Top Senior Python Jobs in San Diego, CA

10 Hours AgoSaved
In-Office
San Diego, CA
170K-250K Annually
Senior level
170K-250K Annually
Senior level
Aerospace • Artificial Intelligence • Machine Learning • Robotics • Software
Senior technical lead for unmanned systems (UxS) integration and test readiness. Hands-on role integrating autonomy software with aircraft, onboard compute, radios, sensors, and ground equipment; leading platform evaluation, bench and field bring-up, troubleshooting, test execution, readiness criteria, and mentoring cross-functional teams to improve hardware-based autonomy validation and demonstrations.
Top Skills: ArdupilotBashEmbedded SystemsLinuxMatlabMavlinkMission PlannerNetworkingPixhawk/Cube-Class Flight ControllersPx4PythonQgroundcontrol
YesterdaySaved
In-Office
San Diego, CA
120K-180K Annually
Senior level
120K-180K Annually
Senior level
Aerospace • Artificial Intelligence • Machine Learning • Robotics • Software
Lead integration of autonomy software onto diverse platforms by designing and implementing interfaces between autonomy, vehicle subsystems, sensors, payloads, and communications. Configure Linux mission environments, middleware, containers, and deployment pipelines; support SIL/HIL/VIL validation, field tests, demonstrations, troubleshooting, and cross-team coordination while mentoring junior engineers.
Top Skills: ArdupilotC++Ci/CdContainersLinuxMiddlewarePx4PythonRosRtos
YesterdaySaved
Hybrid
San Diego, CA
133K-226K Annually
Senior level
133K-226K Annually
Senior level
Aerospace • Hardware • Information Technology • Security • Software • Cybersecurity • Defense
Lead design, implementation, and maintenance of on-premises and cloud infrastructure, build CI/CD pipelines, automate provisioning and configuration, monitor and optimize system performance, enforce DevSecOps security practices, troubleshoot production incidents, and collaborate with cross-functional teams to improve reliability and scalability.
Top Skills: AnsibleAws Gc (Govcloud)BashChefDockerDocker SwarmElkGitlabKubernetesLinuxNagiosPowershellPrometheusPuppetPythonRancherUnixVirtualization
YesterdaySaved
Hybrid
San Diego, CA
133K-226K Annually
Senior level
133K-226K Annually
Senior level
Aerospace • Hardware • Information Technology • Security • Software • Cybersecurity • Defense
Lead and develop on-premises and cloud platform infrastructure with a focus on security, scalability, and performance. Build and maintain CI/CD pipelines, automate provisioning/configuration, monitor systems, troubleshoot incidents, and implement DevSecOps best practices across containerized and air-gapped environments while collaborating with cross-functional teams.
Top Skills: Air-Gapped EnvironmentsAnsibleAws GcBashChefCloud ServicesDockerDocker SwarmElkGitlabKubernetesLinuxNagiosPowershellPrometheusPuppetPythonRancherUnixVirtualization
YesterdaySaved
Hybrid
San Diego, CA
133K-226K Annually
Senior level
133K-226K Annually
Senior level
Aerospace • Hardware • Information Technology • Security • Software • Cybersecurity • Defense
Lead design, implementation, and maintenance of on-premises infrastructure and CI/CD pipelines. Automate provisioning and configuration, monitor performance, troubleshoot production incidents, enforce security best practices, and collaborate with cross-functional teams to ensure scalable, reliable, and secure DevSecOps processes in a hybrid environment.
Top Skills: Air Gapped EnvironmentsAnsibleAws GcBashChefCi/CdCloud ServicesContainer OrchestrationDockerDocker SwarmElk StackGitlabKubernetesLinux/UnixNagiosPowershellPrometheusPuppetPythonRancherVirtualization
YesterdaySaved
Hybrid
San Diego, CA
133K-226K Annually
Senior level
133K-226K Annually
Senior level
Aerospace • Hardware • Information Technology • Security • Software • Cybersecurity • Defense
Lead design, implementation, and maintenance of on-prem and cloud (air-gapped/GovCloud) infrastructure. Build and maintain CI/CD pipelines, automate provisioning/configuration, monitor and optimize system performance, enforce DevSecOps security practices, troubleshoot production incidents, and collaborate with cross-functional teams to improve scalability, reliability, and deployment processes.
