Top Cyber Security Jobs in St. Louis, MO

Build and lead Motive’s globally distributed SOC, owning detection engineering, 24/7 incident response, threat hunting, intelligence, security analytics, endpoint protection, cloud and workload monitoring, and AI-driven automation. Establish operating models, coverage strategies, runbooks, telemetry platforms, incident command processes, and measurable detection and response capabilities across corporate and production environments.

Leads enterprise data security and information governance by building data intake, catalog, marketplace, classification, lineage, and access-control programs. Translates privacy and security requirements into technical controls, self-service workflows, and governance documentation. Partners with Legal, InfoSec, engineering, product, and data teams to support compliant data use, AI/ML initiatives, and regulatory requirements including HIPAA, GDPR, and CCPA. Measures adoption, turnaround times, and governance maturity across a global SaaS organization.

Lead security architecture and design reviews, define standards for protecting sensitive healthcare data, build automated defenses, guide security monitoring and incident response, translate complex objectives into engineering requirements, and mentor engineers through code and design reviews.

Monitor and analyze security events, lead incident response and employee investigations, conduct digital forensics, and communicate findings to technical, executive, legal, and compliance stakeholders. Build investigation scripts, runbooks, automated workflows, and security operations capabilities. Mentor engineers and support insider threat initiatives while collaborating across teams on cloud security and incident response.

The VP of Security will lead Engine’s security strategy, engineering, operations, AI security, corporate IT, and enterprise trust. Key priorities include building an AI security function, securing agent identities and AI gateways, leading AppSec, SecOps, and CloudSec, strengthening identity and access controls, managing corporate IT, supporting SOC 2 and PCI controls, and representing security to executives, the board, and enterprise customers.

Assess product and application architectures, develop threat models, identify security risks, and guide engineering teams on remediation. Promote security culture through training, mentoring, vulnerability management, and internal security initiatives. Build security tooling, automation, patterns, and workflows that embed secure-by-design practices across engineering. Partner with product managers, designers, and engineers to secure complex, large-scale cloud systems.

Protect corporate data through DLP implementation, tuning, alert review, false-positive reduction, and control optimization across web, endpoint, email, cloud, and SaaS environments. The engineer will review data protection programs, improve monitoring and blocking controls, collaborate with business partners, and use automation and emerging AI tools to strengthen security operations.

Lead Affirm’s enterprise AI security review program, threat model LLM and agentic systems, review code and configurations, and develop security guardrails, tooling, policies, and monitoring. Evaluate AI-enabled SaaS vendors, identify emerging vulnerabilities, support incident response, and lead cross-functional initiatives across Security, Engineering, Legal, Privacy, and Compliance. The role requires expertise in AI security architecture, threat modeling, IAM, cloud infrastructure, policy-as-code, and regulated enterprise environments.

Deploy and configure Rapid7 security products for post-sales customers, applying security best practices and documenting implementation decisions. Build custom dashboards, reporting workflows, integrations, and data pipelines using Python, SQL, and REST APIs. Support pre-sales scoping, resolve deployment challenges, collaborate across teams, improve internal delivery processes, and occasionally travel for customer engagements.

Performs information assurance and network security operations for Intelligence Community systems. Responsibilities include enforcing security policies, maintaining firewalls and gateways, conducting vulnerability remediation and forensic log analysis, hardening infrastructure, responding to incidents, supporting testing, and administering security documentation. The role requires experience with AWS, security tools, Unix/RHEL, PowerShell, network infrastructure, ACAS remediation, and DoD security compliance.

Lead software security for Cisco’s IT and Enterprise Operations portfolio. The role owns security posture, threat modeling, secure architecture reviews, AI and LLM security, risk-based remediation, security metrics, and release risk reporting. It partners with engineering, product, and IT leadership to drive security outcomes without direct authority, coordinate security subject-matter experts, and reduce security debt across cloud-native applications and enterprise platforms.

Leads and mentors a product security engineering team while remaining hands-on. Owns certification, accreditation, DISA STIG hardening, SOC 2, ISO 27001, audit readiness, vulnerability remediation, security tooling, and authorization initiatives. Coordinates with Compliance, Legal, Sales Engineering, and customers; tracks remediation SLAs and certification posture; establishes evidence collection processes; and translates technical security strategy into an executable roadmap.

Lead enterprise eDiscovery and insider-risk investigations by collecting, preserving, analyzing, and reviewing data from cloud infrastructure, endpoints, and repositories. Build AI-powered automation, correlate activity logs into investigative timelines, manage legal holds and governance policies, support digital forensics, and produce structured evidence packages for Security, Legal, HR, and investigative teams.

