Top IT Jobs in St. Louis, MO

Provides hands-on IT and HRIS support for hardware, software, applications, servers, printers, and network systems. Responsibilities include troubleshooting technical issues, performing updates and backups, researching bugs and hosting options, supporting system conversions and recovery procedures, tracking service desk interactions, analyzing data integrity and system effectiveness, and assisting with application and infrastructure development. The intern also provides basic user support while meeting service desk performance standards.

Designs and operates cloud and internal infrastructure, identity and access management, SaaS platforms, and automation systems. The role improves reliability, security, compliance, and operational efficiency through IAM governance, infrastructure-as-code, CI/CD, vulnerability management, patching, system hardening, monitoring, and troubleshooting. It also partners with Security, HR, and Engineering on onboarding, integrations, and audit readiness.

Leads corporate and commercial IT business systems for a biopharmaceutical company, including ERP, P2P, HCM, CRM, data, BI, and AI capabilities. Owns technology roadmaps, implementations, budgets, vendor partnerships, and stakeholder relationships across Finance, HR, Legal, Compliance, and Commercial. Partners with the IT PMO to establish portfolio governance and reporting, supports R&D and GxP systems, and ensures CSV/CSA, security, privacy, and audit readiness.

Designs, implements, and maintains automated security detection, orchestration, and integration capabilities for USPS. Analyzes security telemetry, identifies anomalies and detection gaps, enhances detection content, validates workflows, and supports SOC, threat intelligence, and incident response teams. The role also translates operational needs into technical solutions, researches emerging security and machine-learning capabilities, and maintains documentation, runbooks, and procedures.

Manages Safety and Compliance Committee operations, including member rosters, appointments, onboarding, training records, conflict-of-interest logs, SME coordination, SOP implementation, reporting, and meeting support. The role maintains accurate governance documentation, coordinates with HRSA, OPTN contractors, internal teams, and committee members, and ensures compliance with oversight requirements and established operational plans.

Provides administrative and logistical support for Safety and Compliance Committees. Coordinates virtual meetings, agendas, presentations, minutes, transcriptions, recordings, and public summaries. Maintains committee rosters, records, procedures, dashboards, trackers, manuals, and reports while monitoring milestones and deliverables. Responds to stakeholder information requests and communicates committee activities to HRSA, OPTN leadership, committee members, contractors, and government entities. The role requires strong organization, documentation, communication, and records-management skills.

Provides primary application support for Epic systems, coordinating project-related issues and serving as a knowledgeable resource on organizational policies, procedures, and business operations. Maintains current Epic certifications, completes required new version training and recertification, and supports application areas according to Information Technology Analyst Ladder standards.

Provides primary application support for Epic referrals systems, coordinates application-related issues, and applies organizational policies, procedures, and business operations knowledge. Requires maintaining relevant Epic certifications, completing new version training and recertification, and supporting healthcare IT applications.

Administer Jira, Jira Service Management, Confluence, Loom, and Workato support platforms. Manage provisioning, permissions, workflows, custom fields, SLAs, automation, request queues, and access reviews. Monitor and troubleshoot Workato recipes, support citizen developers, automate repetitive administration, document configurations, and report on platform health. Complete moderately complex improvements independently while enforcing RBAC, least privilege, data privacy, and auditable processes.

The Senior IT QA Engineer owns quality strategy and outcomes across complex technology initiatives. Responsibilities include designing automated testing solutions, integrating quality verification into CI/CD pipelines, analyzing quality and production data, developing dashboards, managing risk, leading root-cause analysis, and influencing product, engineering, architecture, security, operations, and business stakeholders. The role requires technical contributions across web, mobile, API, data, cloud, and distributed systems, plus mentoring engineers and advancing quality engineering practices.

Administer enterprise SharePoint Server and SharePoint Online environments, including configuration, permissions, governance, monitoring, migrations, backup and recovery, security, compliance, and troubleshooting. Automate administrative tasks with PowerShell and support integrations with Microsoft 365, Power Apps, and Power Automate. Maintain infrastructure involving Active Directory, IIS, SQL Server, and network load balancing. Document procedures, enforce change management, communicate technical concepts, and mentor junior staff.

Designs, deploys, and administers Axonius integrations across enterprise IT and cybersecurity data sources. Develops queries, dashboards, enforcement actions, ingestion standards, quality checks, access controls, and governance policies. Supports systems engineering lifecycle activities, technical documentation, architecture reviews, Agile delivery, and operational transition. Integrates endpoint, cloud, identity, vulnerability management, CMDB, and network security platforms in a regulated enterprise environment.

Administers and governs enterprise Microsoft Power Platform environments across development, test, and production. Manages security, DLP policies, Dataverse, capacity, licensing, connectors, gateways, ALM, deployment pipelines, monitoring, and CoE operations. Develops governance standards, documentation, and reporting while troubleshooting platform issues and supporting compliance and change management. Collaborates with developers, architects, security teams, and business stakeholders, communicates technical concepts, and mentors junior staff.

