Top Senior IT Jobs in San Diego, CA

Lead end-to-end IT sourcing for hardware, software, SaaS, and security services. Develop sourcing strategies, run RFx and negotiations, draft and manage contracts, perform market and TCO analysis, mitigate risks, manage supplier performance, and align cross-functional stakeholders to optimize cost, performance, and vendor portfolios.

The Senior Internal Auditor II - IT evaluates internal controls, supports SOX compliance, collaborates with stakeholders, and provides IT advisory services.

Designs and leads OneTrust Consent Management and Data Discovery architectures for life sciences clients. Integrates OneTrust with Salesforce, Veeva, Databricks, Snowflake, Azure, and AWS; creates ERDs, data dictionaries, and data flow diagrams; translates privacy requirements into technical designs; leads configuration with admins and developers; collaborates with legal, compliance, IT, and delivery teams; supports pre-sales workshops and client engagements. Requires approximately 10–20% travel.

Serve as a functional Commercial CRM Business Analyst for life-sciences CRM implementations. Lead discovery, gather requirements, create user stories and process maps, author UAT/test scripts, support pre-sales scoping, and liaise between business stakeholders, solution architects, and developers to ensure commercial workflows and Agentforce use cases are implemented effectively.

Deploy and maintain AI enablement infrastructure (MCP servers, AI agents, AI features in SaaS), manage service accounts and API keys, automate and containerize services, support enterprise IT systems, document integrations and runbooks, and mentor IT support staff.

Owns the company-wide IT and cybersecurity program, including SOC 2 compliance, cloud security, penetration-test remediation, business continuity testing, endpoint management, access controls, onboarding and offboarding, AI security governance, vendor reviews, security training, incident response, and employee IT support. The role partners with engineering, HR, Finance, leadership, auditors, and healthcare customers while managing security across AWS, Heroku, Cloudflare, Google Workspace, GitHub, and related tools.

Lead end-to-end technology integration for client mergers/acquisitions into Hardware Engineering Compute. Manage stakeholders, steering committees, budgets, change management, communications, scope, and delivery across multiple workstreams.

Provide functional leadership and support for Oracle Cloud Financials Procure-to-Pay (P2P) processes. Configure and deliver full lifecycle implementations and post-production managed services, troubleshoot production issues, gather and document requirements, design scalable configurations, lead enhancements, and advise clients on controls, workflows, integrations, and reporting to optimize P2P operations.

Lead billing operations for recurring, project, and hardware-as-a-service revenue in a $100M+ MSP. Ensure invoice accuracy, ASC 606 alignment, month-end cutoffs, and cross-team validation. Drive automation, system integrations (PSA/CRM/ERP), process documentation, audit support, and manage a small team of billing specialists to improve scalability and collections.

Manage multiple public-sector IT infrastructure projects end-to-end, ensuring on-time, on-budget delivery. Lead stakeholders, vendors, and internal teams; build schedules, manage risks, finances, QA, and client communications for networking, wireless, and unified communications engagements.

Provide functional support, optimization, issue resolution, and enhancements for Oracle Cloud Financials (primarily General Ledger). Engage with clients to gather requirements, design and configure solutions, lead implementations and post-production managed services, troubleshoot issues, and improve financial processes and reporting across financial modules.

Lead assessment and remediation of IT security risks across network, systems, and applications. Perform vulnerability assessments, manage IDS/IPS, coordinate remediation with IT and vendors, develop policies and training, support audits (SOX/PCI/HIPAA), and report findings to stakeholders while mentoring teams and guiding security projects.

Lead Fabric's security program and corporate IT operations, including identity, endpoint, cloud, application, and vendor security. Hire and manage a small team, run incident response, handle customer security questionnaires, partner on SOC2/HITRUST/HIPAA control implementation, and set practical security policy while remaining hands-on in operations and tooling.

Own and operate the organisation's accounts, access, and cloud subscriptions; set practical security standards; identify and remediate risks hands-on; manage onboarding/offboarding access across core platforms; partner with engineers and researchers to ensure secure, usable controls.

Lead end-to-end IT risk-based audits, test ITGCs and key IT risks, manage continuous audit testing, support external audits, advise on new technologies (cloud, AI, cybersecurity), communicate findings to leadership, and lead team development and advisory projects across the enterprise.

Develop, implement, and maintain security policies and controls mapped to NIST CSF; manage policy and compliance workflows in ServiceNow IRM; perform risk assessments and gap analyses; support audit readiness and vendor assessments; produce dashboards and reports; lead security awareness and AI governance training; mentor junior analysts; collaborate with IT, risk, compliance, and business teams to drive remediation and policy adoption.

Lead enterprise cybersecurity and IT operations for a HIPAA-regulated healthcare company: build and mature security programs, manage IAM/endpoint/cloud security, drive vulnerability management and incident response, ensure compliance (HIPAA/HITECH), oversee IT operations and vendor risk, and mentor a technical team while partnering with cross-functional leadership.

Manage and execute RCA's cybersecurity program: lead audits and vendor risk assessments, run security awareness/phishing programs, oversee vulnerability remediation and MDM, ensure HIPAA/HITECH/NIST compliance, build security reporting, and coordinate incident response and tabletop exercises.

Build and lead a centralized IT function across a holding company and portfolio. Run acquisition IT workstreams and create a Day 1-100 integration playbook. Select and operate identity and access systems, build joiner/mover/leaver processes, maintain living inventory of tools/accounts/licenses, manage MSP relationships and vendor contracts, and connect back-end systems to the cross-portfolio data platform while engaging business stakeholders.

Own and scale corporate IT systems including Windows/macOS endpoints, MDM, identity (Okta, Google Workspace), SaaS administration, automation (PowerShell/Bash/Python/APIs), onboarding/offboarding, endpoint security, and audit readiness. Troubleshoot complex issues, build runbooks, and partner with Security, Engineering, People, and Operations to operationalize repeatable, compliant IT processes.

Lead enterprise IT audit strategy and execution for insurance and financial systems. Oversee audits of core insurance platforms, financial systems, cybersecurity, cloud, IAM, SDLC, and regulatory compliance. Advise executives and regulators, manage remediation, prepare Audit Committee reporting, and mentor IT audit staff.

Senior IT leader responsible for leading a 30+ developer application development organization across multiple insurance lines. Owns modernization, legacy reduction, AI-enabled application delivery, cloud architecture, vendor evaluations, and roadmap alignment with business stakeholders while developing engineering managers and driving cross-line transformation.

Lead commercial strategy and execution for IT spend categories (SaaS, cloud, endpoint, telecom). Manage renewals, run competitive sourcing events, negotiate pricing and contract terms, build TCO and spend analysis, coordinate legal and security reviews, maintain vendor frameworks, and align cross-functional stakeholders to deliver savings and reduce vendor risk.

Perform end-to-end FedRAMP assessments for cloud service providers: interview SMEs, review IaaS architectures (AWS/Azure/OCI), validate NIST SP 800-53 controls, analyze vulnerabilities, verify encryption and configurations, draft deliverables, and mentor project team members.

Perform end-to-end FedRAMP assessments: interview CSP SMEs, walkthrough cloud architectures (AWS/Azure/OCI), evaluate NIST SP 800-53 controls, validate configurations and vulnerabilities, draft deliverables, train and mentor team members, and support practice development.