Top Senior IT Jobs in San Diego, CA

Leads quality planning, compliance, continuous improvement, and QA inspection processes for technical programs. Owns and updates the Quality Management Plan, manages a 10–15-person quality team, conducts assessments and test analysis, resolves risks, delivers quality reporting and briefings, and coordinates with project managers, government staff, customers, safety teams, and contractors. The role also integrates quality practices into IT and 5G environments and requires approximately 10% travel.

Own IT internal audit projects and portions of the SOX program, including ITGC and ITAC testing, risk assessment, controls evaluation, remediation, and audit reporting. Partner with audit, finance, engineering, process owners, external auditors, and co-sourcing partners. Help establish an AI audit methodology and implement AI-enabled audit efficiencies while maintaining quality, independence, and reliability.

Leads Engine’s distributed IT organization and modernizes its IT function. Responsibilities include managing engineers and support analysts, improving device lifecycle and endpoint security, architecting Okta-based identity and automation, overseeing onboarding and offboarding, establishing support SLAs, partnering with Security and People teams, reducing technical debt, and delivering cross-functional technology programs. The role is hands-on, combining strategic leadership with technical troubleshooting and execution.

Lead a globally distributed IT engineering team building enterprise integrations, workflow automation, orchestration, and AI-native workflows. Set technical direction, establish roadmaps, manage delivery metrics, and partner with business and service operations leaders to eliminate manual work. Guide engineers on architecture, CI/CD, testing, and development practices while evaluating emerging automation and AI tools. Build integrations across identity, ITSM, SaaS, and enterprise systems, and grow team capabilities across US and India time zones.

Consult as a Director-level technologist for alternative asset firms and family offices: assess tech practices, advise CTOs, lead application and infrastructure projects, oversee cybersecurity, disaster recovery, vendor selection, KPIs, and team governance to align technology roadmaps with business needs.

Provides remote and deskside Tier 2 and Tier 3 IT support for employees across company sites. Responsibilities include managing user accounts, configuring workstations, troubleshooting hardware, networks, printers, phones, AV systems, and corporate applications, maintaining technical assets and OS images, supporting validated systems, training users, documenting incidents, and collaborating on infrastructure projects. The role works independently, follows SOPs and change controls, protects system and data security, and provides occasional off-hours support.

Leads Acadia’s commercial Veeva technology portfolio, including Vault CRM, MedComms, and PromoMats. Owns platform strategy, roadmaps, administration, integrations, releases, enhancements, compliance workflows, vendor relationships, and operational support. Partners with Commercial, Medical Affairs, IT, and external managed-service providers to translate business needs into scalable solutions, manage delivery priorities, oversee environments and testing, and drive continuous improvement across regulated GxP platforms.

Own day-to-day IT and information security operations for a fully remote Mac fleet. Responsibilities include endpoint lifecycle management, identity and access administration, Google Workspace, helpdesk support, asset coordination, CrowdStrike EDR monitoring, DLP controls, Datadog SIEM alerting, security hygiene, access reviews, and SOC 2 and PCI evidence collection. The role requires autonomous ownership, automation, clear documentation, cross-functional collaboration, and approximately 4–6 years of experience beyond ticket-only support.

Secures a ServiceNow platform supporting the DoD Blue UAS Cleared List. Responsibilities include architecting security controls, enforcing IL4/IL5 data segregation, maintaining RBAC and security documentation, developing RMF artifacts, managing POA&Ms, coordinating with government stakeholders, conducting continuous monitoring, and supporting ATO compliance. The role requires ServiceNow security expertise, NIST and DoD RMF experience, relevant certifications, and an active or interim DoD security clearance.

Oversee ServiceNow SPM/ITSM implementation and sustainment teams supporting the Blue UAS digital platform. Responsibilities include managing software development lifecycle activities, monitoring Agile metrics, maintaining schedules and risk logs, coordinating technical dependencies, developing ServiceNow dashboards, evaluating technical submissions, and delivering executive status briefings. The role requires federal or DoW ServiceNow project experience, Agile or PMP certification, secure cloud knowledge, and an active or interim DoW clearance.

Lead IT projects from planning through completion across applications, systems, infrastructure, and hardware. Establish project management processes, coordinate stakeholders and vendors, manage scope, schedules, risks, issues, and dependencies, and translate business needs into actionable IT plans. Support the growth of an evolving IT organization and improve project delivery practices.

Leads or supports moderately complex IT initiatives from initiation through stabilization, managing scope, schedules, budgets, risks, issues, dependencies, compliance, validation, governance, and stakeholder communications. Develops project plans, portfolio and steering committee reports, and value-realization measures. Partners with IT and business stakeholders on platform roadmaps, demand intake, and commercial operations initiatives, particularly within clinical and regulatory systems. Requires pharmaceutical IT experience, FDA-regulated validated applications expertise, strong technical knowledge, and project management skills.

