Top Senior Data Science Jobs in St. Louis, MO

Leads teams in designing and deploying scalable AI and machine learning solutions for consulting clients. Responsibilities include data wrangling, complex analysis, data modeling, AI system implementation, data pipeline and infrastructure oversight, deep learning, neural networks, data quality validation, and stakeholder collaboration. The manager coaches team members, manages performance, supports innovation, and applies Python, Java, and cloud technologies to build production-ready AI applications.

Lead the development of statistical and machine learning models for time-series and geospatial data. Build analytic solutions, datasets, ETL workflows, forecasting and anomaly-detection models, simulations, visualizations, and reports. Evaluate algorithm performance, optimize classifiers, document processes, and collaborate with engineers, analysts, mission partners, and stakeholders to deliver reliable mission-focused software and data capabilities.

Lead statistical and machine learning model development for time-series and geospatial data supporting the FALCON mission. Responsibilities include feature engineering, forecasting, anomaly detection, ETL, dataset creation, algorithm evaluation, simulation, data visualization, reporting, documentation, and stakeholder collaboration. The role also contributes to software applications, APIs, data pipelines, code reviews, troubleshooting, and iterative agile development.

Design, build, and deploy machine learning solutions in distributed systems; collaborate with engineers and subject-matter experts; evaluate and improve models; ensure data security and compliance; communicate insights to stakeholders; mentor junior data scientists.

Leads data science and exploitation activities supporting NGA GEOINT operations. Analyzes large structured and unstructured datasets, develops automated workflows and analytic applications, applies AI/ML and advanced statistical methods, creates customized visualizations, and supports data management and modernization initiatives. The role serves as a technical SME, collaborates with stakeholders and product owners, conducts peer reviews, and mentors team members. Requires extensive data science experience, Esri expertise, and an active TS/SCI clearance.

Lead development of statistical and machine learning models for time-series, geospatial, kinematic, and radar data. Build analytic solutions, training datasets, ETL workflows, forecasting and anomaly-detection models, simulations, visualizations, and performance metrics. Integrate multi-source sensor data, enhance algorithms, document processes, and collaborate with engineers, analysts, mission partners, and stakeholders in an agile environment.

Lead design and delivery of scalable ML systems across the full lifecycle for recommendations, demand forecasting, targeting, and personalization. Collaborate with engineers, product, and stakeholders to set architecture, metrics, and production best practices; mentor data scientists; lead experimentation and deploy/monitor models using cloud and MLOps tooling.

Lead data science efforts for a defense program onsite in Hazelwood, MO. Define data requirements, build analysis systems, design/deploy ML models, collaborate with engineers and SMEs, mentor junior scientists, ensure security/compliance, and communicate results to stakeholders while improving models and establishing best practices.

Lead complex modeling projects combining deep learning, LLMs, and traditional techniques. Prototype, deploy, and monitor production models, mentor data scientists, collaborate with engineering/product, and translate results into business impact for insurance customers.

Lead end-to-end pricing experimentation and strategy for consumer and business products. Design and analyze A/B tests, build pricing models and production-grade data pipelines, partner cross-functionally, and present actionable recommendations to senior leadership.

Design and deploy optimization and machine learning models for allocating scarce parts and resources across competing programs. Responsibilities include formulating MILP and constraint optimization models, forecasting demand and supply risk, building data pipelines, validating outputs, communicating tradeoffs to stakeholders, mentoring junior data scientists, and partnering with software engineers to productionize scalable services.

Lead research and engineering of production-grade LLM/GenAI systems for cybersecurity: design models and architectures, drive data labeling and evaluation, collaborate with product and engineering to deploy scalable solutions, mentor data scientists, set technical strategy, and advance AI safety, red-teaming, and applied ML innovations for detection and operational use.

Lead performance marketing data science initiatives focused on lead segmentation, bidding optimization, targeting, and marketing spend allocation. Develop and deploy production-ready machine learning systems, establish research and ML operations roadmaps, build monitoring frameworks, and identify high-impact opportunities. Partner with engineering, marketing, vendors, and executives while mentoring data scientists and machine learning engineers and promoting rigorous, maintainable, and reproducible practices.

