Top Senior Python Jobs in San Diego, CA

Reposted 3 Days AgoSaved
Hybrid
San Diego, CA
124K-280K Annually
Senior level
124K-280K Annually
Senior level
Artificial Intelligence • Professional Services • Business Intelligence • Consulting • Cybersecurity • Generative AI
Oversee software engineering projects, lead large-scale distributed data processing systems, mentor junior staff, and drive project success.
Top Skills: Apache NifiContainer Orchestration ToolsDatabase DesignEvent Driven DesignJava 8KafkaMicroservicesPythonRest Api
3 Days AgoSaved
Hybrid
San Diego, CA
124K-280K Annually
Senior level
124K-280K Annually
Senior level
Artificial Intelligence • Professional Services • Business Intelligence • Consulting • Cybersecurity • Generative AI
Lead teams to deliver AWS-based solution architecture, manage cloud migration initiatives, and innovate processes while engaging senior clients. Foster team growth and operational excellence.
Top Skills: ArgocdAWSCloudFormationFluxGithub ActionsGoKubernetesPythonTerraform
3 Days AgoSaved
Hybrid
San Diego, CA
99K-232K Annually
Senior level
99K-232K Annually
Senior level
Artificial Intelligence • Professional Services • Business Intelligence • Consulting • Cybersecurity • Generative AI
The role focuses on designing and delivering Azure-based cloud solutions, mentoring teams, and driving cloud migration initiatives to enhance client operations.
Top Skills: AksAzureGoInfrastructure As CodeKubernetesPython
3 Days AgoSaved
Hybrid
San Diego, CA
99K-232K Annually
Senior level
99K-232K Annually
Senior level
Artificial Intelligence • Professional Services • Business Intelligence • Consulting • Cybersecurity • Generative AI
Lead the design and implementation of Azure platform solutions, mentor junior staff, and ensure successful project delivery while maintaining high standards.
Top Skills: AzureGoKubernetesPythonTerraform
Reposted 3 Days AgoSaved
Hybrid
San Diego, CA
124K-280K Annually
Senior level
124K-280K Annually
Senior level
Artificial Intelligence • Professional Services • Business Intelligence • Consulting • Cybersecurity • Generative AI
Lead full stack application migrations to AWS, architect solutions, mentor teams, and drive AI-native engineering strategy while ensuring cloud readiness and modernization.
Top Skills: Ai Coding AssistantsAngularApi GatewayAWSAws CdkCloudFormationCloudfrontCognitoDockerDynamoDBEc2EcsEksIamJavaKubernetesLambdaNode.jsPythonRdsReactS3TerraformVue
Reposted 3 Days AgoSaved
Hybrid
San Diego, CA
99K-232K Annually
Senior level
99K-232K Annually
Senior level
Artificial Intelligence • Professional Services • Business Intelligence • Consulting • Cybersecurity • Generative AI
The Manager, Solution Architect at PwC leads digital integration projects, focusing on cloud migration, AI-native development, and mentoring engineering teams while ensuring quality deliverables and strategic architecture design.
Top Skills: .NetAi Coding AssistantsAngularAWSAws CdkCi/Cd PipelinesCloudFormationDockerGithub CopilotJavaKubernetesNode.jsPythonReactTerraformVue
Reposted 5 Days AgoSaved
Remote or Hybrid
San Diego, CA
150K-262K Annually
Senior level
150K-262K Annually
Senior level
Artificial Intelligence • Cloud • HR Tech • Information Technology • Productivity • Software • Automation
The role focuses on designing and validating server configurations while automating deployment processes and resolving performance issues in hyperscaler cloud environments.
Top Skills: AnsibleAWSAzureGCPGitGoLinuxPuppetPython
Reposted 5 Days AgoSaved
Remote or Hybrid
San Diego, CA
129K-219K Annually
Senior level
129K-219K Annually
Senior level
Artificial Intelligence • Cloud • HR Tech • Information Technology • Productivity • Software • Automation
Design and build scalable, high-performance UI components for an AI-native observability platform (90% UI, 10% backend). Lead feature design through delivery, integrate LLMs/RAG and AI tooling, implement automated testing and CI/CD, mentor engineers, and ensure production readiness, observability, and performance across distributed systems.