Top Skills: Air-Gapped EnvironmentsAnsibleAws Govcloud (Aws Gc)BashChefCi/CdDockerDocker SwarmElk StackGitlabKubernetesLinuxNagiosPowershellPrometheusPuppetPythonRancherUnixVirtualization
Reposted 4 Days AgoSaved
Easy Apply
In-Office
San Diego, CA
Easy Apply
140K-170K Annually
Senior level
140K-170K Annually
Senior level
Machine Learning • Security • Software • Analytics • Defense
Design, implement, test, and deploy interactive UX and data-visualization front-end applications for defense programs. Build high-performance components, optimize responsiveness across devices and browsers, integrate geolocation/mapping, containerize deployments (Docker/Kubernetes), collaborate with stakeholders, and produce software documentation and user training materials.
Top Skills: .NetCSSDjangoDockerFlaskGitGoogle Maps ApiHTML5JavaJavaScriptKubernetesLessNode.jsOpenstreetmapPythonReactReduxSassVue
Reposted 4 Days AgoSaved
Hybrid
San Diego, CA
198K-268K Annually
Senior level
198K-268K Annually
Senior level
Artificial Intelligence • Internet of Things • Semiconductor
Drive SoC and server platform performance by characterizing real-world AI/HPC workloads on production silicon, designing microbenchmarks, diagnosing bottlenecks, and translating findings into architectural and system-level optimizations while collaborating with hardware and software teams.
Top Skills: C++CxlInfinibandPciePythonRoceSystemcTlm
Reposted 4 Days AgoSaved
Easy Apply
In-Office
San Diego, CA
Easy Apply
175K-240K Annually
Senior level
175K-240K Annually
Senior level
Machine Learning • Security • Software • Analytics • Defense
Lead DevOps engineer responsible for designing, building, and maintaining CI/CD pipelines and infrastructure across unclassified and classified environments. Support cloud toolsets, manage Kubernetes clusters, ensure security/compliance with DoD standards, liaise with corporate IT, coach teams on DevOps best practices, and operate in a hybrid setting with regular on-site access to government facilities.
Top Skills: AnsibleArgocdArtifactoryAWSAzureBash/Linux ShellChefCoverityDockerEksFluxGitlabGitlab CiGCPJIRAKubernetesNexusPodmanPythonRancherSonarqubeTerraform
Reposted 6 Days AgoSaved
In-Office
San Diego, CA
150K-215K Annually
Senior level
150K-215K Annually
Senior level
Artificial Intelligence • Machine Learning • Software • Defense
Vannevar is seeking a Senior Software Engineer to lead the deployment of AI-enabled software products in government environments, focusing on security and compliance. Responsibilities include roadmap ownership, technical design, mentorship, and documentation.
Top Skills: AWSNode.jsPythonReact
8 Days AgoSaved
Hybrid
San Diego, CA
124K-280K Annually
Senior level
124K-280K Annually
Senior level
Artificial Intelligence • Professional Services • Business Intelligence • Consulting • Cybersecurity • Generative AI
Lead enterprise-scale cloud modernization and migration programs to AWS, design end-to-end architectures (including AI agent integration), define AI-native engineering standards, mentor engineering teams, implement IaC and CI/CD, enforce security and governance, and deliver measurable business value through technical strategy and execution.
Top Skills: AngularApi GatewayAWSAws CdkBedrock Agent SdkCi/CdClaude Agent SdkClaude CodeCloudFormationCloudfrontCloudtrailCloudwatchCodepipelineCodexCognitoCursorDmsDockerDynamoDBEc2EcsEksGithub ActionsGithub CopilotIamJavaJenkinsKiroKubernetesLambdaLangchainMigration HubNode.jsPythonRdsReactS3SctTerraformVueX-Ray
8 Days AgoSaved
Hybrid
San Diego, CA
124K-280K Annually
Senior level
124K-280K Annually
Senior level
Artificial Intelligence • Professional Services • Business Intelligence • Consulting • Cybersecurity • Generative AI
Lead design and delivery of enterprise software solutions, apply systems thinking, implement CI/CD and ATDD, develop teams, engage clients strategically, and oversee architecture and integration.
