Top Senior Machine Learning Jobs in St. Louis, MO

Leads Toast’s AI and analytics strategy for Enterprise Care. Owns the roadmap, evaluates and deploys AI-assisted support tools, develops operational intelligence products, and partners with Product, Engineering, and Data teams to move pilots into production. Establishes complexity and workload intelligence, assesses AI readiness, translates AI performance into measurable operational outcomes, and builds organizational AI literacy. The role requires extensive enterprise support or service-delivery leadership, hands-on production AI experience, operational data fluency, and the ability to drive trusted adoption among agents and executives.

Build and productionize traditional machine learning models, owning feature engineering, validation, deployment, monitoring, drift detection, and retraining. Develop LLM-powered agentic tools, dashboards, self-serve analytics products, and automated insight pipelines. Partner with engineering and business stakeholders, write production-grade Python and SQL, drive adoption, improve data quality, and establish responsible AI workflows for a regulated industry.

Designs and implements scalable AI, machine learning, automation, and generative AI solutions for clients. Responsibilities include assessing AI readiness, developing strategies, leading discovery and solution delivery, integrating AI with enterprise systems, advising on governance and responsible AI, managing client engagements, contributing to reusable AI offerings, and supporting business development. The role requires strong technical, consulting, communication, and stakeholder management skills.

Own and improve Headway’s privacy program across HIPAA, 42 CFR Part 2, state privacy laws, individual rights, incidents, vendor governance, and AI use. Maintain controls, data maps, metrics, training, and operational workflows. Conduct product, vendor, and AI privacy assessments; manage rights requests and incident investigations; coordinate notifications and regulatory submissions; and translate complex requirements into practical guidance for cross-functional teams.

Develop autonomy evaluation metrics, statistical and machine-learning analyses, dashboards, and pipelines for simulation and on-road autonomous vehicle testing. Analyze perception, prediction, and planning performance; identify anomalous behavior and critical scenarios; apply VLMs and LLMs where appropriate; and support release gating and safety decisions. The role requires production Python, C++ debugging, technical leadership, cross-functional collaboration, and rigorous software engineering practices.

Define architecture and metrics for autonomous driving evaluation, lead cross-functional integration across autonomy and simulation teams, develop statistical and machine learning methods, analyze large-scale time-series data, manage evaluation KPIs and release gates, and communicate safety and readiness insights through dashboards and stakeholder presentations.

Serves as the technical bridge between customers, Sales, and technology teams. Leads technical discovery, solution architecture, demonstrations, workshops, proofs of concept, and evaluations using HERE data, APIs, mapping, routing, spatial analytics, cloud, AI, and enterprise integration. Partners with Sales to qualify opportunities, reduce technical risk, develop proposals and reusable presales assets, and guide customers toward location-intelligence solutions.

Lead AI engineering teams to design, build, and deploy end-to-end AI solutions. Manage client relationships, plan and deliver projects, mentor staff, drive adoption of cloud-native microservices, CI/CD, vector databases and orchestration tools, and ensure high standards of quality, innovation, and compliance.

Lead teams applying advanced data science and machine learning to large-scale claims, clinical, and member data to generate actionable insights that reduce cost of care and improve population health. Manage client relationships, mentor staff, ensure project delivery and quality, develop payer-focused analytics products, present findings to senior stakeholders, and promote continuous improvement and knowledge sharing.

Design and lead the technical strategy for search across Vannevar’s products. Build and improve full-text, vector, and LLM-powered retrieval systems, optimizing latency, relevance, index quality, freshness, and performance. Collaborate with ML, product, design, and mission strategy teams to translate user needs into search innovations. Apply expertise in information retrieval, NLP, machine learning, indexing, ranking, query parsing, tokenization, vector search, and evaluation frameworks.

Supports commercial enterprise sales by discovering customer requirements, aligning SailPoint solutions, delivering demonstrations, responding to RFPs, and leading Proof of Value evaluations. The role partners with sales, product, customer success, professional services, and channel teams while communicating technical and business value to IT and business stakeholders. It requires substantial pre-sales experience, enterprise software knowledge, SaaS architecture familiarity, and expertise in identity governance and access management.

