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Top Senior Python Jobs in Rochester, NY
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Aerospace • Information Technology • Professional Services • Security • Software
Develop and support secure full-stack web applications using Python and JavaScript/TypeScript. Responsibilities include building responsive interfaces, backend services, RESTful APIs, database integrations, automated tests, CI/CD pipelines, and production deployments. The role involves Agile collaboration, code reviews, troubleshooting, monitoring, and secure-development practices. Candidates must hold Top Secret/SCI clearance with CI Poly eligibility, have at least five years of full-stack experience, and be local to Springfield, Virginia or St. Louis, Missouri for periodic onsite access.
Top Skills:
AngularAnsibleAWSAzureAzure DevopsCloudFormationCSS3CypressDastDevsecopsDjangoDockerExpressFastapiFlaskGCPGitGithub ActionsGitlab Ci/CdHelmHTML5JavaScriptJenkinsJestKubernetesMySQLNode.jsNoSQLOauth 2.0Openid ConnectOraclePlaywrightPostgresPytestPythonReactRestful ApisSastSection 508SQL ServerSsoTerraformTypescriptUnittestVueWcag
Artificial Intelligence • Logistics • Software • Transportation
Designs and develops APIs, system integrations, and AI-agent workflows for enterprise applications. Builds integrations with platforms such as Salesforce and REST APIs, deploys and supports solutions on AWS, and develops AI-powered automation using LLMs, tool calling, and multi-step workflows. The role includes client requirements gathering, troubleshooting, reliability optimization, cross-functional collaboration, and mentoring junior developers.
Top Skills:
Ai AgentsApi GatewayAWSEcsLambdaLarge Language Models (Llms)PythonRdsRest ApisSalesforceSnsSqsTerraform
Cloud • Software • Cybersecurity
Designs, develops, deploys, and operates scalable Go and Python microservices in distributed production environments. Responsibilities include API design, Kubernetes deployment, monitoring, scaling, troubleshooting incidents, system architecture, security, testing, code reviews, and continuous improvements to development processes and infrastructure. The role requires end-to-end service ownership, strong Linux and Docker expertise, observability knowledge, and experience with reliability, performance, and CI/CD practices.
Top Skills:
AWSAzureCi/CdClickhouseDatadogDjangoDockerElkFastapiFlaskGCPGitGoGrafanaJwtKeycloakKubernetesLinuxMySQLOauth 2.0OpentelemetryPrometheusPythonRedisRestful Apis
eCommerce • Information Technology • Machine Learning • Marketing Tech • Database • Analytics • Big Data Analytics
Lead backend-focused software architecture and development across distributed systems, data ingestion, experimentation platforms, AI workflows, and product capabilities. Build primarily in Python while contributing to React and TypeScript frontend work. Translate ambiguous product needs into scalable production systems, guide technical direction, partner with product and data teams, mentor engineers, and improve engineering practices.
Top Skills:
Ai WorkflowsAPIsData Processing SystemsDistributed SystemsMicroservicesNear-Real-Time Data InfrastructurePythonReactRole-Based Access Control (Rbac)Typescript
Digital Media • Social Media • Software • Design
Design, develop, and maintain scalable Python applications; collaborate with cross-functional teams to deliver features; ensure performance and quality; identify and fix bugs; maintain code quality and automation; lead and mentor team members using agile practices.
Top Skills:
Python
Artificial Intelligence • Machine Learning • Natural Language Processing • Software • Generative AI
Develop and maintain open-source Python frameworks and ML developer tools, architect scalable libraries, grow early-stage projects, build real-time streaming capabilities, integrate modern frontend technologies, and collaborate with open-source contributors and the broader developer community.
Top Skills:
JavaScriptPythonReactSvelteTypescriptWebrtcWebsockets
Digital Media • Software
Modernize legacy SAS data-processing systems by translating logic into scalable, high-performance Python solutions. Build and optimize large-scale data pipelines using formats including SAS, Parquet, JSON, and SQL. Integrate PostgreSQL, implement parallel processing, automated testing, data validation, and quality assurance, and maintain well-documented code. Collaborate with IT specialists and stakeholders to validate requirements, troubleshoot issues, and deliver cloud-native modernization solutions.
Top Skills:
AWSDaskGitJSONLinuxMultiprocessingParquetPostgresPysparkPythonSASSQL
Big Data • Cloud • Software • Database
The Senior Python Engineer will develop and support MongoDB Python drivers, enhance library quality, and collaborate on product features.
Top Skills:
Ai/Ml FrameworksMongoDBPypiPython
Healthtech • Pharmaceutical • Hospitality
Build and maintain scalable backend applications, serverless functions, microservices, data workflows, ETL pipelines, and cloud-native architectures using Python and AWS. Manage databases, APIs, batch jobs, and real-time integrations while optimizing performance, scalability, security, compliance, and cost. Collaborate with product, engineering, analytics, and data teams; contribute to architecture, CI/CD, infrastructure automation, development standards, and technical mentorship. Healthcare claims data experience is required.