Leads data science and advanced analytics initiatives for Auto Claims by developing, evaluating, and implementing machine learning and predictive modeling solutions. Integrates structured and unstructured data, researches emerging techniques, communicates model results to stakeholders, and manages moderately complex projects. Provides initial mentoring and development support to junior data scientists while helping improve business decisions and outcomes.

Leads advanced analytics, machine learning, statistical modeling, and NLP solution development using healthcare and operational data. Builds scalable pipelines, visualizations, and deployed models on Google Cloud Platform, translates findings for clinical and executive leaders, designs experiments, and establishes performance metrics. Requires collaboration across clinical, technical, and data engineering teams, with occasional on-site travel for executive presentations.

Lead data science for Mozilla’s advertising business by identifying high-impact opportunities, owning complex analyses, developing measurement and experimentation frameworks, analyzing revenue and performance, and translating findings into recommendations for technical partners and executives. Partner across Product, Engineering, Sales, Finance, and leadership to support business decisions in a fast-moving environment while balancing analytical rigor, pragmatism, and user privacy.

Lead data science partnership for Mozilla’s advertising business, identifying high-impact opportunities and owning complex analytics end to end. Develop measurement frameworks, experimentation strategies, instrumentation, and reporting for advertising products. Analyze revenue and performance, evaluate trade-offs, and communicate clear recommendations and uncertainty to technical teams and senior executives.

Lead the design and optimization of the VA VHA AI Education Hub, including its AI learning assistant, sandbox, integrations, analytics, and healthcare data models. Apply machine learning, synthetic data, privacy-preserving methods, and responsible AI practices in a secure federal healthcare environment. Collaborate with VA stakeholders and technical teams, document solutions, ensure governance and compliance, and present platform metrics and findings to leadership.

As a Staff Data Scientist at SentiLink, you will develop fraud detection models, conduct analyses, collaborate across teams, and drive the development of financial risk products.

Staff Data Scientist responsible for owning ambiguous, high-impact product and business problems; designing experiments; analyzing product data; developing analytical tools and frameworks; partnering with product, engineering, design, and leadership; and mentoring data scientists. The role requires advanced statistical expertise, strong product judgment, production programming experience, and the ability to translate complex analyses into strategic recommendations.

Conduct workforce analytics and applied organizational research on attrition, mobility, engagement, performance, and planning. Analyze and validate HR data using SQL, R, or Python; apply statistical testing and regression; translate business questions into actionable insights; and communicate findings through visualizations, reports, and presentations. Partner with HR stakeholders while maintaining the accuracy, documentation, confidentiality, and integrity of sensitive workforce data.

Lead product analytics efforts by designing and evaluating experiments, building dashboards, and producing statistical insights. Partner with product, design, and engineering to measure product success, identify optimization opportunities, and embed ML-driven personalization into the product.

Build and productionize traditional machine learning models, owning feature engineering, validation, deployment, monitoring, drift detection, and retraining. Develop LLM-powered agentic tools, dashboards, self-serve analytics products, and automated insight pipelines. Partner with engineering and business stakeholders, write production-grade Python and SQL, drive adoption, improve data quality, and establish responsible AI workflows for a regulated industry.

Leads analytical and scientific strategy for Fetch’s Play and Rewarded Apps businesses. Develops predictive and machine learning models, experimentation frameworks, causal analyses, feature pipelines, and measurement systems using Python and SQL. Partners with Product, Marketing, Engineering, and business leaders to improve monetization, engagement, retention, personalization, and marketplace outcomes. Translates complex findings into strategic recommendations, mentors data scientists and analysts, and establishes analytical best practices.

Design, deploy, and manage machine learning models supporting client acquisition, retention, and reactivation. Develop Next Best Action, CRM, paid media, and personalization solutions using LLMs and traditional ML. Design and interpret experiments, analyze large-scale datasets, communicate recommendations to stakeholders, and collaborate with product, design, and engineering teams on product and infrastructure roadmaps.