Top Skills: Ai Orchestration FrameworksAjaxAngularCi/CdCopliot/WindsurfCSSDockerHighchartsHTMLJavaJavaScriptJSONJunitKubernetesLlmsPrometheus Query LanguagePrompt EngineeringPythonRagReactRestSeleniumServicenow PlatformSQLTestngVueXML
Reposted 5 Days AgoSaved
Remote or Hybrid
San Diego, CA
150K-262K Annually
Senior level
150K-262K Annually
Senior level
Artificial Intelligence • Cloud • HR Tech • Information Technology • Productivity • Software • Automation
The role involves collaborating with cloud providers on deployments, designing hardware, automating processes, and troubleshooting performance issues in hyperscale environments.
Top Skills: AnsibleAWSAzureGCPGitGoLinuxPuppetPythonTerraform
Reposted 10 Days AgoSaved
Hybrid
San Diego, CA
130K-222K Annually
Senior level
130K-222K Annually
Senior level
Aerospace • Hardware • Information Technology • Security • Software • Cybersecurity • Defense
The role involves planning, architecting, and developing verification environments for FPGAs, leading teams, mentoring, and improving verification processes.
Top Skills: BitbucketC++CadenceGitJavaJIRAMatlabMentor QuestaPerlPythonSimulinkSystemverilogUvmVhdl
Reposted 10 Days AgoSaved
Remote or Hybrid
San Diego, CA
129K-219K Annually
Senior level
129K-219K Annually
Senior level
Artificial Intelligence • Cloud • HR Tech • Information Technology • Productivity • Software • Automation
As a Senior Systems Engineer, you will manage vulnerabilities in systems, collaborating with teams to ensure compliance and remediation in both cloud and containerized environments.
Top Skills: AWSAzureGCPLinuxPython
Reposted 12 Days AgoSaved
Easy Apply
In-Office
San Diego, CA
Easy Apply
157K-224K Annually
Senior level
157K-224K Annually
Senior level
Machine Learning • Security • Software • Analytics • Defense
The Lead Software Engineer will design, implement, and test software for advanced data communications and networking solutions, mentor junior engineers, and lead technical discussions in a fast-paced environment.
Top Skills: CC++Gnu/LinuxMatlabPython
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Reposted 12 Days AgoSaved
Remote or Hybrid
San Diego, CA
147K-258K Annually
Senior level
147K-258K Annually
Senior level
Artificial Intelligence • Cloud • HR Tech • Information Technology • Productivity • Software • Automation
Design and develop scalable software components, mentor junior engineers, collaborate with product teams, and integrate AI in workflows.
Top Skills: AngularJavaJunitPythonReactSeleniumTestngUnix-Based SystemsVue
Reposted 12 Days AgoSaved
Remote or Hybrid
San Diego, CA
169K-296K Annually
Senior level
169K-296K Annually
Senior level
Artificial Intelligence • Cloud • HR Tech • Information Technology • Productivity • Software • Automation
Design and develop scalable software components with a focus on performance. Collaborate with teams to create user experiences, integrate testing, and enhance product capabilities.
Top Skills: AngularApache KafkaCi/CdJavaJavaScriptJunitPythonReactSeleniumTestng
Reposted 13 Days AgoSaved
Easy Apply
In-Office or Remote
San Diego, CA
Easy Apply
157K-223K Annually
Senior level
157K-223K Annually
Senior level
Machine Learning • Security • Software • Analytics • Defense
As a Lead DevOps Engineer, you'll design and implement CI/CD pipelines, support cloud tools, maintain CI/CD environments, and coach team members on best practices.
Top Skills: AnsibleAWSAzureChefCi/Cd ToolsDockerEksGitlabGCPKubernetesLinuxPodmanPythonRancher
Reposted 14 Days AgoSaved
Easy Apply
In-Office or Remote
San Diego, CA
Easy Apply
157K-224K Annually
Senior level
157K-224K Annually
Senior level
Machine Learning • Security • Software • Analytics • Defense
The Software Test Lead will coordinate testing efforts, design integration tests, maintain automated tests, and ensure system architecture meets end-user needs while managing a team.
