Top Senior IT Jobs in Houston, TX

Leads complex federal platform, cloud infrastructure, IT services, security, compliance, and disaster recovery initiatives. Coordinates AWS GovCloud infrastructure-as-code, deployment automation, observability, Zero Trust identity programs, FedRAMP High and DoD IL5 readiness, and operational resilience. Partners across Engineering, Security, Compliance, and Product to manage roadmaps, dependencies, risks, milestones, and audit readiness. The role also builds and mentors a Federal Platform Operations team and drives reliable, repeatable delivery practices.

Sell radiology IT solutions by building strategic account plans, managing long technical sales cycles, maintaining a 3-5× quota pipeline, forecasting in Salesforce, partnering with marketing/inside sales, and representing the company at industry conferences.

Leads business analysis for enterprise applications and reporting initiatives. Translates stakeholder needs into requirements and functional or technical specifications, partners with IT on scalable solutions, manages project scope and risks, maintains process documentation, supports UAT and change readiness, and drives process standardization. Establishes business analysis standards and best practices across a growing, multi-location organization.

The IT Manager, Product Owner - Finance drives financial process transformations, prioritizes product backlogs, and manages stakeholder relationships to ensure high-quality delivery of financial systems solutions.

Lead a team to design, build, and operate scalable, secure platform and MLOps capabilities on GCP and hybrid cloud. Drive DevSecOps, CI/CD, telemetry, and platform modernization to accelerate AI/ML and software delivery while managing delivery, budgets, vendors, and stakeholder alignment.

The IT Project Manager will oversee project planning, implementation, and client interactions while ensuring compliance with federal and state regulations in the public sector.

The IT Project Manager will lead public sector ERP migration projects, ensuring high-quality deliverables and strategic alignment while collaborating with various stakeholders.

Lead global IT sourcing strategy and a multi-year technology modernization agenda. Manage $450M spend, strategic supplier relationships, governance, risk, and value delivery. Oversee category management (cloud, software, infrastructure, cyber), negotiations with hyperscalers and SaaS vendors, stakeholder engagement, and build a high-performing sourcing organization.

Support, administer, secure, and improve OT and industrial IT systems (PCS, PIMS, LIMS, historian, analytics) across manufacturing and lab sites. Perform infrastructure administration, network and endpoint security, virtualization management, backups/disaster recovery, system integrations, Level 1/2 support, documentation, and participate in OT projects and audits.

Lead and manage the IT General Controls (ITGC) program for SOX compliance, supervising two analysts, coordinating control design/testing and risk assessments, liaising with internal and external auditors, tracking remediation, producing executive reporting, and driving continuous improvement and automation across access, change management, and IT operations.

Lead the Energy Technology pod delivering and operating market-critical trading, forecasting, scheduling, settlement, and generation platforms. Own the product roadmap, prioritize backlog, manage deliveries and vendors, ensure operational reliability, and translate energy-market requirements into technical solutions while aligning with enterprise IT standards.

Designs and operates IT services for laboratory environments, including networks, compute, security, private cloud, and SDN platforms. Translates business and IT requirements into secure, standardized architectures and operational processes. Leads deployments, design reviews, documentation, incident gap analysis, automation, and infrastructure optimization. Requires extensive enterprise networking, datacenter, virtualization, Linux, security, and ITIL experience.

Designs and operates laboratory IT services covering compute, networks, security, private and public cloud, and software-defined networking. Translates business requirements into secure, high-performance service offerings; defines architectures, configurations, processes, and operational procedures. Leads implementations, design reviews, documentation, incident analysis, gap remediation, automation, and infrastructure optimization across global laboratory environments.

Lead an Automation Center of Excellence to build and maintain IaC, automation pipelines, and configuration management across colo and multi-cloud (Azure, GCP, OCI). Drive standardization, governance, security controls, CI/CD integration, incident management, GitOps and policy-as-code adoption. Mentor team members, manage vendor relationships, measure automation KPIs, and provide executive reporting. Participate in on-call rotation and work outside normal hours as needed.

The Senior IT Project Manager oversees the delivery of technology and business transformation projects, supports PMO standards, manages project risks, and mentors junior managers.

Lead mobile deployment teams for data center operations, ensuring effective execution, operational control, and client communication across various sites.

The M&A Lead Integration Architect will strategize and implement integration plans for acquired entities, collaborating with various teams to ensure seamless transitions and alignment with business goals.

Perform IT and integrated audits, document and test controls, support SOX and compliance activities, assist external auditors, provide remediation guidance, develop training, perform data analytics and system access reviews, and write audit reports for technical and non-technical audiences.

Manage sourcing strategy, contract lifecycle, and supplier relationships for enterprise software, SaaS, telecommunications, mobility, and IT services. Lead RFPs, negotiate licenses and renewals, optimize license use, manage telecom agreements, coordinate with IT/InfoSec/Legal, track savings and cost avoidance, and support Coupa-based P2P/CLM processes and supplier performance management.

Lead planning, execution, and delivery of enterprise technology projects. Manage scope, timelines, budgets, resources, risks, vendors, and stakeholder communications across Agile, Scrum, and Waterfall environments. Oversee software development, technology implementations, cloud transformation, application modernization, and other enterprise initiatives while coordinating cross-functional teams and multiple concurrent priorities.

Lead global IT operations for a HIPAA-regulated healthtech company, managing a small support team and hands-on ticketing. Build and maintain systems for compliance and visibility, optimize vendor costs, implement security/onboarding processes, drive process improvements with KPIs and automation, and serve as primary IT liaison to leadership and partners.

Lead strategic sourcing and category management for IT-related spend (software, hardware, cloud, telecom, cybersecurity, managed services). Partner with IT, Finance, Legal, and business stakeholders to conduct supplier/market analysis, negotiate contracts, implement supplier performance KPIs, mitigate risk, and optimize total cost and vendor value.

Drive national sales and account growth for IT cooling equipment, services, and software. Develop strategic customer relationships, pursue new business, manage channel partners, lead proposals and negotiations, forecast revenue, analyze market trends, and represent the company at industry events. The role requires technical knowledge of HVAC, mission-critical infrastructure, power quality, and data center solutions, along with strong commercial, communication, and relationship-management skills.

Provide frontline and advanced application support for radiology imaging workflows: incident triage, user provisioning, configuration changes, DICOM troubleshooting, monitoring interfaces, coordinating with networks/storage/vendors, maintaining SOPs and knowledge base, delivering end‑user training and on‑call doctor support to meet SLAs.

Designs and leads OneTrust Consent Management and Data Discovery architectures for life sciences clients. Integrates OneTrust with Salesforce, Veeva, Databricks, Snowflake, Azure, and AWS; creates ERDs, data dictionaries, and data flow diagrams; translates privacy requirements into technical designs; leads configuration with admins and developers; collaborates with legal, compliance, IT, and delivery teams; supports pre-sales workshops and client engagements. Requires approximately 10–20% travel.