Creates and maintains clear business and technical documentation for a complex state Medicaid systems modernization project. Collaborates with project managers, developers, business analysts, SMEs, vendors, and agency stakeholders; translates complex information into accessible documents; develops visual aids; applies templates and style standards; revises deliverables as requirements change; and manages documentation in SharePoint and other repositories.

Supports IT procurement, purchasing, vendor management, third-party risk, privacy, compliance, audit readiness, and governance activities. Responsibilities include RFPs and vendor evaluation, purchase orders and invoice reconciliation, vendor due diligence, contract compliance, policy administration, remediation tracking, business continuity and disaster recovery governance, privacy documentation, reporting, and process improvement. The role also provides guidance to less experienced team members and partners with IT Security, Legal, Privacy, Finance, auditors, vendors, and business teams.

Own the company’s IT roadmap and services, including identity and access management, SaaS administration, endpoint management, employee lifecycle workflows, service delivery, automation, vendors, and IT spending. Administer Okta, Google Workspace, Jamf, and related systems; improve provisioning, support processes, documentation, security controls, and operational scalability. Partner cross-functionally to prioritize initiatives, resolve escalations, manage risks, and deliver reliable IT operations.

Own the IT roadmap and day-to-day technology operations, including Okta identity management, SaaS administration, endpoint management, employee lifecycle workflows, service delivery, automation, vendors, and IT spending. Establish scalable processes, documentation, service metrics, access controls, and support standards while partnering with Security, People Operations, Engineering, and Finance. The role requires hands-on technical execution, cross-functional project leadership, incident resolution, and functional oversight of support activities.

Leads end-to-end delivery of strategic go-to-market technology programs spanning CRM, marketing automation, sales engagement, CPQ, and billing systems. Coordinates cross-functional Business Technology teams, manages scope and milestones, surfaces risks and dependencies, drives stakeholder decisions, and provides executive-level program updates. The role also helps develop AI-enabled program management practices for a growing IT organization.

Lead the design, development, modernization, and governance of enterprise customer-data applications and integrations. Manage operational data stores, system dependencies, IAM integrations, security, compliance, DevOps practices, deployments, and production support. Define target-state architectures, guide technology modernization, oversee vendor teams, troubleshoot critical issues, and communicate technical strategies across business and technology teams while mentoring junior engineers.

Provide senior Oracle database administration for DOE applications across development, test, and production environments. Install, configure, patch, upgrade, monitor, secure, tune, and maintain Oracle databases, Fusion Middleware, WebCenter, OID, OAM, SSO, data warehouses, and ETL processes. Support backup, recovery, disaster recovery, cybersecurity remediation, A&A/ATO activities, incident resolution, documentation, capacity planning, and critical patch management. The role is fully remote but requires U.S. citizenship and the ability to obtain a DOE Q Clearance.

Leads complex, cross-regional IT programs from business case through deployment and stabilization, with emphasis on SAP implementations and transformations. Establishes governance, plans, budgets, risk controls, dependencies, and executive reporting. Coordinates business, technical, data, testing, integration, and deployment teams while managing consulting partners, systems integrators, and vendors. Also supports recovery planning, portfolio prioritization, PMO standards, and coaching of project managers.

Lead the IT workstream for complex business separations, divestitures, and Transition Services Agreements. Manage integrated plans, milestones, dependencies, risks, issues, vendors, and technology impacts across applications, infrastructure, data, cybersecurity, networks, and end-user technology. Coordinate internal teams and service providers, align technology requirements with business needs, and deliver executive reporting and recommendations throughout transition, stabilization, and exit activities.

Administer and secure identity, email, network, firewall, and collaboration infrastructure for a distributed workforce. Responsibilities include Okta or equivalent SSO management, email security controls, incident response, network administration, routing, switching, VPNs, firewall policies, documentation, vendor management, and infrastructure improvement. The role partners with Security and Help Desk teams, troubleshoots complex issues, supports onboarding and offboarding, and manages moderately complex projects independently.

Owns IT infrastructure, endpoint management, identity and access, security, compliance, vendor relationships, and employee support across corporate and clinical teams. The role designs scalable systems, resolves hardware and software issues, manages provisioning and deprovisioning, develops IT policies and documentation, supports HIPAA and SOC 2 compliance, and maintains disaster recovery and cybersecurity response practices. Periodic travel to regional offices is required.

Leads security operations and corporate IT for a healthcare technology company handling PHI. Responsibilities include incident response, application and cloud security, IAM, endpoint management, vendor reviews, security policies, compliance support for HIPAA, SOC 2, and HITRUST, and management of three direct reports. The role also builds AI-driven automation tools and workflows for IT and security operations while partnering with executives, engineers, customers, auditors, and compliance leaders.

Leads IT procurement and strategic sourcing for healthcare technology categories. Develops category strategies, manages competitive sourcing, negotiates complex software, SaaS, cloud, data, and technology-services agreements, and oversees strategic supplier performance throughout the contract lifecycle. Advises senior stakeholders, analyzes costs and risks, supports contracting and implementation, drives savings and supplier consolidation, and promotes consistent procurement practices.