Develop and maintain secure, scalable SharePoint Online solutions using SPFx, TypeScript, React, JavaScript, and Microsoft 365 integrations. Build reusable web parts and extensions, modernize legacy solutions, support migrations, troubleshoot performance and integration issues, manage testing and deployments, and document technical solutions. Collaborate with architects, administrators, developers, security teams, analysts, and stakeholders to translate business requirements into maintainable applications. Provide technical support and knowledge transfer while following accessibility, security, ALM, and development best practices.

Leads a Unix and Linux infrastructure team responsible for service delivery, operations, maintenance, incident resolution, and strategic project execution. Oversees technical strategy, modernization, automation, Agile delivery, ITIL practices, stakeholder communications, and continuous improvement. Manages recruitment, performance, training, mentoring, and professional development while guiding teams through complex technical and operational challenges. The role requires obtaining and maintaining a Public Trust and completing onsite fingerprinting.

Develops and maintains enterprise Power BI solutions, including dashboards, reports, semantic models, data transformations, SQL queries, row-level security, refreshes, gateways, and deployments. Translates business requirements into scalable analytics solutions, optimizes performance, troubleshoots data and connectivity issues, supports testing and documentation, and communicates findings to technical and non-technical stakeholders. Provides guidance to junior staff while collaborating across business, data, development, and architecture teams.

Leads IT GxP and SOX compliance, FDA inspection readiness, audit response, remediation, and evidence management. Owns the IT technology portfolio, including prioritization, roadmap governance, dependencies, reporting, and launch-readiness programs. Coordinates IT governance, procurement, budgeting, policies, SOPs, steering cadences, and cross-functional delivery. Partners with quality, finance, legal, vendors, and managed-service teams to maintain compliant, inspection-ready IT operations across biotech systems.

Drive business growth across North American IT and SAP accounts. Manage client relationships, identify new and expansion opportunities, lead sales pitches, proposals, contract negotiations, and SOW execution. Coordinate offshore delivery alignment, engage executive stakeholders, and manage sales pipelines, account roadmaps, and revenue metrics. The role operates remotely from India during North American night-shift hours and requires strong IT services, SAP, and enterprise client experience.

Manage the company’s IT department and ensure reliable operation of networks, servers, systems, security, and end-user technology. Responsibilities include AWS and Oracle administration, Microsoft 365 access management, technical support, cybersecurity monitoring, compliance, vendor coordination, budgeting, and leading IT infrastructure projects. The role also supports Windows and Apple devices, manages IT tickets, and coordinates cross-functional technology initiatives.

Lead cybersecurity consulting and engineering engagements securing OT and IT environments for water, wastewater, and environmental infrastructure clients. Conduct ICS, SCADA, network, architecture, risk, and compliance assessments; design secure IT/OT architectures; develop governance, incident response, security plans, and improvement roadmaps; evaluate security technologies; and support proposals and client presentations. Mentor junior staff and advise on cloud, IoT, AI, and critical infrastructure security.

Supports and improves IT infrastructure across multi-site healthcare centers, including endpoints, networks, cloud systems, printing, AV, phones, digital signage, SaaS applications, Microsoft 365, and Entra ID. Delivers site and technology projects, automates onboarding and offboarding, troubleshoots escalated issues, manages vendors, supports disaster recovery testing, and maintains documentation, security, asset inventories, and HIPAA-compliant access practices.

Record a genuine mistake and its recovery in one unbroken video, keeping hands visible and verbally explaining what happened. Upload the clip through the Kled app for review. Accepted submissions earn $3 each, with no interview or minimum hours. The task is remote, worldwide, self-scheduled, and performed as independent piecework using an iPhone running iOS 18.6 or later.

Record everyday tasks while continuously narrating actions with hands visible. Submit unbroken three- to five-minute clips through the Kled app for review and payment. Work remotely worldwide on a flexible, independent-contractor, piecework basis. Accepted clips pay $2.60 each, with typical earnings of approximately $22 per hour.

Develop and improve core software services supporting customer intake, application screening, and information dissemination. Design distributed, cloud-based, microservice architectures; identify bottlenecks; improve reliability and scalability; and deliver production-ready features. Work across the technology stack, contribute to system design and modernization, mentor junior developers, communicate technical decisions, and use data, AI, and automation to improve engineering outcomes.

Performs hands-on cybersecurity and AI engineering, defines and documents functional and technical requirements, converts requirements into Jira stories, validates application features, and collaborates with customers, developers, systems engineers, and AI stakeholders. Evaluates AI architectures, model performance, integration tradeoffs, and emerging AI/ML applications for enterprise software. Requires active TS/SCI with polygraph clearance, U.S. citizenship, a bachelor’s degree, and 15+ years of experience.