Top Cyber Security Jobs in St. Louis, MO

Manage security operations and lead a security engineering team defending endpoints, SaaS, infrastructure, and corporate systems. Serve as senior Incident Commander, oversee detection and response using CrowdStrike, conduct cybersecurity risk assessments, and improve vulnerability, patch, access, and configuration management. Build detection coverage across endpoint, identity, SaaS, and cloud signals while partnering with AppSec and technical leaders. Lead the company’s AI security strategy and develop specialized security capabilities.

Conduct third-party security assessments, evaluate vendor controls, document risk findings, and automate governance workflows using Python and coding tools. Configure integrations across ticketing, GRC, and vendor-management platforms; develop risk dashboards and reporting; and partner with Procurement, Legal, Engineering, IT, Compliance, and Privacy. The role also supports security governance process improvements and applies frameworks including NIST, ISO 27001, SOC 2, and PCI DSS.

Lead end-to-end Application Security product and program: set strategy, prioritize roadmap, ship AI-powered threat modeling and code-evaluation surfaces, enable secure-by-design SDLC, enforce CI/CD gates, drive vulnerability prioritization/remediation, establish governance and metrics, and align security initiatives with engineering and executive stakeholders.

Lead design and implementation of secure global network infrastructure. Architect security standards, conduct threat modeling and network assessments, build security automation and tooling, integrate controls with SDN/BGP/MPLS platforms, support incident response, and mentor engineering teams to maintain resilient, observable network security posture.

Lead product security initiatives for cloud, AI, and enterprise platforms. Responsibilities include threat modeling, security architecture reviews, identifying systemic weaknesses, developing secure-by-design guidance and reference architectures, advising engineering and product leaders, leveraging AI and automation for scalable security assessments, investigating emerging attack paths, mentoring teams, and improving security review methodologies and tooling.

Lead complex cloud, identity, supply-chain, and nation-state security investigations. Perform root-cause analysis, threat hunting, blast-radius assessment, attribution, and incident response across Microsoft telemetry. Operationalize intelligence into queries, detections, playbooks, and platform fixes; investigate adversary tradecraft; use AI-assisted tooling; produce executive-ready reports; and mentor peers in advanced investigations, forensics, and reverse engineering.

Leads Windows security assurance across compliance, risk assessment, threat modeling, vulnerability research, and security tooling. Partners with engineering and product teams to translate security requirements into controls, execute scalable risk-based reviews, coordinate cross-team initiatives, and deliver measurable security improvements across the product lifecycle.

The Information Security Analyst will manage security operations, penetration testing, antivirus and SIEM tools, security assessments, AI-system risk evaluations, business continuity improvements, and compliance frameworks including SOC 2, NIST, and CJIS. The role also delivers security training, evaluates vendors, responds to security questionnaires and RFPs, and partners with IT, engineering, sales, and product teams. U.S. citizenship and FBI fingerprint and background checks are required.

Leads information security governance, risk, and compliance activities, including risk assessments, risk register management, remediation, security metrics, HITRUST and SOC 2 audits, client questionnaires, control documentation, and third-party risk management. Collaborates with IT, Privacy, Compliance, business stakeholders, and auditors to maintain healthcare data security and regulatory compliance.

Lead strategy to define and scale technical skilling for Microsoft's global Security Solutions Specialist community. Use sales and field data, market intelligence, and AI-enabled analytics to identify capability gaps, design skilling frameworks, drive adoption, measure impact, and advise senior leaders to accelerate security and AI-driven customer outcomes.

Conduct advanced vulnerability research across Microsoft products, cloud services, and open-source ecosystems. Develop scalable automation, AI-driven systems, and security tooling for vulnerability discovery and remediation. Lead offensive security assessments, analyze emerging attack techniques, collaborate with engineering and security teams, and publish technical findings influencing large-scale software systems.

Administer and enhance enterprise data security platforms, including SecuPi, while implementing access controls, masking, encryption, tokenization, monitoring, classification, and DLP across databases, cloud platforms, applications, and AI services. The role integrates security tools with IAM, PAM, SIEM, SOAR, and monitoring systems; troubleshoots complex environments; develops automation; investigates anomalous access; supports audits and incidents; and partners with infrastructure, cloud, database, application, privacy, and governance teams.

Drive technical pre-sales for data security: deliver demos/PoCs, lead hands-on workshops, design secure architectures, resolve technical blockers, advise on data governance and AI platform security, and represent Microsoft in developer communities.