Top Skills: DockerDocker-ComposeElk StackGitlabGitlab Ci/CdJavaJestJunitKafkaKubernetesPlaywrightPytestPythonPyunitRestful ServicesSeleniumXunit-Based Test Frameworks
Reposted 14 Days AgoSaved
Easy Apply
In-Office or Remote
San Diego, CA
Easy Apply
157K-224K Annually
Senior level
157K-224K Annually
Senior level
Machine Learning • Security • Software • Analytics • Defense
Lead the development and deployment of software solutions for national security missions, overseeing engineering teams, managing customer relationships, and ensuring product quality.
Top Skills: AWSCi/CdPythonReactTypescript
Reposted 20 Days AgoSaved
In-Office
San Diego, CA
150K-215K Annually
Senior level
150K-215K Annually
Senior level
Artificial Intelligence • Machine Learning • Software • Defense
Vannevar is seeking a Senior Software Engineer to lead the deployment of AI-enabled software products in government environments, focusing on security and compliance. Responsibilities include roadmap ownership, technical design, mentorship, and documentation.
Top Skills: AWSNode.jsPythonReact
Reposted 20 Hours AgoSaved
In-Office
San Diego, CA
141K-207K Annually
Senior level
141K-207K Annually
Senior level
Healthtech • Biotech • Pharmaceutical
The Advisor Lab Automation Software Engineer will design and implement software integrations for lab automation, focusing on AI-driven processes, while providing technical leadership and mentoring.
Top Skills: Ci/CdDockerFastapiFlaskKubernetesPythonRedis
Reposted 20 Hours AgoSaved
In-Office
San Diego, CA
71K-79K Annually
Senior level
71K-79K Annually
Senior level
Fintech • Software • Financial Services
Design, build, and operate automated cloud capabilities while ensuring security and optimal performance. Mentor engineers and contribute to community practices.
Top Skills: Azure DevopsBashGithub ActionsGoogle Cloud PlatformIstioJenkinsKubernetesAzureOpenapiPowershellPythonRestTerraform
Reposted 20 Hours AgoSaved
In-Office
San Diego, CA
121K-164K Annually
Senior level
121K-164K Annually
Senior level
Aerospace • Defense
The Senior Manufacturing Engineer, NPI will develop manufacturing processes for UAV platforms, manage production ramp, and ensure product manufacturability and compliance with standards.
Top Skills: As9100As9102Mes PlatformsPower BIPythonSolidworks
Reposted 20 Hours AgoSaved
In-Office
San Diego, CA
5-10 Annually
Senior level
5-10 Annually
Senior level
Healthtech
Lead the design and delivery of cloud-native digital health solutions on AWS, mentoring engineers, ensuring code quality, and improving CI/CD practices.
Top Skills: AngularAWSCloudFormationDockerGithub ActionsPythonReactTerraform
YesterdaySaved
In-Office or Remote
San Diego, CA
130K-150K Annually
Senior level
130K-150K Annually
Senior level
Beauty
The SDET role focuses on establishing test automation, creating test strategies, integrating testing in CI/CD, and maintaining quality standards across teams.
Top Skills: AWSCi/CdJavaScriptPythonTypescript
YesterdaySaved
In-Office
San Diego, CA
120K-145K Annually
Senior level
120K-145K Annually
Senior level
Fintech
The Sr. Database Administrator will manage SQL Server databases, perform optimization and troubleshooting, and develop data pipelines using Databricks, focusing on enterprise data platforms.
Top Skills: AWSAzureDatabricksPowershellPysparkPythonScalaSQL ServerTsql
Reposted YesterdaySaved
In-Office
San Diego, CA
5-5 Annually
Senior level
5-5 Annually
Senior level
Healthtech
Lead and grow an engineering team focused on delivering digital health solutions on AWS. Oversee technical direction, code quality, and team development while contributing hands-on to software projects.
Top Skills: AWSCdkCi/CdCloudFormationCloudwatchCodepipelineDockerDynamoDBGithub ActionsMySQLPostgresPythonRestful ApisTerraform
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