Top Senior IT Jobs in San Diego, CA

Lead and execute demand generation strategy for internal IT buyers: build GTM playbook, run integrated inbound/outbound campaigns, own pipeline metrics and reporting, partner with Sales/Rev Ops/Marketing to drive pipeline and revenue.

Administer and secure DOE’s Oracle Fusion Middleware environment, serving as the primary SME for WebCenter, Enterprise Manager, OID/OAM, and SSL/TLS encryption. Responsibilities include installation, configuration, patching, tuning, monitoring, identity and access management, certificate lifecycle management, compliance with NIST and FedRAMP controls, audit support, remediation, and backup support for broader Oracle technologies. The role also requires collaboration with program managers, security teams, and product SMEs.

Own day-to-day cybersecurity, identity and access hygiene, compliance readiness, and infrastructure security across a multi-site healthcare environment. Administer Microsoft security tools, MFA, Conditional Access, SIEM, email protection, patching, backups, firewalls, and network controls. Lead SOC 2 evidence collection, security reporting, remediation tracking, third-party access reviews, and audit preparation. Direct and verify outsourced IT and offshore resources, enforce SLAs, supervise network work, and communicate risks to nontechnical leaders.

Leads global Workday platform strategy, governance, roadmap, delivery, and operational excellence. Manages Workday technical teams and offshore resources across HCM, talent, recruiting, payroll, integrations, reporting, security, and related modules. Partners with HR, Payroll, and Technology leaders to prioritize investments, oversee enhancements and transformations, manage vendors, budgets, contracts, and business cases, and ensure privacy, compliance, stability, and measurable business value.

Executes Liquidia’s IT compliance program across SOX, GxP, and 21 CFR Part 11 requirements. Manages IT audits, control evidence, corrective actions, third-party risk assessments, infrastructure qualification, validated systems documentation, cybersecurity framework alignment, AI governance records, and external auditor coordination. Partners with Quality, Procurement, Legal, auditors, and IT stakeholders to maintain policies, assess compliance impacts, support validation activities, and mature the cybersecurity governance roadmap.

Maintain and improve cybersecurity across Azure Cloud and on-premises environments. Monitor and tune security alerts, manage vulnerability scanning and remediation, conduct threat intelligence analysis, support incident response, perform risk assessments and threat modeling, and implement security controls and configurations. The role also supports regulatory compliance, security documentation, cross-functional initiatives, and on-call response to security alerts.

Leads Docker’s global Information Technology organization, overseeing help desk services, application management, device lifecycle logistics, internal productivity tools, service metrics, SLAs, and continual improvement. Develops multi-year IT strategy and technology roadmaps, architects and optimizes the SaaS and cloud application ecosystem, manages technical debt, and partners with executives and technical leaders to support business growth. Builds a metrics-driven, customer-focused team and advances AI- and automation-first practices.

Manage ServiceNow implementations and PMO activities for DoD customers onsite in San Diego. Oversee SDLC, integrations, Agile metrics, dashboards, IMS/RIDAC logs, and executive reporting while ensuring DoDM 8140.03 compliance and technical review of submissions.

Architect and configure ServiceNow security controls aligned to DoD Zero Trust, enforce IL4/IL5 segregation, manage RBAC/ACLs and CAC/E-ICAM integrations, develop SSPs and RMF artifacts, support ATO attainment/sustainment, manage POA&M, perform vulnerability assessments and continuous monitoring, produce Security Assessment Reports, and coordinate with Government PMs and AOs.

Support and maintain engineering workspace platforms (Windows VDI, Citrix, Linux HPC), provide first-line support to engineering users, deploy and validate simulation applications, build and maintain CI/CD pipelines and automated functional testing, drive automation and modernization initiatives, monitor performance, and collaborate with global DevOps and infrastructure teams to improve reliability and scalability.

Lead and own the organization's IT and information security program, ensuring HIPAA/HITECH compliance. Manage infrastructure, cloud security, identity, endpoint protection, incident response, vendor risk, audits, disaster recovery, and staff. Develop policies, perform risk assessments, and advise executives to maintain secure, resilient systems and regulatory compliance.

Leads and supports internal IT operations for a globally distributed workforce. Manages a small IT team, oversees infrastructure and systems, improves identity, device, and SaaS tooling, partners across departments on onboarding and security, supports SOC 2 and ISO 27001 compliance, and establishes scalable processes, SLAs, ticketing workflows, and documentation. This is a hands-on player-coach role focused on reliability, security, efficiency, and employee experience.

