Top Senior IT Jobs in San Diego, CA

Facilitate IT demand intake, evaluate and prioritize requests, ensure decision-ready business cases, maintain demand/portfolio visibility, coordinate risk and compliance assessments, manage resource capacity and sequencing, and partner with PMO and stakeholders to optimize IT delivery and governance.

Design, deploy, and manage scalable, secure cloud infrastructure. Implement networking, VMs, IaC, and configuration management. Integrate Azure infrastructure into CI/CD pipelines, automate provisioning with DevOps/GitHub Actions, and enforce security/compliance with security teams. Provide Windows Server administration and support enterprise cloud initiatives.

Perform financial analyses for IT, develop Total Cost of Ownership and forecasting models, and recommend financial strategies. Support IT operations/governance, integrate financial checkpoints into governance, and apply Agile delivery principles to align services and outcomes.

Lead and continuously improve the global IT Compliance function for a CRO, ensuring IT governance, ISMS and ISO 27001 certification support, GxP computerised system compliance, audit readiness and vendor/third-party compliance oversight. Provide regulatory guidance, manage audit responses, run risk assessments, maintain compliance documentation, and drive remediation and continual improvement across IT and business stakeholders.

Serve as strategic advisor to assess and optimize end-to-end hospital revenue cycle operations using Epic workflows. Lead performance improvement, analytics, change management, compliance, and operational initiatives to improve financial and patient financial experience.

Provide senior-level remote IT support and operations for a distributed workforce: troubleshoot macOS/Windows/Linux/mobile, manage onboarding/offboarding, administer identity (Rippling/Okta) and MDM, maintain asset inventory, build AI-driven automations (Console.com, Risotto, Unthread), support SOC 2/HIPAA/ISO compliance, write runbooks in Notion, and contribute to the IT roadmap while mentoring the team.

The Senior IT Program Manager leads program development and implementation, ensuring projects align with business needs and are delivered on time and budget. They manage stakeholder relationships and facilitate communication with senior leadership, oversee financial management, and develop risk management strategies.

Lead and execute IT audit and assurance engagements (SOX, SOC 1, SOC 2), perform ITGC/ITAC and automated controls testing, prepare workpapers and RCMs, provide technical guidance to clients, and mentor junior team members while contributing to practice development.

Serve as first-line IT support for hardware, software, networking, and enterprise applications. Triage and resolve support tickets, manage onboarding/offboarding, administer Okta and endpoint management (Intune, Jamf), maintain device health and access controls, collaborate with Security and Engineering, document processes, and improve support workflows to ensure a secure, compliant, and user-friendly hybrid work environment.

The role involves designing and developing enterprise-grade software solutions, integrating AI tools, collaborating with teams, and maintaining documentation while enhancing productivity for Yahoo personnel.

Lead Data QA for the Enterprise Data Warehouse: define QA strategy, design and execute source-to-target validations, CDC and ETL checks, data masking verification, build quality dashboards and automations, mentor QA analysts, manage defects and release readiness, and collaborate with Data Engineering, BI, Product, and stakeholders to ensure data is accurate, complete, and audit-ready.

Lead Veeva CRM implementations for life sciences clients: gather requirements, design processes, support solution design across Veeva modules, manage UAT and data migration, coordinate with architects and PMs, and provide post-go-live support and continuous improvement.

Drive net-new and expansion revenue for CMMC readiness, remediation, Microsoft 365 GCC/GCC High, Azure, and managed services. Prospect, qualify, and close complex cloud and compliance deals; own full sales cycle, manage pipeline in Autotask (or similar), grow MSP/MSSP contracts, and present value to executive, compliance, and technical stakeholders.

Lead enterprise IT sourcing and software procurement for complex renewals and strategic sourcing initiatives. Drive savings, establish governance, create vendor strategies and KPIs, partner with IT and stakeholders, mentor procurement staff, and manage contract negotiations and renewals.

Lead and mentor the Infrastructure team and deliver the enterprise infrastructure roadmap. Design and maintain resilient on-prem and cloud (Azure) network and server environments, oversee capacity planning, monitoring, backup/recovery, disaster recovery, vendor management, and infrastructure automation. Support ERP/Sage X3 infrastructure, collaborate with InfoSec on vulnerability remediation and OT teams for manufacturing environments, and manage infrastructure projects and on-call escalations.

Lead on-site migrations and go-lives for Oracle OPERA Cloud at hotel properties across India. Clean and migrate OPERA data, manage cutovers, and train front desk and management teams. Serve as subject-matter expert bridging hotel operations and OPERA technical deployment.

Lead mobile deployment teams for data center operations. Responsibilities include on-site leadership, operational control, client interface, and team management, while ensuring efficiency and quality during deployments under high-pressure conditions.

Lead network architecture and delivery for MSP engagements across LAN/WAN, SD-WAN, wireless, and network security. Provide pre-sales design, hands-on implementation of Extreme and Fortinet platforms, develop standards and templates, perform network assessments, mentor junior engineers, and represent the practice in client-facing strategy discussions.

Senior, client-facing CRM Solution Architect to design and lead Veeva/IQVIA/Salesforce Life Sciences Cloud implementations for commercial pharma. Responsibilities include solution design, integration architecture, data modeling, security, CI/CD, migration planning, documentation, presales support, and delivery leadership across onshore/offshore teams while supporting regulated delivery needs.

Lead client-facing Salesforce Marketing Cloud engagements for life sciences clients: run discovery and journey mapping, capture requirements, design omnichannel solutions, translate to implementation-ready user stories, coordinate delivery with architects, developers, QA and agencies, and support launch, validation, and post-launch optimization while ensuring regulated documentation and consent controls.

Serve as embedded IT risk partner for engineering and technology teams, owning IT SOX readiness, control design, testing coordination, remediation oversight and auditor liaison. Assess ITGCs and application controls across cloud, DevOps, CI/CD, IAM and Kubernetes environments. Drive control automation, continuous monitoring, evidence quality, and translate technical risks into practical guidance for engineers, Finance, and external auditors.

Own end-to-end delivery of professional services engagements (infrastructure, cloud, Modern Work). Lead initiation, scoping, scheduling, resource coordination, risk and budget management. Act as primary client contact, protect scope and margin, manage change orders, maintain project data in ConnectWise Manage, produce documentation, coordinate cross-functional teams, and contribute to PMO process and tooling improvements.

Hunt and close net-new enterprise and mid-market US-headquartered clients with European operations for multi-country IT hardware procurement. Build pipeline via outbound prospecting, qualify opportunities, create proposals, manage CRM and forecasts, collaborate with regional teams and vendors, represent Presidio at events, and meet revenue and margin targets.

Lead and govern global IT change management lifecycle: intake, risk-based assessment, approvals, execution, validation, post-change review, reporting, and continuous improvement. Coordinate across IT teams, vendors, MSPs, and regions to minimize service disruption, maintain audit-ready records, deliver training, and drive tooling and process automation opportunities to support high-availability and data center operations.

Lead integration of technology into information systems, design data warehouse and BI capabilities, define data architecture and dictionaries, centralize disparate data, design dashboards, document system architecture, perform data quality and management, and provide solution engineering, pilots, and enablement for analytics and resource management.