Top Senior Data Science Jobs in St. Louis, MO

Leads teams in designing and deploying scalable AI and machine learning solutions for consulting clients. Responsibilities include data wrangling, complex analysis, data modeling, AI system implementation, data pipeline and infrastructure oversight, deep learning, neural networks, data quality validation, and stakeholder collaboration. The manager coaches team members, manages performance, supports innovation, and applies Python, Java, and cloud technologies to build production-ready AI applications.

Own the reliability and quality of an AI copilot for trading platforms. Build evaluation frameworks, benchmarks, quality gates, monitoring, incident response, and model improvement loops. Partner with engineering and product on safe tool interactions, auditability, and user trust. Develop trading-domain expertise and measurement systems covering correctness, safety, latency, regression risk, and workflow performance.

Lead complex modeling projects combining deep learning, LLMs, and traditional techniques. Prototype, deploy, and monitor production models, mentor data scientists, collaborate with engineering/product, and translate results into business impact for insurance customers.

Leads payer healthcare data science and operations consulting initiatives, using business analytics to improve payer processes and performance. Manages teams, client relationships, project resources, strategic planning, process optimization, quality standards, and operational transformation. Coaches junior staff, promotes innovative technologies, and identifies opportunities to enhance operational excellence and business outcomes.

Provides strategic and technical leadership for advanced credit-risk data science. Owns the multi-year modeling roadmap and independently develops, implements, validates, monitors, and improves machine learning models for credit acquisition, underwriting, portfolio management, and customer risk. Applies advanced statistical and ML techniques, conducts fair-lending and explainability analyses, researches emerging methods, and communicates modeling strategy and results to executive and cross-functional stakeholders.

Develop predictive, prescriptive, forecasting, valuation, and portfolio-performance models supporting collections, acquisitions, and business strategy. Build production data pipelines, transformations, analytical workflows, data models, quality checks, and monitoring frameworks using SQL, Python, and/or R. Perform exploratory analysis, create dashboards and reports, translate business needs into technical solutions, and collaborate with analytics, engineering, and business stakeholders.

Lead the design, development, deployment, monitoring, and improvement of interconnected customer lifetime value models covering conversion, retention, premiums, and claim losses. Serve as a hands-on technical leader, guide modeling strategy, evaluate experiments and business impact, partner with engineering and business teams, support production ML systems, establish technical standards, and coach other data scientists.

Develop data pipelines, organize and analyze structured and unstructured government data, create visualizations, build AI agents and lightweight automations, and occasionally develop predictive models. The role involves consulting with senior stakeholders, communicating actionable insights, supporting data capacity building, and collaborating with product, design, engineering, and research teams in a remote government-services environment.

Own the reliability and quality of an AI copilot for a trading platform. Build evaluation frameworks, benchmarks, quality gates, monitoring, incident response, and model improvement workflows. Partner with engineering and product to create safe, auditable tool interactions and improve assistant behavior. Develop domain expertise in trading, risk, margin, execution, and portfolio reasoning while operating across model, backend, and frontend systems.

Develop machine learning and statistical models to identify, measure, and manage credit and fraud risk. Partner with stakeholders to translate requirements into scalable solutions, analyze large application and transaction datasets, deploy end-to-end models, and improve risk decision-making. The role requires advanced Python or R and SQL skills, expertise in fraud and underwriting models, model deployment, statistical methods, and mentoring junior data scientists.

The Data Scientist will transform real-world, clinical, and preclinical healthcare data into reproducible datasets, analyses, and evidence supporting medical-device research and regulatory needs. Responsibilities include cohort development, data-quality validation, statistical programming, study design support, analysis plans, clinical and post-market analyses, documentation, and communicating findings to technical and nontechnical stakeholders. The role collaborates with Scientific, Clinical, R&D, Regulatory, Quality, IT, and external data partners.

Develop and implement data science strategies for machine learning applications including lead scoring, churn modeling, pricing, personalization, and fraud detection. Own end-to-end initiatives spanning data analysis, feature engineering, model training, inference, and monitoring. Collaborate with engineering, infrastructure, analytics, and business teams to deliver measurable impact, improve data capabilities, and communicate findings to technical and non-technical stakeholders.

Develop, train, evaluate, deploy, and monitor machine learning and statistical models using Databricks, Python, SQL, Spark, Delta Lake, and MLflow. Prepare datasets, engineer features, manage model lifecycles, validate data, and support governance practices. Translate client requirements into scalable analytics solutions, analyze trends, and communicate findings to technical and non-technical stakeholders while collaborating across data science, engineering, cloud, security, and business teams.