Lead Runpod’s Americas sales organization and revenue number across new business, expansion, and renewals. Manage and coach Account Executives and Account Managers, oversee forecasting and pipeline, lead complex enterprise deals and contract negotiations, build regional go-to-market strategy and sales playbooks, and convert product-led demand into revenue. Partner with Marketing, Product, Legal, and Finance while improving sales efficiency through AI and developing a remote-first team.

Develops and validates machine learning and statistical models for anti-money laundering, transaction monitoring, customer screening, and risk rating. The role evaluates AML data quality, integrates vendor solutions, maintains governance and regulatory documentation, leads model lifecycle quality control, and reports performance through management dashboards. It also supports AML risk assessments, audits, regulatory examinations, and cross-functional stakeholder coordination.

Lead and scale a global team of Principal Agentic Technologists supporting strategic enterprise sales. Define technical sales methodologies, demonstrations, and proof-of-value frameworks for AI agent and non-human identity security products. Partner with sales, product, marketing, and engineering leaders to support major deals, influence product roadmaps, develop enablement programs, and communicate technical value to executives and architects.

The role involves deploying and supporting CrowdStrike's AI capabilities in cybersecurity, optimizing threat detection, and mentoring teams on AI solutions.

The Senior Data Scientist will analyze data to drive product strategy, optimize performance, and support product launches, collaborating with cross-functional teams.

Lead Amazon performance marketing strategy and execution, manage Sponsored Ads and DSP, collaborate with agencies and cross-functional teams, optimize campaigns and budgets, analyze performance with AMC/analytics, and measure commercial impact to drive ROAS and customer acquisition.

Lead corporate communications strategy and execution: own product and model launches, media and executive communications, narratives, social presence, and major company moments. Translate technical research and product advances into compelling stories for developers, enterprise buyers, partners, and analysts. Partner cross-functionally with CEO, CMO, product, brand, and demand gen to build credibility and influence in the voice AI ecosystem.

Own and execute multi-year strategic partnerships with a hyperscaler and an AI lab, aligning technical integrations, commercial motions, and joint go-to-market plans. Coordinate cross-functional teams, run operational cadences, track measurable outcomes (pipeline, ARR, integrations), and represent partnerships to executives while driving hands-on execution and follow-through.

Lead end-to-end delivery of AI and ML services within Managed Services. Manage project planning, budgeting, execution, and quality. Mentor and develop team members, cultivate client relationships, implement model monitoring and operationalization practices, and collaborate with architects and engineers to ensure compliant, reusable AI solutions.

Lead CrowdStrike Finance & Accounting AI transformation: define operating model and governance, prioritize AI use cases, oversee POC-to-production delivery, drive enablement and change management, measure benefits realization, and report outcomes to executives.

Leads technical pre-sales and foundational implementation engagements for SailPoint SaaS solutions. Discovers customer requirements, maps them to product capabilities, delivers proof-of-value implementations, explains architecture and best practices, and collaborates with sales, product, services, and customer success teams. Develops AI and agentic technology solutions for demonstrations and customer problems, while serving as a technical and consultative advisor to customers, partners, and colleagues.

Lead technical customer engagements for strategic accounts, supporting sales, solution design, foundational implementations, and proof-of-value deployments. Discover requirements, map them to SailPoint solutions, educate customers on architecture and best practices, collaborate across sales, product, professional services, and customer success, and develop AI- and agentic-technology solutions for demonstrations and customer outcomes.

Forward Deployed Engineers support sales and customer engagements by discovering requirements, designing and implementing foundational SaaS solutions, delivering proof-of-value implementations, and educating customers on architecture and best practices. They collaborate with sales, product, professional services, and customer success teams; use AI and agentic technologies to solve customer problems; lead technical engagements; document requirements; and develop reusable demonstration solutions. The role may require up to 15% travel.

Forward Deployed Engineers support enterprise sales and customer engagements by discovering requirements, mapping them to SailPoint solutions, and delivering foundational implementations and proof-of-value projects. They provide technical leadership, explain architecture and best practices, collaborate across sales, product, services, and customer success teams, and develop AI- and agentic-technology solutions for demonstrations and customer problems. The role requires strong client communication, software implementation expertise, SaaS architecture knowledge, and familiarity with enterprise infrastructure and identity governance.