Top Skills: Application IntegrationAtddCi/CdEnterprise Application ArchitectureJavaScriptKotlinPython
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8 Days AgoSaved
Hybrid
San Diego, CA
99K-232K Annually
Senior level
99K-232K Annually
Senior level
Artificial Intelligence • Professional Services • Business Intelligence • Consulting • Cybersecurity • Generative AI
Lead and manage software engineering teams to design, build, and integrate enterprise applications. Drive coding, testing, code review, CI/CD practices, and mentor staff while overseeing project planning, budgeting, and client delivery to meet timelines and quality standards.
Top Skills: Acceptance Test Driven Development (Atdd)Api ManagementC++Ci/CdJavaJavaScriptPython
Reposted 8 Days AgoSaved
In-Office or Remote
San Diego, CA
220K-330K Annually
Senior level
220K-330K Annually
Senior level
Aerospace • Artificial Intelligence • Machine Learning • Robotics • Software
Lead and grow a team of autonomy engineers to stand up autonomy on novel platforms (space, maritime, rotorcraft), own delivery from design through fielding, write and integrate latency-sensitive autonomy code, coordinate with platform and cross-functional teams, support live tests and deployments, and evolve R&D efforts into longer-term programs.
Top Skills: ArmAtrAutonomy StacksC++Ci/CdCmakeConanDdsDockerEmbedded SystemsHivemindsdkIpcLinuxMessage BusesMotion PlanningOmsPythonShell ScriptingStanag 4586UciVehicle-Control IntegrationVidar
Reposted 8 Days AgoSaved
In-Office or Remote
San Diego, CA
220K-330K Annually
Senior level
220K-330K Annually
Senior level
Aerospace • Artificial Intelligence • Machine Learning • Robotics • Software
Lead and grow a small autonomy engineering team to design, integrate, validate, and field autonomy software for launched effects. Own delivery, hiring, mentoring, technical direction, ICDs, pre-deployment validation, live test support, hardware/software debugging, and cross-team collaboration for multi-agent and air-gapped fleet deployments.
Top Skills: ArdupilotC++Ci/CdCmakeConanCotDdsDockerEmbedded SystemsHivemindsdkK3DK3SLinuxMessage BusesMosaOmsPx4PythonQgroundcontrolQtShell ScriptingTakUciWosa
Reposted 8 Days AgoSaved
In-Office or Remote
San Diego, CA
114K-171K Annually
Senior level
114K-171K Annually
Senior level
Aerospace • Artificial Intelligence • Machine Learning • Robotics • Software
Perform FEA and hand calculations to evaluate and optimize UAV airframe structures. Conduct static, modal, fatigue, and vibration analyses, support structural test planning and data correlation, define loads and material properties, and produce structural analysis reports while collaborating with cross-functional engineering teams.
Top Skills: AnsysExcelFinite Element Analysis (Fea)HyperworksMatlabNastranNxPythonSolidworksTeamcenter
Reposted 8 Days AgoSaved
In-Office
San Diego, CA
110K-170K Annually
Senior level
110K-170K Annually
Senior level
Aerospace • Artificial Intelligence • Machine Learning • Robotics • Software
Hands-on role integrating and flight-testing Hivemind autonomy across Group 1-3 aircraft. Responsibilities include bench and flight bring-up, debugging autonomy/flight controllers/radios, building test tools and automation in Python/C++, developing hardware interfaces, running SIL/HIL/VIL and live flight tests, analyzing data, and improving test infrastructure in collaboration with software, hardware, and flight teams.
Top Skills: ArdupilotC++Ci/CdCube Family (Hardware)Flight ControllersHilMavlinkPx4PythonRadiosRosSilSimulationVilVil
Reposted 8 Days AgoSaved
In-Office
San Diego, CA
170K-240K Annually
Senior level
170K-240K Annually
Senior level
Aerospace • Artificial Intelligence • Machine Learning • Robotics • Software
Lead system-level verification and validation of aircraft software by designing realistic mission test scenarios, managing V&V events to verify flight readiness, writing Python test analyzers, producing coverage and release-readiness reports, and improving simulation and fault-injection capabilities.
Top Skills: C++Hardware EmulationPythonSimulation SoftwareTest Automation Frameworks
Reposted 8 Days AgoSaved
In-Office
San Diego, CA
142K-213K Annually
Senior level
142K-213K Annually
Senior level
Aerospace • Artificial Intelligence • Machine Learning • Robotics • Software
Translate product user stories into clear, testable engineering requirements for the Hivemind SDK. Define, model, and validate system behavior, maintain requirements traceability, support system modeling with SysML/Cameo, and collaborate with Product, QA, and engineering to ensure requirements are implemented and verified.
