Top Senior Python Jobs in San Diego, CA

Reposted 18 Hours AgoSaved
In-Office
San Diego, CA
150K-215K Annually
Senior level
150K-215K Annually
Senior level
Artificial Intelligence • Machine Learning • Software • Defense
Vannevar is seeking a Senior Software Engineer to lead the deployment of AI-enabled software products in government environments, focusing on security and compliance. Responsibilities include roadmap ownership, technical design, mentorship, and documentation.
Top Skills: AWSNode.jsPythonReact
Reposted YesterdaySaved
Remote or Hybrid
San Diego, CA
129K-219K Annually
Senior level
129K-219K Annually
Senior level
Artificial Intelligence • Cloud • HR Tech • Information Technology • Productivity • Software • Automation
As a Senior Systems Engineer, you will manage vulnerabilities in systems, collaborating with teams to ensure compliance and remediation in both cloud and containerized environments.
Top Skills: AWSAzureGCPLinuxPython
Reposted 3 Days AgoSaved
Remote or Hybrid
San Diego, CA
147K-258K Annually
Senior level
147K-258K Annually
Senior level
Artificial Intelligence • Cloud • HR Tech • Information Technology • Productivity • Software • Automation
Design and develop scalable software components, mentor junior engineers, collaborate with product teams, and integrate AI in workflows.
Top Skills: AngularJavaJunitPythonReactSeleniumTestngUnix-Based SystemsVue
Reposted 3 Days AgoSaved
Remote or Hybrid
San Diego, CA
169K-296K Annually
Senior level
169K-296K Annually
Senior level
Artificial Intelligence • Cloud • HR Tech • Information Technology • Productivity • Software • Automation
Design and develop scalable software components with a focus on performance. Collaborate with teams to create user experiences, integrate testing, and enhance product capabilities.
Top Skills: AngularApache KafkaCi/CdJavaJavaScriptJunitPythonReactSeleniumTestng
Reposted 3 Days AgoSaved
Easy Apply
In-Office
San Diego, CA
Easy Apply
157K-224K Annually
Senior level
157K-224K Annually
Senior level
Machine Learning • Security • Software • Analytics • Defense
The Lead Software Engineer will design, implement, and test software for advanced data communications and networking solutions, mentor junior engineers, and lead technical discussions in a fast-paced environment.
Top Skills: CC++Gnu/LinuxMatlabPython
5 Days AgoSaved
Easy Apply
In-Office
San Diego, CA
Easy Apply
139K-180K Annually
Senior level
139K-180K Annually
Senior level
Machine Learning • Security • Software • Analytics • Defense
The Senior Software Engineer will design and implement software solutions for advanced algorithmic applications, enhancing software architecture and collaborating with different teams and customers to meet national security needs.
Top Skills: C++Ci/CdiOSLinuxMatlabPythonWindows
5 Days AgoSaved
Remote or Hybrid
San Diego, CA
169K-296K Annually
Senior level
169K-296K Annually
Senior level
Artificial Intelligence • Cloud • HR Tech • Information Technology • Productivity • Software • Automation
Lead frontend architecture and engineering practices, design scalable UI components, implement APIs, mentor engineers, and drive AI integration in products.
Top Skills: AngularCss-In-JsCypressHibernateJavaJavaScriptJestKubernetesLit FrameworkMochaPythonReactRestSassSeleniumSpringSQLTestcafe
Reposted 5 Days AgoSaved
Easy Apply
In-Office or Remote
San Diego, CA
Easy Apply
157K-224K Annually
Senior level
157K-224K Annually
Senior level
Machine Learning • Security • Software • Analytics • Defense
The Software Test Lead will coordinate testing efforts, design integration tests, maintain automated tests, and ensure system architecture meets end-user needs while managing a team.
Top Skills: DockerDocker-ComposeElk StackGitlabGitlab Ci/CdJavaJestJunitKafkaKubernetesPlaywrightPytestPythonPyunitRestful ServicesSeleniumXunit-Based Test Frameworks
Reposted 5 Days AgoSaved
Easy Apply
In-Office or Remote
San Diego, CA
Easy Apply
157K-224K Annually
Senior level
157K-224K Annually
Senior level
Machine Learning • Security • Software • Analytics • Defense
Lead the development and deployment of software solutions for national security missions, overseeing engineering teams, managing customer relationships, and ensuring product quality.
