Top Senior Machine Learning Jobs in Rochester, NY

29 Days AgoSaved
Remote
Rochester, NY
Senior level
Senior level
Biotech
Provides strategic and hands-on biostatistical leadership across pharmaceutical discovery, translational, biomarker, and early research programs. Designs studies, analyzes complex biological datasets, develops advanced statistical methods and reproducible R workflows, and translates evidence into portfolio decisions. The role collaborates with quantitative and scientific functions, supports publications and external partnerships, mentors statisticians, and advances data-driven analytical practices.
Top Skills: Bayesian MethodsCausal InferenceLongitudinal ModelingMachine LearningR
29 Days AgoSaved
Remote
Rochester, NY
180K-240K Annually
Senior level
180K-240K Annually
Senior level
Artificial Intelligence • Software • Travel • Analytics
Own the full enterprise sales cycle for Oversee’s leisure travel business, from prospecting through closing. Build relationships with OTAs, agencies, tour operators, and vacation providers; develop pipeline; identify target segments and use cases; refine positioning and sales strategy; lead complex stakeholder processes; and partner with Product and Engineering to convert market insights into a repeatable leisure sales motion.
Top Skills: Artificial IntelligenceMachine LearningTravel Analytics
29 Days AgoSaved
Remote
Rochester, NY
Senior level
Senior level
Artificial Intelligence • Software • Travel • Analytics
Own AgentSee’s sales and go-to-market strategy as the first dedicated sales leader. Personally close early enterprise opportunities, refine the ideal customer profile, positioning, pricing, packaging, and sales process, and translate AI capabilities into measurable business value. Build repeatable sales operations and playbooks, provide market feedback to Product and Engineering, and eventually hire and lead the AgentSee sales organization.
Top Skills: AIAutomationData AnalyticsMachine LearningSaaSWorkflow Technology
7 Days AgoSaved
Remote or Hybrid
Rochester, NY
170K-240K Annually
Senior level
170K-240K Annually
Senior level
Software
Leads the design, development, deployment, and operation of scalable machine learning solutions and high-performance microservices. Builds real-time inference systems using Triton and TensorRT, guides distributed cloud architectures, participates hands-on in coding and reviews, and mentors engineers. Drives technical strategy, operational excellence, system resilience, and business-wide innovation across generative AI, graph machine learning, and big data initiatives.
Top Skills: Amazon SagemakerAWSAzureBig DataCi/CdDistributed SystemsDockerDocument DatabasesFastapiGCPGraph Machine LearningKubernetesMicroservicesNoSQLPythonPyTorchRestful ApisTensorrtTriton
8 Days AgoSaved
Remote
Rochester, NY
170K-210K Annually
Senior level
170K-210K Annually
Senior level
Other
Lead exploration and application of large language models and generative AI for enterprise contact-center automation. Translate research into high-performing, deployable ML systems; contribute across experimentation, implementation, and deployment; collaborate with engineering and product teams; optimize performance; and help shape team strategy, innovation, and professional growth.
Top Skills: ElasticsearchFaissGenerative AiLarge Language ModelsMachine Learning InfrastructureNatural Language ProcessingPythonPyTorch
8 Days AgoSaved
Remote
Rochester, NY
170K-210K Annually
Senior level
170K-210K Annually
Senior level
Artificial Intelligence • Software • Conversational AI • Automation
Lead exploration and application of large language models and generative AI, translate research into deployable ML systems, and guide strategic direction. Develop solutions across experimentation, implementation, and deployment while collaborating with engineering and product teams to optimize performance and customer outcomes in contact center automation.
Top Skills: ElasticsearchFaissGenerative AiLarge Language ModelsNatural Language ProcessingPythonPyTorch
Reposted 8 Days AgoSaved
Remote
Rochester, NY
Senior level
Senior level
Artificial Intelligence • Fintech • Software • Financial Services
Lead production-grade ML systems: build data pipelines, training and evaluation workflows, and scalable GPU inference. Fine-tune and adapt large models (LoRA, QLoRA, SFT, DPO, distillation), optimize deployments for latency/cost/reliability, and collaborate with product and engineering to ship robust, observable model-driven features.
