Top Senior IT Jobs in San Diego, CA

3 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
Fintech • Financial Services
Own day-to-day IT and information security operations for a fully remote Mac fleet. Responsibilities include endpoint lifecycle management, identity and access administration, Google Workspace, helpdesk support, asset coordination, CrowdStrike EDR monitoring, DLP controls, Datadog SIEM alerting, security hygiene, access reviews, and SOC 2 and PCI evidence collection. The role requires autonomous ownership, automation, clear documentation, cross-functional collaboration, and approximately 4–6 years of experience beyond ticket-only support.
Top Skills: CrowdstrikeDatadogDlpGoogle WorkspaceJumpcloudmacOSMdmPci DssSIEMSoc 2SsoZero Trust
Reposted 18 Days AgoSaved
Hybrid
San Diego, CA
97K-165K Annually
Senior level
97K-165K Annually
Senior level
Aerospace • Hardware • Information Technology • Security • Software • Cybersecurity • Defense
Manage and support enterprise Windows and Linux server environments, Active Directory, virtualization (VMware), identity services (Azure AD), backup/recovery, endpoint management, and security. Troubleshoot escalations, automate tasks with scripting, support cloud/hybrid initiatives, and collaborate with IT teams for operational efficiency and compliance.
Top Skills: Active DirectoryAuthentication ServicesBackup And Disaster RecoveryBashDhcpDnsEncryption TechnologiesEndpoint ManagementEndpoint SecurityFile ServicesGroup PolicyHorizonLinuxMicrosoft Entra Id (Azure Ad)PowershellPythonStorageVmware VsphereVulnerability Management PlatformsWindows Server
8 Days AgoSaved
Remote
San Diego, CA
100K-132K Annually
Senior level
100K-132K Annually
Senior level
Artificial Intelligence • Beauty • Fitness • Software
Leads strategic execution and delivery of complex cybersecurity and IT programs, managing timelines, risks, resources, prioritization, and stakeholder communication. Develops program templates and progress metrics, resolves blockers, and drives continuous improvement. Applies technical fluency across IAM, endpoint security, cloud risk, compliance frameworks, and system architecture to guide strategy, tradeoffs, and executive communication.
Top Skills: Cloud RiskCybersecurityEndpoint SecurityHitrustIamItNistPci-Dss
Reposted 10 Days AgoSaved
Remote
San Diego, CA
Senior level
Senior level
HR Tech • Professional Services • Consulting • Financial Services
Consult as a Director-level technologist for alternative asset firms and family offices: assess tech practices, advise CTOs, lead application and infrastructure projects, oversee cybersecurity, disaster recovery, vendor selection, KPIs, and team governance to align technology roadmaps with business needs.
Top Skills: AladdinAr/VrBloombergBusiness ContinuityCalypsoConnected DevicesCrdCybersecurityDisaster RecoveryEagleEpamFactsetFull StackIotItMetaverseMobile AppsMurexWeb Apps
17 Days AgoSaved
Easy Apply
Remote
San Diego, CA
Easy Apply
149K-175K Annually
Senior level
149K-175K Annually
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
Owns the strategy and execution of eDiscovery and information governance programs across business functions and enterprise platforms. Partners with engineering teams to improve EDRM capabilities, translates regulatory requirements into system controls, manages roadmaps, dependencies, risks, and audit documentation, and validates compliance tooling through comprehensive testing. The role also identifies automation opportunities, responsibly applies generative AI and workflow tools, and drives organizational adoption.
Top Skills: EdiscoveryElectronic Discovery Reference Model (Edrm)Generative AiGoogle VaultGoogle WorkspaceInformation GovernanceNuixOnnaRelativitySlack
21 Days AgoSaved
In-Office or Remote
San Diego, CA
110K-130K Annually
Senior level
110K-130K Annually
Senior level
Consulting • Cybersecurity
Account Director responsible for acquiring new customers, expanding existing accounts, managing territories, building sales pipelines, and closing complex cybersecurity software and consulting services deals ranging from $50,000 to $2 million. The role partners with consulting teams and security vendors, sells to C-level stakeholders, achieves a $1.1M+ gross profit quota, and develops long-term client relationships.
Top Skills: Advanced Threat DetectionBehavioral AnalysisCybersecurityEndpoint SecurityEnterprise Risk ManagementGovernance Risk And ComplianceItNetworkingPenetration TestingRegulatory ComplianceSecurity Operations
Reposted 18 Days AgoSaved
Easy Apply
Remote
San Diego, CA
Easy Apply
114K-134K Annually
Senior level
114K-134K Annually
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
Lead architecture and delivery of IT automations and integrations across platforms (n8n, Airflow, Temporal, Jira). Act as technical DRI for complex automation projects, partner with Security and IAM, build reusable frameworks and documentation, establish engineering standards and code review practices, and mentor peers.
