Top Senior IT Jobs in St. Louis, MO

Architect, deploy, and support AWS-focused multi-cloud environments across AWS, Azure, and GCP. Manage Okta identity federation, certificates, DNS, networking, governance, security controls, and IaC-based CI/CD pipelines. Serve as a Tier 3 escalation point, validate cloud service delivery, document solutions, and partner with customers and internal engineering, cybersecurity, and operations teams. The role requires onsite or remote work with regular travel and an active Top Secret clearance.

Administers and supports PACS systems within an outpatient radiology practice, ensuring reliable technology operations, customer service, equipment use, policy compliance, and a safe work environment. The role may involve prolonged sitting, frequent standing and walking, and lifting up to 40 pounds. Employment requires successful drug and background screening.

Owns the architecture, configuration, integration, governance, and continuous improvement of inRiver, Bynder, and Boomi platforms. Integrates PIM, DAM, CRM, commerce, analytics, and ERP systems; develops and monitors Boomi processes; establishes master-data standards; leads technical projects, vendors, budgets, and delivery risks; and provides technical requirements, documentation, training, and executive communication.

Evaluates the design and operating effectiveness of IT application controls for Sarbanes-Oxley compliance. Responsibilities include developing test plans, testing automated controls and reports, reviewing system interfaces and data integrity, documenting audit workpapers, coordinating with external auditors, and recommending process improvements. The role collaborates with business and technology teams, supports SOX planning and execution, and may participate in cross-functional transformation projects.

Designs, installs, configures, maintains, and troubleshoots audiovisual systems including conferencing, digital signage, presentation, sound, and control systems. Manages AV network integration, upgrades, documentation, inventory, vendors, security compliance, and user training. Supports onsite and remote users, collaborates with IT teams, and recommends technology improvements. Requires occasional after-hours support, equipment handling up to 50 pounds, and work at heights.

Owns integrated delivery across four concurrent call orders within a large federal courts modernization program. Responsibilities include cross-program schedule, risk, dependency, governance, PI planning, executive reporting, contractual alignment, stakeholder communication, vendor coordination, and execution visibility. The role manages complex multi-vendor, SAFe-based delivery and supports capture and option-year planning. Remote work is available, with occasional travel and the ability to obtain a Public Trust determination required.

Administers Informix, MySQL, and other databases across cloud and hybrid environments. Responsibilities include configuration, maintenance, performance tuning, security remediation, replication, monitoring, Tier 3 support, schema changes, migrations, SQL data extraction, backup recovery testing, automation, compliance, and collaboration with engineering, architecture, security, and application teams.

Provides production database administration and support for mission-critical environments, including performance monitoring, incident response, root-cause analysis, security, and availability. Develops SQL Server database objects, ETL pipelines, dimensional models, data marts, dashboards, and Splunk monitoring solutions. Designs cloud and hybrid database architectures, performs data migrations, validates data integrity, and collaborates with stakeholders on technical requirements and analytics solutions within an Agile environment.

Leads Appen’s IT function, including support, enterprise technology, security governance, automation, vendor management and team development. Owns the IT roadmap, Microsoft 365 and SaaS environment, endpoint and identity controls, SOC 2 and ISO 27001 readiness, technology spend, and AI-enabled process improvement. Partners with executives, Engineering and Product to improve service delivery, eliminate manual work, manage risk and build a scalable, high-performing IT organization.

Provides second-line remote IT support for client end users, resolving escalated Windows, macOS, Microsoft 365, identity, Intune, application, printing, and collaboration issues. Manages onboarding, offboarding, access changes, endpoint deployment, patching, and security compliance. Works within ticket priorities and service-level objectives, documents solutions, creates knowledge articles, identifies recurring problems, and escalates infrastructure issues with detailed troubleshooting information.

Leads large-scale Oracle Cloud Infrastructure migration programs, managing schedules, budgets, risks, dependencies, governance, vendors, stakeholders, and cloud delivery teams. Oversees migration planning and execution for applications, databases, and infrastructure; drives change management, documentation, training, compliance, cost optimization, quality, and operational reporting. The role also supports cloud adoption, partner coordination, and predictable cutovers across multiple initiatives.

Supervises policy and legal affairs contractors while drafting, editing, researching, and reviewing policies, procedures, reports, responses, and executive materials. Coordinates approval processes, FOIA and congressional inquiry responses, interagency reviews, stakeholder communications, document management, and special projects. Oversees staff performance, onboarding, training, deliverables, timecards, reports, and process improvements. Supports research involving child welfare, foster care, mental health, family reunification, and underserved populations.

Leads the design, implementation, administration, integration, testing, and enhancement of Veeva Vault RIM. Translates business requirements into functional specifications, manages application roadmaps, supports GxP compliance, oversees internal and external technical resources, and drives system optimization. The role also provides troubleshooting, root-cause analysis, user support, data migration assistance for M&A activities, and technology guidance involving emerging technologies and AI.

