Top Senior IT Jobs in Houston, TX

Owns the enterprise Power BI ecosystem, including data modeling, ETL/ELT pipelines, dashboards, reporting, administration, governance, security, and support. Leads BI implementations, platform maintenance, testing, documentation, process improvements, stakeholder training, and adoption of Microsoft Fabric, Databricks, and AI-enabled analytics. Requires strong Power BI and Azure Data Factory expertise, business requirements translation, analytical problem-solving, communication, and potential people leadership. Travel up to 20% domestically and internationally is required.

Coordinates testing for Epic applications and integrated healthcare systems, including test planning, user acceptance testing, defect management, upgrades, implementations, documentation, and compliance. Provides tier-2 application support, resolves complex system issues, supports optimization and enhancements, collaborates with stakeholders and vendors, facilitates governance meetings, and mentors junior analysts. The role also requires advanced AI literacy, healthcare operations knowledge, and independent leadership across application support and delivery initiatives.

Leads IT service and support across North American waste and recycling operations. Manages a geographically dispersed technician team, develops talent, sets performance expectations, oversees multi-site IT lifecycles, aligns technology initiatives with business leaders, manages OpEx and CapEx budgets, and leads regional hardware, networking, and facility technology deployments. Requires a hands-on leadership style with substantial travel to operational sites.

Drive sales growth for LG IT solutions across the Central Region through consultative selling, territory planning, account development, and partner collaboration. Build enterprise and commercial customer relationships, manage opportunities from discovery through close, coordinate pricing and forecasting, maintain Salesforce pipeline data, and achieve revenue and sales objectives. The role involves executive engagement, customer presentations, trade shows, and approximately 70–75% regional travel.

Administer and secure DOE’s Oracle Fusion Middleware environment, serving as the primary SME for WebCenter, Enterprise Manager, OID/OAM, and SSL/TLS encryption. Responsibilities include installation, configuration, patching, tuning, monitoring, identity and access management, certificate lifecycle management, compliance with NIST and FedRAMP controls, audit support, remediation, and backup support for broader Oracle technologies. The role also requires collaboration with program managers, security teams, and product SMEs.

Act as liaison between U.S. operations and global headquarters to coordinate IT initiatives, drive digital transformation, analyze business requirements, recommend technology solutions, and provide operational end-user support. Focus areas include Microsoft 365, cloud, AI, cybersecurity, and enterprise applications while facilitating cross-cultural communication and collaboration.

Own day-to-day cybersecurity, identity and access hygiene, compliance readiness, and infrastructure security across a multi-site healthcare environment. Administer Microsoft security tools, MFA, Conditional Access, SIEM, email protection, patching, backups, firewalls, and network controls. Lead SOC 2 evidence collection, security reporting, remediation tracking, third-party access reviews, and audit preparation. Direct and verify outsourced IT and offshore resources, enforce SLAs, supervise network work, and communicate risks to nontechnical leaders.

Leads global Workday platform strategy, governance, roadmap, delivery, and operational excellence. Manages Workday technical teams and offshore resources across HCM, talent, recruiting, payroll, integrations, reporting, security, and related modules. Partners with HR, Payroll, and Technology leaders to prioritize investments, oversee enhancements and transformations, manage vendors, budgets, contracts, and business cases, and ensure privacy, compliance, stability, and measurable business value.

Executes Liquidia’s IT compliance program across SOX, GxP, and 21 CFR Part 11 requirements. Manages IT audits, control evidence, corrective actions, third-party risk assessments, infrastructure qualification, validated systems documentation, cybersecurity framework alignment, AI governance records, and external auditor coordination. Partners with Quality, Procurement, Legal, auditors, and IT stakeholders to maintain policies, assess compliance impacts, support validation activities, and mature the cybersecurity governance roadmap.

Leads Docker’s global Information Technology organization, overseeing help desk services, application management, device lifecycle logistics, internal productivity tools, service metrics, SLAs, and continual improvement. Develops multi-year IT strategy and technology roadmaps, architects and optimizes the SaaS and cloud application ecosystem, manages technical debt, and partners with executives and technical leaders to support business growth. Builds a metrics-driven, customer-focused team and advances AI- and automation-first practices.

Senior IT Business Analyst supporting Trading & Supply technology, focusing on Endur implementations and enhancements. Gather and document requirements, translate to functional/technical specs, support testing and deployment, maintain traceability, and collaborate with developers, architects, vendors, and QA in Agile environments to improve processes and deliver solutions.

