Top Senior Python Jobs in San Diego, CA

4 Days AgoSaved
Hybrid
San Diego, CA
130K-222K Annually
Senior level
130K-222K Annually
Senior level
Aerospace • Hardware • Information Technology • Security • Software • Cybersecurity • Defense
Leads FPGA design verification for electronic warfare systems by architecting SystemVerilog/UVM or VHDL testbenches, developing constrained-random test plans, analyzing coverage, creating reusable verification IP, and improving methodologies. The role includes leading verification teams, mentoring engineers, managing schedules, supporting multiple projects, and collaborating across locations. Candidates need extensive FPGA/ASIC verification experience, relevant tools expertise, strong communication skills, and a current Secret clearance or eligibility to obtain one.
Top Skills: AsicBitbucketC++CadenceDigital Signal ProcessingFpgaGitJavaJIRAMatlabMentor QuestaOvmPerlPythonSimulinkSystemverilogUvmVhdl
4 Days AgoSaved
Hybrid
San Diego, CA
Senior level
Senior level
Artificial Intelligence • Internet of Things • Semiconductor
Leads SoC power analysis, modeling, optimization, and pre- and post-silicon power convergence. Manages and mentors power engineers while collaborating with architecture, design, verification, and product teams. Defines power methodologies, workflows, budgets, and sign-off processes; develops workload scenarios; improves accuracy and silicon correlation; and drives performance-per-watt targets throughout the SoC lifecycle.
Top Skills: AsicEda ToolsEmulationIncisiveNetlistPalladiumPythonQuestasimRtlSimulationSocVcsVeloce StratoZebu
4 Days AgoSaved
Remote or Hybrid
San Diego, CA
172K-301K Annually
Senior level
172K-301K Annually
Senior level
Artificial Intelligence • Cloud • HR Tech • Information Technology • Productivity • Software • Automation
Lead architecture and technical direction for a high-volume log analytics platform spanning ingestion, storage, querying, reliability, and AI-driven capabilities. Shape the roadmap with engineering, product, leadership, and customers; build prototypes; guide migrations and schema changes; set reliability and cost standards; influence teams without direct ownership; mentor senior engineers and technical leads; and promote strong practices in quality, on-call operations, and incident learning.
Top Skills: AIAmazon KinesisApache PulsarCloud InfrastructureColumnar DatabasesElasticsearchGoJavaKafkaKubernetesLlmsObject StorageOpensearchOpentelemetryPythonRustScalaTime-Series Databases
4 Days AgoSaved
Hybrid
San Diego, CA
99K-232K Annually
Senior level
99K-232K Annually
Senior level
Artificial Intelligence • Professional Services • Business Intelligence • Consulting • Cybersecurity • Generative AI
Leads the development and deployment of data solutions using Palantir Foundry and AIP. Manages engineering teams, coaches team members, oversees project planning and execution, analyzes system interactions, manages client relationships, and drives innovation. The role applies software engineering, data engineering, analytics, and AI/ML techniques to deliver scalable client solutions while maintaining technical and professional standards.
Top Skills: Artificial IntelligenceMachine LearningPalantir AipPalantir FoundryPythonTypescript
4 Days AgoSaved
Hybrid
San Diego, CA
77K-202K Annually
Senior level
77K-202K Annually
Senior level
Artificial Intelligence • Professional Services • Business Intelligence • Consulting • Cybersecurity • Generative AI
Leads the development and deployment of software and data solutions using Palantir Foundry and AI/ML technologies. Responsibilities include data engineering, analytics, system improvement, client account management, project ownership, team leadership, coaching, stakeholder engagement, and continuous improvement. The role requires building scalable applications with large datasets and delivering customer-focused solutions.
Top Skills: Artificial IntelligenceData AnalyticsData EngineeringMachine LearningPalantir AipPalantir FoundryPythonTypescript
6 Days AgoSaved
Remote or Hybrid
San Diego, CA
172K-301K Annually
Senior level
172K-301K Annually
Senior level
Artificial Intelligence • Cloud • HR Tech • Information Technology • Productivity • Software • Automation
Leads the most complex AI deployments, escalations, and go-live support engagements. Sets the strategic roadmap for program tooling and infrastructure, evolves quality standards and playbooks, drives systemic improvements, mentors engineers, and partners with product, engineering, and customer success leadership. Represents the program in executive customer discussions while deploying and integrating AI features across enterprise environments.