Top Skills: DistillationDpoGpu-Based Training And InferenceJaxLoraPythonPyTorchQloraSft
Reposted 8 Days AgoSaved
Remote or Hybrid
Rochester, NY
Senior level
Senior level
Artificial Intelligence • Fintech • Software • Financial Services
Lead the end-to-end ML execution: build and operate data pipelines, training and evaluation systems, and scalable inference. Fine-tune and optimize large models (LoRA/QLoRA/SFT/DPO/distillation), ensure GPU efficiency, monitor production quality, collaborate with product and application engineering, and rapidly ship reliable, safe ML solutions that translate research into production.
Top Skills: DistillationDpoGpu-Based Training And InferenceJaxLoraPythonPyTorchQloraSft

Featured Jobs

One Month AgoSaved
Remote
Rochester, NY
Senior level
Senior level
Information Technology • Consulting
Own clinical quality for member-facing AI products by partnering with product, engineering, and clinical teams. Design clinical AI evaluations, define quality thresholds and rubrics, assess accuracy, omissions, hallucinations, medication-safety risks, and translate clinical reasoning into prompts and decision logic. Monitor evolving evidence and standards of care, validate product launches, and communicate findings to technical and clinical audiences.
Top Skills: Clinical AiContext EngineeringLlmsMachine LearningPrompt Engineering
One Month AgoSaved
Remote
Rochester, NY
Senior level
Senior level
Software • Cybersecurity
Manage post-sales relationships with a portfolio of customers, primarily financial institutions, to drive adoption and business outcomes from BioCatch’s behavioral biometric solution. Responsibilities include strategic consulting, project coordination, risk and escalation management, customer presentations, quarterly business reviews, roadmap feedback, stakeholder communication, team coaching, statements of work, and identifying expansion opportunities with account managers.
Top Skills: Behavioral BiometricsBiocatch ConnectMachine Learning
2 Months AgoSaved
Remote
Rochester, NY
224K-336K Annually
Senior level
224K-336K Annually
Senior level
Consumer Web • Healthtech • Professional Services • Social Impact • Software
Lead design and implementation of Headway's insurance systems (eligibility, pricing, matching, claims). Build data-intensive, ML-powered platforms and automation, mentor engineers, write high-impact code, and improve accuracy and reliability across state and payer complexity to scale insurance-covered therapy.
Top Skills: AWSClaudeCursorDatadogEddyFastapiGeminiKafkaMachine LearningNext.JsOcrPagerdutyPostgresPython 3ReactRedisRemixSentrySnowflakeSqlalchemyTemporalTypescript
One Month AgoSaved
Remote
Rochester, NY
118K-169K Annually
Senior level
118K-169K Annually
Senior level
Cloud • Information Technology • Other • Security • Software
Leads business analysis, advanced analytics, KPI development, data modeling, reporting automation, and AI/ML initiatives supporting global data-center construction and operational excellence. Builds datasets, dashboards, performance metrics, forecasts, and scenario models; translates complex findings for executives; aligns technology solutions with business needs; and promotes data governance, documentation, process improvement, and analytics maturity across cross-functional teams.
Top Skills: Artificial IntelligenceDashboardsData ArchitectureData VisualizationMachine LearningExcelPower BIPythonRSQLStatistical ModelingTableau
Reposted 9 Days AgoSaved
Remote or Hybrid
Rochester, NY
180K-250K Annually
Senior level
180K-250K Annually
Senior level
Artificial Intelligence • Professional Services • Consulting • Automation
Design and deploy production recommendation and retrieval engines, build data orchestration pipelines for multiple modalities, implement agentic workflow frameworks, and prototype, optimize, and scale models with monitoring, governance, and low-latency SLAs.
Top Skills: AirflowSparkEmbeddingsKafkaKubernetesLangchainPythonPyTorchRagRetrieval LibrariesServerlessTensorFlowTransformer-Based Models
One Month AgoSaved
Remote
Rochester, NY
180K-205K Annually
Senior level
180K-205K Annually
Senior level
Fashion
Design, deploy, and manage machine learning models supporting client acquisition, retention, and reactivation. Develop Next Best Action, CRM, paid media, and personalization solutions using LLMs and traditional ML. Design and interpret experiments, analyze large-scale datasets, communicate recommendations to stakeholders, and collaborate with product, design, and engineering teams on product and infrastructure roadmaps.
