Top California Chemical Startups (21)
General Matter is an American nuclear-fuel startup founded in 2024 dedicated to restoring domestic uranium enrichment capabilities. The company focuses on producing low-enriched uranium (LEU) and high-assay low-enriched uranium (HALEU) to reduce U.S. dependence on foreign suppliers and support the deployment of advanced nuclear reactors, aiming to ensure energy independence and national security.
At Visolis, we use synthetic biology to manufacture high performance materials. Our systems approach integrates innovations in synthetic biology, chemical catalysis and process scale-up to enable new bio-based manufacturing platforms. Our unique bio-based process enables us to achieve true carbon-negative chemical synthesis. Visolis is located in Hayward, CA and Geleen, Netherlands, with close collaborations with Lawrence Berkeley National Lab, Pacific Northwest...
MACH-10 is an automotive protection company that delivers mobile, aerospace-grade ceramic coating services for vehicles. Its nano-ceramic formula chemically bonds to paint to provide gloss, hydrophobic performance, UV and chemical resistance, and protection lasting years or the vehicle’s lifetime. Certified technicians perform preparation, polishing, and coating at customers’ homes or offices, with packages supported by CARFAX registration, warranties, and annual...
Valdera is a sourcing platform for chemicals and raw materials. Our technology empowers companies to find the specialized inputs and formulations they need to build the future of sustainable & branded products.
ZymoChem is breakthrough science for a fossil-free future. We accelerate the transition to a real-zero economy by developing bio-based materials for everyday products. Are you interested learning more about how our high performance biomaterials are replacing petrochemical ingredients? We are seeking candidates who are motivated by science & innovation and have a passion to push the boundaries of materials performance. We are...
Rhoic makes on-demand, on-site chemicals with a new class of programmable reactors using electric fields. These reactors produce critical industrial chemicals from abundant feedstocks like air and water without fossil fuel inputs or hazardous transport. Rhoic's near-term beachhead is the oxidizer supply chain for bipropellant spacecraft, specifically NTO, MON-3, and MON-25, which today flow from a single domestic source that...
Earth Friendly Products, maker of the ECOS brand, is a family-owned U.S. manufacturer of plant-powered laundry detergent and a wide range of sustainable cleaning products. Its cleaners are made with plant-derived ingredients and formulated to be safer for people, pets, and the planet. The company serves household and professional cleaning needs and pursues more responsible production through sustainability initiatives across...
Founded in 2014, Insight M is a consultative methane emissions management company driven by our unwavering commitment to scientific rigor and overall customer success. We are the energy industry’s leader in high-frequency aerial methane detection. Our team is comprised of leading methane scientists, engineers, and strategists whose sole focus is to create evidence-based solutions that empower our customers to achieve operational...
EMSL Canada, Inc. provides environmental and analytical laboratory services as part of EMSL’s testing network. Its capabilities cover food microbiology, nutritional and food-chemistry analysis, allergens, toxins, adulteration, and testing for environmental pollutants, asbestos, lead paint, metals, and chemicals. The company serves organizations requiring quality analytical results for clients needing specialized laboratory testing and has provided these services in Canada since...
The Environmental Working Group (EWG) is an American nonprofit activist group dedicated to protecting human health and the environment. It specializes in research and advocacy regarding agricultural subsidies, toxic chemicals, drinking water pollutants, and corporate accountability. By providing science-backed ratings and consumer guides, EWG empowers individuals to make informed choices to live healthier lives and promote a healthier environment for...
Cement is responsible for about the same amount of greenhouse gas emissions as all of the cars on the road today worldwide. Cement has been widely considered one of the most difficult materials to decarbonize and has even been called out as the reason why we need point-source CCS. We have invented a way to make carbon-negative Portland cement that...
Volochem Inc. provides reagents, fine chemicals, medicinal chemistry building blocks, and small-molecule synthetic services for pharmaceutical and biotechnology companies. Its offerings include research compounds, custom synthesis, medicinal chemistry support, scale-up, sourcing, and project- or FTE-based engagements. The company serves synthetic organic chemists, life-science researchers, medicinal chemistry teams, and pharmaceutical R&D organizations from operations in the United States and India.
eMolecules is driven to remove the fear, hurt and heartbreak of health problems worldwide, by enabling scientists to accelerate their research to find the cures. To achieve this eMolecules provides business intelligence data and integrated ecommerce software for screening compound, chemical building blocks and primary antibody supply chains. These tools combined with their acquisition, aggregation and analytical services greatly empower...
Sylvatex (SVX) is an advanced manufacturing technology company that collaborates with electric vehicle (EV) battery manufacturers. Our proprietary waterless process produces cathode active material (CAM) using fewer steps and less energy. We are addressing the core of the EV battery scaling challenges: cost, supply, and carbon footprint. SVX process is chemistry agnostic working with any cathode material for manufacturers affording...
CloudSDS is a cloud-based Safety Data Sheet (SDS) and chemical inventory management platform designed to help organizations improve workplace safety, regulatory compliance, and operational efficiency. We provide businesses with a centralized system to manage SDS documents, hazardous chemical inventories, GHS labeling, employee safety training, and compliance reporting across multiple facilities. Our software helps EHS teams streamline OSHA HazCom compliance, reduce manual...
Lygos is a pioneering sustainable specialty chemicals company, leading the world’s transition toward better, cleaner, and more sustainable products. We have built a proprietary and fully integrated platform of the most advanced technologies across synthetic biology, industrial chemistry, and application development to rapidly deliver market relevant solutions to some of the world’s biggest sustainability challenges. With a pipeline of high-performing,...
Ammobia is developing Haber Bosch 2.0 - a process for clean ammonia production. We leverage advances in materials science and catalysis to produce green ammonia at low cost. Our process and systems work across production scales, enabling ammonia as a clean chemical, fertilizer, and energy carrier for a decarbonized future Ammobia was founded by Karen Baert and Tristan Gilbert, recognized by...
Hypex Bio Explosives Technology AB is a Swedish industrial technology company developing and commercializing patented hydrogen peroxide-based, nitrate-free emulsion explosives for mining, construction, tunneling, and quarrying. Its platform includes production plants, charging equipment, transfer systems, and proprietary chemical inputs. The company supplies products in Scandinavia and licenses technology to international partners, aiming to reduce emissions, toxic byproducts, and operational risks.
































