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Top Senior Python Jobs in San Diego, CA

Reposted 10 Hours AgoSaved
Hybrid
San Diego, CA
124K-280K Annually
Senior level
124K-280K Annually
Senior level
Artificial Intelligence • Professional Services • Business Intelligence • Consulting • Cybersecurity • Generative AI
Oversee software engineering projects, lead large-scale distributed data processing systems, mentor junior staff, and drive project success.
Top Skills: Apache NifiContainer Orchestration ToolsDatabase DesignEvent Driven DesignJava 8KafkaMicroservicesPythonRest Api
Reposted 2 Days AgoSaved
Remote or Hybrid
San Diego, CA
132K-230K Annually
Senior level
132K-230K Annually
Senior level
Artificial Intelligence • Cloud • HR Tech • Information Technology • Productivity • Software • Automation
The role involves developing and automating cloud networking solutions, managing deployments, and collaborating with infrastructure architects to enhance network performance.
Top Skills: 802.1QAclsAnsibleBashBfdBgpCisco IosCumulus LinuxGoGrafanaHsrpIpsecIsisJuniper'S JunosKentikMclagNatOspfPrometheusPythonRest ApiSnmpTcpTerraformThousand EyesVrrp
Reposted 4 Days AgoSaved
Remote or Hybrid
San Diego, CA
150K-262K Annually
Senior level
150K-262K Annually
Senior level
Artificial Intelligence • Cloud • HR Tech • Information Technology • Productivity • Software • Automation
The role focuses on designing and validating server configurations while automating deployment processes and resolving performance issues in hyperscaler cloud environments.
Top Skills: AnsibleAWSAzureGCPGitGoLinuxPuppetPython
Reposted 4 Days AgoSaved
Remote or Hybrid
San Diego, CA
125K-213K Annually
Senior level
125K-213K Annually
Senior level
Artificial Intelligence • Cloud • HR Tech • Information Technology • Productivity • Software • Automation
Manage ServiceNow's cloud network infrastructure, resolve network issues, ensure performance, maintain software environments, and automate processes across hybrid clouds.
Top Skills: AnsibleAWSAzureBashBgpDnsDockerF5GCPGitlab Ci/CdKubernetesLinuxNginxPythonTcp/IpTerraformTlsVpns
Reposted 4 Days AgoSaved
Remote or Hybrid
San Diego, CA
169K-296K Annually
Senior level
169K-296K Annually
Senior level
Artificial Intelligence • Cloud • HR Tech • Information Technology • Productivity • Software • Automation
Lead the design and development of interactive applications focusing on AI integration, architecture, and functionality improvements across various technologies, including backend and frontend frameworks.
Top Skills: AjaxAngularjsCSSCycle.JsCyprusHibernateHTMLJavaJavaScriptJestJSONJunitKubernetesMochaPythonReactRestSeleniumSpringTestcafeVue
Reposted 4 Days AgoSaved
Remote or Hybrid
San Diego, CA
129K-219K Annually
Senior level
129K-219K Annually
Senior level
Artificial Intelligence • Cloud • HR Tech • Information Technology • Productivity • Software • Automation
Design and build scalable, high-performance UI components for an AI-native observability platform (90% UI, 10% backend). Lead feature design through delivery, integrate LLMs/RAG and AI tooling, implement automated testing and CI/CD, mentor engineers, and ensure production readiness, observability, and performance across distributed systems.
Top Skills: Ai Orchestration FrameworksAjaxAngularCi/CdCopliot/WindsurfCSSDockerHighchartsHTMLJavaJavaScriptJSONJunitKubernetesLlmsPrometheus Query LanguagePrompt EngineeringPythonRagReactRestSeleniumServicenow PlatformSQLTestngVueXML
Reposted 4 Days AgoSaved
Remote or Hybrid
San Diego, CA
150K-262K Annually
Senior level
150K-262K Annually
Senior level
Artificial Intelligence • Cloud • HR Tech • Information Technology • Productivity • Software • Automation
The role involves collaborating with cloud providers on deployments, designing hardware, automating processes, and troubleshooting performance issues in hyperscale environments.
Top Skills: AnsibleAWSAzureGCPGitGoLinuxPuppetPythonTerraform
Reposted 5 Days AgoSaved
Hybrid
San Diego, CA
130K-222K Annually
Senior level
130K-222K Annually
Senior level
Aerospace • Hardware • Information Technology • Security • Software • Cybersecurity • Defense
The role involves planning, architecting, and developing verification environments for FPGAs, leading teams, mentoring, and improving verification processes.