Administer and improve Workday and multi-platform HR security, including role-based access, security groups, access reviews, request approvals, audit support, governance documentation, and compliance controls. Evaluate elevated access requests, identify risks, resolve routine issues, coordinate remediation, and escalate complex decisions. Partner with HR, IT, Legal, and Compliance stakeholders to strengthen policies, processes, and least-privilege access across Workday, Peakon, UKG, Prism, and HR data platforms.

Lead and manage the information security and risk management function, overseeing staff, policies, projects, budgets, and security technology. Drive compliance with corporate and regulatory standards, deliver training and awareness, coordinate audits, and collaborate with stakeholders to implement security strategies and continuous process improvements.

Designs, implements, tests, and maintains enterprise IAM/SSO solutions. Troubleshoots authentication/authorization issues, integrates federation protocols (SAML/OAuth/SCIM), applies patches, trains stakeholders, and advises on IAM best practices and compliance.

Lead enterprise data security architecture to protect sensitive data across its lifecycle. Define strategies for encryption, key management, tokenization, masking, DLP, classification, database security, and Zero Trust. Advise execs and engineering on secure design patterns for data platforms (e.g., Starburst), cloud/on-prem systems, APIs, data pipelines, and AI/ML workloads. Develop roadmaps, evaluate technologies, mentor staff, and drive secure-by-design adoption across the organization.

Leads the enterprise data protection program and multidisciplinary security team. Owns strategy, architecture, roadmap, operations, and continuous improvement across DLP, data classification, monitoring, encryption, key management, digital rights management, and insider risk. Manages staff, budgets, policies, compliance, projects, and organizational change while communicating security risks and priorities to executive and cross-functional stakeholders.

Develops, deploys, configures, and maintains network security tools across on-premise and cloud environments supporting NGA networks. Responsibilities include managing IDS/IPS, NDR, packet capture, email security, and network visibility platforms; troubleshooting network protocols; maintaining architectures and inventories; evaluating emerging technologies; recommending upgrades; and briefing leadership. Requires active TS/SCI clearance, DoD cybersecurity certifications, and the ability to obtain a CI polygraph.

Designs, deploys, maintains, and improves enterprise endpoint security platforms and controls. Responsibilities include threat analysis, security event triage, endpoint infrastructure tuning, vulnerability management, policy enforcement, compliance reporting, technical documentation, and technology evaluations. The role supports security projects, mentors junior staff, collaborates with IT and leadership, and helps strengthen protection against emerging cyber threats across the enterprise.

Build and scale backend security platform services, including authentication, authorization, identity infrastructure, permission systems, and data models. Lead cross-team technical initiatives, standardize security solutions, collaborate with compliance and mission stakeholders, and influence architecture and engineering standards. The role requires strong system design, backend development, security expertise, technical leadership, and the ability to operate in sensitive environments.

Leads secure enterprise architecture design and GitLab Professional Services implementations across application security, cloud security, DevSecOps, identity, vulnerability management, and compliance. Guides SaaS, Self-Managed, and Dedicated deployment decisions; leads CI/CD, source control, and security-tool migrations; conducts risk assessments and threat modeling; supports pre-sales scoping and statements of work; coordinates cross-functional delivery; mentors consultants; and develops security enablement materials.

Lead complex security investigations across endpoint, identity, cloud, email, SaaS, and network environments. Own incidents through containment, remediation coordination, documentation, and post-incident review. Tune detections, queries, dashboards, workflows, and SOAR playbooks; improve SOC metrics, threat coverage, alert fidelity, and response processes. Partner on vulnerability and cloud-risk remediation, participate in global on-call rotation, use approved AI capabilities responsibly, and mentor analysts.

Leads the company’s information security operations and reports to the CISO. Oversees SIEM, threat detection, vulnerability management, penetration testing, incident response, SOC 2 Type II compliance, third-party risk, security awareness, cloud and endpoint security, and regulatory cybersecurity coordination. Manages security policies, breach readiness, tabletop exercises, KPIs, audits, and emerging technology evaluations while partnering with IT, infrastructure, compliance, regulators, and executive leadership.

Designs, implements, and supports endpoint security solutions for mission-critical networks supporting the NGA. Responsibilities include managing Linux-based security tools, integrating enterprise security platforms, troubleshooting, incident response, security event analysis, mitigation leadership, and compliance with DoD cybersecurity frameworks.