Top Skills: Ai AgentsGenerative AiJavaJavaScriptNow AssistPrompt EngineeringPython
6 Days AgoSaved
Hybrid
San Diego, CA
157K-197K Annually
Senior level
157K-197K Annually
Senior level
Aerospace • Artificial Intelligence • Cloud • Machine Learning • Software • Cybersecurity • Defense
Lead digital and embedded engineering for aerospace radar and electronic warfare products. Architect, design, simulate, verify, integrate, and transition digital subsystems and circuit cards into production. Develop FPGA architectures and VHDL firmware, create DSP algorithms, oversee circuit card design, and interface with RF and motion-control systems. Lead testing, documentation, customer collaboration, and technical mentorship of junior engineers.
Top Skills: AdcsAltera Platform DesignerAltera QuartusCC++DacsDigital Signal ProcessingDramElectronic WarfareEthernetFpgaI2CJesd204LuaMatlabMicrocontrollersPci ExpressPythonRadarRf SystemsSimulinkSpiTclVhdlXilinx System GeneratorXilinx Vivado
10 Days AgoSaved
Hybrid
San Diego, CA
97K-165K Annually
Senior level
97K-165K Annually
Senior level
Aerospace • Hardware • Information Technology • Security • Software • Cybersecurity • Defense
Develop and use configurable, self-checking FPGA verification environments using SystemVerilog/UVM and/or VHDL. Create constrained-random test plans, reusable Verification IP, and coverage-driven test cases for electronic warfare signal-processing and control systems. Analyze metrics, improve verification methodologies, execute tasks across multiple projects, and collaborate with engineers and subject matter experts across U.S. locations.
Top Skills: AsicBitbucketC++CadenceDigital Signal ProcessingFpgaGitJavaJIRAMatlabMentor QuestaOvmPerlPythonSimulinkSystemverilogUvmVhdl
12 Days AgoSaved
Hybrid
San Diego, CA
133K-226K Annually
Senior level
133K-226K Annually
Senior level
Aerospace • Hardware • Information Technology • Security • Software • Cybersecurity • Defense
Designs and maintains secure on-premises and cloud infrastructure, CI/CD pipelines, automation, container platforms, monitoring, and deployment processes. Troubleshoots infrastructure, networking, and production incidents while improving system reliability, scalability, and security. Collaborates with development teams, customers, and external stakeholders in a hybrid environment. The role requires active Secret clearance and experience with AWS GovCloud, air-gapped environments, virtualization, Linux administration, Kubernetes, Docker, scripting, automation, and infrastructure integration.
Top Skills: AnsibleAws GovcloudBashChefCi/CdCloud InfrastructureContainer OrchestrationContainerizationDockerDocker SwarmElk StackGitlabKubernetesLinuxNagiosPowershellPrometheusPuppetPythonRancherUnixVirtualization
16 Days AgoSaved
In-Office
San Diego, CA
128K-192K Annually
Senior level
128K-192K Annually
Senior level
Aerospace • Artificial Intelligence • Machine Learning • Robotics • Software • Defense Technology
Integrate, validate, and deploy autonomy software across simulations, hardware-in-the-loop environments, and flight platforms. Configure sensors, interfaces, and platform adapters; develop integration tooling, deployment scripts, and configuration management; troubleshoot system behavior using logs, telemetry, and rosbag data; optimize CI/CD workflows; validate requirements and interface contracts; and collaborate with engineering, product, DevOps, and customer teams to deliver reliable autonomous systems.
