Top IT Jobs in San Diego, CA

Support and enforce NIST/CMMC-aligned security controls; monitor SIEM/EDR and perform incident triage and response; manage Windows/AD environments; conduct vulnerability scanning and remediation; protect and classify FCI/CUI; support audits and control validation; maintain compliance documentation; collaborate with IT and business teams and communicate security risks to technical and non-technical stakeholders.

Provide computer system validation and assurance support for cGMP-regulated systems. Create, review, execute, and document validation deliverables (IQ/OQ/PQ), coordinate revalidation, assess periodic reviews, and liaise with QA, IT, Engineering and business stakeholders to ensure compliance with GAMP, cGMP, 21 CFR Part 11, EU Annex 11 and ISO standards.

The Director of IT Operations leads the IT infrastructure, ensuring reliability, security, scalability, and efficiency while supporting business growth and managing the IT Operations team.

The role involves leading business development for IT solutions in federal contracting, leveraging relationships to identify opportunities and influence procurement strategies, while collaborating with various teams to drive success.

The IT Specialist will install, configure, and maintain IT systems, troubleshoot issues, perform hardware upgrades, and optimize network performance.

Provide IT support, manage website content, and collaborate on design improvements while ensuring data security and employee training.

The role involves managing enterprise systems, providing operational support, troubleshooting, designing user-centric solutions, and ensuring excellent customer service.

The IT Applications Lead manages the production support and implementation of Manufacturing and Quality applications in Oracle E-Business Suite, overseeing incident management, supporting users, and leading enhancements and projects.

The Manager of IT Engineering leads IT operations including identity management, SaaS, endpoint management, and internal tooling. This role ensures service quality and scalability for a remote workforce.

Provide 2nd/3rd shift IT support for a remote workforce, focusing on macOS and Apple device troubleshooting, Google Workspace and Okta administration, MDM and asset management, ticketing, documentation, AI-enabled workflow automation, and collaboration with IT/security for endpoint hygiene and incident escalation.

Provide hands-on end-user IT support: troubleshoot OS/software, respond to tickets, apply patches, manage user accounts via Okta, configure MDM-managed mobile devices, and support Slack and Google Workspace integrations.

Lead IT procurement and contracting for Digital Services: run RFx/RFPs, draft and negotiate contracts, manage renewals, oversee software licensing and vendor relationships, maintain procurement records, resolve disputes, and mentor junior staff.

Support the Risk Mitigation team by managing vulnerability scanning, assessment, tracking, and remediation. Collaborate with security and IT teams to research vulnerabilities, enforce risk-based remediation, automate reporting, maintain documentation, and ensure compliance with standards like PCI-DSS, SOC 2, NIST, and CIS. Perform recurring and on-demand scans across systems and cloud environments and assist with incident or zero-day vulnerability resolution.

Manage internal IT infrastructure and developer operations while leading frontend web work. Run developer standups, own sprint planning in ClickUp, triage requests, perform hands-on frontend fixes (HTML/CSS/JS), manage AWS resources, administer Google Workspace and Okta SSO, oversee VPN and endpoint security, and coordinate QA and deployments across web properties.

Lead global strategic sourcing for IT & automation categories ($450M+ spend). Develop category strategies, drive multi-million dollar savings, lead supplier relationship and risk management, conduct tenders and contract negotiations (> $500K), mentor sourcing managers, align senior stakeholders, implement supplier performance KPIs and innovation, and support cross-functional procurement initiatives. Expect ~20% travel.

The IT Communications Officer manages all IT networks and systems on board luxury cruise ships, providing technical support, user management, and ensuring communication infrastructure is operational.

Develop and maintain Digital Workplace tools, working closely with teams, performing testing, debugging, and technical research. Requires web development experience and familiarity with modern software architectures.

The IT Project Manager will oversee project planning, implementation, and client interactions while ensuring compliance with federal and state regulations in the public sector.

The IT Project Manager will lead public sector ERP migration projects, ensuring high-quality deliverables and strategic alignment while collaborating with various stakeholders.

The IT Applications Business Analyst supports Oracle EBS, translating business needs into solution designs, improving processes, and resolving application issues across various operational sectors.

Build end-to-end automation and AI agents across identity, endpoint, SaaS, and ITSM systems. Automate onboarding/offboarding, ticket triage, self-service flows, and integrations. Operate and govern Vertex AI agents, establish KPIs, mentor sysadmins, and maintain reliable, auditable automations with security and compliance controls.

As an IT Operations Engineer, you will manage IT operations across multiple companies, handling identity management, SaaS platforms, and automations to optimize processes and support users effectively.

The Senior IT Project Manager oversees the delivery of technology and business transformation projects, supports PMO standards, manages project risks, and mentors junior managers.

The IT Systems Engineer will manage IT operations, support M&A integrations, and optimize Microsoft cloud systems, ensuring reliability and security.

The Manager of Internal Audit (IT) leads audit engagements, supervises staff, and develops risk-based audit schedules while ensuring compliance with regulatory standards.