Top Skills:
Amazon Api GatewayAmazon AuroraAmazon KinesisAmazon RdsAmazon RedshiftAmazon S3AWSAws GlueAws LambdaAws Step FunctionsCi/CdData LakesData WarehousesDevOpsETLHipaaHl7Infrastructure As CodeMicroservicesMySQLPostgresPythonServerless ComputingSQLStored Procedures
Artificial Intelligence • Computer Vision • Machine Learning • Analytics
Develop open source SDKs, enterprise APIs, UIs, and backend systems supporting large-scale computer vision datasets. Build scalable, maintainable, performant, and well-tested software for unstructured data and AI workflows. Contribute to enterprise deployments across customer clouds and on-premises environments, while improving tooling, automation, engineering practices, and open source community initiatives in a remote-first team.
Top Skills:
DocumentdbElasticsearchMongoDBPythonTypescript
Agency • Information Technology • Software • App development
Design, develop, and maintain scalable Python applications and cloud-native solutions. Architect microservices, containerized deployments (Docker/Kubernetes), optimize cloud infrastructure, build CI/CD pipelines, integrate messaging systems, ensure security and high code quality, and mentor junior developers. Generative AI/ML experience is a plus.
Top Skills:
AWSAzureAzure PipelinesCi/CdCosmosdbDjangoDockerFastapiFlaskGenerative AiGitlab CiGCPHugging FaceJenkinsKafkaKubernetesPythonPyTorchRabbitMQRdsRest ApisServerlessTensorFlowWebsockets
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Machine Learning • Other
The Backend Software Engineer will develop and maintain backend systems for data processing related to coffee farming, utilizing Python and PostgreSQL. Responsibilities include feature development, problem-solving, and adapting systems to regulatory changes while ensuring system resilience.
Top Skills:
AWSCi/CdDockerPostgresPostgresql/PostgisPythonTerraform
Artificial Intelligence • Information Technology • Professional Services • Software
The Senior Full Stack Developer will design, develop, test, and debug software solutions, collaborating with teams and optimizing applications. Responsibilities include user interaction design, back-end functionality, and ensuring software scalability and security.
Top Skills:
CSSDjangoDockerFastapiFlaskGitGnu/LinuxHTMLJavaScriptMongoDBMySQLNode.jsOraclePostgresPythonReactSvnVue
Artificial Intelligence • Information Technology • Machine Learning • Software • Analytics • Consulting • Financial Services
Develop, test, and maintain a complex distributed processing application using Python and Java. Collaborate with product owners, data coaches, analysts, DBAs, and Agile teams to meet backend/frontend requirements. Work with distributed workloads (Spark/Hadoop), SQL/Snowflake, AWS, shell scripting, and job scheduling/process automation. Support delivery under Agile/SAFe practices and ensure alignment with program standards.
Top Skills:
AWSBash/Shell ScriptingDroolsHadoopJavaLinux (Cli)OdmPythonSnowflakeSparkSQLVs Code
Reposted One Month AgoSaved
Travel
Lead development of Python-based web applications using Django and FastAPI, architect scalable solutions, and establish technical standards while mentoring developers and optimizing infrastructure.
Top Skills:
Ai Coding AssistantsAWSDjangoFastapiGitPostgresPythonRailway
Cloud • Software
The Python Engineer will write maintainable Python software, lead technical initiatives, collaborate globally, and contribute to community engagement at Canonical.
Top Skills:
CC++DockerGoKubernetesLinuxNoSQLPythonRustSQL
Digital Media
Develop and enhance features for EnrollWise, contribute to a scalable software architecture, review code, collaborate on design and technical feasibility, and maintain software quality.
Top Skills:
ApolloAWSDjangoDjango OrmGraphQLNextjsPythonReact
Information Technology • Software • Consulting
Build and maintain full-stack wealth management platform features using Python and Angular or React. Design service-oriented architectures and REST/SOAP APIs, work with relational databases and ORMs, contribute to AWS or Azure cloud architecture, and deploy using container technologies. Collaborate in Agile/Scrum ceremonies, participate in code reviews and demos, and work independently with distributed teams.
Top Skills:
AngularAWSAzureConfluenceDjangoDockerEcsFlaskJavaScriptJIRAJSONKubernetesMySQLOracleOrmPostgresPythonReactRestSoapSQLSQL Server
eCommerce • Information Technology • Machine Learning • Marketing Tech • Database • Analytics • Big Data Analytics
Design and implement scalable backend and distributed systems for a marketing intelligence platform. Build near-real-time ingestion and processing, scale an incrementality/experimentation product, integrate AI-powered workflows, improve data ingestion/exports and connection-state systems, and contribute frontend components to deliver end-to-end product experiences.
Top Skills:
AIAPIsData ProcessingDistributed SystemsMachine LearningMicroservicesPythonRbacReactReal-Time Data IngestionTypescript
Artificial Intelligence • HR Tech • Information Technology • Software
As a Founding Staff Software Engineer, you will lead the design and development of robust backend systems and APIs, optimize large-scale data workflows, and mentor a growing engineering team.
Top Skills:
AWSCeleryFastapiOpensearchPostgresPythonRedisTemporal
Software • Cybersecurity
The Forward Deployed Engineer will serve as a technical bridge between clients and engineering teams, writing custom code and integrations, while ensuring customer success with Socket's security platform through strong relationships and expert technical guidance.
Top Skills:
Automation ScriptsCi/CdDevOpsPythonSastWebhook Implementations
Information Technology • Consulting
Design and build applications using Python, manage component design, optimize performance, and collaborate with clients on innovative products.
Top Skills:
Ai ToolsCi/CdGitGoKubernetesPythonReact
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