Top Skills: Autonomous SystemsC++Ci/CdCommunication InterfacesEmbedded SystemsHardware-In-The-Loop (Hil)MiddlewareNetworkingOperating SystemsPythonRadio CommunicationsRoboticsRosRosbagSensor DriversSimulation ToolsSoftware-In-The-Loop (Sil)
16 Days AgoSaved
In-Office
San Diego, CA
130K-240K Annually
Senior level
130K-240K Annually
Senior level
Aerospace • Artificial Intelligence • Machine Learning • Robotics • Software • Defense Technology
Build and support full-stack applications for developing, training, simulating, and evaluating autonomous systems. Develop React and TypeScript interfaces, backend services, APIs, data models, and Python workflows. Deploy and troubleshoot containerized services across local, cloud, on-premises, and air-gapped Kubernetes environments. Collaborate with users, product, design, and engineering teams to translate complex workflows into reliable, extensible applications and reusable platform capabilities.
Top Skills: Argo WorkflowsCi/CdDagsterDockerGoGrpcHelmJson SchemaKubernetesOpenapiProtocol BuffersPythonRayReactTypescriptWebsockets
17 Days AgoSaved
In-Office
San Diego, CA
260K-390K Annually
Senior level
260K-390K Annually
Senior level
Aerospace • Artificial Intelligence • Machine Learning • Robotics • Software • Defense Technology
Leads the technical vision, architecture, and development of Guidance, Navigation, Control, and State Estimation capabilities for autonomous aircraft. Builds and mentors a specialist engineering team, develops production autopilot and flight-control software, establishes reusable GNC platforms, and drives simulation, hardware-in-the-loop, and flight testing. Partners on Runtime Assurance, safety, airworthiness evidence, customer integrations, and cross-organization technical roadmaps.
Top Skills: Automated TestingC++Continuous IntegrationHardware-In-The-Loop TestingMatlabMonte Carlo AnalysisPythonRuntime AssuranceSimulinkSoftware-In-The-Loop TestingVersion Control
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17 Days AgoSaved
In-Office
San Diego, CA
130K-240K Annually
Senior level
130K-240K Annually
Senior level
Aerospace • Artificial Intelligence • Machine Learning • Robotics • Software • Defense Technology
Build and support production full-stack applications with a frontend focus using TypeScript and React. Design intuitive interfaces for simulation, synthetic data, testing, evaluation, and autonomy workflows. Integrate APIs and backend services, improve performance and accessibility, test complete user workflows, and create reusable components and extension points. Collaborate closely with developers, product, design, and domain experts to deliver reliable applications across local, cluster, edge, and air-gapped environments.
Top Skills: DdsGoGrpcJson SchemaMavlinkMicro-FrontendsModel Context ProtocolMqttOpenapiProtocol BuffersPythonReactRestTypescriptVs Code ExtensionsWeb ComponentsWebsockets
17 Days AgoSaved
In-Office
San Diego, CA
110K-210K Annually
Senior level
110K-210K Annually
Senior level
Aerospace • Artificial Intelligence • Machine Learning • Robotics • Software • Defense Technology
Conduct structural analysis and testing for advanced UAV airframes and components. Build finite element models, perform static, modal, fatigue, and vibration analyses, validate results with hand calculations, define load cases and design margins, analyze telemetry and test data, and collaborate with multidisciplinary engineering teams to optimize lightweight structures for strength, safety, weight, and manufacturability.
Top Skills: AnsysCatiaComposite MaterialsExcelFemapFinite Element Analysis (Fea)HyperworksMatlabMetallic MaterialsNastranNxPatranPythonSolidworksTeamcenter
23 Days AgoSaved
In-Office
San Diego, CA
230K-350K Annually
Senior level
230K-350K Annually
Senior level
Aerospace • Artificial Intelligence • Machine Learning • Robotics • Software • Defense Technology
Lead integration of autonomy components into reference implementations and deployable stacks. Develop C++ and Python tooling, software-in-the-loop and hardware-in-the-loop tests, platform integration layers, automated fixtures, and troubleshooting workflows. Investigate cross-system failures, support deployment to representative hardware, collaborate on flight testing, analyze integration issues, and create documentation and training materials. The role spans perception, localization, planning, real-time systems, and safety-critical autonomous platforms.
