Top California Healthtech Startups (878)
We're Mochi Health, a pioneering force in obesity medicine dedicated to building personalized, clinically-backed weight care solutions. We're on a mission to empower patients with one-on-one virtual care and proven pharmaceutical treatments. We recognize that every body is unique, and believe weight loss plans should be, too. With over 100 million individuals struggling with obesity and 15 million already using GLP-1 prescriptions,...
Axle Health builds scheduling and workforce management software to empower in-home healthcare providers to deliver exceptional, personalized care right where patients feel most comfortable—at home. Some of the biggest providers in the country use our software (like Cityblock Health and Grandcare) to improve the utilization of their field teams by 17%+, and automate the operational burden of scheduling and dispatching. Our platform...
American medicine is the best in the world. But the American healthcare system is challenged by high administrative costs that burden patients, health systems, and insurance companies with unnecessary expenses. We are focused on addressing those challenges. We use GenAI to improve the most pressing financial pain points in the revenue cycle. We’re one of the first companies to deploy GenAI...
Revero is an online clinic for treating chronic conditions with a root-cause approach. Revero delivers personalized treatments for autoimmune and metabolic conditions through nutrition therapy and remote medical care, with the goal to help patients lower blood sugar, improve metabolic health, reduce inflammation, restore gut health, and lose weight.
At Orchard Therapeutics, our vision is to end the devastation caused by genetic and other severe diseases. We aim to do this by discovering, developing and commercializing new treatments that tap into the curative potential of hematopoietic stem cell (HSC) gene therapy. In this approach, a patient’s own blood stem cells are genetically modified outside of the body and then...
Brain monitoring is not easily accessible, interpretable or actionable. We're going to fix this, and we'd like you to help. With improved access to brain data and the right tools to act on it, clinicians could intervene in real-time, match life-altering therapies to the patients they benefit most, and treat previously untreatable neurological and psychiatric diseases. Beacon is building an...
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ArsenalBio is a privately held, programmable cell therapy company focused on the realization of solid tumor cell therapy to defeat cancer. Our discovery engine comprises precise CRISPR-enabled genome editing, integrated circuits incorporating logic gates for improved tumor targeting, and therapeutic enhancements enabling multiple pharmaceutical functions. With our programmable and computationally driven approach, we aim for enhanced and broader efficacy, increased...
Cellanome is a biotechnology company developing a multi-omics platform to measure biology at an unparalleled resolution and scale. Their technology enables scientists to see cells in action, track behavior and molecular changes over time, and connect morphology and function with underlying molecular profiles.
At Caresyntax, we are dedicated to making surgery safer and smarter. Our mission is to converge AI-powered software, devices, and clinical services to help our customers improve surgical outcomes. Our platform, an enterprise-grade surgical intelligence system, is vendor-neutral and equipped with proprietary software, hardware, and advanced AI capabilities. It can ingest and analyze data throughout the surgical workflow, including EMR,...
Alpine enables provider groups across the United States to transform the experience for seniors and providers by leveraging capital, technology, and expertise in whole person care.
We are a company dedicated to helping children reach their greatest potential. BTA specializes in providing applied behavior analysis (ABA) therapy to children with neurodivergent conditions and behavioral disorders. Each client we work with is unique, and their treatment programs reflect that. Our team of clinical experts evaluates clients and develops the best-personalized treatment programs for every child. Clinical programs...
Angel City VA is a U.S.-based healthcare outsourcing company founded in 2025, specializing in virtual assistant services for medical professionals. Headquartered in Los Angeles, California, the company provides HIPAA-compliant support across administrative tasks, patient coordination, billing, and EMR management. With a mission to streamline healthcare operations and reduce burnout, Angel City VA empowers clinics and solo practitioners to focus on...
Last year at Loka, our remote team of engineers, developers, and designers helped route out hate speech on Twitter, eliminate $1 billion in food waste, launch 4 projects in LokaLabs™ (our own incubator), accelerate 3 startups to acquisition, and still enjoyed every other Friday off. We are using modern technologies to support an incredible variety of meaningful projects, while...
XP Health is a modern vision care platform that is a virtual-first approach for eye care and eyewear that can work as a standalone benefit or alongside any vision insurance plans. Using artificial intelligence, augmented reality, customer-centric design, and care navigation, the XP Health platform provides employees and their families with access to high-quality, comprehensive vision care at significantly lower...
As a sonographer-led company, we know the impact of every scan. At BB Imaging, we bring precision-driven ultrasound to underserved communities by partnering with healthcare systems in need of flexible, scalable solutions built for better outcomes. We believe in a future where everyone—regardless of geography or socioeconomic status—has access to high-quality imaging and a higher standard of care. Our sonographers are...
Neptune Medical is a venture capital funded medical device start-up, located in the Silicon Valley town of Burlingame. We develop, manufacture, and commercialize high-volume, high clinical utility medical devices initially commercialized for gastroenterology, see our website below. Our patent-pending technology is foundational and will have a broad impact across multiple additional clinical areas, including including GI, cardiovascular, pulmonary, and neuro....
Our solutions are created to eliminate the financial complexity of healthcare. People work here because they deeply care about making an impact within the healthcare revenue cycle. Our mission is to build a waste-free healthcare transaction—a cleaner, simpler interaction between providers, payers, and patients. We will leave the waste exhaust behind. We're here to replace ambiguity with clarity, fragmentation with...
EHR-integrated pathways, analytics, and scoring tools. AgileMD is a web, mobile, and EHR-integrated application that provides clinicians fast access to guidelines, protocols, and reference information. With AgileMD, care providers improve the quality of care, reduce unnecessary utilization, and lower the risk of medical error. - Rock Health v2 - Y Combinator Summer 2011 - Winner of Chicago Biotech Consortium Business...
Our mission at Erasca is embedded in our name: To erase cancer. Energized by recent scientific discoveries and advances in drugging various biological drivers of cancer, we are committed to solving oncology’s hardest problems. We have assembled a proven team and joined forces with world-class collaborators who embrace our ambitious goals.

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