to capture in vivo context of disease at the first step of drug discovery and...
We are building reversible cryopreservation technology to solve the organ procurement and matching problem. Cryopreservation is already essential to modern medicine — powering IVF and life-saving stem cell therapies. Now, we’re extending this technology to whole human organs — transforming hours of viability into weeks, or months, however long is necessary — so that no donated organ is lost to logistics,...
Niagen Bioscience (NASDAQ:NAGE), founded in 1999 and formerly known as ChromaDex, is the global authority on nicotinamide adenine dinucleotide (NAD+), dedicated to advancing healthy-aging science. Our world-renowned scientists collaborate with independent investigators from leading universities and research institutions worldwide to explore the full potential of NAD+, a vital coenzyme found in every cell that declines with age and everyday stressors. Setting...
Structure Therapeutics is a science-driven clinical-stage biopharmaceutical company focused on discovering and developing innovative oral small molecule treatments for chronic metabolic and cardiopulmonary conditions with significant unmet medical needs. Utilizing its next generation structure-based drug discovery platform, Structure Therapeutics has established a robust GPCR-targeted pipeline, featuring multiple wholly-owned proprietary clinical-stage small molecule compounds designed to surpass the scalability limitations of...
Pulse Biosciences is the inventor and sole proprietor of Nanosecond Pulsed Field Ablation™ (nsPFA™) technology. We are committed to health innovation that has the potential to improve and extend the lives of patients. Our proprietary Nanosecond Pulsed Field Ablation technology delivers nanosecond pulses of electrical energy to non-thermally clear cells while sparing adjacent non-cellular tissue. The people at Pulse Biosciences are...
We sequence whole plasmids, amplicons, whole bacterial genomes, and colonies overnight, without the need for primers and minipreps. Plasmidsaurus is on a mission to accelerate new cures and promote a healthier planet by unlocking new levels of productivity in scientists using DNA tools to bring their ideas to life. The company’s DNA sequencing services are used daily by thousands of innovators,...
Encoded Therapeutics is creating one-time, disease-modifying gene therapies for pediatric central nervous system (CNS) disorders with its cell-selective targeting and regulation platform. The Encoded approach offers potentially unprecedented gene specificity and cell selectivity to unlock novel opportunities by targeting a range of disease mechanisms. Encoded’s technology is compatible with any delivery system to control where and when therapeutic transgenes are...
Tr1X Inc. (pr. "Trix") is a biotechnology company dedicated to the development of novel cellular immunotherapies for patients with autoimmune and inflammatory diseases. The Company uses its proprietary platform for the generation of first-in-class cell therapy products aimed at rebalancing the immune system and restoring homeostasis, leading to long term tolerance. Tr1X is headquartered in La Jolla, CA.
Orca Bio is a clinical-stage biotechnology company developing a pipeline of high precision allogeneic cell therapy products that are designed to safely replace patients’ diseased blood and immune system with a healthy one. Our manufacturing platform sorts donor blood with single-cell precision and a high level of purity and speed, enabling us to create proprietary, optimal therapeutic mixtures of immune...