Top Skills: A/B TestingCRMExperimentation FrameworksGenerative AiLarge Language ModelsMachine LearningPaid MediaPythonRecommendation Systems
Reposted 9 Days AgoSaved
In-Office or Remote
Rochester, NY
Senior level
Senior level
Artificial Intelligence • Machine Learning • Software • Analytics
Founding Engineer responsible for building FilmoreAI’s production AI and data platform for construction equipment dealers. The role covers agent infrastructure, model routing, LLM extraction and reasoning, canonical data modeling, entity resolution, Python data pipelines, Azure cloud orchestration, evaluation, observability, and safe human-approved write-back. The engineer will work independently in an ambiguous startup environment and use agentic development tools to ship reliable systems with strong cost, latency, accuracy, and operational guardrails.
Top Skills: AirbyteAzureAzure Blob StorageAzure Container AppsAzure Database For PostgresqlAzure Synapse AnalyticsClaudeCrm ApisDatabricksDatadogDbtFastapiGeminiGithub ActionsGptLangchainLanggraphLangsmithMcpMicrosoft FabricPgvectorPlaywrightPostgresPublic ApisPydantic AiPythonSecret ManagerSQLTemporal CloudTerraformTwilio
One Month AgoSaved
Remote
Rochester, NY
170K-245K Annually
Senior level
170K-245K Annually
Senior level
Healthtech • Other • Telehealth
Design, productionize, and scale machine learning and optimization models, pipelines, libraries, and deployment platforms. Partner with data scientists, engineers, product managers, and business stakeholders to deliver ML capabilities, personalization systems, and reusable end-to-end workflows. Establish ML engineering best practices, troubleshoot data pipelines, mentor junior professionals, and help define BetterHelp’s ML platform strategy.
Top Skills: BoostingData PipelinesDeep LearningDimensionality ReductionDiscrete Event SimulationFine-TuningInteger ProgrammingLarge Language ModelsLinear ProgrammingMachine LearningMachine Learning Deployment PlatformsMachine Learning LibrariesMathematical ModelingNeural NetworksPersonalization SystemsPythonRecommendation SystemsRegressionReinforcement Learning From Human FeedbackSQLStatistical ModelingTree-Based Methods
One Month AgoSaved
Remote
Rochester, NY
128K-173K Annually
Senior level
128K-173K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Manage enterprise metadata, business glossaries, data catalogs, and end-to-end data lineage for a federal case management modernization program. Configure governance and metadata platforms, integrate data sources and pipelines, establish standards and workflows, monitor metadata quality, support compliant data sharing, develop governance metrics, document procedures, and train data stewards and business users.
Top Skills: APIsArtificial IntelligenceBusiness Intelligence PlatformsData CatalogsData LakeData LineageData WarehousingEnterprise DataEtl/EltMachine LearningMetadata Management
One Month AgoSaved
Remote
Rochester, NY
170K-200K Annually
Senior level
170K-200K Annually
Senior level
Artificial Intelligence
Own customer outcomes from discovery through production deployment. Build decision systems using ontologies, reasoning, graph analytics, optimization, and machine learning over enterprise data. Write Python, SQL, and PyRel; debug unfamiliar systems; tune performance; harden deployments; document reusable solutions; and upstream platform improvements. Lead technical workshops and proofs of concept while partnering closely with customers, Product, and Engineering.
Top Skills: BigQueryConstraint SolvingDatabricksGraph AlgorithmsMachine LearningOntologiesOptimizationPyrelPythonRedshiftRelational Knowledge GraphsRule EnginesSnowflakeSQL
One Month AgoSaved
Remote
Rochester, NY
165K-180K Annually
Senior level
165K-180K Annually
Senior level
Artificial Intelligence • HR Tech • Machine Learning • Social Impact • Software • Consulting
Drive new-logo sales and revenue growth for Wonderlic’s talent assessment and employee development solutions. Identify and prospect target clients, build relationships with HR and recruiting decision-makers, manage opportunities through the full sales cycle, close new business, and transition customers to Customer Success. Maintain expertise in products, market trends, and competitive conditions while providing strategic insights. The role requires B2B SaaS and HR technology sales experience, quota achievement, pipeline generation, and experience selling to SMB, mid-market, and enterprise buyers.
