Top Machine Learning Jobs in St. Louis, MO

Own product areas for an autonomous banking platform, translating backend capabilities (APIs, async workflows, ML) into user-facing features. Conduct customer discovery, define technical requirements and acceptance criteria, prioritize backlog, partner with engineering on scoping and de-risking, and validate outcomes using feedback loops and analytics.

Lead the Product and Design organization, define product vision and roadmaps, prioritize strategic investments, and align cross-functional teams to deliver safe, scalable robotic delivery experiences. Build and develop high-performing product and design teams, champion user-centered design, guide data-driven decisions, and translate complex robotics, hardware, software, and operational capabilities into customer value. Partner with executive leadership across Engineering, Operations, Safety, Policy, and Business Development to drive commercialization and growth.

Lead performance marketing data science initiatives focused on lead segmentation, bidding optimization, targeting, and marketing spend allocation. Develop and deploy production-ready machine learning systems, establish research and ML operations roadmaps, build monitoring frameworks, and identify high-impact opportunities. Partner with engineering, marketing, vendors, and executives while mentoring data scientists and machine learning engineers and promoting rigorous, maintainable, and reproducible practices.

Build and deploy AI agents, intelligent applications, scalable backend services, APIs, and full-stack solutions. Integrate large language models, AI services, data platforms, and external APIs into customer-focused products. Collaborate with engineering, product, and cross-functional teams while contributing to cloud-native applications, data pipelines, distributed systems, testing, deployment, and production operations.

Leads AI presales strategy, customer advisory, technical solution architecture, and team development. Translates business needs into AI use cases, prototypes, business cases, roadmaps, and repeatable offerings. Partners with sales, engineering, consultants, and technology vendors to support complex pursuits, executive briefings, demonstrations, proofs of concept, and AI business growth. Promotes responsible AI governance, tracks pipeline performance, develops thought leadership, and remains hands-on in high-impact customer engagements.

Lead and manage the underwriting and credit risk model validation team, perform hands-on independent validations of complex ML models, assess data integrity and performance, identify and remediate model weaknesses, partner on MRM framework improvements, and coordinate with audit, compliance, and controls to meet regulatory standards.

Drive new enterprise revenue and customer expansion by selling AI-powered SaaS solutions. Manage complex 6–12 month sales cycles, build executive relationships, develop value propositions, maintain pipeline accuracy, lead virtual account teams, and close high-value deals. Translate technical AI capabilities into measurable business outcomes, guide customer adoption, collaborate with marketing, product, and customer success teams, and exceed quarterly pipeline and revenue targets.

Own Sophos EDR strategy, roadmap, technical product development, AI-powered experiences, and go-to-market execution. Translate customer needs, threat research, telemetry, competitive intelligence, and business goals into product priorities. Partner with engineering, security operations, threat research, marketing, sales, and customer success to deliver endpoint detection, investigation, threat hunting, response, reporting, and XDR/MDR upgrade capabilities while driving adoption, revenue, and customer outcomes.

Architect and prototype scalable solutions for Twilio’s emerging technologies experimentation team. Lead AI, machine learning, and LLM-driven initiatives; guide technical direction; mentor engineers across the US and India; align prototypes with business goals; and ensure enterprise architecture, scalability, extensibility, and production readiness. The role requires extensive architecture or principal engineering experience, cloud expertise across AWS and Azure, full-stack development knowledge, database expertise, and strong technical leadership.

Annotate and label data accurately according to project guidelines, conduct quality checks, provide feedback on annotation tools and processes, collaborate with project teams, maintain efficiency, and identify issues for resolution. The role requires strong attention to detail, critical thinking, adaptability, communication skills, and comfort with repetitive computer-based work.

Lead the development of machine learning systems for Cedar Pay's Personalization Engine, manage ML engineers, and ensure ML model effectiveness.

Own the design vision and execution for experimental AI-powered learning tools co-created with teachers and researchers. Design teacher- and student-facing products, create flows, wireframes, interaction designs, and functional prototypes, and facilitate collaboration across educators, researchers, engineers, and data scientists. Conduct usability testing and validate research hypotheses while navigating ambiguity, data-heavy workflows, and uncertain AI/ML-enabled features.

Architect and scale cloud-based ML infrastructure supporting large-scale training, massive datasets, model development, and customer services. Own platform design, implementation, deployment, monitoring, reliability, cost optimization, and usability. Collaborate with data science, product, and operations teams, solve complex distributed-systems challenges, and mentor engineers while driving technical innovation.