Top Skills: AWSCi/CdPythonReactTypescript
Reposted 5 Days AgoSaved
Easy Apply
In-Office or Remote
San Diego, CA
Easy Apply
157K-223K Annually
Senior level
157K-223K Annually
Senior level
Machine Learning • Security • Software • Analytics • Defense
As a Lead DevOps Engineer, you'll design and implement CI/CD pipelines, support cloud tools, maintain CI/CD environments, and coach team members on best practices.
Top Skills: AnsibleAWSAzureChefCi/Cd ToolsDockerEksGitlabGCPKubernetesLinuxPodmanPythonRancher
Reposted 9 Days AgoSaved
Hybrid
San Diego, CA
124K-280K Annually
Senior level
124K-280K Annually
Senior level
Artificial Intelligence • Professional Services • Business Intelligence • Consulting • Cybersecurity • Generative AI
Oversee software engineering projects, lead large-scale distributed data processing systems, mentor junior staff, and drive project success.
Top Skills: Apache NifiContainer Orchestration ToolsDatabase DesignEvent Driven DesignJava 8KafkaMicroservicesPythonRest Api
9 Days AgoSaved
Hybrid
San Diego, CA
124K-280K Annually
Senior level
124K-280K Annually
Senior level
Artificial Intelligence • Professional Services • Business Intelligence • Consulting • Cybersecurity • Generative AI
Lead teams to deliver AWS-based solution architecture, manage cloud migration initiatives, and innovate processes while engaging senior clients. Foster team growth and operational excellence.
Top Skills: ArgocdAWSCloudFormationFluxGithub ActionsGoKubernetesPythonTerraform
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9 Days AgoSaved
Hybrid
San Diego, CA
99K-232K Annually
Senior level
99K-232K Annually
Senior level
Artificial Intelligence • Professional Services • Business Intelligence • Consulting • Cybersecurity • Generative AI
The role focuses on designing and delivering Azure-based cloud solutions, mentoring teams, and driving cloud migration initiatives to enhance client operations.
Top Skills: AksAzureGoInfrastructure As CodeKubernetesPython
9 Days AgoSaved
Hybrid
San Diego, CA
99K-232K Annually
Senior level
99K-232K Annually
Senior level
Artificial Intelligence • Professional Services • Business Intelligence • Consulting • Cybersecurity • Generative AI
Lead the design and implementation of Azure platform solutions, mentor junior staff, and ensure successful project delivery while maintaining high standards.
Top Skills: AzureGoKubernetesPythonTerraform
Reposted 9 Days AgoSaved
Hybrid
San Diego, CA
124K-280K Annually
Senior level
124K-280K Annually
Senior level
Artificial Intelligence • Professional Services • Business Intelligence • Consulting • Cybersecurity • Generative AI
Lead full stack application migrations to AWS, architect solutions, mentor teams, and drive AI-native engineering strategy while ensuring cloud readiness and modernization.
Top Skills: Ai Coding AssistantsAngularApi GatewayAWSAws CdkCloudFormationCloudfrontCognitoDockerDynamoDBEc2EcsEksIamJavaKubernetesLambdaNode.jsPythonRdsReactS3TerraformVue
Reposted 9 Days AgoSaved
Hybrid
San Diego, CA
99K-232K Annually
Senior level
99K-232K Annually
Senior level
Artificial Intelligence • Professional Services • Business Intelligence • Consulting • Cybersecurity • Generative AI
The Manager, Solution Architect at PwC leads digital integration projects, focusing on cloud migration, AI-native development, and mentoring engineering teams while ensuring quality deliverables and strategic architecture design.
Top Skills: .NetAi Coding AssistantsAngularAWSAws CdkCi/Cd PipelinesCloudFormationDockerGithub CopilotJavaKubernetesNode.jsPythonReactTerraformVue
Reposted 11 Days AgoSaved
Remote or Hybrid
San Diego, CA
150K-262K Annually
Senior level
150K-262K Annually
Senior level
Artificial Intelligence • Cloud • HR Tech • Information Technology • Productivity • Software • Automation
The role focuses on designing and validating server configurations while automating deployment processes and resolving performance issues in hyperscaler cloud environments.