Top Skills: Artificial IntelligenceHcmHr TechnologyLmsMachine LearningSaaS
One Month AgoSaved
Remote
Rochester, NY
100K-110K Annually
Senior level
100K-110K Annually
Senior level
Software
Own strategic partnerships with CPG customers, driving measurable outcomes, platform adoption, user expansion, and retention. Analyze usage data and business context to identify risks and opportunities, develop success plans, lead executive and operational relationships, and advocate for customers internally. Collaborate with product, sales, marketing, and support teams while contributing to repeatable playbooks, thought leadership, and customer best practices.
Top Skills: AIMachine LearningPos DataSaas PlatformsTrade Promotion Management Software
One Month AgoSaved
Remote
Rochester, NY
120K-145K Annually
Senior level
120K-145K Annually
Senior level
Aerospace • Manufacturing
Conduct applied research on scalable optimization and resource-allocation algorithms for large communication networks. Apply machine learning, reinforcement learning, integer optimization, graph-based methods, and metaheuristics to improve solution quality and efficiency. Collaborate with software engineers to integrate algorithms into production aerospace networking systems, evaluate performance at realistic scale, publish research, support patent applications, and document novel methods.
Top Skills: CbcDaskGeometric Deep LearningGoogle Or-ToolsGraph TheoryGurobiInteger OptimizationJaxLinuxMachine LearningMetaheuristic AlgorithmsNetwork SciencePythonPyTorchRayReinforcement LearningSatellite CommunicationsSoftware-Defined NetworkingTemporal Graph Neural NetworksTensorFlowWireless Communications
One Month AgoSaved
Remote
Rochester, NY
80K-110K Annually
Senior level
80K-110K Annually
Senior level
Healthtech • Insurance
Manage the operational integrity of an automated group health insurance underwriting workflow. Review and approve RFPs, validate broker and external data, correct errors, monitor funnel and risk metrics, analyze quote-to-bind performance, triage inquiries, coordinate with sales and health plan operations, and maintain underwriting dashboards and reporting.
Top Skills: Artificial IntelligenceMachine LearningExcelPythonSQL
One Month AgoSaved
Remote
Rochester, NY
170K-278K Annually
Senior level
170K-278K Annually
Senior level
Software
Lead AI agent optimization efforts by designing systems that improve token efficiency, response time, reliability, and output quality. Build agentic coding systems, develop AI application patterns, own features end to end, collaborate with engineering and field teams, support the developer community, and create public technical documentation. Work across Python, TypeScript, Java, and Go while serving as a domain expert in agent design and optimization.
Top Skills: APIsAtomicsConcurrency ProgrammingDistributed SystemsGenerative AiGoJavaMachine LearningMutexesOpen Source SoftwarePythonTemporalTypescript
One Month AgoSaved
Remote
Rochester, NY
180K-250K Annually
Senior level
180K-250K Annually
Senior level
Fintech
Design and productionize machine learning, deep learning, LLM, personalization, recommendation, search, and retrieval systems. Collaborate with product, engineering, and analytics teams to deploy AI solutions that improve customer experiences, business growth, and operational efficiency. The role requires driving projects from ideation through deployment and delivering measurable business impact in a fast-moving fintech environment.
Top Skills: Agentic SystemsDeep LearningLarge Language Models (Llms)Machine LearningPersonalization SystemsRecommendation SystemsSearch And Retrieval Systems
Reposted 11 Days AgoSaved
Remote
Rochester, NY
120K-160K Annually
Senior level
120K-160K Annually
Senior level
Artificial Intelligence • Information Technology • Software • Cybersecurity
Own the full lifecycle of production classification and detection models, including transformer fine-tuning, entity detection, behavioral risk scoring, training, serving, versioning, evaluation, drift detection, and retraining. Build SageMaker-based ML systems and define output contracts supporting audit and policy enforcement. Lead the evaluation harness and mentor a co-op while operating as the company’s sole ML engineer.
Top Skills: Amazon EksAmazon SagemakerAWSGrafanaHelmHugging Face TransformersKafkaKinesisPrometheusPythonPyTorchSQLTerraform
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