Top Senior Data Science Jobs in St. Louis, MO

Leads payer healthcare data science and operations consulting initiatives, using business analytics to improve payer processes and performance. Manages teams, client relationships, project resources, strategic planning, process optimization, quality standards, and operational transformation. Coaches junior staff, promotes innovative technologies, and identifies opportunities to enhance operational excellence and business outcomes.

Design, build, and deploy machine learning solutions in distributed systems; collaborate with engineers and subject-matter experts; evaluate and improve models; ensure data security and compliance; communicate insights to stakeholders; mentor junior data scientists.

Own the reliability and quality of an AI copilot for a trading platform. Build evaluation frameworks, benchmarks, quality gates, monitoring, incident response, and model improvement workflows. Partner with engineering and product to create safe, auditable tool interactions and improve assistant behavior. Develop domain expertise in trading, risk, margin, execution, and portfolio reasoning while operating across model, backend, and frontend systems.

Leads teams in designing and deploying scalable AI and machine learning solutions for consulting clients. Responsibilities include data wrangling, complex analysis, data modeling, AI system implementation, data pipeline and infrastructure oversight, deep learning, neural networks, data quality validation, and stakeholder collaboration. The manager coaches team members, manages performance, supports innovation, and applies Python, Java, and cloud technologies to build production-ready AI applications.

Own product analytics for a healthcare platform by translating business questions into research plans, uncovering insights, modeling feature impacts, defining success criteria, and leading A/B testing. Partner with Product, Data Engineering, Finance, Clinical, and Operations teams to influence roadmap decisions, improve provider experience and quality, and optimize marketplace performance.

Lead the development of statistical and machine learning models for time-series and geospatial data. Build analytic solutions, datasets, ETL workflows, forecasting and anomaly-detection models, simulations, visualizations, and reports. Evaluate algorithm performance, optimize classifiers, document processes, and collaborate with engineers, analysts, mission partners, and stakeholders to deliver reliable mission-focused software and data capabilities.

Lead statistical and machine learning model development for time-series and geospatial data supporting the FALCON mission. Responsibilities include feature engineering, forecasting, anomaly detection, ETL, dataset creation, algorithm evaluation, simulation, data visualization, reporting, documentation, and stakeholder collaboration. The role also contributes to software applications, APIs, data pipelines, code reviews, troubleshooting, and iterative agile development.

Lead data science efforts for a defense program onsite in Hazelwood, MO. Define data requirements, build analysis systems, design/deploy ML models, collaborate with engineers and SMEs, mentor junior scientists, ensure security/compliance, and communicate results to stakeholders while improving models and establishing best practices.

Develops and deploys analytical and machine learning solutions, leading exploratory data analysis, statistical modeling, feature engineering, scalable data pipelines, validation frameworks, and model optimization. Collaborates with product and engineering teams on proofs of concept and production integration, evaluates emerging technologies, and communicates insights through visualizations and presentations. Requires Python, SQL, cloud or containerized environments, ML pipeline experience, U.S. citizenship, and the ability to obtain and maintain Public Trust clearance.

Lead and build Neural Earth's geospatial data science function: design and deploy Python-based geospatial models, architect production geospatial data pipelines, validate reproducible methods, translate scientific outputs into customer-ready products, and manage and mentor at least one direct report while advising customers and stakeholders.

Own product-led growth analytics across activation, engagement, conversion, monetization, and retention. Lead experimentation, statistical analysis, causal inference, metric development, and proactive opportunity discovery. Build scalable analytical systems, monitoring frameworks, semantic models, and AI-powered tools. Partner with Product, Engineering, and leadership to shape product bets, investment decisions, and roadmap priorities. Work autonomously in a remote-first environment and communicate complex findings through clear, actionable recommendations.

Develops predictive models and transforms structured and unstructured data into actionable insights. Responsibilities include data wrangling, statistical analysis, machine learning, visualization, reporting, data pipeline management, cloud and DevSecOps integration, root-cause analysis, and technical solution development. The role supports government stakeholders, guides junior personnel, leads data projects independently, validates AI models, documents algorithms, and communicates findings through briefings and presentations.

Manage NASA aerospace portfolio data through cataloging, metadata standards, taxonomies, controlled vocabularies, data lineage, provenance, classification, and quality documentation. Evaluate and implement an enterprise data catalog, integrate it with Dagster, establish metadata and freshness metrics, onboard and retire datasets, and drive adoption across technical and program teams. Translate between data professionals and program stakeholders while improving data discoverability, trust, and usability.