Top Skills: AnsibleAWSAzureGCPGitGoLinuxPuppetPython
Reposted 11 Days AgoSaved
Remote or Hybrid
San Diego, CA
129K-219K Annually
Senior level
129K-219K Annually
Senior level
Artificial Intelligence • Cloud • HR Tech • Information Technology • Productivity • Software • Automation
Design and build scalable, high-performance UI components for an AI-native observability platform (90% UI, 10% backend). Lead feature design through delivery, integrate LLMs/RAG and AI tooling, implement automated testing and CI/CD, mentor engineers, and ensure production readiness, observability, and performance across distributed systems.
Top Skills: Ai Orchestration FrameworksAjaxAngularCi/CdCopliot/WindsurfCSSDockerHighchartsHTMLJavaJavaScriptJSONJunitKubernetesLlmsPrometheus Query LanguagePrompt EngineeringPythonRagReactRestSeleniumServicenow PlatformSQLTestngVueXML
Reposted 11 Days AgoSaved
Remote or Hybrid
San Diego, CA
150K-262K Annually
Senior level
150K-262K Annually
Senior level
Artificial Intelligence • Cloud • HR Tech • Information Technology • Productivity • Software • Automation
The role involves collaborating with cloud providers on deployments, designing hardware, automating processes, and troubleshooting performance issues in hyperscale environments.
Top Skills: AnsibleAWSAzureGCPGitGoLinuxPuppetPythonTerraform
Reposted 16 Days AgoSaved
Hybrid
San Diego, CA
130K-222K Annually
Senior level
130K-222K Annually
Senior level
Aerospace • Hardware • Information Technology • Security • Software • Cybersecurity • Defense
The role involves planning, architecting, and developing verification environments for FPGAs, leading teams, mentoring, and improving verification processes.
Top Skills: BitbucketC++CadenceGitJavaJIRAMatlabMentor QuestaPerlPythonSimulinkSystemverilogUvmVhdl
10 Minutes AgoSaved
In-Office
San Diego, CA
87K-198K Annually
Senior level
87K-198K Annually
Senior level
Information Technology
The role involves designing and developing software solutions, leading engineering efforts, and mentoring teams in a fast-paced environment, focused on end-to-end solutions for the Navy's Integrated Communications and Data System.
Top Skills: .NetC#C/C++Ci/CdDevsecopsJavaJavaScriptNode.jsPythonReact
16 Hours AgoSaved
In-Office
San Diego, CA
95K-165K Annually
Senior level
95K-165K Annually
Senior level
Aerospace • Defense
The Senior Flight Test Engineer will lead flight testing for UAVs, design test plans, conduct analysis, ensure safety, and collaborate with engineering teams.
Top Skills: C++MatlabPythonSimulink
16 Hours AgoSaved
In-Office
San Diego, CA
150K-175K Annually
Senior level
150K-175K Annually
Senior level
Healthtech
The Manager/Staff Systems Engineer will lead cross-functional teams to ensure high-quality systems design in medical diagnostics, focusing on integration of engineering components.
Top Skills: ElectronicsMechanical EngineeringPythonSoftware Engineering
16 Hours AgoSaved
In-Office
San Diego, CA
103K-141K Annually
Senior level
103K-141K Annually
Senior level
Healthtech • Biotech • Pharmaceutical
The Senior API Integration Engineer builds and maintains enterprise integrations using Workato and Python. Responsibilities include developing integrations, ensuring operational reliability, implementing secure integration patterns, and collaborating with various teams.
Top Skills: AWSAzureDatabricksGCPJSONJwtOauthPythonRest ApisSQLWorkato
Reposted 18 Hours AgoSaved
In-Office
San Diego, CA
150K-203K Annually
Senior level
150K-203K Annually
Senior level
Artificial Intelligence • Information Technology • Machine Learning • Marketing Tech • Software • Biotech • Design
The Senior Manufacturing Test Engineer leads the development and optimization of manufacturing test solutions, collaborates with cross-functional teams, and drives quality improvements for Oura products.
Top Skills: CC++PythonRust
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