Top Senior IT Jobs in San Diego, CA

Provide IT and business leadership guidance on IT risk management, perform IT security audits and risk assessments, triage alerts/IOCs, administer Microsoft 365/Azure security and related security platforms, assist cloud migrations and Service Manager administration, document service desk resolution, support end users, and produce metrics and SLA reports to ensure compliance and improve controls.

Designs and operates IT services for laboratory environments, including networks, compute, security, private cloud, and SDN platforms. Translates business and IT requirements into secure, standardized architectures and operational processes. Leads deployments, design reviews, documentation, incident gap analysis, automation, and infrastructure optimization. Requires extensive enterprise networking, datacenter, virtualization, Linux, security, and ITIL experience.

Designs and operates laboratory IT services covering compute, networks, security, private and public cloud, and software-defined networking. Translates business requirements into secure, high-performance service offerings; defines architectures, configurations, processes, and operational procedures. Leads implementations, design reviews, documentation, incident analysis, gap remediation, automation, and infrastructure optimization across global laboratory environments.

Lead an Automation Center of Excellence to build and maintain IaC, automation pipelines, and configuration management across colo and multi-cloud (Azure, GCP, OCI). Drive standardization, governance, security controls, CI/CD integration, incident management, GitOps and policy-as-code adoption. Mentor team members, manage vendor relationships, measure automation KPIs, and provide executive reporting. Participate in on-call rotation and work outside normal hours as needed.

Lead and manage a virtualization team operating mixed VMware and Nutanix environments. Ensure availability, performance, security, upgrades, migrations, automation, capacity planning, incident management, vendor relations, KPIs, and alignment with cloud and business objectives.

Lead the implementation of NetSuite solutions, conducting workshops and UAT, while ensuring alignment with client needs and industry best practices.

The Senior IT Project Manager oversees the delivery of technology and business transformation projects, supports PMO standards, manages project risks, and mentors junior managers.

Lead mobile deployment teams for data center operations, ensuring effective execution, operational control, and client communication across various sites.

Build and maintain internal platforms, automations, and integrations to scale IT operations. Own identity, access, lifecycle automation, endpoint trust, SaaS provisioning, and operational reporting. Develop scripts and services (Python, Bash), partner with Security and Engineering for secure AI, Zero Trust, HIPAA and SOC 2 compliance, and apply DevOps/SRE/ITIL practices for monitoring and incident response.

We are looking for a Lead IT Engineer to oversee our IT infrastructure and manage technology-related projects in a dynamic global environment.

The M&A Lead Integration Architect will strategize and implement integration plans for acquired entities, collaborating with various teams to ensure seamless transitions and alignment with business goals.

The IT Applications Business Analyst supports Oracle EBS, translating business needs into solution designs, improving processes, and resolving application issues across various operational sectors.

Lead planning, execution, and delivery of enterprise technology projects. Manage scope, timelines, budgets, resources, risks, vendors, and stakeholder communications across Agile, Scrum, and Waterfall environments. Oversee software development, technology implementations, cloud transformation, application modernization, and other enterprise initiatives while coordinating cross-functional teams and multiple concurrent priorities.

Lead global IT operations for a HIPAA-regulated healthtech company, managing a small support team and hands-on ticketing. Build and maintain systems for compliance and visibility, optimize vendor costs, implement security/onboarding processes, drive process improvements with KPIs and automation, and serve as primary IT liaison to leadership and partners.

Serve as IT Infrastructure Project Manager for public sector clients, delivering networking, wireless, UC, and data center/security projects on time and within budget. Manage schedules, budgets, vendors, stakeholders, risks, QA, and multiple concurrent projects. Provide client-facing communication, financial reporting, and leadership of internal and external teams while ensuring project profitability and adherence to methodology.

Supervise IT staff and manage multi-site infrastructure, networks, servers, endpoints, access controls, physical security systems, vendors, budgets, and technology projects. Maintain data protection and HIPAA safeguards, oversee account provisioning and security incident response, coordinate MSP services, track IT performance, support site openings, and provide escalated technical support. The role requires reliable system availability, proactive risk remediation, accurate access administration, and cross-departmental technology planning.

Designs, deploys, secures, and operates enterprise and service-provider networks across on-premises, colocation, and cloud environments. Manages routing, switching, peering, addressing, firewalls, VPNs, monitoring, automation, capacity planning, and incident response. Maintains documentation and compliance evidence, serves as a technical escalation point, mentors junior engineers, and works directly with customers. The role is remote, includes occasional travel, and requires on-call and after-hours maintenance participation.

Serve as a trusted NetSuite advisor for multiple clients, providing functional support, troubleshooting, configuration, optimization, and solution delivery. Manage enhancement requests and small-to-medium projects across finance, procurement, order management, inventory, projects, and manufacturing. Configure workflows, dashboards, saved searches, KPIs, forms, and custom records; collaborate on scripts and integrations; conduct system reviews; support testing, documentation, change management, SOX compliance, and client relationship management.

Lead a global IT support team, drive AI-first ITSM transformation (ServiceNow->Atomicwork), own ITSM processes and SLA governance, partner on JML/identity automation with Platform Engineering, manage vendors, run cross-functional programs, develop regional specialists, and participate in on-call escalations. Position requires East Coast timezone alignment and ~25% international travel.

Drive national sales and account growth for IT cooling equipment, services, and software. Develop strategic customer relationships, pursue new business, manage channel partners, lead proposals and negotiations, forecast revenue, analyze market trends, and represent the company at industry events. The role requires technical knowledge of HVAC, mission-critical infrastructure, power quality, and data center solutions, along with strong commercial, communication, and relationship-management skills.

Provide frontline and advanced application support for radiology imaging workflows: incident triage, user provisioning, configuration changes, DICOM troubleshooting, monitoring interfaces, coordinating with networks/storage/vendors, maintaining SOPs and knowledge base, delivering end‑user training and on‑call doctor support to meet SLAs.

Lead end-to-end IT sourcing for hardware, software, SaaS, and security services. Develop sourcing strategies, run RFx and negotiations, draft and manage contracts, perform market and TCO analysis, mitigate risks, manage supplier performance, and align cross-functional stakeholders to optimize cost, performance, and vendor portfolios.

The Senior Internal Auditor II - IT evaluates internal controls, supports SOX compliance, collaborates with stakeholders, and provides IT advisory services.

Designs and leads OneTrust Consent Management and Data Discovery architectures for life sciences clients. Integrates OneTrust with Salesforce, Veeva, Databricks, Snowflake, Azure, and AWS; creates ERDs, data dictionaries, and data flow diagrams; translates privacy requirements into technical designs; leads configuration with admins and developers; collaborates with legal, compliance, IT, and delivery teams; supports pre-sales workshops and client engagements. Requires approximately 10–20% travel.

Serve as a functional Commercial CRM Business Analyst for life-sciences CRM implementations. Lead discovery, gather requirements, create user stories and process maps, author UAT/test scripts, support pre-sales scoping, and liaise between business stakeholders, solution architects, and developers to ensure commercial workflows and Agentforce use cases are implemented effectively.