Manage paid social campaigns and full-funnel strategies across Meta, LinkedIn, TikTok, Pinterest, Snapchat, and other paid channels. Oversee client accounts, analyze performance, identify growth opportunities, build client relationships, and collaborate with SEO, creative, and analytics teams. Contribute to thought leadership, coach associates, maintain quality standards, and explore automation, AI, and LLM search visibility initiatives.

Own the strategy, execution, customer success, and go-to-market for Oscilar’s Device and Behavior product. Lead development of SDKs, signal pipelines, behavioral biometrics, agentic identity signals, data networks, foundation-model capabilities, and analyst experiences. Partner with sales and customers to drive adoption, shape product positioning, and deliver a device intelligence and digital identity platform for fraud, onboarding, authentication, and risk decisions.

Develop and maintain pricing and predictive models for credit insurance products. Analyze claims, loss ratios, portfolio performance, profitability, credit risk, and economic scenarios. Recommend pricing actions, support forecasting and reserves, evaluate underwriting strategies, and partner with underwriting, finance, claims, data science, and technology teams. Ensure model governance, documentation, and actuarial standards compliance.

Staff-level ML and agent systems engineer responsible for production model lifecycles, multi-step agentic systems, evaluations, retrieval and context engineering, and model cost and latency optimization. The role owns technical direction for Code Understanding products, improves model and agent quality, establishes evaluation and monitoring standards, mentors engineers, collaborates with customers, and delivers reliable AI-powered developer experiences at enterprise scale.

Designs, builds, and operationalizes enterprise AI, generative AI, machine learning, and agentic AI solutions. Develops integrations, orchestration services, reusable tooling, deployment pipelines, monitoring, and governance controls. Partners with architecture, platform, data, and product teams to deliver scalable, secure, compliant AI capabilities across the organization.

Designs and governs enterprise AI architecture, including generative AI, agentic workflows, RAG, orchestration, integrations, governance, security, compliance, and AI operations. Establishes scalable reference architectures, platform strategies, responsible AI guardrails, lifecycle management, monitoring, and cost controls. Partners with enterprise architecture, engineering, data, and product teams to drive secure AI adoption across cloud services, APIs, and enterprise platforms.

Owns the strategy, roadmap, requirements, backlog, positioning, and lifecycle execution for proprietary software products. Partners with engineering, UX, QA, architecture, data operations, and project management teams in an Agile environment. Conducts market and competitive analysis, supports product launches, creates AI prototypes, develops client-facing content, and contributes to RFP responses. Requires strong technical, product leadership, communication, prioritization, and stakeholder-management skills.

Lead and transform the Fraud Intelligence Team by designing scalable operating models, QA and measurement frameworks, and talent programs. Drive labeling quality, operational metrics, and fraud prevention impact; convert frontline fraud observations into insights for Product, R&D, Analytics, and GTM; leverage AI, automation, and tooling; and serve as a cross-functional fraud subject-matter expert while developing early-career talent and measurable business outcomes.

Build rigorous ROI analyses, value models, and business cases that translate AI ranking performance into revenue, margin, and cost-to-serve outcomes. Present analyses to CFOs, procurement teams, and other economic buyers; support sales pursuits; create reusable value-selling frameworks; tailor models to customer economics; and collaborate with product, data science, and customer teams to validate benchmarks and deployment results.

Own the full Global System Integrator partner lifecycle, including sourcing, agreements, joint go-to-market motions, enablement, delivery planning, and performance optimization. Build relationships across major GSIs such as Accenture, Deloitte, Bain, BCG, Slalom, and IBM. Collaborate with sales, product, and engineering teams to generate partner-sourced and influenced pipeline and revenue. Develop the GSI strategy, playbook, and operating processes for Sequen’s growing AI business.

Drive revenue retention and account growth across a portfolio of advertising clients. Responsibilities include developing account growth plans, managing forecasts and pipelines, identifying upsell and cross-sell opportunities, fostering product adoption, delivering data-driven campaign insights, leading QBRs, and coordinating Analyst, AdOps, Product, and Creative teams to resolve issues and achieve client outcomes.

Own strategic enterprise customer relationships, driving adoption, retention, measurable value, and expansion. Lead success reviews and executive engagements, translate supply chain challenges into solution strategies, build prototypes in Lyric Studio, train customer teams, coordinate forward-deployed engineers, partner with Sales on growth opportunities, and relay customer needs to Product and Engineering. The role requires deep supply chain expertise, technical fluency in modeling, planning, or AI/ML, and strong executive relationship skills.