Top Senior Python Jobs in San Diego, CA

As a Solution Architect Senior Manager, you will lead software solution development, drive digital transformation, and oversee teams through complex projects while maintaining client relationships.

Lead teams to deliver AWS-based solution architecture, manage cloud migration initiatives, and innovate processes while engaging senior clients. Foster team growth and operational excellence.

Lead full stack application migrations to AWS, architect solutions, mentor teams, and drive AI-native engineering strategy while ensuring cloud readiness and modernization.

Lead the design and implementation of Azure platform solutions, mentor junior staff, and ensure successful project delivery while maintaining high standards.

The Manager, Solution Architect at PwC leads digital integration projects, focusing on cloud migration, AI-native development, and mentoring engineering teams while ensuring quality deliverables and strategic architecture design.

The Lead Software Engineer will design, implement, and test software for advanced data communications and networking solutions, mentor junior engineers, and lead technical discussions in a fast-paced environment.

Design and develop scalable software components, mentor junior engineers, collaborate with product teams, and integrate AI in workflows.

Design and develop scalable software components with a focus on performance. Collaborate with teams to create user experiences, integrate testing, and enhance product capabilities.

Lead software development and innovation efforts, mentor teams, manage projects and client relationships, and implement software solutions that drive digital transformation.

The Senior Software Engineer will design and implement software solutions for advanced algorithmic applications, enhancing software architecture and collaborating with different teams and customers to meet national security needs.

Lead frontend engineering within AI Agents team, focusing on architecture standards, UI component libraries, backend services, and collaboration with UX teams. Drive innovation and integrate AI solutions.

Drive SoC and server platform performance by characterizing real-world AI/HPC workloads on production silicon, designing microbenchmarks, diagnosing bottlenecks, and translating findings into architectural and system-level optimizations while collaborating with hardware and software teams.

Vannevar is seeking a Senior Software Engineer to lead the deployment of AI-enabled software products in government environments, focusing on security and compliance. Responsibilities include roadmap ownership, technical design, mentorship, and documentation.

Senior individual contributor owning Axos Banks Azure platform, identity governance, security posture, cost management, and automation. Design, deploy, and maintain Azure infrastructure and Entra ID; drive security remediation, compliance reporting, cost optimization, and ServiceNow-based change management. Act as technical peer for architecture, support hybrid identity, and enable audited operational discipline for a federally regulated financial institution.

Owner of the cloud platform for a vision-based Physical AI product: design and build cloud ingestion, storage, platform APIs, multi-tenant access control, identity/SSO, agent orchestration, and infrastructure/DevOps using managed services where appropriate.

Lead thermomechanical simulation for ASIC packages and board assemblies using advanced FEA to assess stress, warpage, and interconnect reliability. Own solder joint reliability assessments, model nonlinear/time-dependent material behavior, define simulation methodologies, correlate simulation with test data, drive design decisions, automate workflows (Python/Fortran), and lead cross-functional root-cause analysis.

Lead thermomechanical FEA for ASIC packages and board assemblies, model solder joint reliability and time-dependent material behavior, drive board-level reliability assessments, correlate simulations with test data, automate workflows, and provide design recommendations and reliability sign-off to cross-functional teams.

Design, build and operate secure, scalable public cloud platform capabilities across Azure and GCP using Infrastructure as Code, CI/CD, Kubernetes and service mesh. Implement observability, SLOs/SLIs, API-first delivery and security-by-design, mentor engineers, and evolve platform strategy to enable developer self-service.

Lead development and implementation of automated test strategies, frameworks, and test environments for the eLxr Linux distribution. Design, integrate, and verify tests for safety-critical embedded and enterprise systems, mentor engineers, improve tooling and workflows, and collaborate with product and global engineering teams to deliver scalable, high-quality solutions.

The AI Architect II leads the modernization of the company’s technology platform by establishing AI architectural standards, integrating AI services, overseeing MLOps practices, and collaborating with stakeholders to design scalable cloud architectures and AI solutions.

The role involves designing, developing, and supporting software for complex electro-mechanical systems in semiconductor manufacturing. Responsibilities include full lifecycle development, troubleshooting, and collaboration across teams.

Manage and automate enterprise Linux/Unix platforms across on-prem and hybrid VMware environments. Ensure availability, security compliance (SOX/FFIEC), perform patching, tuning, incident (P1/P2) response and RCA. Build Puppet modules for provisioning and drift remediation, script with Bash/Python, support backup/DR (Zerto), and execute changes via ServiceNow while maintaining runbooks and audit-ready documentation.

The Staff Software Engineer leads architecture and performance improvements for core robotics software, focusing on HAL, middleware, and sensor integration. Responsibilities include design, optimization, cross-functional collaboration, and technical mentorship.

As a Senior Autonomy Engineer, you'll develop machine learning systems for robot navigation, improve learned components, manage features end-to-end, and mentor team members.

The Senior Systems Engineer is responsible for the design, implementation, and maintenance of core infrastructure systems, including virtualization, storage, networking, and security, while driving automation and operational reliability.