Lead security architect for Azure and AI technologies, defining AI security strategy, reference architectures, guardrails, and governance. Collaborates with data, privacy, infrastructure, and business teams to secure data, cloud workloads, and AI/ML solutions, perform risk assessments, and guide secure-by-design implementation across cloud and AI environments.

Design and maintain enterprise SCADA architectures, translate business needs into reusable design strategies, integrate SCADA with enterprise systems, improve system efficiency, implement cybersecurity, mentor teams, and support on-call leadership. Develop roadmaps, perform design reviews, and incorporate emerging technologies like ML/AI.

Design, configure, and maintain security controls across endpoints, networks, applications, and cloud; investigate and remediate complex security issues; monitor threats and vulnerabilities; mentor junior engineers; collaborate with IT and business partners to embed security and communicate risks to stakeholders.

Provides senior technical leadership for IT support and operations in a remote healthcare technology environment. Owns complex escalations, incident resolution, root cause analysis, endpoint and identity administration, onboarding and offboarding, vendor escalations, documentation, automation, and reliability improvements. Coaches support staff, develops scalable processes, partners with Security, Compliance, Engineering, Product, and clinical teams, and communicates clearly during high-impact incidents affecting clinical workflows.

Lead SOX IT controls and IT audit activities: document controls, perform walkthroughs and testing, analyze evidence and data, support external audits, drive remediation, and improve governance aligned with SOX, NIST, and ISO requirements while partnering with IT, cybersecurity, finance and business stakeholders.

Lead IT infrastructure, applications, cybersecurity, and support for HQ and 12+ service centers. Manage MSP/vendor relationships, ERP/CRM administration, incident response, backups, field support, IT budget, and roadmap; mentor staff and drive technology-enabled process improvements.

The Sr. Director of Global IT Networking will lead the global network strategy, focusing on zero-trust security and data center networks, while managing a high-performing team and collaborating with R&D to innovate network solutions.

Administer Epic’s corporate identity, access, endpoints, applications, devices, and employee IT support. Manage onboarding and offboarding, access reviews, authentication and device standards, MDM provisioning, asset inventories, procedures, and audit evidence. Support SOC 2 or similar compliance activities, security reviews, and incident response while partnering with infrastructure and people operations. This is a fully remote, US-based role supporting a global engineering team.

Build and lead DESRI's internal IT function: define IT strategy and governance, manage infrastructure and enterprise applications (Microsoft 365, HRIS), lead cybersecurity and compliance, oversee vendor and budget management, establish service delivery and Help Desk, and scale a global IT team to support distributed operations and remote employees.

Lead administration of Microsoft 365, Google Workspace, SaaS applications, Azure identity, and cloud infrastructure in a fully cloud-based organization. Provide Level 2/3 service desk escalation, execute migrations and cybersecurity projects, establish IT service processes, manage assets and vendors, and support onboarding, offboarding, incident response, change management, and M&A initiatives. The role partners with IT leadership and may help build and manage a growing internal technical team.

The Senior Clinical Trials IT Business Analyst bridges Clinical Development and IT, optimizing clinical trial technologies and managing system implementations, validations, and stakeholder engagement.

Leads enterprise architecture for Biogen’s Veeva ecosystem across Development, Quality, Regulatory, Safety, and Commercial functions. Translates business needs into scalable Veeva configurations and integrations, governs target-state architecture and platform standards, reviews solution designs, and oversees implementation and release planning. Mentors configuration teams, drives cross-vault consistency, manages architecture governance, aligns with Veeva product roadmaps, and advises IT leadership on platform strategy, investments, regulatory compliance, and business objectives.

Leads the design, development, integration, deployment, and operation of large-scale Zero Trust security solutions for DoD environments. Creates system architecture blueprints, selects technologies, integrates distributed systems across on-premise and cloud environments, optimizes performance, ensures compliance with DoD requirements, and leads engineering teams. Diagnoses system issues, implements solutions, and produces architecture documentation while supporting installation, migration, and configuration activities across multiple client locations.

Leads the architecture, design, integration, deployment, and operation of large-scale Zero Trust security solutions for DoD environments. Creates system blueprints, selects technologies, integrates distributed systems across on-premises, cloud, and hybrid environments, optimizes performance, resolves system issues, and ensures compliance with DoD requirements. Leads engineering teams, supports installation and migration at multiple locations, and documents architecture and implementation decisions.