Manage service delivery for a life sciences-focused MSP pod, overseeing support staff, service quality, SLAs, ticketing, billing accuracy, utilization, capacity planning, escalations, client reviews, onboarding, documentation, and continuous improvement. Ensure delivery aligns with HIPAA, HITECH, GxP, and FDA 21 CFR Part 11 requirements. Coach technical staff, coordinate incident communications, improve PSA workflows, and partner with client executives and customer success managers.

Provides senior technical leadership for IT support and operations in a remote healthcare technology environment. Owns complex escalations, incident resolution, root cause analysis, endpoint and identity administration, onboarding and offboarding, vendor escalations, documentation, automation, and reliability improvements. Coaches support staff, develops scalable processes, partners with Security, Compliance, Engineering, Product, and clinical teams, and communicates clearly during high-impact incidents affecting clinical workflows.

Administer Epic’s corporate identity, access, endpoints, applications, devices, and employee IT support. Manage onboarding and offboarding, access reviews, authentication and device standards, MDM provisioning, asset inventories, procedures, and audit evidence. Support SOC 2 or similar compliance activities, security reviews, and incident response while partnering with infrastructure and people operations. This is a fully remote, US-based role supporting a global engineering team.

Lead administration of Microsoft 365, Google Workspace, SaaS applications, Azure identity, and cloud infrastructure in a fully cloud-based organization. Provide Level 2/3 service desk escalation, execute migrations and cybersecurity projects, establish IT service processes, manage assets and vendors, and support onboarding, offboarding, incident response, change management, and M&A initiatives. The role partners with IT leadership and may help build and manage a growing internal technical team.

The Senior Clinical Trials IT Business Analyst bridges Clinical Development and IT, optimizing clinical trial technologies and managing system implementations, validations, and stakeholder engagement.

Leads enterprise architecture for Biogen’s Veeva ecosystem across Development, Quality, Regulatory, Safety, and Commercial functions. Translates business needs into scalable Veeva configurations and integrations, governs target-state architecture and platform standards, reviews solution designs, and oversees implementation and release planning. Mentors configuration teams, drives cross-vault consistency, manages architecture governance, aligns with Veeva product roadmaps, and advises IT leadership on platform strategy, investments, regulatory compliance, and business objectives.

Leads the design, development, integration, deployment, and operation of large-scale Zero Trust security solutions for DoD environments. Creates system architecture blueprints, selects technologies, integrates distributed systems across on-premise and cloud environments, optimizes performance, ensures compliance with DoD requirements, and leads engineering teams. Diagnoses system issues, implements solutions, and produces architecture documentation while supporting installation, migration, and configuration activities across multiple client locations.

Leads the architecture, design, integration, deployment, and operation of large-scale Zero Trust security solutions for DoD environments. Creates system blueprints, selects technologies, integrates distributed systems across on-premises, cloud, and hybrid environments, optimizes performance, resolves system issues, and ensures compliance with DoD requirements. Leads engineering teams, supports installation and migration at multiple locations, and documents architecture and implementation decisions.

Act as the technical lead for field sales, manage evaluations, deliver on-site and remote demos, prepare SOWs/RFIs/RFPs, respond to security questionnaires, train sales teams, and support sales across U.S. and Canada while maintaining client relationships and achieving technical sales targets.

Sell radiology IT solutions by building strategic account plans, managing long technical sales cycles, maintaining a 3-5× quota pipeline, forecasting in Salesforce, partnering with marketing/inside sales, and representing the company at industry conferences.

Leads business analysis for enterprise applications and reporting initiatives. Translates stakeholder needs into requirements and functional or technical specifications, partners with IT on scalable solutions, manages project scope and risks, maintains process documentation, supports UAT and change readiness, and drives process standardization. Establishes business analysis standards and best practices across a growing, multi-location organization.

The IT Manager, Product Owner - Finance drives financial process transformations, prioritizes product backlogs, and manages stakeholder relationships to ensure high-quality delivery of financial systems solutions.

Lead a team to design, build, and operate scalable, secure platform and MLOps capabilities on GCP and hybrid cloud. Drive DevSecOps, CI/CD, telemetry, and platform modernization to accelerate AI/ML and software delivery while managing delivery, budgets, vendors, and stakeholder alignment.