Top Senior Data Science Jobs in St. Louis, MO

This role involves applying advanced data science and machine learning methods to healthcare data, leading teams, managing client relations, and developing analytics products for payers, while mentoring junior staff.

As a Staff Data Scientist at SentiLink, you will develop fraud detection models, conduct analyses, collaborate across teams, and drive the development of financial risk products.

Lead end-to-end data science projects, develop machine learning models, collaborate with stakeholders, mentor team members, and communicate insights effectively.

Design and train LLMs and agentic systems for cybersecurity using RLHF/RLAIF and supervised fine-tuning. Build agent architectures, tooling, retrieval/memory, and evaluation pipelines with rigorous statistical benchmarking. Optimize prompts and inference, collaborate with engineers to productionize prototypes, and drive research on agent planning, safety, and reliability.

Lead product analytics to inform strategy and optimize user experience: translate business questions into analysis, build reliable analytics infrastructure, run A/B tests and ML/statistical analyses, track funnels and cohorts, support 0-to-1 product launches, and communicate actionable insights to cross-functional teams.

Design, refine, and operationalize geospatial analytic models to bring structure and defensibility to GEOINT. Extract, transform, and structure complex datasets using Python and SQL, integrate models with ArcGIS, automate workflows, build dashboards, and ensure GEOINT tradecraft integrity and transparency in scoring frameworks.

Lead design and delivery of advanced analytics, AI/ML models, automation, and custom visualizations using Esri and Python tools to support Intelligence Community missions. Build pipelines, mentor team members, conduct peer reviews, translate customer requirements into technical solutions, and present findings to stakeholders.

Design, refine, and operationalize geospatial analytic models; structure GEOINT attributes into defensible scoring frameworks; automate workflows and build dashboards; integrate models with analytic platforms (ArcGIS); work with analysts and leadership to ensure tradecraft integrity, transparency, and repeatable mission-focused outputs using Python and SQL.

As a Senior Data Scientist, you will lead high-complexity projects, develop ML and NLP solutions, and collaborate across teams to drive business impact through statistical modeling and data analysis.

Lead and deliver end-to-end data science projects: design, build, deploy, and monitor ML/statistical models for credit risk, pricing, collections, and fraud. Partner with cross-functional teams to integrate models into production, set model development standards, mentor engineers, and maintain reliable ML pipelines and monitoring systems.

Lead development and deployment of predictive models, analytics, and dashboards to support Sales, Marketing, Customer Success, and GTM operations. Mentor data scientists, partner with business leaders to prioritize analytics, ensure data governance and quality, and present insights to executives. Work with Snowflake/data lakes, build scalable ML solutions, and drive analytics adoption across the enterprise.

Lead data science initiatives to develop and deploy AI solutions that improve business outcomes. Collaborate with cross-functional teams to analyze data, create models, and evaluate performance.

Build and deploy predictive and time-series models using HR and clinical data (Oracle HCM, GCP) to forecast staffing, identify flight-risk employees, analyze pay/burnout relationships, and create interactive dashboards and analyses to inform HR strategy and operational workforce decisions.

Design, build, and deploy machine learning and generative AI models (including LLMs and text-to-image). Analyze large datasets, run A/B and statistical tests, collaborate with data engineering and engineering teams, and create dashboards/visualizations to communicate insights. Optimize data pipelines and model performance to support data-driven decisions.

Build and scale production-ready generative AI applications: design multi-agent workflows, implement advanced RAG with vector DBs, integrate/swap LLMs, fine-tune models, and deploy scalable FastAPI/Docker services with monitoring and optimization for latency, cost, and reliability.

Design, build, and deploy production-ready generative AI applications: architect multi-agent workflows, implement advanced RAG with vector DBs, integrate/swap LLMs, fine-tune models, and deliver scalable FastAPI-based services with monitoring, CI/CD, and containerized deployment.

Build and scale production Generative AI applications: design multi-agent systems and LangGraph workflows, implement advanced RAG with vector DBs, integrate and fine-tune LLMs, deploy FastAPI async services in Docker, and optimize GenAI performance, cost, and monitoring.

The Senior Data Scientist will build models and analyses, design experiments, integrate datasets, and leverage AI for improved workflows and insights in data science.

The Data Scientist will create and deliver analytic processes and data solutions while coordinating with clients to address data-related issues. Responsibilities include designing data architecture, building ETL pipelines, integrating APIs, conducting impact analysis, and preprocessing geospatial data.

The Data Scientist II will drive insights, develop models, and analyze product experiments to inform business decisions and improve member experiences in healthcare.

Designs, analyzes, and interprets clinical trial, RWE, and observational data for a medical device. Develops statistical plans, predictive models, and ensures data quality, regulatory compliance, and traceability. Collaborates with clinical, regulatory, and data teams, supports submissions and publications, mentors interns, and represents the company externally.

Lead design and deployment of deep learning and predictive models, mentor data teams, author architecture decisions, collaborate with product and engineering, implement CI/CD and MLOps best practices, and translate ambiguous business problems into high-impact data solutions for multi-unit hospitality customers.

Seeking a skilled Data Scientist/Machine Learning Engineer to develop machine learning models, design AI systems, and collaborate in data analytics. Responsibilities include productionizing models, data engineering, and cross-functional collaboration.

The Senior Applied AI Data Scientist will build AI workflows, prototype applications, and enhance decision-support systems while collaborating with various teams to operationalize AI solutions.

As a Staff Data Scientist, you will analyze large-scale broadband data, develop and validate ML models, and integrate solutions into Calix Cloud, collaborating with teams for enhanced network intelligence and subscriber experience.