Top Skills: BitbucketC++CadenceGitJavaJIRAMatlabMentor QuestaPerlPythonSimulinkSystemverilogUvmVhdl
Reposted 6 Days AgoSaved
Hybrid
San Diego, CA
95K-162K Annually
Senior level
95K-162K Annually
Senior level
Aerospace • Hardware • Information Technology • Security • Software • Cybersecurity • Defense
As a Senior Linux System Administrator, you'll manage classified IT systems, ensuring compliance with security standards, maintaining Linux servers, and supporting a secure operational environment.
Top Skills: Active DirectoryLinuxNessusPowershellPythonSplunkTrellix EpoVeeamVMware
Reposted 6 Days AgoSaved
Hybrid
San Diego, CA
99K-232K Annually
Senior level
99K-232K Annually
Senior level
Artificial Intelligence • Professional Services • Business Intelligence • Consulting • Cybersecurity • Generative AI
As a Manager, lead teams to design and develop large-scale distributed systems using programming languages like Java and Python. Mentor junior staff, ensure project success, and maintain high standards while fostering innovation and leveraging technology.
Top Skills: AgileDockerEvent Driven DesignGrafanaJavaJavaScriptKnativeKubernetesMicroservicesPrometheusPythonRest ApiScalaSplunkSpring BootSpring Cloud
Reposted 10 Days AgoSaved
Remote or Hybrid
San Diego, CA
129K-219K Annually
Senior level
129K-219K Annually
Senior level
Artificial Intelligence • Cloud • HR Tech • Information Technology • Productivity • Software • Automation
As a Senior Systems Engineer, you will manage vulnerabilities in systems, collaborating with teams to ensure compliance and remediation in both cloud and containerized environments.
Top Skills: AWSAzureGCPLinuxPython
12 Days AgoSaved
Easy Apply
In-Office
San Diego, CA
Easy Apply
157K-224K Annually
Senior level
157K-224K Annually
Senior level
Machine Learning • Security • Software • Analytics • Defense
The Lead Software Engineer will design, implement, and test software for advanced data communications and networking solutions, mentor junior engineers, and lead technical discussions in a fast-paced environment.
Top Skills: CC++Gnu/LinuxMatlabPython
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Reposted 12 Days AgoSaved
Remote or Hybrid
San Diego, CA
127K-215K Annually
Senior level
127K-215K Annually
Senior level
Artificial Intelligence • Cloud • HR Tech • Information Technology • Productivity • Software • Automation
Lead administration and automation for ServiceNow's global private cloud: build Infrastructure-as-Code, develop Python/Bash/JS tools, drive large-scale automation (patching, provisioning), prepare products for production readiness, and support diverse infrastructure services including databases, messaging, Kubernetes, and monitoring.
Top Skills: AnsibleBashCactiCentos)CfengineChefClouderaDnsIcingaJavaJavaScriptKafkaKubernetesLinux (RedhatLogstashMariadbMySQLNagiosNginxPostgresPuppetPythonRabbitMQRhosp (Red Hat Openstack)Servicenow PlatformSplunkWindsurf
Reposted 12 Days AgoSaved
Remote or Hybrid
San Diego, CA
147K-258K Annually
Senior level
147K-258K Annually
Senior level
Artificial Intelligence • Cloud • HR Tech • Information Technology • Productivity • Software • Automation
Design and develop scalable software components, mentor junior engineers, collaborate with product teams, and integrate AI in workflows.
Top Skills: AngularJavaJunitPythonReactSeleniumTestngUnix-Based SystemsVue
Reposted 12 Days AgoSaved
Remote or Hybrid
San Diego, CA
169K-296K Annually
Senior level
169K-296K Annually
Senior level
Artificial Intelligence • Cloud • HR Tech • Information Technology • Productivity • Software • Automation
Design and develop scalable software components with a focus on performance. Collaborate with teams to create user experiences, integrate testing, and enhance product capabilities.
Top Skills: AngularApache KafkaCi/CdJavaJavaScriptJunitPythonReactSeleniumTestng
Reposted 12 Days AgoSaved
Easy Apply
In-Office
San Diego, CA
Easy Apply
134K-184K Annually
Senior level
134K-184K Annually
Senior level
Machine Learning • Security • Software • Analytics • Defense
The role involves reverse engineering software, developing cybersecurity tools, and analyzing vulnerabilities in cyber physical systems. Requires collaboration in multi-discipline teams and effective documentation and presentation of research.
Top Skills: Afl++Arm AssemblyBinary NinjaC/C++GhidraIda ProPythonQemuX86 Assembly
Reposted 14 Days AgoSaved
In-Office
San Diego, CA
191K-259K Annually
Senior level
191K-259K Annually
Senior level
Artificial Intelligence • Internet of Things • Semiconductor
Responsible for full chip and block level timing closure, developing methodologies, handling timing constraints, and collaborating with multi-functional teams.