Top Skills: Artificial IntelligenceAutonomous SystemsC++ConanDistributed SystemsHardware-In-The-LoopLinuxNixPythonRoboticsSoftware-In-The-LoopVlasVlms
23 Days AgoSaved
In-Office
San Diego, CA
160K-250K Annually
Senior level
160K-250K Annually
Senior level
Aerospace • Artificial Intelligence • Machine Learning • Robotics • Software • Defense Technology
Develop and maintain autonomy integration environments, reference configurations, automated software-in-the-loop and hardware-in-the-loop tests, integration tools, and vehicle or hardware interfaces. Debug failures across planning, controls, simulation, perception, deployment, network, timing, and hardware boundaries. Support autonomy stack deployment, lab and flight testing, failure analysis, documentation, and technical collaboration across multidisciplinary teams.
Top Skills: C++Hardware-In-The-Loop TestingLinuxMavlinkPythonRobotics MiddlewareSoftware-In-The-Loop Testing
21 Minutes AgoSaved
In-Office
San Diego, CA
260K-320K Annually
Senior level
260K-320K Annually
Senior level
Artificial Intelligence • Robotics
Own the secure manufacturing pipeline for humanoid robots, including factory provisioning stations, device identity enrollment, firmware flashing, calibration, EOL testing, OTA readiness, and chain-of-custody tracking. Design secure hardware, software, and network infrastructure using PKI and AWS services. Develop production-grade Python or Bash automation, collaborate with firmware and cloud teams, threat-model contract manufacturing environments, and establish quality gates and secure processes for distributed manufacturers.
Top Skills: Aws CloudhsmAws EcsAws IamAws KmsAws Private CaAws S3Aws Secrets ManagerBashBazelEfuseEmbedded LinuxHsmMtlsNvidia Jetson OrinNvidia Jetson ThorPythonRustSecure BootSystemdTpmTrustzoneX.509
An Hour AgoSaved
In-Office
San Diego, CA
Senior level
Senior level
Consulting
Build, parameterize, validate, and port real-time plant models for HIL benches using MATLAB/Simulink and OPAL-RT. Configure I/O, signal routing, and fault-injection scenarios; tune models against reference data; support closed-loop integration; analyze results; and produce documentation, test evidence, and status updates. The role requires expertise in control systems, power electronics simulation, real-time modeling, OPAL-RT platforms, MATLAB/Simulink, Stateflow, and C/C++.
Top Skills: CC++DspaceEfpgasimFpgaHypersimMatlabOpal-RtPythonRt-LabSimulinkSpeedgoatStateflowTyphoon Hil
An Hour AgoSaved
In-Office
San Diego, CA
145K-170K Annually
Senior level
145K-170K Annually
Senior level
Fintech
Own and operate the Apigee X API gateway, including proxies, shared flows, security policies, environments, deployments, governance, CI/CD, monitoring, and incident response. Partner with infrastructure, network, security, and engineering teams to establish API standards and onboard users. Extend the gateway for LLM traffic and MCP integrations with provider abstraction, authentication, rate limiting, logging, AI safety controls, and auditability in a regulated banking environment.
Top Skills: AnthropicApigee XAws BedrockCi/CdDnsGCPJavaJwtMcpModel ArmorMtlsNode.jsOauth 2.0OidcOpenaiPythonTerraformTlsVertex Ai
An Hour AgoSaved
In-Office
San Diego, CA
125K-175K Annually
Senior level
125K-175K Annually
Senior level
Hardware • Semiconductor • Quantum Computing • Manufacturing
Design and execute complex mechanical engineering tasks for optical alignment machines, including CAD design, quantitative analysis, fabrication, integration, testing, documentation, and data analysis. The role involves precision automation, large assemblies, structural and thermal analysis, materials and manufacturing methods, linear stages, instrumentation, and mentoring junior engineers in a startup environment.
Top Skills: 3D PrintingAnsys WorkbenchCnc MillingCnc TurningInjection MoldingInstrumentationLaser CuttingLinear RailsPrecision Linear StagesPythonRoboticsSheet Metal FabricationSolidworksWater Jet Cutting
An Hour AgoSaved
In-Office
San Diego, CA
175K-225K Annually
Senior level
175K-225K Annually
Senior level
Hardware • Semiconductor • Quantum Computing • Manufacturing
Designs, analyzes, documents, tests, and supports precision opto-mechanical assemblies, laser systems, and photonic products. Performs structural, thermal, vibration, fluid, and heat-transfer analysis; designs optical flexures and metrology setups; conducts experiments; supports fabrication, procurement, integration, and testing. The role requires extensive mechanical engineering expertise, CAD and quantitative analysis, technical documentation, independent execution, collaboration, and mentoring junior engineers in a startup environment.