Top Skills: Automated TestingC++17Cameo Systems ModelerCi/CdDoorsGoJamaJIRALinuxPythonSysml
Reposted 8 Days AgoSaved
Hybrid
San Diego, CA
150K-220K Annually
Senior level
150K-220K Annually
Senior level
Aerospace • Artificial Intelligence • Machine Learning • Robotics • Software
Lead integration and validation of the Hivemind autonomy stack across simulation, HIL, and flight platforms. Configure sensors, drivers, communication interfaces, and platform adapters; develop integration tooling and CI/CD; analyze logs/rosbag to triage defects; collaborate with engineering and product teams to ensure interoperability, release readiness, and end-to-end system compliance.
Top Skills: C++Ci/CdHardware-In-The-Loop (Hil)MiddlewarePythonServer ApplicationsSimulation Tools
Reposted 8 Days AgoSaved
In-Office
San Diego, CA
183K-274K Annually
Senior level
183K-274K Annually
Senior level
Aerospace • Artificial Intelligence • Machine Learning • Robotics • Software
Integrate and deploy autonomy software onto unmanned aircraft, prepare flight-ready systems, support on-site flight tests, debug hardware/software issues, collect and analyze flight data, collaborate across autonomy, GNC, and test teams, and support certification, compliance, and process improvements.
Top Skills: AfsimC++DdsEmbedded SystemsGncLinuxNgtsPythonRosRtosSensor FusionShell Scripting
Reposted 8 Days AgoSaved
In-Office or Remote
San Diego, CA
150K-230K Annually
Senior level
150K-230K Annually
Senior level
Aerospace • Artificial Intelligence • Machine Learning • Robotics • Software
Design, develop, and field high-performance Ground Control Station and C2 software using C++/Qt/QML and QGroundControl. Lead architecture and technical direction, mentor engineers, define APIs/ICDs, debug integration/latency issues, support field tests, implement post-mission debrief tools, and ensure interoperability with C2 standards.
Top Skills: Ai-Assisted Development ToolsCC++CesiumDockerEsriGoGstreamerH.264H.265KubernetesMapboxMavlinkPub-Sub/Ipc MiddlewarePythonQgc Map EngineQgroundcontrol (Qgc)Qt/QmlRtspSerialization/Idl ToolingStanag 4586TcpTypescriptUdpWebrtc
Reposted 8 Days AgoSaved
In-Office or Remote
San Diego, CA
150K-220K Annually
Senior level
150K-220K Annually
Senior level
Aerospace • Artificial Intelligence • Machine Learning • Robotics • Software
Own and maintain native C++ build systems for autonomous aircraft. Improve developer velocity by reducing build/test cycle time, integrate CI with HIL and simulation, implement monitoring and alerts, troubleshoot build/test failures, and collaborate with engineers to design and deploy DevEx/DevOps solutions.
Top Skills: AnsibleAWSAzureAzure DevopsBashC++Cloud Build ClustersCmakeConanCpmDockerGCPGitlabGrafanaHilJenkinsKubernetesPrometheusPythonSimulation EnvironmentsTerraform
Reposted 8 Days AgoSaved
In-Office
San Diego, CA
137K-205K Annually
Senior level
137K-205K Annually
Senior level
Aerospace • Artificial Intelligence • Machine Learning • Robotics • Software
Perform and validate finite element and hand-calculation structural analyses for UAV airframes and components. Develop FEMs, run static/modal/fatigue/vibration studies, support test planning and correlation, define loads/materials/margins, and present structural recommendations while collaborating with cross-functional teams to optimize lightweight aerospace structures.
Top Skills: AnsysExcelFeaHyperworksMatlabNastranNxPythonSolidworksTeamcenter
Reposted 8 Days AgoSaved
In-Office
San Diego, CA
137K-205K Annually
Senior level
137K-205K Annually
Senior level
Aerospace • Artificial Intelligence • Machine Learning • Robotics • Software
Lead development and analysis of aerodynamic and structural load cases for an air vehicle. Perform maneuver, gust, landing, and ground loads (quasi-static and dynamic), aeroelastic stability checks, validate loads with FEA and flight test, coordinate across GNC/aero/structures, produce documentation, and improve loads methodologies and automation.
Top Skills: FeaFemapMatlabNastranPythonSimulink
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