Top Skills: AirflowCi/CdGenerative AiGitGoogle WorkspaceJIRAJira AutomationN8NOktaSlackSlack ApiTemporalWorkato
Reposted 19 Days AgoSaved
Easy Apply
Remote
San Diego, CA
Easy Apply
115K-194K Annually
Senior level
115K-194K Annually
Senior level
Cloud • Security • Software • Cybersecurity • Automation
Own IT-specific Sarbanes-Oxley (SOX) compliance for ITGCs and ITACs. Assess SOX readiness for systems and process changes, maintain control documentation, coordinate walkthroughs and remediation, liaise with internal/external auditors, review SOC reports, oversee testing programs, and identify automation and AI opportunities to strengthen controls and reporting.
Top Skills: Ai ToolsAuditboardCobitCosoItacItgcSoc ReportsSox
Reposted 20 Days AgoSaved
Easy Apply
Remote
San Diego, CA
Easy Apply
128K-165K Annually
Senior level
128K-165K Annually
Senior level
Healthtech • Pharmaceutical • Telehealth
Own, build, and operate Ro's internal endpoint and VDI systems across macOS, Windows, ChromeOS. Implement IaC, automate workflows (Tines/Okta), deploy software idempotently, contribute to Zero Trust and security tooling (osquery, Santa), support escalations, and participate in on-call rotations while collaborating with IT, Security, and Risk teams.
Top Skills: Agentic ToolingAi Coding AssistantsAWSAzureBashByodChromeosClaude CodeGCPGitmacOSMamMcp-Based IntegrationsMdmOkta WorkflowsOsqueryPythonSantaTerraformTinesVdiWindows
6 Days AgoSaved
In-Office
San Diego, CA
105K-115K Annually
Senior level
105K-115K Annually
Senior level
Travel • Hospitality
Manages IT service delivery, Help Desk personnel, ticket operations, escalations, service metrics, onboarding and offboarding, asset management, vendors, and operational IT projects across multiple hotel properties. The role supervises, coaches, and develops staff; coordinates with systems and network engineers; maintains procedures and documentation; tracks incidents and projects; and serves as the primary IT liaison for hotel and corporate departments.
Top Skills: Asset-Management SystemsBackupsBusiness ApplicationsCloud ServicesCybersecurityIdentity And Access ManagementKnowledge BasesMicrosoft 365NetworksServersTicketing Systems
8 Days AgoSaved
In-Office
San Diego, CA
135K-273K Annually
Senior level
135K-273K Annually
Senior level
Software • Cybersecurity • Big Data Analytics • Automation
Leads a team supporting Linux and Windows systems in physical and virtualized Navy lab environments. Responsibilities include infrastructure installation, provisioning, troubleshooting, hardware and software architecture planning, vulnerability remediation, DISA STIG compliance, RMF preparation, network and virtualization support, documentation, and customer assistance. The role requires collaboration across organizations, workflow leadership, and up to 10% travel.
Top Skills: Cisco SwitchingDisa StigFirewallsLinuxOpenshift VirtualizationRed HatRmfRoutingSubnettingSwitchingTcp/IpVirtual Port ChannelingVlansVMwareVrfsWindows
Reposted 6 Hours AgoSaved
In-Office or Remote
San Diego, CA
Senior level
Senior level
Greentech • Energy • Utilities • Manufacturing
Administer and secure enterprise IT and OT environments across sites, supporting Windows Server, virtualization, networking, cloud (Azure/M365), PLC/SCADA integrations, backups, DR, segmentation and Zero Trust initiatives. Provide Tier 2/3 escalation, network/OT troubleshooting, monitoring, documentation, compliance support, and collaborate with infrastructure, security, and manufacturing teams to maintain production uptime.
Top Skills: Active DirectoryAvevaAzureBackup And RecoveryDhcpDnsEthernet/IpFirewallsGroup PolicyHmiHyper-VHyper-VIamItilMicrosoft 365ModbusOpcPlcScadaTcp/IpVlansVMwareVMwareVpnWindows ServerWirelessZero Trust
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YesterdaySaved
Remote
San Diego, CA
72K-86K Annually
Senior level
72K-86K Annually
Senior level
Healthtech • Pharmaceutical
Partners with IT hiring managers to develop talent acquisition strategies, source and screen candidates, build diverse pipelines, and present qualified talent. Provides recruiting consultation, interview guidance, offer support, vendor coordination, TA systems maintenance, reporting, and special-project leadership. Helps maintain recruiting policies, procedures, communications, and organizational talent acquisition programs while mentoring colleagues and promoting Navitus’ employment brand.