Top Skills: 3D PrintingAnsys WorkbenchCnc MillingCnc TurningDie BondingFiber OpticsInjection MoldingLaser CuttingLaser SystemsMechanical CadOptical MetrologyPhotonicsPythonSheet Metal FabricationSolidworksStructural AnalysisThermal AnalysisVacuum Reflow SolderingVibration AnalysisWater Jet CuttingWire Bonding
An Hour AgoSaved
In-Office
San Diego, CA
125K-175K Annually
Senior level
125K-175K Annually
Senior level
Hardware • Semiconductor • Quantum Computing • Manufacturing
Performs complex mechanical engineering tasks involving design, analysis, fabrication, integration, testing, documentation, and data-driven decision-making. The role requires expertise in materials, mechanisms, fabrication methods, photonic assembly, structural mechanics, fluids, heat transfer, CAD, Python, and ANSYS Workbench. The engineer will work independently and collaboratively, mentor junior engineers, and help establish engineering practices in a fast-paced startup environment.
Top Skills: 3D PrintingAnsys WorkbenchCnc MillingCnc TurningDie BondingInjection MoldingInstrumentation And MeasurementLaser CuttingMechanical CadPythonSheet Metal FabricationSolidworksVacuum Reflow SolderingWater Jet CuttingWire Bonding
An Hour AgoSaved
In-Office
San Diego, CA
Senior level
Senior level
Artificial Intelligence • Hardware • Software • Defense • Manufacturing
Own and advance software verification for autonomous maritime vessels. Build unified testing infrastructure spanning Rust tests, VM integration, HITL stations, simulation, replay, fuzzing, fault injection, and CI orchestration. Develop reusable testing frameworks, investigate failures, improve reliability, and collaborate with autonomy, controls, networking, hardware, and infrastructure teams. The role requires strong systems engineering, debugging, and cross-functional collaboration, with occasional travel to operational test sites.
Top Skills: C++Can BusCi/CdDeterministic SimulationFuzz TestingHardware-In-The-Loop (Hitl)McapNixosProperty-Based TestingPythonReplay-Based TestingRustVm Integration Testing
An Hour AgoSaved
In-Office
San Diego, CA
98K-148K Annually
Senior level
98K-148K Annually
Senior level
Healthtech • Biotech
Leads system-level verification and validation for complex sequencing platforms from development through launch. Develops test strategies, plans, fixtures, instrumentation, and automated test infrastructure; evaluates performance, reliability, thermal control, and operating margins. Applies DOE, statistical analysis, troubleshooting, and root cause analysis to resolve issues. Partners with multidisciplinary engineering, quality, manufacturing, and operations teams, communicates technical risks and recommendations, drives continuous improvement, and mentors engineers.
Top Skills: Design ControlsDna Sequencing SystemsEngineering Data PlatformsJIRALabviewMatlabNext-Generation Sequencing (Ngs)PythonRequirements Management ToolsTec/Peltier Temperature ControlTest Management Systems
2 Hours AgoSaved
In-Office
San Diego, CA
104K-155K Annually
Senior level
104K-155K Annually
Senior level
Aerospace • Logistics • Security • Software • Cybersecurity
Manage software configuration processes, release schedules, builds, deployments, repositories, and configuration control boards for a DoD program. Coordinate with development, QA, administrators, and customers to resolve issues, maintain tools and documentation, support VHDL repositories, administer collaboration platforms, and troubleshoot system problems. The role requires strong communication, scripting, database, software build, and configuration management expertise, along with an active Secret clearance.
Top Skills: Adobe Acrobat ProBatchBitbucketDatabasesDesign SyncGitJIRAMicrosoft Office SuitePdmPerlPlmPythonRational ToolsetsScripting LanguagesSharepointStm ProVhdlVisioWindows
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