Top Skills: PerlPythonSta ToolsTcl
Reposted 16 Days AgoSaved
In-Office
San Diego, CA
150K-215K Annually
Senior level
150K-215K Annually
Senior level
Artificial Intelligence • Machine Learning • Software • Defense
Vannevar is seeking a Senior Software Engineer to lead the deployment of AI-enabled software products in government environments, focusing on security and compliance. Responsibilities include roadmap ownership, technical design, mentorship, and documentation.
Top Skills: AWSNode.jsPythonReact
Reposted 17 Days AgoSaved
Hybrid
San Diego, CA
120K-165K Annually
Senior level
120K-165K Annually
Senior level
Healthtech • Machine Learning • Software • Biotech • Pharmaceutical
Deploy, configure, and optimize molecular modeling and informatics applications in customer cloud/HPC environments. Provide technical solutions, maintain scientific computing resources, support installations and integrations, troubleshoot production issues, and collaborate with product managers, scientists, and developers.
Top Skills: AWSBashContainerized WorkloadsDnsETLFirewallsFlat FilesGpu ComputingHpcJSONKubernetesLinuxNat GatewaysPythonRest ApisRoutingSaml/SsoSQLVpc
18 Days AgoSaved
Hybrid
San Diego, CA
124K-280K Annually
Senior level
124K-280K Annually
Senior level
Artificial Intelligence • Professional Services • Business Intelligence • Consulting • Cybersecurity • Generative AI
Lead full stack application migrations to AWS, architect solutions, mentor teams, and drive AI-native engineering strategy while ensuring cloud readiness and modernization.
Top Skills: Ai Coding AssistantsAngularApi GatewayAWSAws CdkCloudFormationCloudfrontCognitoDockerDynamoDBEc2EcsEksIamJavaKubernetesLambdaNode.jsPythonRdsReactS3TerraformVue
18 Days AgoSaved
Hybrid
San Diego, CA
99K-232K Annually
Senior level
99K-232K Annually
Senior level
Artificial Intelligence • Professional Services • Business Intelligence • Consulting • Cybersecurity • Generative AI
The Manager, Solution Architect at PwC leads digital integration projects, focusing on cloud migration, AI-native development, and mentoring engineering teams while ensuring quality deliverables and strategic architecture design.
Top Skills: .NetAi Coding AssistantsAngularAWSAws CdkCi/Cd PipelinesCloudFormationDockerGithub CopilotJavaKubernetesNode.jsPythonReactTerraformVue
Reposted 20 Days AgoSaved
In-Office
San Diego, CA
109K-147K Annually
Senior level
109K-147K Annually
Senior level
Artificial Intelligence • Internet of Things • Semiconductor
Lead deployment, optimization, and debug of large SoC designs on hardware emulators. Develop automated emulation flows, implement transactors and hybrid co-simulation, integrate IP with RTL/verification/software teams, mentor junior engineers, and drive emulation methodology and performance improvements to accelerate pre-silicon bring-up and software development.
Top Skills: AxiCC++Cadence PalladiumCadence ProtiumDdrDveEthernetFpga PrototypingGitlab CiJenkinsMakefilesPciePerlPythonSiemens VeloceSimvisionSynopsys ZebuSystemverilogTclUsbVerdiVerilogVhdl
YesterdaySaved
In-Office or Remote
San Diego, CA
78K-176K Annually
Senior level
78K-176K Annually
Senior level
Information Technology
As a Senior DevOps Engineer, you will lead automation for naval platforms, mentor junior engineers, and maintain secure deployment pipelines using tools like Ansible and CI/CD processes.
Top Skills: AnsibleAnsible Automation PlatformCi/CdGitPythonRhelVMwareWindows
Reposted YesterdaySaved
In-Office
San Diego, CA
Senior level
Senior level
Information Technology
The Senior Software Engineer will develop AI products, participate in code reviews, manage DevOps pipelines, and improve software for military operations.
Top Skills: C++Ci/CdDatabricksDevOpsDockerGoJavaKubernetesPythonRustSpark
Reposted YesterdaySaved
In-Office
San Diego, CA
106K-189K Annually
Senior level
106K-189K Annually
Senior level
Insurance
The Systems Engineer III manages complex systems and optimizes processes, focusing on cloud and infrastructure technologies and lifecycle support for computing systems.
Top Skills: Active DirectoryAICentos LinuxEntra IdLogicmonitorMicrosoft 365Microsoft SharepointMs PurviewMs Reports & BiOktaOpsgeniePower BIPowerappsPowerautomatePowershellPythonRedhatSplunkVMwareWindows
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