Top Senior Machine Learning Jobs in Buffalo, NY

Seeking a Senior Full Stack .NET Developer to work on a social good project, with strong skills in C#, AngularJS, design, and UX. Requires 5+ years of experience.

Lead a multidisciplinary team to design, deploy, and optimize ML-driven bidding systems and measurement for a nine-figure marketing budget. Drive experimentation, partner strategy, media-mix optimization, and end-to-end measurement while aligning Marketing, Analytics, Engineering, and Product to improve marketing ROI and scale performance.

The Senior Data Scientist will design and deploy time-series forecasting models, collaborate with stakeholders, and operationalize models in cloud environments, focusing on demand planning across various industries.

Senior BI Data Researcher will lead research and engineering across modern data systems: big data management, data cleaning, quality, metadata, search/discovery, information extraction, time-series and heterogeneous analytics, applied AI/ML, distributed processing, and query/storage optimization. Collaborates with research teams to build scalable tooling, ML models across diverse modalities (tabular, time series, text, audio, video), and edge-enabled architectures.

Drive Midwest SLED revenue by selling analytics-driven SaaS identity and fraud solutions. Build pipeline, manage full sales cycle, develop partnerships/channels, collaborate with product, forecast accurately, and travel up to 50% to close deals and ensure customer success.

Lead product vision and execution for tDesign, an internal platform for small-molecule drug discovery. Define roadmap, translate complex AI/ML and scientific needs into intuitive UX, integrate AI agents and automated workflows, coordinate cross-functional teams, and drive adoption and product impact metrics.

The Engineering Manager will lead teams in developing and managing Blackbaud's Data & AI platform, focusing on scalability, security, and cost-efficiency.

Serve as the technical lead in pre-sales for state, local, and education customers: run discovery, design POCs and workshops, deliver demos, map needs to Socure solutions, advise on fraud/risk/compliance, influence product, and mentor junior consultants.

Lead end-to-end deployments of AI for hotel revenue teams: integrate PMS/CRS/RMS, ship ML/optimization models and agentic workflows, validate recommendations with revenue managers, define metrics, drive adoption, and hire/mentor the forward deployed engineering team.

Lead strategy, roadmap, and lifecycle for payer analytics and automation products. Translate market, customer, regulatory, and data insights into product requirements, drive cross-functional delivery with Engineering and Data Science, support go-to-market and adoption, and measure product performance to inform investment and portfolio decisions. Build product practices and partner with stakeholders across sales, customer success, clinical, actuarial, and executive teams.

Lead Growth Engineering architecture and implementation: build Go-based data pipelines, audit/replace martech, create experimentation infrastructure, ship full-stack Go/TypeScript features, productionize ML, review team work, and apply AI-assisted development daily.

Lead complex enterprise sales of AI-powered SaaS solutions, build pipeline, manage 6–12 month high-six-figure deals, multi-thread across stakeholder teams, collaborate with marketing/product/customer success, and translate technical AI capabilities into business ROI.

Lead execution of Product Engineering AI and automation initiatives across photonics products. Build and deploy reusable AI/automation tools, transform engineering data into AI-ready systems, and drive cross-functional adoption to improve development, qualification, manufacturing, and reliability processes.

Lead a consortium advancing AI-driven neurodegeneration research: set strategy, build partnerships, manage multidisciplinary executive team, oversee product development and deployment, secure funding, ensure ethical AI and scientific integrity, and scale the platform to broader biomedical domains.

Lead development of digital twin and simulation models for warehouse operations, deploy AI-driven decision systems, build forecasting and optimization models, validate experiments linking operational metrics to financial impact, and partner with engineers, operations, and external AI/academic partners to scale innovations across fulfillment networks.

The Business Development Director will lead strategic engagement with Google Cloud, focusing on partnership growth, go-to-market strategies, and revenue generation through cloud solutions.

Lead design and scaling of a unified fraud and risk platform. Own roadmap, fraud metrics, SQL-based analysis, A/B testing, real-time detection models, and cross-functional delivery to balance customer experience and risk mitigation.

Lead fraud detection and mitigation for a conversational BNPL product. Define fraud typologies, own repayment and chargeback analytics, manage fraud KPIs, design operational policies, collaborate on ML models and decisioning workflows, and coordinate SARs and compliance reporting.

Lead fraud detection and mitigation for a conversational Send Now Pay Later product: define first-party fraud typologies, own repayment and chargeback analytics, manage fraud KPIs, design operational policies, integrate ML and decisioning tools (Taktile), and coordinate SARs and compliance reporting.

Lead fraud detection and mitigation for a conversational BNPL product: define fraud typologies, analyze repayment/chargeback trends, own fraud KPIs, design policies, collaborate on ML models and decisioning workflows, and coordinate SARs with Compliance.

Lead fraud risk for a conversational lending product (SNPL): define first-party fraud typologies, analyze repayment and chargeback trends, own fraud KPIs, design automated/manual blocking policies, coordinate ML/rules with central Fraud and Data teams, and liaise with Compliance on SARs and loan abuse.

The AI Engineer will design and build production systems, focusing on LLM integration, system reliability, evaluation frameworks, and high-quality product features while maintaining strong engineering practices.

Lead end-to-end delivery of LOIS by owning the master program plan, coordinating cross-functional teams (engineering, product, design, ML, data, SRE, operations), resolving blockers and dependencies, establishing lightweight delivery infrastructure and tooling, partnering on release planning, and maintaining transparent status, risks, and accountability to deliver complex features to customers.

Drive new business and expand accounts by selling AI-driven services and software to engineering and manufacturing customers. Manage full sales cycle from prospecting to close, align solutions to measurable ROI, collaborate with technical and marketing teams, and meet revenue targets while attending industry events and maintaining CRM pipeline accuracy.

Design, optimize, and scale ClickUp's search infrastructure using OpenSearch/ElasticSearch. Improve relevance, speed, and real-time indexing; build vector/semantic search capabilities; create measurement frameworks; integrate search with AI and product features; troubleshoot at scale; and mentor junior engineers to maintain high search quality under heavy load.