Drive product and business impact through statistical modeling, experiment design, Bayesian marketing analysis, machine learning, NLP, LLM applications, and classifier implementation. Build growth metrics, monitoring pipelines, evaluation datasets, and AI trigger systems across search and Duck.ai. Analyze privacy-constrained data, deploy production-grade models, optimize SQL queries, and lead complex projects from scoping through production with minimal direction.

Lead the development of statistical and machine learning models for time-series and geospatial data. Build analytic solutions, datasets, ETL workflows, forecasting and anomaly-detection models, simulations, visualizations, and reports. Evaluate algorithm performance, optimize classifiers, document processes, and collaborate with engineers, analysts, mission partners, and stakeholders to deliver reliable mission-focused software and data capabilities.

Lead statistical and machine learning model development for time-series and geospatial data supporting the FALCON mission. Responsibilities include feature engineering, forecasting, anomaly detection, ETL, dataset creation, algorithm evaluation, simulation, data visualization, reporting, documentation, and stakeholder collaboration. The role also contributes to software applications, APIs, data pipelines, code reviews, troubleshooting, and iterative agile development.

Lead a small data science team while remaining hands-on in building advertising audience, measurement, ranking, and data-feed models. Set technical direction, apply causal inference and experimental design, build scalable production systems, mentor scientists, and partner with product, engineering, sales, and business development teams. Translate campaign data into trusted measurement products, influence senior leaders and customers, and establish Fetch’s methodology as a market standard.

Develop marketing effectiveness analytics using Marketing Mix Modeling, attribution, customer lifetime value, experimentation, and causal inference. Build automated, scalable model pipelines, insight-ready datasets, and self-serve dashboards. Analyze campaigns, support marketing strategy, communicate findings to executives, and lead high-impact projects independently while collaborating cross-functionally.

Own analytical strategy and develop AI/ML models for Zip’s financial products, including cash and rent advances. Lead ambiguous 0-to-1 initiatives using bank transaction data, establish evaluation frameworks, guide risk and growth decisions, and deliver models from experimentation through production. Provide technical direction to data scientists, mentor junior team members, collaborate with engineering, and advise senior stakeholders on model trade-offs. The role requires strong financial services, statistical, research, and machine learning expertise.

Own product-led growth analytics across activation, engagement, conversion, monetization, and retention. Lead experimentation, statistical analysis, causal inference, metric development, and proactive opportunity discovery. Build scalable analytical systems, monitoring frameworks, semantic models, and AI-powered tools. Partner with Product, Engineering, and leadership to shape product bets, investment decisions, and roadmap priorities. Work autonomously in a remote-first environment and communicate complex findings through clear, actionable recommendations.

Lead computational platform development for biological design, optimization, and functional prediction. Collaborate with wet-lab scientists to validate predictions, oversee data infrastructure and computational workflows, and contribute to technology roadmaps, funding proposals, and partnerships. The role requires developing machine learning methods for biological sequence and structure analysis, translating biological problems into computational solutions, and leading technical teams across computational and experimental disciplines.

Build and deploy machine learning models that personalize insurance products, analyze product data, design experiments, and measure model impact. The role owns the full data science lifecycle, including data wrangling, production coding, model monitoring, retraining, and experimentation. Responsibilities also include cross-functional collaboration, code reviews, mentoring data scientists, and improving platform practices.

Build and evaluate machine learning models and features for fraud detection across account opening, account takeover, and identity risk. Investigate fraud patterns, analyze complex datasets, develop production-ready code, validate models, and support monitoring and deployment. Collaborate with senior data scientists, engineers, and score monitoring teams while communicating findings to technical and nontechnical audiences. Apply data privacy, explainability, documentation, validation, and governance standards.

Own data science for customer-facing product features, including LTV prediction, experimentation, benchmarking, and forecasting. Proactively analyze data to identify customer problems and product opportunities, build and deploy production-grade models, and influence product roadmaps. Partner with Product, Engineering, and Analytics, communicate findings to varied audiences, iterate on shipped features, and lead new data-driven initiatives.

Design and architect secure, scalable healthcare data systems; create core data models using TUVA, OMOP, and FHIR; build production data pipelines and EMR integrations; establish data quality and governance; optimize performance; deploy cloud infrastructure; and ensure HIPAA and HITRUST compliance. The role requires expert SQL and Python or Scala skills, advanced data warehouse and big-data experience, and at least eight years in data science or data engineering.