Lead the design, development, deployment, monitoring, and improvement of interconnected customer lifetime value models covering conversion, retention, premiums, and claim losses. Serve as a hands-on technical leader, guide modeling strategy, evaluate experiments and business impact, partner with engineering and business teams, support production ML systems, establish technical standards, and coach other data scientists.

Leads development of statistical and machine learning models for time-series, geospatial, kinematic, and radar data. Responsibilities include feature engineering, forecasting, anomaly detection, data integration, ETL, visualization, algorithm evaluation, simulation, dataset creation, and stakeholder communication. The role also contributes to mission-focused software applications, APIs, data pipelines, documentation, code reviews, and agile development while requiring an active Top Secret or CBP/DHS suitability clearance.

Set the technical vision for data science, lead complex statistical and machine learning model development from concept through production, and architect scalable modeling platforms and pipelines. Develop credit risk, pricing, and loss forecasting models; establish model governance standards; partner with senior leaders; mentor data scientists; and communicate technical strategy to executives. The role emphasizes production deployment, monitoring, cloud architecture, and high-impact decision-making across the business.

Analyzes financial and ERP data using statistical analysis, data mining, predictive modeling, and advanced algorithms. Supports Oracle financial shared services, data conversion, business continuity, disaster recovery, and contingency planning. Develops analytical outputs that improve agency KPIs and identifies trends and business opportunities. Requires collaboration with systems, network, hosting, and disaster recovery teams, plus participation in COOP exercises and Oracle environment upgrades.

Develop machine learning, AI, statistical, and predictive models using Snowflake and other data sources. Perform data extraction, cleansing, feature engineering, experimentation, visualization, and quality analysis. Partner with business and technical teams to deliver data products, conversational analytics, and actionable recommendations. Lead discovery sessions, communicate insights to nontechnical audiences, mentor analysts, and support enterprise data science projects.

Serve as Netflix Animation Studios’ founding data scientist, developing measurement frameworks, forecasting and scenario-planning models, dashboards, and data products for slate planning, production efficiency, workforce allocation, and strategic decision-making. Partner with studio leadership, data scientists, analytics engineers, and data engineers to establish data foundations, define metrics, analyze operational drivers, and translate complex findings into actionable recommendations.

Leads advanced data science and machine learning initiatives for healthcare payment integrity, including fraud, waste, and abuse detection, anomaly identification, predictive modeling, statistical analysis, dashboards, and recovery investigations. Provides technical leadership, mentors analysts, integrates production analytical solutions, collaborates with legal and business stakeholders, and presents findings to leadership. Requires healthcare expertise, advanced SQL and programming skills, and knowledge of claims, billing, reimbursement, and program integrity.

Develop and deploy enterprise machine learning and data science solutions across the full lifecycle. Responsibilities include statistical analysis, predictive modeling, feature engineering, data exploration, model deployment and monitoring, MLOps, ETL, and business intelligence reporting. The role collaborates with engineers, product managers, stakeholders, and cross-functional teams to deliver scalable solutions using cloud platforms, large-scale data, and modern machine learning technologies.

Build Boulevard’s Product Intelligence function by developing product data foundations, pipelines, dashboards, experimentation practices, and customer behavior models. Partner with Product, Engineering, and leadership to deliver actionable insights, self-serve analytics, and productionized models. Establish scalable processes, instrumentation standards, statistical workflows, and data-driven decision-making across the organization.

Partner with clients to design healthcare data science solutions, curate multimodal clinical datasets, and conduct statistical, predictive, causal inference, real-world evidence, and AI/ML analyses. Responsibilities include querying EMR and other health data sources, creating statistical analysis plans, managing SQL and analytical programming, ensuring HIPAA-compliant data quality, documenting findings, and presenting results to technical, clinical, and executive audiences.

Lead development of statistical and machine learning models for time-series, geospatial, kinematic, and radar data. Build analytic solutions, training datasets, ETL workflows, forecasting and anomaly-detection models, simulations, visualizations, and performance metrics. Integrate multi-source sensor data, enhance algorithms, document processes, and collaborate with engineers, analysts, mission partners, and stakeholders in an agile environment.

Perform quantitative analysis, develop decision-support visualizations, and build Python software for data pipeline operations on a geospatial intelligence program. Analyze EO and SAR imagery, process complex geospatial data, and support AI/ML systems through ETL, SQL/NoSQL databases, and data manipulation. The role requires prior overhead imagery experience and an active TS/SCI clearance, with desired experience in NLP, computer vision, automated collection, and statistical modeling.