Top Skills: ExcelMicrosoft PowerpointMicrosoft Word
Reposted YesterdaySaved
Remote
San Diego, CA
158K-195K Annually
Senior level
158K-195K Annually
Senior level
Biotech
Owns and leads Regulatory IT systems supporting Global Regulatory Affairs and R&D. Responsibilities include maintaining technology roadmaps, managing system enhancements and implementations, overseeing vendors and releases, providing production support, delivering integrations, conducting data mapping and validation, and ensuring GxP, HIPAA, GDPR, and CCPA compliance. The role serves as the primary IT partner for regulatory business units, manages budgets, and coordinates cross-functional teams delivering regulated technology initiatives.
Top Skills: CcpaCder DirectComputer Software AssuranceComputer System ValidationEctd Submission SystemsEsg WebtraderEsubmission GatewayEudralinkGdprGxpHipaaIdmpIrisLorenz DocubridgeLorenz EvalidatorSdlcSporVeeva Vault PublishingVeeva Vault RegistrationsVeeva Vault RimVeeva Vault SubmissionsVeeva Vault Submissions ArchiveXevmpd
YesterdaySaved
Remote
San Diego, CA
91K-161K Annually
Senior level
91K-161K Annually
Senior level
Consumer Web • Fintech • Insurance
Lead the design and operation of a cloud-first IT environment, including SaaS administration, endpoint management, security, automation, email platforms, and AI-powered workflow agents. The role drives cross-functional IT projects, mentors team members, maintains standards and documentation, resolves complex escalations, and supports onboarding and escalated tickets. Key responsibilities include managing Google Workspace, Proofpoint, Slack, Okta, Jamf, Intune, and related systems while improving reliability, security, and operational efficiency.
Top Skills: Ai Orchestration PlatformsAPIsBashCloud ComputingGoogle WorkspaceJAMFmacOSMicrosoft IntuneOktaProofpointPythonSaaSSlackWindowsZero Trust Network AccessZoom
YesterdaySaved
Remote
San Diego, CA
Senior level
Senior level
Hardware • Information Technology • Security • Consulting • Cybersecurity
Drives revenue growth by managing enterprise accounts, developing strategic sales plans, identifying new opportunities, and expanding customer relationships. Provides consultative guidance on IT solutions including cloud, data center, security, networking, and lifecycle services. Leads proposals, forecasts, pipeline management, cross-functional collaboration, and executive-level customer engagements while representing the company at industry events.
Top Skills: Data CenterHybrid CloudIt Lifecycle ServicesMobilityNetworkingPcsPrivate CloudSecurityServersStorage
YesterdaySaved
Remote
San Diego, CA
Senior level
Senior level
Cloud • Information Technology • Security • Virtual Reality • Cybersecurity
Develops, tests, deploys, and maintains enterprise applications using Microsoft .NET technologies, SQL Server, REST/SOAP services, and modern web tools. Participates in SAFe Agile Scrum ceremonies, CI/CD automation, DevSecOps, secure coding, testing, code reviews, vulnerability remediation, troubleshooting, and application modernization. Collaborates with product owners, developers, testers, stakeholders, and technical teams while supporting documentation, production operations, and software lifecycle delivery for Department of Veterans Affairs systems.
Top Skills: .Net.Net CoreAsp.NetAsp.Net CoreBlazorC#Ci/CdCodeqlCSSDevsecopsEntity FrameworkGitGitGithub DesktopHTMLJavaScriptJIRAJSONMicro Focus FortifyMS OfficeMicrosoft Sql ServerMicrosoft TeamsMstestNunitPowershellRestful ApisSoap Web ServicesSql Server Management StudioTransact-SqlVisual StudioVisual Studio CodeXMLXunit
YesterdaySaved
Remote
San Diego, CA
85K-95K Annually
Senior level
85K-95K Annually
Senior level
Industrial • Manufacturing
Manages and optimizes procurement operations, Coupa workflows, supplier onboarding, purchase orders, invoices, and procurement integrations. Maps and improves business processes, implements ITGC-compliant changes, leads testing and sign-off, develops spend and supplier performance reporting, and resolves invoice and purchase order discrepancies. Drives Coupa Supplier Portal, CXML onboarding, and e-invoicing adoption while partnering with finance, accounts payable, stakeholders, suppliers, and Coupa support.
Top Skills: CoupaCoupa Supplier PortalCxmlE-InvoicingErp SystemsOracleSAP
10 Days AgoSaved
In-Office
San Diego, CA
45-60 Hourly
Senior level
45-60 Hourly
Senior level
Biotech
Support enterprise IT systems, infrastructure, laboratory applications, business platforms, and end users in a regulated biopharmaceutical environment. Responsibilities include SOX and GxP compliance support, ERP and business application administration, helpdesk and onboarding services, Microsoft 365 and identity administration, infrastructure maintenance, backup and disaster recovery, asset procurement, vulnerability remediation, automation, and inspection readiness activities.