Lead cloud security strategy and engineering across AWS infrastructure, applications, data, Kubernetes, CI/CD, and cloud-native systems. Design security controls for identity, networking, workloads, secrets, monitoring, and vulnerability management; automate guardrails; assess broader risks and attack paths; guide architecture and incident response; define security metrics; and influence engineering teams through technical leadership and communication.

Lead corporate security investigations and incident response across identity, endpoints, SaaS, email, and security platforms. Improve detection, response, Zero Trust controls, automation, and incident readiness. Conduct vendor security assessments, support customer security questionnaires, document risk decisions, and collaborate with Security, IT, Engineering, Legal, GRC, Procurement, Sales, and Customer Success teams.

Owns IT systems administration and security operations for a fully remote workforce. Responsibilities include managing Microsoft 365 and Google Workspace, endpoint and identity platforms, security tools, access controls, threat monitoring, incident response, vulnerability management, compliance evidence, disaster recovery, vendor relationships, reporting, and operational roadmaps.

Owns the architecture and technical roadmap for the Ping Identity platform. Designs enterprise SSO, MFA, identity governance, application integrations, RBAC and ABAC frameworks, lifecycle management, and cloud or hybrid deployments. Leads migration and multi-region availability strategies while producing architecture designs, solution blueprints, integration standards, and audit-ready runbooks.

Manage SOC 1, SOC 2, and ISO 27001 compliance programs, including internal and external audits, control enforcement, corrective actions, and policy updates. Monitor security alerts, support incident investigations, coordinate penetration testing, and administer password and phishing management systems. Lead security awareness initiatives, advise stakeholders, collaborate with Legal on encryption regulations, and drive continuous improvements to the organization’s information security posture.

Security Engineer responsible for application security, vulnerability and threat management, cloud and Kubernetes security, DevSecOps tooling, incident response, forensic analysis, and secure system architecture. The role integrates security testing into CI/CD pipelines, automates security tasks, supports IAM and cryptographic key management, and collaborates with engineering teams to strengthen security processes and tooling.

Leads complex digital forensics and incident response engagements, including ransomware, APT, nation-state, insider threat, host and network forensics, malware triage, cloud investigations, and threat attribution. Provides technical oversight, client leadership, methodology development, mentorship, tooling improvements, pre-sales support, and external thought leadership. Participates in on-call coverage and supports high-severity incident surges.

Designs, deploys, configures, migrates, and troubleshoots Palo Alto Networks security infrastructure in customer environments. Responsibilities include firewall, Panorama, Prisma, Strata Cloud Manager, and GlobalProtect implementation; migration from legacy platforms; routing and switching support; change-window execution; technical design and migration documentation; post-deployment stabilization; and communication with customers, account teams, and engineering. Travel to customer sites and evening, overnight, or weekend maintenance windows may be required.

Supports the deployment, configuration, integration, testing, migration, and troubleshooting of Palo Alto Networks, Zscaler, and other network security technologies for enterprise customers. Assists consultants with customer discovery, design workshops, implementation activities, technical documentation, and solution validation. Communicates technical concepts to technical and non-technical stakeholders while developing expertise in cybersecurity consulting, firewalls, networking, SASE, and cloud security.

Leads software security for Cisco’s IT and Enterprise Operations portfolio. Responsibilities include portfolio risk management, secure architecture and design reviews, threat modeling, AI and LLM security, analysis of SAST/DAST/SCA findings, remediation guidance, security SME coordination, leadership influence, release risk presentations, and security engineering metrics. The role drives risk-based security outcomes across engineering, product, IT, and operations teams without direct authority.

Lead software security for Cisco’s IT and Enterprise Operations portfolio. The role owns security posture, threat modeling, secure architecture reviews, AI and LLM security, risk-based remediation, security metrics, and release risk reporting. It partners with engineering, product, and IT leadership to drive security outcomes without direct authority, coordinate security subject-matter experts, and reduce security debt across cloud-native applications and enterprise platforms.

Build and operate cloud security controls across AWS, Azure, GovCloud, and secondary platforms. Responsibilities include IAM, encryption, secrets management, preventive and detective controls, PHI protection, logging pipelines, Terraform and CI/CD automation, remediation, application and vendor design reviews, and audit evidence for HITRUST, HIPAA, SOC 2, FedRAMP, and internal assessments.