Supports governance, monitoring, and IT General Controls for third-party relationships and external users. Responsibilities include due diligence, risk classification, identity and access oversight, least-privilege reviews, access certifications, MFA and DLP monitoring, incident escalation, remediation tracking, audit support, reporting, business continuity and disaster recovery activities, offboarding controls, process documentation, and stakeholder coordination across IT, security, compliance, legal, HR, and vendor management.

Develops and enhances Oracle EBS asset, financial, and logistics modules for Defense Logistics Agency programs. Builds integrations, RICE-FW interfaces, conversions, reports, and automation for capitalization, depreciation, valuation, and accounting processes. Supports testing, troubleshooting, reconciliation, audit traceability, technical documentation, and data mapping. Collaborates with functional SMEs on A2R requirements and process flows while integrating Oracle EBS with external asset and logistics systems.

Leads enterprise IT infrastructure and service operations, overseeing service-level performance, ITSM processes, project intake, business requirements, reporting, budgets, process improvement, escalations, and stakeholder relationships. Develops service delivery plans, manages providers and SLAs, supports healthcare and Medicaid contract compliance, and guides cross-functional initiatives. Hires, mentors, and develops a high-performing IT team while ensuring reliable services, operational efficiency, and alignment with organizational goals.

Supervises monitoring and compliance staff conducting grant-program reviews. Provides technical guidance, coordinates monitoring schedules and site assessments, reviews reports and corrective actions, analyzes compliance trends and risks, and recommends improvements. Oversees staff performance, training, deliverables, timecards, and reporting. Leads on-site and remote reviews, interviews stakeholders, evaluates program data and documentation, identifies technical assistance needs, and communicates findings to federal and recipient staff. Requires frequent domestic travel despite being fully remote.

Provides production support and administration for mission-critical databases, including monitoring, incident response, root-cause analysis, performance optimization, and on-call coverage. Develops SQL database objects, Databricks lakehouse models, ETL pipelines, data migrations, dashboards, and data governance standards. Collaborates with stakeholders and development teams in an Agile environment while ensuring data integrity, scalability, security, and availability across AWS and hybrid-cloud platforms.

Supports a federal agency Regional Representative by monitoring grantee programs, reviewing financial and performance data, conducting site visits, analyzing compliance and program gaps, and preparing findings and recommendations. Provides technical assistance, supports grants management and regional initiatives, collaborates with government and community stakeholders, and performs research and functional analysis for federal decision-making.

Leads IT audit engagements by assessing technology and business-process risks, testing IT controls for SOX and regulatory compliance, documenting workpapers, and presenting findings and recommendations. Supports enterprise risk assessments, updates audit programs and policies, prepares control reports, and contributes to team development. The role requires strong communication, project management, IT governance knowledge, and experience with audit frameworks and financial services environments.

Own day-to-day IT operations, service management, endpoint security, identity and access administration, cloud infrastructure support, vendor and MSP oversight, business-unit technology integrations, and SOC 2 or other audit readiness. The role manages Microsoft 365, Google Workspace, AWS, Azure, endpoint tools, security platforms, device compliance, operational documentation, procurement, and technical evidence across multiple business units.

Develop and maintain agency-wide PaaS capabilities across cloud and datacenter environments. Manage Red Hat OpenShift clusters, operators, GitOps frameworks, and platform deployments across multiple security domains. Scale platforms, support data services, coordinate integrations, maintain security compliance, deploy new sites, and produce technical documentation. The role requires TS/SCI clearance, a technical bachelor’s degree, 5–8 years of experience, and DoW 8570 IAT Level II certification.

Monitors government-funded care programs through on-site visits, provider interviews, documentation reviews, inventory assessments, and compliance evaluations. Identifies technical assistance needs, evaluates service quality and individual safety, conducts entrance and exit meetings, prepares monitoring reports, maintains records, and advises providers on child welfare best practices and corrective actions. The role is fully remote with frequent domestic travel to designated provider sites.

Supports IT procurement, purchasing, vendor management, third-party risk, privacy, compliance, audit readiness, and governance activities. Responsibilities include RFPs and vendor evaluation, purchase orders and invoice reconciliation, vendor due diligence, contract compliance, policy administration, remediation tracking, business continuity and disaster recovery governance, privacy documentation, reporting, and process improvement. The role also provides guidance to less experienced team members and partners with IT Security, Legal, Privacy, Finance, auditors, vendors, and business teams.

Leads complex, cross-regional IT programs from business case through deployment and stabilization, with emphasis on SAP implementations and transformations. Establishes governance, plans, budgets, risk controls, dependencies, and executive reporting. Coordinates business, technical, data, testing, integration, and deployment teams while managing consulting partners, systems integrators, and vendors. Also supports recovery planning, portfolio prioritization, PMO standards, and coaching of project managers.