Top Skills: 2FaActive DirectoryAIBamboohrClient-Server SystemsCloud InfrastructureConcurData Acquisition SystemsDocusignEqmsFirewallsGroup PolicyLaboratory Instrumentation SystemsMicrosoft 365OktaOn-Premises InfrastructureOracle NetsuiteRipplingSaaSVlansVMwareVpnVsphereWifi
YesterdaySaved
Remote
San Diego, CA
Senior level
Senior level
Artificial Intelligence • Cloud • Information Technology • Software
Leads agile transformation across multiple project teams, establishes program-wide Scrum practices, coaches Scrum Masters, facilitates ceremonies and PI planning, and drives continuous improvement. The role aligns agile delivery with government mission objectives across cloud modernization and legacy system maintenance. It requires scaling agile practices across numerous teams, supporting product roadmapping and retrospectives, and applying AWS and DevOps knowledge to CI/CD and automated testing strategies.
Top Skills: Automated TestingAWSCi/CdDevOpsScrum
YesterdaySaved
Remote
San Diego, CA
Senior level
Senior level
Artificial Intelligence • Cloud • Information Technology • Software
Develop and maintain full-stack web interfaces, backend scoring services, databases, and automated agents for cyber range environments. Responsibilities include architecture, coding, unit and integration testing, system validation, documentation, requirements analysis, and integration with versioned cyber ranges. The role requires collaboration across complex hybrid and multi-vendor environments, with a focus on cyber training systems, infrastructure automation, networking, virtualization, and Agile software development.
Top Skills: AmqpAWSAzureBitbucketDockerExpressGCPGitGithub ActionsGitlab CiJavaScriptJenkinsJqueryKvmLinuxMicroservicesMySQLNode.jsOpenauthPostgresReactRest ApisServerless ArchitecturesSocket.IoTerraformWindows
YesterdaySaved
Remote
San Diego, CA
Senior level
Senior level
Artificial Intelligence • Cloud • Information Technology • Software
Develops and audits government contract pricing models, cost proposals, BOEs, and supporting narratives. Ensures compliance with solicitation requirements, corporate policies, FAR, CAS, and TINA. Reviews complex Excel models for accuracy and traceability, supports pricing policy and training initiatives, provides corrective feedback, and assists with DCAA and DCMA audit preparation. Requires strong government contract pricing or defense auditing experience, advanced Excel and Word skills, regulatory expertise, and exceptional attention to detail.
Top Skills: Cost Accounting StandardsFarExcelMicrosoft WordPropricerTruth In Negotiations Act
YesterdaySaved
Remote
San Diego, CA
Senior level
Senior level
Artificial Intelligence • Cloud • Information Technology • Software
Develop and maintain full-stack web interfaces, backend scoring services, databases, and automated scoring agents for cyber range environments. Responsibilities include architecture, coding, unit and integration testing, documentation, system integration, and collaboration with RangeOS developers. The role requires work across Linux, Windows, virtualization, networking, cloud, hybrid, and multi-vendor environments, with participation in requirements analysis, solution design, Agile development, and cyber training platform integration.
Top Skills: AmqpAWSAzureBitbucketDockerExpressGCPGitGithub ActionsGitlab CiJavaScriptJenkinsJqueryKvmLinuxMySQLNode.jsOpenauthPostgresReactRest ApisSocket.IoTerraformWindows
Senior level
Artificial Intelligence • Cloud • Information Technology • Software
Designs, implements, and maintains security controls for AWS and other cloud environments supporting Federal and DoD systems. Responsibilities include system hardening, vulnerability scanning, monitoring, incident response, log analysis, forensic support, security architecture, access control, patching, AI-related change reviews, compliance with CMMC, SOC 2, and ISO 27001, risk assessments, documentation, and audit readiness.
Top Skills: AWSAzureCmmc Level 2GCPIso/Iec 27001PythonSoc 2
YesterdaySaved
Remote
San Diego, CA
Senior level
Senior level
Artificial Intelligence • Cloud • Information Technology • Software
Provides enterprise technical leadership and architectural governance for application maintenance and modernization. Leads migration from legacy on-premise systems to AWS, establishes architecture standards, reviews major technical decisions, manages risks, and ensures federal security and GSA compliance. Guides cloud, service-oriented, microservice, API-based, event-driven, SecDevOps, legacy modernization, and AI-enabled development strategies while collaborating with government stakeholders and engineering teams.
Top Skills: Agentic AiAIAngularjsAPIsAWSEvent-Driven ArchitectureGoJavaJavaScriptLlmsMicroservicesPHPPythonQueuesRagRustSecdevopsService BusService-Oriented ArchitectureWeb Services
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